Munyori: Clyde Lopez
Zuva Rekusika: 23 Chikunguru 2021
Gadziridza Zuva: 14 Mbudzi 2024
Anonim
Mycophenolic Acid - Mycophenolate (organ transplant and DMARD) - mechanism of action, side effects
Vhidhiyo: Mycophenolic Acid - Mycophenolate (organ transplant and DMARD) - mechanism of action, side effects

Zvemukati

Ngozi yekuremara kwekuberekwa:

Mycophenolate haifanire kutorwa nevakadzi vane nhumbu kana vanogona kuve nepamuviri. Pane njodzi huru yekuti mycophenolate inokonzeresa kuenda pamuviri (kurasikirwa nepamuviri) mukati memwedzi mitatu yekutanga yekubata kana kukonzera mwana kuti azvarwe aine hurema hwekuzvara (matambudziko aripo pakuzvarwa).

Iwe haufanire kutora mycophenolate kana iwe uine pamuviri kana kana iwe ungangove nepamuviri. Iwe unofanirwa kuve nemimba isina nhumbu bvunzo usati watanga kurapwa kwako ne mycophenolate, zvakare mazuva masere kusvika gumi gare gare, uye panguva dzekuteedzera dzinoteedzana. Iwe unofanirwa kushandisa inogamuchirwa yekuberekwa panguva yekurapa kwako, uye kwemavhiki matanhatu mushure mekumira kutora mycophenolate. Chiremba wako anokuudza kuti ndedzipi nzira dzekudzivirira kuberekwa dzinogamuchirwa kuti iwe ushandise. Mycophenolate inogona kudzikisira kushanda kwemakemikari ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka), saka zvakanyanya kukosha kushandisa fomu yechipiri yekudzivirira kuberekwa pamwe nemhando iyi yekudzivirira.

Kana iwe uri murume ane mukadzi mukadzi uyo anogona kuve nepamuviri, iwe unofanirwa kushandisa inogamuchirwa yekuzvarwa pakuberekwa panguva yekurapa uye kwemazuva angangoita makumi mapfumbamwe mushure meyako yekupedzisira dosi. Usape urume panguva yekurapa kwako uye kweinenge mazuva makumi mapfumbamwe mushure mekupedzisira kwedosi.


Fonera chiremba wako ipapo ipapo kana iwe uchifunga kuti iwe kana mumwe wako, ane nhumbu kana kana ukarasikirwa nemwedzi.

Nekuda kwekugona kuti chipo chako chinogona kuenda kumukadzi anogona kunge ari kana kuve nepamuviri, usape ropa panguva yekurapwa kwako uye kweanenge mavhiki matanhatu mushure medosi yako yekupedzisira.

Ngozi dzezvirwere zvakakomba:

Mycophenolate inoderedza immune immune uye inogona kudzora kugona kwako kurwisa hutachiona. Shamba maoko ako kazhinji uye dzivisa vanhu vari kurwara iwe uchinwa mushonga uyu. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, fonera chiremba wako nekukasira: fivha, huro huro, kutonhora, kana kukosora; kupwanya kusingawanzo kana kubuda ropa; kurwadziwa kana kupisa panguva yekuita weti; kugara uchiita weti; ronda kana ronda rakatsvuka, rinodziya, kana risingazopora; mvura kubva paganda ronda; Kazhinji kushaya simba, kuneta zvakanyanya, kana kurwara kunzwa; zviratidzo zve '' flu '' kana a '' kutonhora ''; kurwadziwa kana kuzvimba mumutsipa, kugomera, kana muhapwa; zvigamba zvichena mumuromo kana pahuro; maronda anotonhora; mhoni; musoro kana nzeve; kana zvimwe zviratidzo zvehutachiona.


Iwe unogona kutapukirwa nemamwe hutachiona kana mabhakitiriya asi usina kana zviratidzo zvehutachiona. Kutora mycophenolate kunowedzera njodzi yekuti hutachiona uhwu huchawedzera uye hunokonzera zviratidzo. Udza chiremba wako kana iwe uine chero hutachiona hutachiona, hwakadai seHepatitis B kana C, kusanganisira hutachiona husingaite zviratidzo.

