Methotrexate jekiseni

Zvemukati

• Usati wagamuchira jekiseni remethotrexate,
• Methotrexate inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Methotrexate inogona kukonzera zvakakomba, kutyisidzira hupenyu mhedzisiro. Iwe unofanirwa chete kugamuchira methotrexate jekiseni yekurapa gwara rinotyisidzira hupenyu, kana mamwe mamiriro ezvinhu akaomarara uye asingakwanise kurapwa nemimwe mishonga. Taura nachiremba wako nezve njodzi dzekugamuchira methotrexate jekiseni kune ako mamiriro.

Udza chiremba wako kana iwe kana wakambove uine yakawandisa mvura mudumbu rako nzvimbo kana munzvimbo yakatenderedza mapapu ako uye kana iwe kana wakambove uine chirwere cheitsvo. Uyezve udza chiremba wako kana uri kutora nonsteroidal anti-inflammatory drug (NSAIDs) senge aspirin, choline magnesium trisalicylate (Tricosal, Trilisate), ibuprofen (Advil, Motrin), magnesium salicylate (Doan's), naproxen (Aleve, Naprosyn), kana salsalate. Aya mamiriro uye mishonga inogona kuwedzera njodzi yekuti iwe uchave wakakomba mhedzisiro mhedzisiro yemethotrexate. Chiremba wako anozokutarisa zvakanyatsonaka uye angangoda kukupa dosi yakaderera yemethotrexate kana kumisa kurapwa kwako ne methotrexate.

Methotrexate inogona kukonzera kuderera kwenhamba yemasero eropa akagadzirwa nefupa rako. Udza chiremba wako kana iwe wakambove kana wakambove nenhamba yakaderera yechero mhando yemasero eropa kana chero rimwe dambudziko nemasero ako eropa. Fonera chiremba wako nekukasira kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona kupwanya kusingawanzo kana kubuda ropa; kuneta zvisina kujairika kana kushaya simba; ganda rakachenuruka; kana kufema kwekufema.

Methotrexate inogona kukonzera kukuvara kwechiropa, kunyanya kana ichitorwa kwenguva yakareba. Udza chiremba wako kana iwe uchinwa kana kuti wakambonwa doro rakawanda kana kuti kana iwe kana wakambove nechirwere chechiropa. Chiremba wako anogona kunge asingade kuti ugamuchire jekiseni remethotrexate kunze kwekunge uine kenza inotyisidzira hupenyu nekuti pane njodzi yakakura yekuti unozokuvara chiropa. Iyo njodzi yekuti iwe uchave nekukuvara kwechiropa inogona zvakare kuve yakakwira kana iwe wakura, kufutisa, kana uine chirwere cheshuga. Kumbira chiremba wako nezve kushandiswa kwakachengeteka kwezvinwiwa apo iwe uri kugamuchira jekiseni remethotrexate. Udza chiremba wako kana uri kutora chero ipi yemishonga inotevera: acitretin (Soriatane), azathioprine (Imuran), isotretinoin (Accutane), sulfasalazine (Azulfidine), kana tretinoin (Vesanoid). Fonera chiremba wako nekukasira kana iwe uchinge waona chero cheanotevera zviratidzo: kusvotwa, kuneta zvakanyanya, kushaya simba, kurasikirwa nenzara, kurwadziwa munzvimbo yepamusoro yekurudyi yemudumbu, yero yeganda kana maziso, kana zviratidzo zvakaita sefuru. Chiremba wako anogona kuraira chiropa biopsies (kubviswa kwechikamu chidiki chechiropa tishu kuti chiongororwe murabhoritari) usati uye panguva yekurapa kwako ne methotrexate.

Methotrexate inogona kukonzera kukuvara kwemapapu. Udza chiremba wako kana iwe wakambove kana uine chirwere chemapapu. Fonera chiremba wako nekukasira kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchingaona

Methotrexate inogona kukanganisa kukuvara kwemuromo wako, mudumbu kana ura. Udza chiremba wako kana wakambove nemaronda emudumbu kana ulcerative colitis (chirwere chinokonzeresa kuzvimba uye maronda mumutsara wekoloni [ura hukuru] uye rectum). Shevedza chiremba wako nekukasira kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchita.

Kushandisa methotrexate kunogona kuwedzera njodzi yekuti unozokura lymphoma (kenza inotanga mumasero ezvirwere zvemuviri). Kana iwe ukaita lymphoma, inogona kuenda isina kurapwa paunomira kutora methotrexate, kana inogona kuda kurapwa nekemotherapy.

