Yakashata hyperthermia

Malignant hyperthermia (MH) chirwere chinokonzeresa kumhanya kwekushisa kwemuviri uye mhasuru dzakakomba musuru kana mumwe munhu ane MH awana anesthesia yakajairika. MH inopfuudzwa kuburikidza nemhuri.

Hyperthermia zvinoreva tembiricha yepamusoro yemuviri. Aya mamiriro haana kufanana ne hyperthermia kubva kune zvekukurumidzira zvekurapa senge kupisa kupisa kana chirwere.

MH inogarwa nhaka. Mubereki mumwe chete ndiye anofanira kutakura chirwere kuti mwana agare nhaka mamiriro acho.

Zvinogona kuitika nezvimwe zvirwere zvemhasuru zvakagarwa nhaka, senge multiminicore myopathy uye chepakati chirwere chepakati.

Zviratidzo zveMH zvinosanganisira:

• Kubuda ropa
• Rima rakasviba weti (nekuda kweprotein yemhasuru inonzi myoglobin mumugini)
• Tsvina inorwadza pasina chikonzero chiri pachena, senge kurovedza muviri kana kukuvara
• Tsigisa kuomarara uye kuomarara
• Simuka mutembiricha yemuviri kusvika 105 ° F (40.6 ° C) kana kupfuura

MH inowanzo kuwanikwa mushure mekunge munhu apihwa anesthesia panguva yekuvhiyiwa.

Panogona kunge paine nhoroondo yemhuri yeMH kana kufa kusingatsanangurike panguva yeanesthesia.

Munhu wacho anogona kunge aine yekutsanya uye kazhinji isina kujairika kurova kwemoyo.

Miedzo yeMH inogona kusanganisira:

• Ropa rekuvhara ropa zvidzidzo (PT, kana prothrombin nguva; PTT, kana chikamu chetromboplastin nguva)
• Ropa kemisitiri wepaneru, kusanganisira CK (creatinine kinase, iri pamusoro muropa kana mhasuru yaparadzwa panguva yechirwere)
• Genetic kuyedza kutarisa hurema mumajene ayo akabatana nechirwere
• Tsvina biopsy
• Weti myoglobin (mhasuru protein)

Munguva yechiitiko cheMH, mushonga unonzi dantrolene unowanzo kupihwa. Kuputira munhu wacho mugumbeze kunotonhodza kunogona kubatsira kudzikisa kupisa muviri uye njodzi yezvinetso zvakakomba.

Kuchengetedza itsvo kushanda panguva yechiitiko, munhu anogona kugamuchira zvinwiwa kuburikidza nemutsinga.

Izvi zviwanikwa zvinogona kupa rumwe ruzivo nezve MH:

• Malignant Hyperthermia Association yeUnited States - www.mhaus.org
• National Sangano reRare Dambudziko - rarediseases.org/rare-diseases/malignant-hyperthermia
• NIH Genetics Kumba Referensi - ghr.nlm.nih.gov/condition/malignant-hyperthermia

Zvikamu zvinodzokororwa kana zvisina kurapwa zvinogona kukonzera kutadza kweitsvo. Zvikamu zvisina kurapwa zvinogona kuuraya.

Aya matambudziko akakomba anogona kuitika:

• Kudimburwa
• Kuparara kwemhasuru yemhasuru
• Kuzvimba kwemaoko nemakumbo uye matambudziko neropa kuyerera uye tsinga basa (compartment syndrome)
• Rufu
• Ropa risina kujairika rinovhara uye kubuda ropa
• Matambudziko emoyo mutinhimira
• Itsvo kutadza
• Kuvaka kweacid mumuviri wemvura (metabolic acidosis)
• Mvura inovaka mumapapu
• Misungo isina simba kana yakaremara (myopathy kana muscular dystrophy)

Kana iwe uchida kuvhiyiwa, udza vese chiremba wako anovhiya uye anesthesiologist usati wavhiyiwa kana:

• Iwe unoziva kuti iwe kana nhengo yemhuri yako wakambove nematambudziko neakajairirika anesthesia
• Iwe unoziva iwe une nhoroondo yemhuri yeMH

Kushandisa mimwe mishonga kunogona kudzivirira kunetseka kweMH panguva yekuvhiyiwa.

Udza mupi wako wezvehutano usati wavhiyiwa neanesthesia, kana iwe kana chero munhu mumhuri yako ane MH.

Dzivisa zvinodhaka zvinokurudzira zvakadai secocaine, amphetamine (speed), uye ecstasy. Iyi mishonga inogona kukonzera matambudziko akafanana neMH mune vanhu vakajairwa nemamiriro aya.

Genetic counselling inokurudzirwa kune chero munhu ane mhuri nhoroondo yemyopathy, muscular dystrophy, kana MH.

Hyperthermia - yakaipa; Hyperpyrexia - yakaipa; MH

American Association yeMukoti Anesthetists. Malignant hyperthermia dambudziko kugadzirira uye kurapwa: chinzvimbo chirevo. www.aana.com/docs/default-source/practice-aana-com-web-documents-(all)/malignant-hyperthermia-crisis-preparedness-and-treatment.pdf?sfvrsn=630049b1_8. Yakagadziridzwa Kubvumbi 2018. Yakasvika muna Chivabvu 6, 2019.

Kulaylat MN, Dayton MT. Matambudziko ekuvhiya. Mu: Townsend CM Jr, Beauchamp RD, Evers BM, Mattox KL, eds. Sabiston Chinyorwa Chekuvhiya. 20th ed. Philadelphia, PA: Elsevier; 2017: chits. 12.

Zhou J, Bose D, Allen PD, Pessah IN. Malignant hyperthermia uye kusagadzikana kwakanangana nemhasuru. Mune: Miller RD, ed. Anesthesia yaMiller. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015: chits. 43.