Mycophenolate inogona kuwedzera njodzi yekuti iwe unozokura unofambira mberi multifocal leukoencephalopathy (PML; chirwere chisingawanzo chehuropi chisingakwanise kurapwa, kudzivirirwa, kana kurapwa uye izvo zvinowanzo kukonzera kufa kana kuremara kwakanyanya). Udza chiremba wako kana wakambove ne PML, kana chimwe chirwere chinokanganisa immune system yako sehutachiona hwehutachiona hwehutachiona hweHIV; akawana immunodeficiency syndrome (AIDS); sarcoidosis (mamiriro anokonzera kuzvimba mumapapu uye dzimwe nguva mune mamwe mativi emuviri); leukemia (kenza inokonzeresa masero eropa akawandisa kugadzirwa uye kuburitswa muropa); kana lymphoma. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, dana chiremba wako nekukurumidza: kushaya simba kune rumwe rutivi rwemuviri kana mumakumbo; kuoma kana kutadza kudzora mhasuru dzako; kuvhiringidzika kana kunetseka kufunga zvakajeka; kusagadzikana; kuyeuka ndangariro; kunetseka kutaura kana kunzwisisa zvinotaurwa nevamwe; kana kushaikwa kwekufarira kana hanya nezviitiko zvenguva dzose kana zvinhu zvaunowanzoitira hanya.


Mycophenolate inogona kuwedzera njodzi yako yekukudziridza mamwe marudzi ekenza, kusanganisira lymphoma (rudzi rwekenza runowanikwa mune lymph system) uye gomarara reganda. Udza chiremba wako kana iwe kana mumwe munhu mumhuri yako ane kana akambove nekenza yeganda. Dzivisa kuratidzwa kusiri madikanwa kana kwenguva refu kune chaiwo uye ekugadzira ezuva (kuchenesa mibhedha, mwenje wezuva) uye kurapa kwakareruka uye pfeka zvipfeko zvekudzivirira, magirazi ezuva, uye sunscreen (ine SPF chinhu che 30 kana pamusoro). Izvi zvinobatsira kudzikisa njodzi yako yekuva nekenza yeganda. Shevedza chiremba wako kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge ganda idzva rinorwadza kana bundu; shanduko muhukuru kana ruvara rwema mole; ganda rakasviba kana dema reganda (rakasuruvara) rine mitsetse isina kuenzana kana chimwe chikamu chechironda icho chisingaratidzika kunge chimwe; kuchinja kweganda; maronda asingapore; fivha isina kutsanangurwa; kuneta kusingaendi; kana kuonda.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro Rekurapa) paunotanga kurapwa ne mycophenolate uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti http://www.fda.gov/Drugs kuti uwane iwo mushonga weMedication.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako ku mycophenolate.

Taura nachiremba wako nezve njodzi dzekutora mycophenolate.

Mycophenolate (CellCept) inoshandiswa nemimwe mishonga kubatsira kudzivirira kuisirwa nhengo kurambwa (kurwisa kwechinhu chakaiswazve nedziviriro yemuviri yemunhu ari kugamuchira nhengo) kune vanhu vakuru vakagashira moyo nechiropa vanoisirwa uye muvanhu vakuru nevana vane mwedzi mitatu uye vakuru vakagashira itsvo. Mycophenolate (Myfortic) inoshandiswa nemimwe mishonga kubatsira kudzivirira muviri kubva pakuramba kuisirwa itsvo. Mycophenolate iri mukirasi yemishonga inonzi immunosuppressive agents. Inoshanda nekuderedza masimba ezvirwere zvemuviri saka haizorwisi uye kuramba nhengo yakaiswa.