Kana iwe uri kutora methotrexate kurapa cancer, iwe unogona kukudziridza zvimwe zvinetso zvinogona kuve zvakakomba kana kutyisidzira hupenyu sezvo methotrexate inoshanda kuparadza gomarara maseru. Chiremba wako anozokutarisa zvakanyatsonaka uye obata matambudziko aya kana akaitika.

Methotrexate inogona kukonzera zvakakomba kana kutyisidzira hupenyu kuita kweganda. Kana iwe ukasangana nechimwe cheanotevera zviratidzo, fonera chiremba wako nekukasira: fever, rash, blisters, kana peeling ganda.

Methotrexate inogona kudzora mashandiro e immune system yako, uye unogona kukura hutachiona hwakakomba. Udza chiremba wako kana iwe uine chero hutachiona hutachiona uye kana iwe uine kana wakambove nechero mamiriro anobata immune system yako. Chiremba wako anogona kukuudza kuti haufanire kugamuchira methotrexate kunze kwekunge uine kenza inotyisa. Kana iwe ukaona zviratidzo zvehutachiona senge huro inorwadza, chikosoro, fivha, kana kutonhora, danaidza chiremba wako nekukasira.

Kana iwe ukatambira methotrexate iwe paunenge uchirapwa ne radiation radiation yekenza, methotrexate inogona kuwedzera njodzi yekuti kurapwa kwe radiation kuchakanganisa ganda rako, mapfupa, kana zvimwe zvikamu zvemuviri wako.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira kumwe kuongorora kwerebhu kare, panguva, uye mushure mekurapwa kwako kuti utarise mhinduro yemuviri wako kune methotrexate uye nekurapa mhedzisiro isati yaoma.

Udza chiremba wako kana iwe kana mumwe wako ane pamuviri kana kuronga kuva nepamuviri. Kana iwe uri munhukadzi, iwe uchafanirwa kutora nhumbu bvunzo usati wagamuchira methotrexate. Shandisa nzira yakavimbika yekudzivirira kuberekwa kuitira kuti iwe kana mumwe wako musazove nepamuviri panguva kana pfupi mushure mekurapwa. Kana iwe uri murume, iwe neako mukadzi mukadzi munofanira kuramba muchishandisa kuberekwa kwemwedzi mitatu mushure mekumira kushandisa methotrexate. Kana iwe uri munhukadzi, iwe unofanirwa kuenderera mberi nekushandisa kubata pamuviri kusvikira waenda kumwedzi kumwe kwakatanga mushure mekumira kushandisa methotrexate. Kana iwe kana mumwe wako ukava nepamuviri, danaidza chiremba wako nekukurumidza. Methotrexate inogona kukuvadza kana kufa kune fetus.

Methotrexate jekiseni rinoshandiswa roga kana musanganiswa nemimwe mishonga yekurapa gestational trophoblastic tumors (rudzi rwebundu rinoumba mukati mechibereko chemukadzi paanenge aine nhumbu), gomarara repazamu, gomarara remapapu, mamwe kanzira yemusoro nemutsipa; mamwe marudzi eleukemia (kenza yemasero machena eropa), kusanganisira acute lymphocytic leukemia (ALL) uye meningeal leukemia (kenza iri muchiuno chepelinha neuropi); mamwe marudzi asiri eHodgkin's lymphoma (mhando dzekenza dzinotanga mune imwe mhando yemasero machena eropa ayo anowanzo kurwisa hutachiona); akachekwa T-cell lymphoma (CTCL, boka remakenza emasoja ekudzivirira muviri anotanga kuoneka seganda mapundu); uye osteosarcoma (kenza inoumba mumapfupa) mushure mekuvhiyiwa kubvisa bundu. Methotrexate jekiseni inoshandiswawo kurapa zvakanyanya psoriasis (chirwere cheganda umo mutsvuku, makanda makanda anoumbwa pane dzimwe nzvimbo dzemuviri) asingakwanise kudzorwa nemamwe marapirwo. Methotrexate jekiseni inoshandiswa zvakare pamwe nekuzorora, kurapwa kwemuviri uye dzimwe nguva mimwe mishonga yekurapa yakanyanya inoshanda rheumatoid arthritis (RA; mamiriro ayo muviri unorwisa majoini ayo, zvichikonzera kurwadziwa, kuzvimba, uye kurasikirwa kwebasa) risingakwanise kudzorwa ne mimwe mishonga. Methotrexate iri mukirasi yemishonga inonzi antimetabolites. Methotrexate inobata cancer nekudzora kukura kwemasero ekenza. Methotrexate inobata psoriasis nekudzora kukura kwemasero eganda kumisa zviyero kubva pakuumbwa. Methotrexate inogona kurapa rheumatoid arthritis nekuderedza chiitiko chemuviri wemuviri.

