Neuropathy yechipiri kune zvinodhaka

Neuropathy kukuvara kumitsipa yenharaunda. Iyi ndiyo tsinga isiri muuropi kana musana. Neuropathy yechipiri kune zvinodhaka kurasikirwa kwekunzwa kana kufamba mune chimwe chikamu chemuviri nekuda kwekukuvara kwetsinga kubva pakutora mumwe mushonga kana musanganiswa wemishonga.

Iko kukuvara kunokonzerwa nehuturu mhedzisiro yemimwe mishonga pane yekumusoro tsinga. Panogona kuve nekukuvara kune iyo axon chikamu chetsinga sero, iyo inokanganisa zviratidzo zvetsinga. Kana, iyo kukuvara kunogona kusanganisira iyo myelin sheath, iyo inodzivirira maazoni uye inowedzera kumhanyisa kwekufambisa kwemasaini kuburikidza neaxon.

Kazhinji kazhinji, tsinga zhinji dzinobatanidzwa (polyneuropathy). Izvi zvinowanzo kukonzera shanduko yekunzwa iyo inotanga munzvimbo dzekunze dzemuviri (distal) uye inofamba ichienda pakati pomuviri (proximal). Panogona zvakare kuve neshanduko mukufamba, senge kushaya simba. Panogona zvakare kuve nekupisa kurwadziwa.

Mishonga yakawanda uye zvinhu zvinogona kutungamira mukusimudzira kweuropathy. Mienzaniso yakanyorwa pazasi.

Mwoyo kana kuwedzerwa kweropa zvinodhaka:

• Amiodarone
• Hydralazine
• Perhexiline

Zvinodhaka zvinoshandiswa kurwisa cancer.

• Cisplatin
• Docetaxel
• Paclitaxel
• Kuongorora
• Vincristine

Zvinodhaka zvinoshandiswa kurwisa hutachiona:

• Chloroquine
• Dapsone
• Isoniazid (INH), inoshandiswa kurwisa tibhii
• Metronidazole (Flagyl)
• Nitrofurantoin
• Thalidomide (inoshandiswa kurwisa maperembudzi)

Zvinodhaka zvinoshandiswa kurapa autoimmune chirwere:

• Etanercept (Enbrel)
• Infliximab (Remicade)
• Leflunomide (Arava)

Mishonga inoshandiswa kurapa pfari:

• Carbamazepine
• Phenytoin
• Phenobarbital

Anti-doro zvinodhaka:

• Disulfiram

Zvinodhaka kurwisa HIV / AIDS:

• Didanosine (Videx)
• Emtricitabine (Emtriva)
  
• Stavudine (Zerit)
• Tenofovir uye emtricitabine (Truvada)

Mimwe mishonga uye zvinhu zvinogona kukonzera neuropathy zvinosanganisira:

• Colchicine (inoshandiswa kurapa gout)
• Disulfiram (yaishandiswa kurapa kunwa doro)
• Arsenic
• Ndarama

Zviratidzo zvinogona kusanganisira chero zvinotevera:

• Chiveve, kurasikirwa kwekunzwa
• Kuchera, kusanzwisisika kwekunzwa
• Kushaya simba
• Kupisa kurwadziwa

Kuchinja kwekunzwa kunowanzotanga mutsoka kana maoko uye kufamba mukati.

Uropi uye huta hurongwa hwekuongorora huchaitwa.

Mimwe bvunzo inosanganisira:

• Kuongororwa kweropa kutarisa mwero wemushonga (kunyangwe akajairwa ropa mazinga emamwe madhiragi angave ane chepfu kuvanhu vakuru kana vamwe vanhu)
• EMG (electromyography) uye nerve conduction bvunzo yemagetsi mashandiro etsinga nemhasuru

Kurapa kunoenderana nezviratidzo uye kuti zvakakomba sei. Iyo mishonga inokonzeresa iyo neuropathy inogona kumiswa, kudzikiswa muyero, kana kuchinjirwa kune mumwe mushonga. (Usambofa wakachinja chero mushonga usati watanga kutaura nemupi wako wezvehutano.)

Wako mupi anogona kupa anotevera mishonga kuti ubatsire kudzora marwadzo:

• Kupfuura-the-counter kurwadziwa kunodzora kunogona kubatsira pakurwadziwa kwakapfava (neuralgia).
• Phenytoin, carbamazepine, gabapentin, pregabalin, duloxetine, kana tricyclic mishonga yekudzvinyirira senge nortriptyline inogona kudzora marwadzo ekurova anowanikwa nevamwe vanhu.
• Opiate pain relievers, senge morphine kana fentanyl, inogona kudiwa kudzora kurwadziwa kwakanyanya.

Ikozvino hapana mishonga inogona kudzosera kurasikirwa kwekunzwa. Kana iwe warasikirwa neshungu, ungangoda kutora matanho ekudzivirira kudzivirira kukuvara.

Kumbira mupiki wako kana paine maekisesaizi ayo anogona kubatsira kubvisa zviratidzo zvako.

Vanhu vazhinji vanogona kudzoka zvishoma kana zvizere kuita kwavo kwakajairika basa. Chirwere hachiwanzo kukonzera matambudziko ekutyisidzira hupenyu, asi chinogona kusagadzikana kana kuremadza.

Zvinetso zvinogona kusanganisira:

• Kusakwanisa kushanda pabasa kana pamba nekuda kwekurasikirwa zvachose kwekunzwa
• Marwadzo nekurumwa munzvimbo yekukuvara kwetsinga
• Kurasikirwa zvachose kwekunzwa (kana kashoma, kufamba) munzvimbo

Fonera mupiki wako kana iwe uine kurasikirwa kwekunzwa kana kufamba kwechero nzvimbo yemuviri uchitora chero mushonga.

Wako mupi achanyatso tarisa kurapwa kwako nechero mushonga ungakonzere neuropathy. Chinangwa ndechekuchengetedza iro rakaringana ropa chiyero chechinodhaka chinodiwa kudzora chirwere uye zviratidzo zvacho uchidzivirira mushonga kuti usasvika pamwero une chepfu.

• Central nervous system uye yekumusoro tsinga system

Jones MR, Kurudzira I, Wolf J, et al. Zvinodhaka-zvinokonzeresa peripheral neuropathy, rondedzero ongororo. Curr Clin Pharmacol. Ndira 2019. PMID: 30666914 www.ncbi.nlm.nih.gov/pubmed/30666914.

Katirji B. Kukanganisika kwemitsipa yekunze. Mune: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology muClinical Dzidzira. 7th ed. Philadelphia, PA: Elsevier; 2016: chits. 107.

O'Connor KDJ, Mastaglia FL. Zvinodhaka zvinokonzerwa nezvinodhaka zvehurongwa hwemitsipa. Mune: Aminoff MJ, Josephson SA, eds. Aminoff's Neurology uye General Medicine. 5 ed. Waltham, MA: Elsevier Dzidzo Press; 2014: chits.