Pomalidomide

Zvemukati

• Usati watora pomalidomide,
• Pomalidomide inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa mune ZVINOKOSHA YENYENZO kana ZVINOKOSHA ZVINONYANYA, rega kutora pomalidomide uye kufonera chiremba wako nekukurumidza:

Ngozi yeakakomba, anotyisidzira hupenyu hurema hwekuzvarwa hunokonzerwa nepomalidomide.

Kune vese varwere vanotora pomalidomide:

Pomalidomide haifanire kutorwa nevarwere vane nhumbu kana vanogona kuve nepamuviri. Pane njodzi huru yekuti pomalidomide inokonzeresa kurasikirwa nemimba kana kukonzera mwana kuzvarwa aine hurema hwekuzvara (matambudziko aripo pakuzvarwa).

Chirongwa chinonzi Pomalyst REMS^® yakagadzirirwa kuti ive nechokwadi chekuti vakadzi vane nhumbu havatore pomalidomide uye kuti vakadzi havaite nhumbu pavanotora pomalidomide. Vese varwere, kusanganisira vakadzi vasingakwanise kuve nepamuviri nevarume, vanogona kuwana pomalidomide chete kana vakanyoreswa nePomalyst REMS^®, Iva nechinodhaka kubva kuna chiremba uyo akanyoreswa nePomalyst REMS^®, uye zadza mushonga ku pharmacy iyo yakanyoreswa nePomalyst REMS^®.

Iwe unozogashira ruzivo nezve njodzi dzekutora pomalidomide uye unofanirwa kusaina pepa rekubvuma rine ruzivo unoti unonzwisisa ruzivo urwu usati wagamuchira mushonga. Iwe unozofanirwa kuona chiremba wako panguva yekurapwa kwako kuti utaure nezve mamiriro ako uye mhedzisiro yauri kusangana nayo kana kuti kuve nemimba yekuyedza sezvakakurudzirwa nechirongwa.

Udza chiremba wako kana iwe usinganzwisise zvese zvawakaudzwa nezve pomalidomide uye iyo Pomalyst REMS^® chirongwa uye kuti ungashandise sei nzira dzekudzivirira kuberekwa dzakurukurwa nachiremba wako, kana kana iwe usingafunge kuti uchakwanisa kuchengeta nguva dzakatarwa.

Usape ropa paunenge uchitora pomalidomide uye kwevhiki ina mushure mekurapwa kwako.

Usagovane pomalidomide nemumwe munhu, kunyangwe munhu ane zviratidzo zvakafanana zvaunazvo.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro RezveMishonga) paunotanga kurapwa nepomalidomide uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Unogona kushanyira webhusaiti yeFood and Drug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana http://www.celgeneriskmanagement.com kuti uwane Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekutora pomalidomide.

Kune varwere vechikadzi vanotora pomalidomide:

Kana iwe uchigona kuve nepamuviri, iwe uchafanirwa kusangana nezvimwe zvinodikanwa panguva yekurapa kwako ne pomalidomide. Unofanirwa kusangana nezvinodiwa izvi kunyangwe iwe uine tubal ligation ('machubhu akasungwa,' kuvhiyiwa kudzivirira kubata pamuviri). Unogona kuregererwa kusangana nezvinodiwa izvi chete kana usati waenda kumwedzi kwemwedzi makumi maviri nemana akateedzana uye chiremba wako achiti wapfuura kuenda kumwedzi ('shanduko yehupenyu') kana kuti wakavhiyiwa kubvisa chibereko chako uye / kana mavha maviri. Kana pasina chimwe cheizvi chiri chechokwadi kwauri, saka unofanira kusangana nezvinodiwa pazasi.

Iwe unofanirwa kushandisa maviri anogamuchirwa mafomu ekudzivirira kuberekwa kwemavhiki mana usati watanga kutora pomalidomide, panguva yekurapwa kwako, kusanganisira panguva dzachiremba paanokuudza kuti umbomira kutora pomalidomide, uye kwevhiki ina mushure mekurapwa kwako. Chiremba wako anokuudza kuti ndedzipi nzira dzekudzivirira kuberekwa dzinogamuchirwa uye anokupa ruzivo rwakanyorwa nezve kudzora kubereka. Iwe unofanirwa kushandisa aya maviri maitiro ekudzivirira kubereka nguva dzese kunze kwekunge iwe uchigona kuvimbisa kuti hauzove nehukama hwepabonde nemunhurume kwemavhiki mana usati warapwa, panguva yekurapwa kwako, panguva ipi neipi yekukanganisa pakurapa kwako, uye kwevhiki ina mushure kurapwa kwako.

