Fecal microbiota kuisazve

Fecal microbiota transplantation (FMT) inobatsira kutsiva mamwe mabhakitiriya "akaipa" ekoloni yako ne "akanaka" mabhakitiriya. Maitiro acho anobatsira kudzorera mabhakitiriya akanaka akaurayiwa kana kuderedzwa nekushandiswa kwemishonga inorwisa mabhakitiriya. Kudzorera chiyero ichi mukoloni kunoita kuti zvive nyore kurwisa hutachiona.

FMT inosanganisira kuunganidza zvigaro kubva kune anopa hutano. Anopa hutano hwako anokumbira iwe kuti uone mupi. Vanhu vazhinji vanosarudza nhengo yemhuri kana shamwari yepedyo. Mupiro haafanire kunge akashandisa maantibayoti kwemazuva maviri kusvika matatu apfuura. Vanozovhenekwa chero hutachiona muropa kana zvigaro.

Kana yangounganidzwa, cheya yemupi wemupiro inosanganiswa nemvura ine munyu uye inosvinwa. Musanganiswa wesituru unozoendeswa mukati medu yekugaya (colon) kuburikidza netubhu inopfuura nekolonoscope (yakatetepa, inochinja chubhu ine kamera diki). Hutachiona hwakanaka hunogona zvakare kuunzwa mumuviri nenzira yechubhu inopinda mudumbu kuburikidza nemuromo. Imwe nzira ndeyekumedza kapsule iyo ine chando-chakaomeswa chevapi vetsvina.

Ura hwakakura hune huwandu hukuru hwehutachiona. Aya mabhakitiriya anogara mumatumbu ako akakosha kune hutano hwako, uye anokura nenzira yakaenzana.

Imwe yeaya mabhakitiriya anonzi Clostridioides difficile (C chakasiyana). Mune zvishoma, hazvikonzeri matambudziko.

• Nekudaro, kana munhu akagashira akadzokororwa kana akakwirira madosi emishonga inorwisa mabhakitiriya kune hutachiona kumwe kunhu mumuviri, mazhinji ebhakitiriya akajairwa mumatumbu anogona kutsvairwa Utachiona hunokura uye hunoburitsa chepfu.
• Mhedzisiro yacho inogona kunge iri yakawandisa yeiyo C difficile.
• Iyi chepfu inokonzeresa kuti mubato wemuura muhombe kuzvimba uye kuzvimba, zvichikonzera fivha, manyoka, uye kubuda ropa.

Mamwe maantibhakitiriya anogona dzimwe nguva kuunza iyo C difficile mabhakitiriya ari pasi pesimba. Kana izvi zvikasabudirira, FMT inoshandiswa kutsiva zvimwe zve C difficile ne "zvakanaka" mabhakitiriya uye dzorera chiyero.

FMT zvakare inogona kushandiswa kurapa mamiriro akadai se:

• Irritable bowel chirwere
• Chirwere cheCrohn
• Kuzvimbirwa
• Ulcerative colitis

Kurapa kwemamwe mamiriro kunze kwekudzokororwa C difficile colitis inoonekwa seyedzwa parizvino uye haisi kushandiswa zvakanyanya kana kuzivikanwa kunge inoshanda.

Ngozi dzeFMT dzinogona kusanganisira zvinotevera:

• Reaction kumushonga iwe waunopihwa panguva yekuita
• Ropa rinorema kana rinoramba richienderera panguva yekuita
• Matambudziko ekufema
• Kupararira kwechirwere kubva kune iye mupi (kana mupi asina kuongororwa zvakanaka, izvo zvisingawanzoitika)
• Utachiona panguva yekolonoscopy (zvisingawanzoitika)
• Ropa clots (zvisingawanzoitika)

Mupiro angangotora laxative husiku hwakatangira maitiro kuitira kuti vagone kufambisa ura mangwanani anotevera. Ivo vanozotora stool sampuro mukapu yakachena uye vouya nayo navo zuva remaitiro.

Taura nemupi wako nezve chero allergiki uye mishonga yese yauri kutora. Usarege kutora chero mushonga usati wataura kune wako mupi. Iwe unozofanirwa kumira kutora chero maantibayoti kwemazuva maviri kusvika matatu usati waitwa.

Iwe ungangoda kutevera chikafu chemvura. Iwe unogona kukumbirwa kutora laxatives usiku hwakatangira maitiro. Iwe unozofanirwa kugadzirira colonoscopy husiku hwakatangira FMT. Chiremba wako achakupa rairo.

Maitiro acho asati aitwa, iwe unozopihwa mishonga yekukuita kuti uve nehope kuitira kuti usazonzwa kusagadzikana kana kuve neyese yekurangarira bvunzo.

Iwe ucharara parutivi rwako kwemaawa anenge maviri mushure mekuita pamwe nemhinduro mumatumbu ako. Iwe unogona kupihwa loperamide (Imodium) kubatsira kubatsira kudzikisa ura hwako kuitira kuti mhinduro igare iri panzvimbo panguva ino.

Iwe uchaenda kumba zuva rimwe chetero remaitiro kana iwe uchinge wapfuura musanganiswa wechigaro. Iwe unozoda kukwira kuenda kumba, saka ive shuwa yekuronga pamberi penguva. Iwe unofanirwa kudzivirira kutyaira, kunwa doro, kana chero chinorema kusimudza.

Iwe unogona kunge uine yakaderera-giredhi fivha husiku hwakatevera maitiro. Iwe unogona kunge uchiputika, gasi, flatulence, uye kupatira kwemazuva mashoma mushure mekuita.

Mupiki wako anokurairidza nezverudzi rwekudya uye mishonga yaunoda kutora mushure mekuita.

Iyi yekurapa inoponesa hupenyu yakachengeteka kwazvo, inoshanda uye, yakaderera mutengo. FMT inobatsira nekudzosa yakajairwa flora kuburikidza neanopa chetsoka. Izvi zvinobva zvabatsira mukudzoreredza chako chaicho ura mashandiro uye hutano.

Fecal bacteriotherapy; Stool kuisazve; Kuisa fecal; C. difficile colitis - fecal kuisazve; Clostridium difficile - fecal kuisazve; Clostridioides difficile - fecal kuisazve; Pseudomembranous colitis - fecal kuisazve

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Rao K, Safdar N. Fecal microbiota kuisirwa kurapwa kweClostridium difficile hutachiona. J Hosp Med. 2016; 11 (1): 56-61. PMID: 26344412 www.ncbi.nlm.nih.gov/pubmed/26344412.

Schneider A, Maric L. Fecal microbiota kuisirwa senzira yekurapa kwehutachiona chirwere. Mune: Shen B, ed. Inopindirana Inoputira Bowel Chirwere. San Diego, CA: Elsevier Dzidzo Press; 2018: chitsiko 28.

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