Axicabtagene Ciloleucel Jekiseni

Zvemukati

• Usati wagamuchira jekiseni reaxicabtagene ciloleucel,
• Axicabtagene ciloleucel inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, dana chiremba wako nekukurumidza:

Axicabtagene ciloleucel jekiseni inogona kukonzera yakakomba kana kutyisidzira hupenyu maitiro anonzi cytokine release syndrome (CRS). Chiremba kana mukoti anozokutarisa zvakanyatsonaka panguva yako yekumukiswa uye kweanenge mavhiki mana mushure. Udza chiremba wako kana iwe uine chirwere chekuvhiringidza kana iwe uine kana uchifunga kuti iwe unogona kunge uine chero hutachiona hutachiona izvozvi. Iwe unozopihwa mishonga maminetsi makumi matanhatu usati wanyudzwa kuti ubatsire kudzivirira maitiro kune axicabtagene ciloleucel. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge wamunyudzwa, udza chiremba wako nekukasira: fivha, kutonhora, kukurumidza kana kusarongeka kwemwoyo, kuzunza, manyoka, kuneta, kushaya simba, kunetseka kufema, kufema, kunyongana, kusvotwa, kurutsa, dzungu. , kana kuti musoro usina musoro.

Axicabtagene ciloleucel jekiseni inogona kukonzeresa kana kutyisidzira hupenyu hwepakati tsinga maitiro. Aya maitiro anogona kuitika mushure mekurapwa neaxicabtagene ciloleucel. Udza chiremba wako kana iwe wakambove nekugumburwa, sitiroko, kana kurasikirwa ndangariro. Kana ukasangana nechimwe chezviratidzo zvinotevera, udza chiremba wako nekukurumidza: kutemwa nemusoro, dzungu, kunetseka kurara kana kuramba wakarara, kusagadzikana, kuvhiringidzika, kushushikana, kuzunza kusingadzoreki kwechikamu chemuviri, kurasikirwa kwekuziva, kushungurudzika, kugwinha, kurasikirwa kuenzanisa, kunetseka kunzwisisa, kana kunetseka kutaura.

Axicabtagene ciloleucel jekiseni inongowanikwa chete kuburikidza neyakaganhurirwa chirongwa chekuparadzira nekuda kwenjodzi dzeCRS uye neurological chepfu. Unogona chete kugamuchira mishonga kubva kuna chiremba uye nzvimbo yehutano inotora chikamu muchirongwa. Kumbira chiremba wako kana iwe uine chero mibvunzo nezvechirongwa ichi.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro RezveMishonga) paunotanga kurapwa neaxicabtagene ciloleucel. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Axicabtagene ciloleucel jekiseni inoshandiswa kurapa imwe mhando yeasina-Hodgkin's lymphoma (kenza iyo inotanga mumasero machena eropa ayo anowanzo kurwisa hutachiona) iyo yadzoka kana isingateereri kune kumwe kurapwa (s) kune vanhu vakatorapwa pamwe mamwe maviri chemotherapy mishonga. Axicabtagene ciloleucel jekiseni iri mukirasi yemishonga inonzi autologous cellular immunotherapy, mhando yemishonga yakagadzirirwa kushandisa maseru kubva muropa rega murwere. Inoshanda nekukonzeresa immune system (boka remasero, zvinyama, uye nhengo zvinodzivirira muviri kubva pakurwiswa nemabhakitiriya, mavairasi, cancer maseru, nezvimwe zvinhu zvinokonzeresa chirwere) kurwisa maseru egomarara.

Axicabtagene ciloleucel jekiseni inouya sekumisa (mvura) kuiswa jekiseni (kupinda mutsinga) nachiremba kana mukoti muhofisi yechiremba kana nzvimbo yekumukisa. Iyo inowanzo kupihwa pamusoro penguva inosvika pamaminitsi makumi matatu seyadhi-yenguva imwe chete. Usati wagamuchira yako axicabtagene ciloleucel dose, chiremba wako kana mukoti achapa imwe chemotherapy mishonga kugadzirira muviri wako kune axicabtagene ciloleucel.