Methotrexate jekiseni inouya sehupfu hunofanira kusanganiswa nemvura kuti ijojowe mukati metsinga (mumhasuru), mukati mehasha (kupinda mutsinga), mukati-arterially (kupinda mutsinga), kana mukati mekunze (munzvimbo inozadzwa nemvura inoyerera yemuzongoza ). Kureba kwekurapa kunoenderana nemhando dzemishonga yauri kutora, kuti muviri wako unopindura sei kwavari, uye nemhando yekenza kana mamiriro aunayo.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Methotrexate dzimwe nguva inoshandiswa pamwe chete nemimwe mishonga yekurapa gomarara redundira. Iyo zvakare dzimwe nguva inoshandiswa kurapa chirwere cheCrohn (mamiriro umo immune system inorwisa iyo lining yeiyo nzira yekugaya, ichikonzera marwadzo, manyoka, kuonda uye fever) uye zvimwe zvirwere zvemuviri (mamiriro anokura apo immune system inorwisa maseru ane hutano mukati muviri nekukanganisa). Kumbira chiremba wako nezve njodzi dzekushandisa mushonga uyu kune ako mamiriro.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira jekiseni remethotrexate,

• udza chiremba wako uye wemishonga kana uri weergoria kune methotrexate, chero mimwe mishonga, kana chero chinhu chinosanganiswa mujekiseni re methotrexate. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa mune CHINOKOSHA CHENYENZO chikamu uye chero cheanotevera: mamwe maantibhakitiriya senge chloramphenicol (Chloramycetin), penicillin, uye tetracylcines; folic acid (inowanikwa yoga kana sechinhu chinowanikwa mune mamwe mavitamini); mimwe mishonga yerheumatoid arthritis; phenytoin (Dilantin); probenecid (Benemid); proton pump inhibitors (PPIs) senge esomeprazole (Nexium), omeprazole (Prilosec, Prilosec OTC, Zegerid), pantoprazole (Protonix); sulfonamides senge co-trimoxazole (Bactrim, Septra), sulfadiazine, sulfamethizole (Urobiotic), uye sulfisoxazole (Gantrisin); uye theophylline (Theochron, Theolair). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe wakambove kana nechero ipi yemamiriro ezvinhu ataurwa muchikamu CHINOKOSHA CHENYENZO kana yakaderera folate muropa rako.
• usayamwisa paunenge uchigamuchira jekiseni remethotrexate.
• iwe unofanirwa kuziva kuti methotrexate inogona kukonzera dzungu kana kukuita kuti unzwe kukotsira. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti uyu mushonga unokubata sei.
• ronga kudzivirira kudzivirirwa zvisina kukodzera kana kwenguva refu kune chezuva kana ultraviolet mwenje (kuchenesa mibhedha nemarambi ezuva) uye kupfeka mbatya dzekudzivirira, magirazi ezuva, uye sunscreen. Methotrexate inogona kuita kuti ganda rako ribate chiedza chezuva kana ultraviolet light. Kana iwe uine psoriasis, maronda ako anogona kuwedzera kana iwe ukaisa pachena ganda rako kune chezuva iwe uri kugamuchira methotrexate.
• hauna majekiseni panguva yekurapwa kwako ne methotrexate usinga taure nachiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Methotrexate inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kubatana kana kurwadziwa kwemhasuru
• maziso akatsvuka
• matadza kuzvimba
• kurasikirwa nevhudzi

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kurutsa
• kusaona zvakanaka kana kurasikirwa kamwe kwemaonero
• pakarepo fivhiri, kutemwa nemusoro kwakakomba, uye nemitsipa yakaoma
• pfari
• kuvhiringidzika kana kurasikirwa mundangariro
• kushaya simba kana kunetsekana kufamba rimwe kana mativi ese emuviri
• kunetseka kufamba kana kusagadzikana kufamba
• kurasikirwa kwekuziva
• kutadza kutaura
• kuderera kwekuita weti
• kuzvimba kwechiso, maoko, maoko, tsoka, makumbo, kana makumbo ezasi
• mikoko
• kuvava
• kuputika kweganda
• kunetseka kufema kana kumedza

Methotrexate inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• maronda mumuromo nehuro
• kurwadziwa pahuro, kutonhora, kupisa muviri, kuora kuri kuramba kuchiita uye kuzara, kana zvimwe zviratidzo zvehutachiona
• kupwanya kusingawanzo kana kubuda ropa
• nhema uye mira kana zvituru zvine ropa
• kurutsa kweropa
• yakarutsa zvinhu zvinoita kunge kofi nzvimbo

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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