Neurosyphilis

Neurosyphilis chirwere chehutachiona chehuropi kana musana. Inowanzoitika kune vanhu vasina kurapwa syphilis kwemakore mazhinji.

Neurosyphilis inokonzerwa ne Treponema pallidum. Aya ndiwo mabhakitiriya anokonzera syphilis. Neurosyphilis inowanzoitika anenge makore gumi kusvika makumi maviri mushure mekunge munhu atanga kubatwa nechirwere. Haasi munhu wese ane syphilis anovandudza dambudziko iri.

Kune mana mafomu akasiyana eurosophysis:

• Asymptomatic (yakajairika fomu)
• General paresis
• Meningovascular
• Tabes dorsalis

Asymptomatic neurosyphilis inoitika pamberi pezviratidzo zvechirwere. Asymptomatic zvinoreva kuti hapana chero zviratidzo.

Zviratidzo zvinowanzo kukanganisa huta hurongwa. Zvichienderana nechimiro cheeurosyphilis, zviratidzo zvinogona kusanganisira chero zvinotevera:

• Kufamba zvisina kujairika (gait), kana kusakwanisa kufamba
• Unhu muzvigunwe, tsoka, kana makumbo
• Matambudziko nekufunga, senge kuvhiringidzika kana kutadza kuisa pfungwa
• Matambudziko epfungwa, senge kushushikana kana kutsamwa
• Kutemwa nemusoro, kugwinha, kana kuomesa mutsipa
• Kurasikirwa kwedundira kudzora (kusagadzikana)
• Kudedera, kana kushaya simba
• Zvinetso zvekuona, kunyangwe bofu

Anokupa hutano anozoongorora uye anogona kuwana zvinotevera:

• Kusanzwisisika kusagadzikana
• Tsvina atrophy
• Tsvina yemhasuru
• Kuchinja kwepfungwa

Kuongororwa kweropa kunogona kuitwa kuti uone zvinhu zvinogadzirwa nehutachiona hunokonzera syphilis, izvi zvinosanganisira:

• Treponema pallidum PARTICIPLE agglutination munhu akaidza (TPPA)
• Venereal chirwere chekuongorora marabhoritari (VDRL) bvunzo
• Fluorescent treponemal antibody absorption (FTA-ABS)
• Inokurumidza plasma reagin (RPR)

Iine neurosyphilis, zvakakosha kuyedza musana wemvura kune zviratidzo zve syphilis.

Kuyedza kutsvaga matambudziko nehurongwa hwemitsipa kunogona kusanganisira:

• Cerebral angiogram
• Musoro CT scan
• Lumbar puncture (spinal tap) uye cerebrospinal fluid (CSF) ongororo
• MRI scan yehuropi, brainstem, kana musana

Iyo antibiotic penicillin inoshandiswa kurapa neurosyphilis. Inogona kupihwa nenzira dzakasiyana:

• Yakabayiwa mutsinga kakawanda pazuva kwemazuva gumi kusvika gumi nemana.
• Nemuromo kanokwana ka4 pazuva, zvichisanganiswa nemajekiseni ezuva nezuva etsinga, ese anotorwa kwemazuva gumi kusvika gumi nemana.

Iwe unofanirwa kuve nekutevera-kuongorora ropa pa3, 6, 12, 24, uye 36 mwedzi kuti uve nechokwadi chekuti hutachiona hwaenda. Iwe unozoda yekutevera-lumbar punctures yeCSF ongororo yega yega mwedzi mitanhatu. Kana uine hutachiwana hweHIV / AIDS kana chimwe chirwere, yako yekutevera nguva inogona kunge yakasiyana.

Neurosyphilis kuomarara kwehupenyu njovhera. Kunyatsoita kwaunoita kunoenderana nekuti yakanyanya sei neurosyphilis isati yarapwa. Chinangwa chekurapa ndechekudzivirira kumwe kuora. Zvizhinji zvekuchinja uku hazvidzoreke.

Zviratidzo zvinogona kuwedzera zvishoma nezvishoma.

Fonera mupi wako kana iwe uine syphilis munguva yakapfuura uye ikozvino une zviratidzo zvehurongwa hwehurongwa hwematambudziko.

Kukurumidza kuongororwa uye kurapwa kweiyo yekutanga syphilis hutachiona kunogona kudzivirira neurosyphilis.

Njovhera - neurosyphilis

• Central nervous system uye yekumusoro tsinga system
• Late-danho njovhera

Euerle BD. Spinal kubaya uye cerebrospinal fluid kuongorora. Mune: Roberts JR, Custalow CB, Thomsen TW, eds. Roberts uye Hedges 'Clinical Maitiro muEmergency Medicine uye Acute Kuchengeta. 7th ed. Philadelphia, PA: Elsevier; 2019: chitsiko 60.

National Institute yeNeurological Dambudziko uye Stroke webhusaiti. Neurosyphilis. www.ninds.nih.gov/Disorders/All-Disorders/Neurosyphilis-Information-Page. Yakagadziridzwa Kurume 27, 2019. Yakasvika munaFebruary 19, 2021.

Radolf JD, Tramont EC, Salazar JC. Njovhera (Treponema pallidum). Mune: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, uye Bennett's Maitiro uye Maitiro Ezvirwere zvinotapukira. 9th ed. Philadelphia, PA: Elsevier; 2020: chitsiko 237.