Chinhu VIII kuyedza
Iyo factor VIII kuyedza ndiko kuongororwa kweropa kuyera chiitiko cheichi chinhu VIII. Iyi ndiyo imwe yemapuroteni mumuviri anobatsira iro ropa kugwamba.
Muenzaniso weropa unodiwa.
Hapana gadziriro inokosha inodiwa.
Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurohwa kana kupwanya zvishoma. Izvi zvinokurumidza kuenda.
Muedzo uyu unoshandiswa kutsvaga chinokonzera kubuda ropa rakawanda (kudzikira kweropa). Kana, inogona kurairwa kana nhengo yemhuri ichizivikanwa kuti ine hemophilia A. Muedzo unogona kuitwawo kuti uone kuti kurapa hemophilia A kuri kushanda sei.
Iyo yakasarudzika kukosha ndeye 50% kusvika 200% yeiyo laboratory kudzora kana kukosha kukosha.
Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Mamwe marabhu anoshandisa zviyero zvakasiyana kana anogona kuyedza masampuli akasiyana. Taura nemupi wako wezvehutano nezve zvinorehwa nemimwe miedzo yako.
Kupera kwechinhu VIII chiitiko chingave chakakonzerwa ne:
- Hemophilia A (chirwere chekubuda ropa chinokonzerwa nekushaikwa kweropa rinovhara chinhu VIII)
- Kuvhiringidzika uko mapuroteni anodzora kugwamba kweropa anova pamusoro peanoshanda anoparadzirwa intravascular coagulation (DIC)
- Kuvapo kweFactor VIII inhibitor (antibody)
- Von Willebrand chirwere (rumwe rudzi rwekubuda ropa kusagadzikana)
Kuwedzera chiitiko kunogona kunge kuri nekuda kwe:
- Kukwegura
- Chirwere cheshuga
- Chiropa chirwere
- Kuzvimba
- Kubata pamuviri
- Kufutisa
Pane njodzi shoma inosanganisirwa nekutorwa kweropa rako. Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe, uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kuwana muyero weropa kubva kune vamwe vanhu kunogona kunetsa kupfuura kune vamwe.
Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:
- Kuwedzera kubuda ropa
- Kufenda kana kunzwa kushaya musoro
- Akawanda punctures ekutsvaga mutsinga
- Hematoma (ropa rinoungana pasi peganda)
- Utachiona (hushoma njodzi chero nguva ganda parinovhunika)
Muedzo uyu unowanzoitwa kune vanhu vane matambudziko ekubuda ropa. Ngozi yekubuda ropa kwakanyanya yakati kurei kune vanhu vane matambudziko ekubuda ropa kupfuura vamwe.
Plasma factor VIII antigen; Antihemophilia chinhu; AHF
Carcao M, Moorehead P, Lillicrap D.Hemophilia A uye B. Muna: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Misimboti uye Maitiro. 7th ed. Philadelphia, PA: Elsevier; 2018: chits. 135.
Chernecky CC, Berger BJ. Chinhu VIII (antihemophilia factor, AHF) - ropa. Mune: Chernecky CC, Berger BJ, eds. Rabhoritari Kuyedza uye Maitiro Ekuongorora. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 504-505.
Napolitano M, Schmaier AH, Kessler CM. Coagulation uye fibrinolysis. Mune: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis uye Management nemaLabhoritari Maitiro. 23rd ed. St Louis, MO: Elsevier; 2017: chits. 39.