Alemtuzumab Jekiseni (Multiple Sclerosis)

Zvemukati

• Jekiseni reAlemtuzumab rinoshandiswa kurapa vanhu vakuru vane mhando dzakasiyana dze multiple sclerosis (MS; chirwere umo tsinga dzisingashande nemazvo uye vanhu vanogona kuona kushaya simba, kupera simba, kurasikirwa nekubatana kwetsandanyama, nematambudziko nemaonero, kutaura, uye kudzora kwedundira) vasina kuvandudza pamwe nemaviri kana anopfuura emishonga yeMMS inosanganisira:
• Usati wagamuchira alemtuzumab jekiseni,
• Alemtuzumab jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:
• Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo online pa. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Alemtuzumab jekiseni inogona kukonzera zvakakomba kana kutyisidzira hupenyu autoimmune kusagadzikana (mamiriro umo immune system inorwisa zvikamu zvine hutano zvemuviri uye inokonzeresa kurwadziwa, kuzvimba, nekukuvara), kusanganisira thrombocytopenia (yakaderera nhamba yeplatelet [rudzi rweropa reropa rinodiwa kugwamba kweropa]) nezvinetso zveitsvo. Udza chiremba wako kana uine matambudziko ekubuda ropa kana chirwere cheitsvo. Kana ukasangana nechimwe chezviratidzo zvinotevera, fonera chiremba wako nekukasira: kubuda ropa kusingawanzo, kuzvimba kwemakumbo ako kana tsoka, kukosora ropa, kubuda ropa kubva pakachekwa izvo zvakaoma kumira, kubuda ropa kunorema kana kusingaite nguva dzose, mavara paganda rako ari tsvuku, pinki, kana shava, kubuda ropa kubva pamatadza kana mumhino, ropa mune weti, kurwadziwa pachipfuva, kuderera muhuwandu weti, uye kuneta

Iwe unogona kusangana neakakomba kana anotyisidzira hupenyu infusion reaction iwe uchinge wagamuchira muyero wealemtuzumab jekiseni kana kusvika kune matatu mazuva mushure. Iwe unozogamuchira imwe neimwe dosi yemushonga munzvimbo yekurapa, uye chiremba wako achakutarisa zvakanyatsonaka panguva yekumukiswa uye mushure mekugamuchira mushonga. Izvo zvakakosha kuti iwe ugare panzvimbo yekumukisa kwemaawa angangoita maviri mushure mekunge yako infusion yapera. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge wamukirwa, udza chiremba wako nekukurumidza: fever; chills; kusvotwa; kurwadziwa nemusoro; kurutsa; mikoko; mapundu; kuvava; kutsvaira; chirungurira; dzungu; mweya wekufema; kunetseka kufema kana kumedza; kunonoka kufema; kuomesa kwehuro; kuzvimba kwemaziso, kumeso, muromo, miromo, rurimi kana huro; hoarseness; dzungu; musoro wakareruka; kufenda; nekukurumidza kana kusajairika kurova kwemoyo; kana kurwadziwa muchipfuva.

Alemtuzumab jekiseni inogona kukonzera sitiroko kana misodzi mumariti ako anopa ropa kuuropi hwako, kunyanya mukati memazuva matatu ekutanga mushure mekurapwa. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge wamukosheswa, udza chiremba wako nekukasira: kudzika kune rumwe rutivi rwechiso, kutemwa nemusoro zvakanyanya, kurwadziwa kwemutsipa, kushaya simba nekukurumidza kana kupera simba kweruoko kana gumbo, kunyanya kune rumwe rutivi rwemuviri. , kana kunetsekana kutaura, kana kunzwisisa.

Jekiseni reAlemtuzumab rinogona kuwedzera njodzi yekuti unozogadzira mamwe macancer, anosanganisira cancer yekenza, melanoma (rudzi rwegomarara reganda), uye mimwe kanzira yeropa. Iwe unofanirwa kuve nekuongororwa kweganda rako nachiremba kana uine zviratidzo zvecancer usati watanga kurapwa uye gore rimwe nerimwe mushure. Fonera chiremba wako kana iwe uine zvinotevera zviratidzo izvo zvinogona kunge zviri chiratidzo chegomarara gomarara: bundu idzva kana kuzvimba mumutsipa wako; kurwadziwa pamberi pemutsipa; kusanzwisisika kuonda; kurwadziwa kwepfupa kana kwemajoini; mapundu kana kuzvimba paganda rako, mutsipa, musoro, ura kana mudumbu; shanduko mune mamore chimiro, saizi, kana ruvara kana kubuda ropa; diki diki ine isina kukwana muganho uye zvikamu zvinoita sezvitsvuku, chena, bhuruu kana bhuruu-dema; huni kana rimwe izwi rinoshanduka risingapfuuri; kunetseka kumedza kana kufema; kana kukosora.