Kana iwe ukasarudza kutora pomalidomide, ibasa rako kudzivirira kubata pamuviri kwemavhiki mana zvisati zvaitika, panguva, uye kwemasvondo mana mushure mekurapwa kwako. Iwe unofanirwa kunzwisisa kuti chero chimiro chekudzivirira kuberekwa chinogona kukundikana. Naizvozvo, zvakakosha kuti udzikise njodzi yekubata netsaona uchishandisa nzira mbiri dzekuzvarwa. Udza chiremba wako kana iwe usinganzwisise zvese zvawakaudzwa nezve kudzora kuberekwa kana iwe usingafunge kuti iwe unozogona kushandisa maviri maitiro ekudzivirira kubereka nguva dzese.

Iwe unofanirwa kuve nemaviri asina kunaka ekuedzwa kwepamuviri usati watanga kutora pomalidomide. Iwe zvakare unofanirwa kuongororwa kuti une nhumbu murabhoritari pane dzimwe nguva panguva yekurapwa kwako. Chiremba wako anokuudza iwe nguva uye kupi kwaunofanira kuve nemiedzo iyi.

Regedza kutora pomalidomide uye fonera chiremba wako ipapo ipapo kana iwe uchifunga kuti une nhumbu, unosuwa kuenda kumwedzi, kana iwe uchiita bonde usingashandise nzira mbiri dzekudzivirira Kana iwe ukava nepamuviri panguva yekurapa kwako kana mukati memazuva makumi matatu mushure mekurapwa kwako, chiremba wako anozobata iyo Pomalyst REMS^® chirongwa, iyo inogadzira pomalidomide, uye iyo Chikafu neDrug Administration (FDA).

Kune varwere varwere vanotora pomalidomide:

Pomalidomide iripo mumurume (urume hune hurume hunoburitswa kuburikidza nepeni panguva yegasm). Iwe unofanirwa kushandisa latex kana synthetic kondomu, kunyangwe iwe uine vasectomy (kuvhiya kunodzivirira murume kuti asakonzera nhumbu), pese paunosangana pabonde nemukadzi ane nhumbu kana anokwanisa kuve nepamuviri paunenge uchitora pomalidomide uye kwemazuva makumi maviri nemasere mushure mekurapwa kwako. Udza chiremba wako kana ukaita zvepabonde nemukadzi usingashandisi kondomu kana kana mumwe wako achifunga kuti anogona kunge aine pamuviri panguva yekurapwa kwako ne pomalidomide.

Usape urume paunenge uchitora pomalidomide uye kwevhiki ina mushure mekurapwa kwako.

Ngozi yekugwamba kweropa:

Kana iwe uri kutora pomalidomide kurapa akawanda myeloma (rudzi rwekenza yemongo wemapfupa), kune njodzi yekuti iwe unozotanga kurwara kwemoyo, sitiroko, kana kuwanda kweropa mugumbo rako (yakadzika vein thrombosis; DVT) iyo inogona kufamba neropa kuyerera kumapapu ako (pulmonary embolism, PE). Udza chiremba wako kana iwe wakambove nechirwere chemwoyo kana chirwere. Chiremba wako anogona kukuudza kuti usatora pomalidomide. Uyezve udza chiremba wako kana uchisvuta kana kushandisa fodya, kana wakarwara nemoyo kana kurohwa nesitiroko, uye kana wakambove neBP, kana kuwanda kweropa remafuta akawandisa kana mafuta, Chiremba wako anogona kupa imwe mishonga kutorwa pamwe ne pomalidomide kudzikisa njodzi iyi. Kana iwe ukasangana nechimwe cheanotevera zviratidzo paunenge uchitora pomalidomide, udza chiremba wako nekukurumidza: kutemwa nemusoro kwakanyanya; kurutsa; matambudziko ekutaura; dzungu kana kupera simba; kamwe kamwe kukwana kana kukwana kurasikirwa kwemaonero; kushaya simba kana kushama ruoko kana gumbo; kurwadziwa kwepfupa kunogona kupararira kumaoko, mutsipa, shaya, musana, kana mudumbu; mweya wekufema; kuvhiringidzika; kana kurwadziwa, kuzvimba, kana kutsvuka mune rimwe gumbo.

Taura nachiremba wako nezve njodzi dzekutora pomalidomide.

Pomalidomide inoshandiswa musanganiswa ne dexamethasone kurapa akawanda myeloma (rudzi rwekenza yemongo wemapfupa) iyo isina kuvandudzika mukati kana mukati memazuva makumi matanhatu ekurapwa nemimwe mishonga miviri, kusanganisira lenalidomide (Revlimid) uye proteasome inhibitor yakadai bortezomib (Velcade) kana carfilzomib (Kyprolis). Inoshandiswawo kurapa Kaposi's sarcoma (rudzi rwekenza runokonzeresa kuti zvishuwo zvisina kujairika kukura pazvikamu zvakasiyana zvemuviri) zvine chekuita nekuwana immunodeficiency syndrome (AIDS) mushure mekurapa zvisina kurongeka nemimwe mishonga kana kuvanhu vane Kaposi's sarcoma vasiri vane hutachiona hwehutachiona hwehutachiona hwehutachiona hweHIV. Pomalidomide iri mukirasi yemishonga inonzi immunomodulatory agents. Inoshanda nekubatsira iyo mwongo wemapfupa kugadzira maseru eropa akajairwa uye nekuuraya masero asina kujairika mumongo wepfupa.