Mycophenolate inouya sekapuleti, piritsi, kunonoka-kuburitsa (kuburitsa mushonga mumatumbu) piritsi, uye kumiswa (mvura) kutora nemuromo. Inowanzo kutorwa kaviri pazuva pane isina chinhu mudumbu (1 awa pamberi kana maviri maawa mushure mekudya kana kunwa, kunze kwekunge chiremba wako akakuudza neimwe nzira). Tora mycophenolate panenge panguva dzakafanana zuva rega rega, uye edza kuisa madosi ako anenge maawa gumi nemaviri akaparadzaniswa. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora mycophenolate chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Iyo mishonga mune yakanonoka-kuburitsa piritsi (Myfortic) inodhonzwa zvakasiyana nemuviri pane mushonga uri mukumiswa, piritsi, uye kapsule (CellCept). Izvi zvigadzirwa hazvigone kutsiva mumwe nemumwe. Nguva imwe neimwe paunonyorwa mushonga wako, ita shuwa kuti wagamuchira chigadzirwa chaicho. Kana iwe uchifunga kuti wagamuchira isiriyo mishonga, taura nachiremba wako uye wemishonga ipapo ipapo.

Medza mapiritsi, anonoka-kuburitsa mapiritsi, uye macapsule akazara; usatsemure, kutsenga, kana kuvapwanya. Usavhure macapsule.

Usasanganise mycophenolate kuturika nechero imwe mishonga.

Ive nekuchengera kuti usadurure kuturika kana kuimwaya paganda rako. Kana iwe ukawana kumiswa paganda rako, geza nzvimbo yacho zvakanaka nesipo nemvura. Kana iwe ukawana kumiswa mumaziso ako, sukurudza nemvura isina mvura. Shandisa yakanyorova mapepa matauro kupukuta chero zvadirwa mvura.

Mycophenolate inobatsira kudzivirira iyo nhengo kupinza kurambwa chete chero bedzi iwe uri kutora mushonga. Ramba uchitora mycophenolate kunyangwe iwe uchinzwa zvakanaka. Usarega kutora mycophenolate usina kutaura nachiremba wako.

Mycophenolate inoshandiswawo kurapa chirwere cheCrohn (mamiriro ezvinhu umo muviri unorwisa bhandi regwara rekudya, zvichikonzera marwadzo, manyoka, kuonda, uye fivha). Taura nachiremba wako nezve njodzi dzinogona kuitika dzekushandisa mushonga uyu kune ako mamiriro.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora mycophenolate,