Nekuda kwenjodzi nemushonga uyu, alemtuzumab jekiseni inowanikwa chete kuburikidza neyakaganhurirwa nzira yekugovera. Chirongwa chinonzi chirongwa chinonzi Lemtrada Risk Evaluation uye Mitigation Strategy (REMS) Chirongwa. Kumbira chiremba wako kana iwe uine chero mibvunzo nezvekuti uchawana sei mushonga wako.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira mimwe bvunzo kuti utarise mhinduro yemuviri wako kune alemtuzumab jekiseni usati uye panguva yekurapwa kwako uye kwemakore mana mushure mekunge wagamuchira yako yekupedzisira dosi.

Taura nachiremba wako nezve njodzi dzekugamuchira jekiseni realemtuzumab.

Jekiseni reAlemtuzumab rinoshandiswa kurapa vanhu vakuru vane mhando dzakasiyana dze multiple sclerosis (MS; chirwere umo tsinga dzisingashande nemazvo uye vanhu vanogona kuona kushaya simba, kupera simba, kurasikirwa nekubatana kwetsandanyama, nematambudziko nemaonero, kutaura, uye kudzora kwedundira) vasina kuvandudza pamwe nemaviri kana anopfuura emishonga yeMMS inosanganisira:

• kudzokerazve-kuregedza mafomu (kosi yechirwere uko zviratidzo zvinopisa nguva nenguva) kana
• yechipiri inofambira mberi mafomu (kosi yechirwere uko kudzokazve kunoitika kazhinji).

Alemtuzumab iri mukirasi yemishonga inonzi monoclonal antibodies. Inoshanda nekudzora kuita kwema immune maseru anogona kukonzera kukuvara kwetsinga.

Alemtuzumab inowanikwawo sejekiseni (Campath) iyo inoshandiswa kurapa chirwere cheLymphocytic leukemia (gomarara rinokura zvishoma nezvishoma iro rakawandisa mumuviri weropa jena reropa. Iyi monograph inopa chete ruzivo nezve alemtuzumab jekiseni (Lemtrada) ye multiple sclerosis. Kana iwe uri kugamuchira alemtuzumab yechirwere cheLymphocytic leukemia, verenga monograph yakanzi Alemtuzumab Injection (Chronic Lymphocytic Leukemia).

Alemtuzumab jekiseni inouya semhinduro (mvura) kujowa mukati (mukati mutsinga) anopfuura maawa mana nachiremba kana mukoti muchipatara kana hofisi yekurapa. Inowanzo kupihwa kamwe zuva nezuva kwemazuva mashanu kwekutanga kurapwa kutenderera. Yechipiri yekurapa kutenderera inowanzo kupihwa kamwe zuva nezuva kwemazuva matatu, mwedzi gumi nemaviri mushure mekutanga kurapwa kutenderera. Chiremba wako anogona kupa imwezve yekurapa kutenderera kwemazuva matatu kana gumi nemaviri mwedzi mushure mekurapwa kwekutanga.

Alemtuzumab jekiseni inobatsira kudzora akawanda sclerosis, asi hairape.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira alemtuzumab jekiseni,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune alemtuzumab, chero mimwe mishonga, kana chero chinhu chinosanganiswa mujojo yealelemtuzumab. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera zvinovaka muviri, zvauri kutora kana kuronga kutora. Ive neshuwa yekutaura zvinotevera: alemtuzumab (Campath; zita rechiratidzo chechigadzirwa chinoshandiswa kurapa leukemia); mishonga yekenza; kana immunosuppressive mishonga yakadai se cyclosporine (Gengraf, Neoral, Sandimmune), mycophenolate (Cellcept), prednisone, uye tacrolimus (Astagraf, Envarsus, Prograf). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana uine hutachiona kana hutachiona hwehutachiona hwehutachiona (HIV). Chiremba wako angangokuudza kuti usatore alemtuzumab jekiseni.
• udza chiremba wako kana iwe wakambove nechirwere chetibhii (TB; chirwere chakakomba chinokanganisa mapapu uye dzimwe nguva zvimwe zvikamu zvemuviri), herpes zoster (shingles; rash inogona kuitika kune vanhu vane chickenpox munguva yakapfuura) , genital herpes (herpes virus hutachiona hunokonzeresa maronda kutenderedza nhengo dzesikarudzi uye rectum nguva nenguva), varicella (chickenpox), chirwere chechiropa chinosanganisira hepatitis B kana hepatitis C, kana thyroid, moyo, mapapu, kana chirwere chenduru.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe uri munhukadzi, iwe uchafanirwa kutora nhumbu yekubata usati watanga kurapwa uye kushandisa kuberekwa kudzora panguva yekurapa kwako uye kwemwedzi mina mushure meyako yekupedzisira dosi. Taura nachiremba wako nezvemhando dzekudzivirira kuberekwa dzaungashandisa kudzivirira kubata pamuviri panguva ino. Kana iwe ukava nepamuviri iwe uchinge uchigamuchira alemtuzumab jekiseni, danaidza chiremba wako nekukasira. Alemtuzumab inogona kukuvadza fetus.
• bvunza nachiremba wako kuti uone kana iwe uchida kugamuchira chero majekiseni usati wagamuchira alemtuzumab. Udza chiremba wako kana iwe wakagamuchira mushonga mukati memavhiki matanhatu apfuura. Hauna majekiseni pasina kutaura nachiremba wako panguva yekurapwa kwako.