Pomalidomide inouya sekapuleti kutora nemuromo. Inowanzo kutorwa kamwe chete zuva nezuva ne kana pasina chikafu pamazuva 1 kusvika 21 ezuva makumi maviri nemasere. Iyi 28-zuva pateni inogona kudzokororwa sezvakakurudzirwa nachiremba wako. Tora pomalidomide kwakatenderedza nguva yakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora pomalidomide chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsule akazara nemvura; usazvityora kana kuzvitsenga. Usavhure macapsule kana kuabata zvakanyanya kupfuura zvakafanira. Kana ganda rako rikasangana nemakapisi akaputswa kana hupfu, geza nzvimbo iri pachena nesipo nemvura. Kana paine chero chiputu chemukati chinopinda mumaziso ako, geza maziso ako ipapo nemvura.

Chiremba wako angangoda kumira zvachose kana kwechinguva kumisa kurapwa kwako kana kudzikisa dosi yako kana iwe ukawana mimwe mhedzisiro. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako ne pomalidomide.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora pomalidomide,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune pomalidomide, chero mimwe mishonga, kana chero chinhu chinogadzikana mune pomalidomide capsules. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: carbamazepine (Carbatrol, Tegretol, Teril, vamwe); ciprofloxacin (Cipro); fluvoxamine (Luvox); uye ketoconazole (Nizoral). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana ne pomalidomide, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kana iwe uri kugamuchira dialysis (kurapwa kwekuchenesa ropa apo itsvo dzisiri kushanda nemazvo) kana kuti kana wakambove uine chirwere chechiropa.
• usayamwisa mwana paunenge uchitora pomalidomide.
• udza chiremba wako kana ukashandisa zvigadzirwa zvefodya. Kusvuta fodya kunogona kudzora kushanda kwemushonga uyu.
• iwe unofanirwa kuziva kuti pomalidomide inogona kuita kuti unzwe dzungu kana kuvhiringidzika. Usafambisa mota, shandisa michina, kana kuita zvimwe zvinhu zvinoda kuti uve wakasvinura zvizere kusvika waziva kuti mushonga uyu unokubata sei.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Nekudaro, kana iri isingasviki maawa gumi nemaviri kusvikira yako inotevera yakarongwa dhizaini, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Pomalidomide inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kuvimbiswa
• manyoka
• kusvotwa
• kurutsa
• kurasikirwa nenzara
• uremu hunochinja
• kuzunza kusingadzoreki nhengo yemuviri
• vangadikitira zvisina kujairika kana vangadikitira usiku
• kushushikana
• ganda rakaoma
• kuzvimba kwemaoko, maoko, tsoka, makumbo, kana makumbo ezasi
• kubatana, mhasuru, kana kurwadziwa musana
• kunetseka kurara kana kuramba wakarara

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa mune ZVINOKOSHA YENYENZO kana ZVINOKOSHA ZVINONYANYA, rega kutora pomalidomide uye kufonera chiremba wako nekukurumidza:

• mapundu
• kuvava
• mikoko
• kubvaruka uye kubvisa ganda
• kuzvimba kwemaziso, kumeso, rurimi, huro, maoko, maoko, tsoka, makumbo, kana makumbo ezasi
• kunetseka kufema kana kumedza
• hoarseness
• fivha, huro, chironda, chikosoro, kana zvimwe zviratidzo zvehutachiona
• yero maziso kana ganda
• weti yakasviba
• kurwadziwa kana kusagadzikana mune yekurudyi kumusoro mudumbu nzvimbo
• kuoma, kazhinji, kana kunorwadza weti
• ganda rakachenuruka
• kuneta zvisina kujairika kana kushaya simba
• kubuda ropa zvisina kujairika kana kupwanya
• mumhino
• chiveve, kupisa, kana kugwinha maoko kana tsoka
• pfari

Pomalidomide inogona kuwedzera njodzi yekuti unozogadzira imwe kanzira. Taura nachiremba wako nezve njodzi dzekutora pomalidomide.

Pomalidomide inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana.Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Dzosera chero mishonga isingachadiwe kukhemisi yako kana mugadziri. Bvunza wako wemishonga kana iwe uine chero mibvunzo nezve kudzorera mushonga wako.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune pomalidomide.

Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Pomalyst^®