Pamberi pekuti dhivhizheni yeaxicabtagene ciloleucel injodzi ipiwe, sampu yemasero machena eropa ichatorwa kunzvimbo yekuunganidza maseru uchishandisa nzira inonzi leukapheresis (maitiro anobvisa masero machena eropa kubva mumuviri). Nekuti mushonga uyu unogadzirwa kubva kumaseru ako wega, unofanirwa kupihwa iwe chete. Izvo zvakakosha kuti uve nenguva uye kuti usarasikirwe yako yakarongedzwa maseru ekuunganidzwa kusarudzwa (s) kana kugamuchira yako yekurapa dosi. Iwe unofanirwa kuronga kugara padhuze nekwawakagamuchira yako axicabtagene ciloleucel kurapwa kweinokwana mavhiki mana mushure medosi yako. Anopa hutano hwako anotarisa kuti aone kana kurapwa kwako kuri kushanda uye nekukutarisa iwe kune chero zvingangoitika mhedzisiro. Taura nachiremba wako nezvekuti ungagadzirira sei leukapheresis uye zvaunotarisira panguva uye mushure mekuita.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira jekiseni reaxicabtagene ciloleucel,

• udza chiremba wako uye wemishonga kana uri weergoria kune axicabtagene ciloleucel, gentamicin, chero mimwe mishonga, dimethyl sulfoxide (DMSO), kana chero zvimwe zvinoshandiswa mujojo yeaxicabtagene ciloleucel. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: steroid senge dexamethasone, methylprednisolone (Medrol), prednisolone, uye prednisone (Rayos). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe kana wakambove nematambudziko ekufema kana mapapu, itsvo, moyo, kana chirwere chechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Iwe unozofanirwa kuve nepamuviri bvunzo usati watanga axicabtagene ciloleucel kurapwa. Kana iwe ukava nepamuviri iwe uchinge uchigamuchira axicabtagene ciloleucel jekiseni, dana chiremba wako nekukasira.
• iwe unofanirwa kuziva kuti axicabtagene ciloleucel jekiseni inogona kukutsira uye kukonzera kuvhiringidzika, kushaya simba, dzungu, pfari, uye matambudziko ekubatanidza. Usatyaire mota kana kushandisa michina kweanokwana masvondo masere mushure mekuita kwako axicabtagene ciloleucel dose.
• usape ropa, nhengo, zvinyama, kana maseru ekuisazve mushure mekugamuchira kwako injekisitagene ciloleucel jekiseni.
• bvunza nachiremba wako kuti uone kana iwe uchida kugamuchira chero majekiseni. Hauna majekiseni pasina kutaura nachiremba wako kweanenge mavhiki matanhatu usati watanga chemotherapy, panguva yako yekurapa axicabtagene ciloleucel, uye kudzamara chiremba wako akuudza kuti immune system yako yapora.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Ukatadza nguva yekutora masero ako, unofanirwa kufonera chiremba wako nenzvimbo yekuunganidza ipapo ipapo. Ukasuwa nguva yekugadzwa kuti utore yako axicabtagene ciloleucel dose, unofanira kufonera chiremba wako ipapo ipapo.

Axicabtagene ciloleucel inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kuvimbiswa
• kurwadziwa nemudumbu
• kurwadziwa shure
• kubatana kana kurwadziwa kwemhasuru
• muromo wakaoma
• kurasikirwa nenzara
• kuonda

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo kana izvo zvakanyorwa mune CHINOKOSHA CHENYENZO chikamu, dana chiremba wako nekukurumidza:

• ropa mune weti
• kubuda ropa zviri nyore kupfuura zvakajairwa
• fivha, huro, chironda, kana zvimwe zviratidzo zvehutachiona
• yakaderera weti kuwanda kana huwandu
• ganda rakachenuruka
• kuneta
• kuzvimba kwemaziso, kumeso, miromo, rurimi, huro, maoko, maoko, tsoka, makumbo, kana makumbo ezasi
• kunetseka kumedza
• mapundu
• mikoko
• kuvava

Axicabtagene ciloleucel jekiseni inogona kuwedzera njodzi yako yekuvandudza mamwe cancer. Taura nachiremba wako nezve njodzi dzekugamuchira uyu mushonga.

Axicabtagene ciloleucel inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza zvese zvakagadzwa nachiremba wako, nzvimbo yekuunganidzira masero, uye rabhoritari. Chiremba wako anogona kuraira kumwe kuongorora kwelebhu kare, panguva, uye mushure mekurapwa kwako kuti utarise mhinduro yemuviri wako kune axicabtagene ciloleucel jekiseni.

Usati waita chero bvunzo yerabhoritari, udza chiremba wako nevashandi veirabhoritari kuti urikugamuchira jekiseni reaxicabtagene ciloleucel Mushonga uyu unogona kukanganisa mhedzisiro yemamwe miedzo yemarabhoritari.

Kumbira wemishonga wako chero mibvunzo iwe unayo nezve axicabtagene ciloleucel jekiseni.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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