  • udza chiremba wako uye wemishonga kana uri weergoria kune mycophenolate, mycophenolic acid, chero mimwe mishonga, kana chero chinhu chinogadzirwa mu mycophenolate kana mycophenolic acid chigadzirwa chauri kutora. Kana iwe uri kutora mycophenolate mvura, udza chiremba wako uye wemishonga kana iwe uri weergisi kune aspartame kana sorbitol. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero cheanotevera: akamiswa marasha; acyclovir (Zovirax); mamwe maantibhakitiriya akadai se amoxicillin uye clavulanic acid (Augmentin), ciprofloxacin (Cipro) ,, uye sulfamethoxazole / trimethoprim (Bactrim); azathioprine (Azasan, Imuran); cholestyramine (Prevalite); ganciclovir (Cytovene, Valcyte); mimwe mishonga inodzvinyirira immune system; isavuconazonium (Cresemba); probenecid (Probalan); proton pump inhibitors senge lansoprazole (Dexilant, Prevacid) uye pantoprazole (Protonix); rifampin (Rifadin, Rimactane, muRifamate, Rifater); telmisartan (Micardis, muTwynsta); valacyclovir (Valtrex); uye valganciclovir (Valcyte). Uyezve udza chiremba wako kana iwe uri kutora mubatanidzwa wezvose zviri zviviri norfloxacin (Noroxin) uye metronidazole (Flagyl). Mimwe mishonga yakawanda inogona zvakare kubatana ne mycophenolate, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa. Uyezve iva nechokwadi chekuudza chiremba wako kana ukarega kutora chero ipi yemishonga yako. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • kana uri kutora sevelamer (Renagel, Renvela), kana maantacid ane magnesium kana aluminium, tora iwo maawa maviri mushure mekutora mycophenolate.
  • udza chiremba wako kana iwe kana wakambove neLesch-Nyhan syndrome kana Kelley-Seegmiller syndrome (zvirwere zvakagara nhaka zvinokonzeresa huwandu hweimwe chinhu muropa, marwadzo akabatana, uye matambudziko ekufambisa uye maitiro); kupererwa neropa (yakaderera pane yakajairwa nhamba yemasero matsvuku eropa); neutropenia (isingasviki pane yakajairwa maseru machena eropa); maronda kana chero chirwere chinokanganisa dumbu rako, ura, kana kugaya system; chero mhando yekenza; kana hosha yeitsvo kana yechiropa.
  • udza chiremba wako kana iwe uchiyamwisa.
  • iwe unofanirwa kuziva kuti mycophenolate inogona kukuita iwe kukotsira, kuvhiringidzika, kuita dzungu, musoro wakareruka, kana kukonzera kusadzora kusadzora kwechikamu chemuviri. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti uyu mushonga unokubata sei.
  • hauna majekiseni pasina kutaura nachiremba wako. Kumbira chiremba wako kana iwe uchifanira kuwana mushonga wefuruu usati kana panguva yekurapwa kwako nekuti kutora mycophenolate kunogona kuwedzera njodzi yako yehutachiona.
  • kana iwe uine phenylketonuria (PKU, chinzvimbo chakagarwa nhaka umo chikafu chakasarudzika chinofanira kuteverwa kudzivirira kudzora kwepfungwa), iwe unofanirwa kuziva kuti kumiswa kwemycophenolate kune aspartame, sosi ye phenylalanine.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Kana iwe uri kutora mycophenolate piritsi, capsule, kana kumiswa (Cellcept) tora iyo yakarasika dosi nekukurumidza kana uchinge uchayeuka izvozvo. Nekudaro, kana iyo inotevera dosi iri isingasviki maawa maviri kure, svetuka iyo yakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana iwe uri kutora mycophenolate yakanonoka kuburitsa piritsi (Myfortic) tora iyo yakarasika dhizai nekukurumidza kana uchinge uchayeuka izvozvo. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Mycophenolate inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kuvimbiswa
  • kurwadziwa nemudumbu kana kuzvimba
  • kusvotwa
  • kurutsa
  • kunetseka kurara kana kuramba wakarara
  • kurwadziwa, kunyanya musana, mhasuru, kana majoini
  • musoro
  • gasi
  • kupuruzira, kurira, kana kunzwa kupisa paganda
  • kuomarara kwemhasuru kana kushaya simba

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, fonera chiremba wako nekukasira:

  • manyoka, kurwadziwa kamwe kamwe mudumbu
  • kuzvimba kwemaoko, maoko, tsoka, makumbo, kana makumbo ezasi
  • kunetseka kufema
  • kurwadziwa pachipfuva
  • mapundu
  • kuvava
  • kukurumidza kurova kwemoyo
  • dzungu
  • kufenda
  • kushaya simba
  • ganda rakachenuruka
  • kubuda ropa zvisina kujairika kana kupwanya
  • nhema uye yekumhara zvituru
  • ropa dzvuku muzvituru
  • kurutsa kweropa
  • rutsa zvinoita kunge kofi nzvimbo
  • ropa mune weti
  • yero yeganda kana maziso

Mycophenolate inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Kumiswa kweMycophenolate kunogonawo kuchengetwa mufiriji. Usaisa chando mycophenolate kuturika. Bvisa chero ipi zvayo isina kushandiswa mycophenolate kumiswa mushure memazuva makumi matanhatu.

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • kurwadziwa nemudumbu
  • kusvotwa
  • kurutsa
  • chirungurira
  • manyoka
  • fivha, huro, chironda, kukosora uye zvimwe zviratidzo zvehutachiona

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • CellCept®
  • Myfortic®
Yekupedzisira Yakagadziridzwa - 05/15/2019

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