Dzivisa chikafu chinotevera chingakonzere hutachiona kweinenge mwedzi usati watanga kugamuchira alemtuzumab uye panguva yekurapwa kwako: nyama yekudyira, zvigadzirwa zvemukaka zvakagadzirwa nemukaka usina kunamwa, chizi dzakapfava, kana nyama isina kubikwa, hove dzegungwa, kana huku.

Alemtuzumab jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kunetseka kurara kana kukotsira
• kurwadziwa mumakumbo, maoko, zvigunwe, uye maoko
• musana, kubatana, kana kurwadziwa kwemutsipa
• kurira, kubaya, kutonhora, kupisa, kana kuita chiveve paganda
• yakatsvuka, inocheka, kana ganda rine ganda
• chirungurira
• kuzvimba kwemhino nehuro

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kufema kufema, kurwadziwa pachipfuva kana kuomesa, kukosora, kukosora ropa, kana kufema
• fivha, kutonhora, manyoka, kusvotwa, kurutsa, kutemwa nemusoro, kurwadza kwemajoini kana kwemhasuru, kuomarara kwemutsipa, kunetseka kufamba,
• kupwanya kana kubuda ropa zviri nyore, ropa mumuti kana weti, kubuda mumhino, kurutsa kweropa, kana kurwadza uye / kana kuzvimba majoini
• kudikitira zvakanyanya, ziso kuzvimba, kuonda, kutya, kana kukurumidza kurova kwemoyo
• kusanzwisisika kurema kuwedzera, kuneta, kunzwa kutonhora, kana kupatirwa
• kuora mwoyo
• kufunga nezvekuzvikuvadza kana kuzviuraya kana kuronga kana kuyedza kuzviita
• maronda ekubereka, kunzwa kwepini uye tsono, kana kuputika panhengo yemurume kana munzvimbo yemukadzi
• maronda anotonhora kana mabhanduru efivhiri mukati kana kutenderedza muromo
• kuputika kunorwadza kune rumwe rutivi rwechiso kana muviri, uine blister, kurwadziwa, kuchenesa, kana kugwinha munzvimbo yekumhanyisa
• (mune vakadzi) kunhuhwirira kwemukadzi, chena kana yero yenyuchi kubuda (kungave kune bundu kana kutaridzika sekottage chizi), kana kusangana nekutsi kwemukadzi
• machena machena parurimi kana matama emukati
• kurwadziwa mudumbu kana unyoro, fivha, kusvotwa, kana kurutsa
• kusvotwa, kurutsa, kurwadziwa nemudumbu, kuneta zvakanyanya, kurasikirwa nechido, maziso eyero kana ganda, kuneta zvakanyanya, weti yakasviba, kana kubuda ropa kana kupwanya zviri nyore kupfuura zvakajairwa
• kushaya simba kune rumwe rutivi rwemuviri rwunowedzera kupfuura nguva; kusindimara kwemaoko kana makumbo; shanduko mukufunga kwako, ndangariro, kufamba, kuenzanisa, kutaura, kuona, kana simba rinogara mazuva mazhinji; musoro; pfari; kuvhiringidzika; kana hunhu hunoshanduka
• fivha, kuzvimba gland, kuputika, kubatika, shanduko mukufunga kana kusvinura, kana kutsva kana kuwedzera kusagadzikana kana kunetsekana kufamba

Alemtuzumab jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo online pa. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

• musoro
• mapundu
• dzungu

Bvunza wako wemishonga chero mibvunzo iwe unayo nezve alemtuzumab jekiseni.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Lemtrada^®