Monoclonal antibodies: zvaari uye nei vachibatsira kurapa zvirwere

Zvemukati

• Mienzaniso yea monoclonal antibodies
• 1. Trastuzumab
• 2. Denosumab
• 3. Obinutuzumab
• 4. Ustequinumab
• 5. Pertuzumab
• Maitiro Ekutora Monoclonal Antibodies

MaMonoclonal antibodies mapuroteni anoshandiswa nema immune system kuti aone uye kutapudza miviri yekune dzimwe nyika, ayo anogona kunge ari mabhakitiriya, mavairasi kana kunyange tumarara maseru. Aya mapuroteni akajeka, sezvo achiziva chakanangwa, icho chinonzi antigen, chinove chiripo mumasero ekunze kune muviri. Nzwisisa mashandiro anoita immune system.

MaMonoclonal antibodies, senge denosumab, obinutuzumab kana ustequinumab, semuenzaniso, anogadzirwa murabhoritari, kazhinji yakafanana neaya anowanikwa mumuviri wemunhu, izvo zvinobatsira muviri kurwisa zvimwe zvirwere. Nekudaro, zvinoenderana neye monoclonal antibody yakashandiswa, mishonga iyi inogona kushandiswa kurapa zvimwe zvirwere zvakakomba senge osteoporosis, leukemia, plaque psoriasis kana mamwe marudzi ekenza, senge kenza yemazamu kana pfupa, semuenzaniso.

Mienzaniso yea monoclonal antibodies

Mimwe mienzaniso yea monoclonal antibodies anosanganisira:

1. Trastuzumab

Iyi monoclonal antibody, yakashambadzirwa saHerceptin, yakagadzirwa neinjiniya, uye inonyatsorwisa puroteni iriko kune vanhu vane mamwe kanzira yemazamu nemudumbu. Nekudaro, uyu mushonga unoratidzirwa pakurapa gomarara repazamu mune yekutanga nhanho kana nemastastasis uye gastric cancer mune yakakwira nhanho.

2. Denosumab

Inotengeswa seProlia kana Xgeva, ine murondedzero wayo monoclonal IgG2 antibody, inopesana nekuita kweprotein yakati inoita mapfupa akasimba, ichideredza mikana yekutyoka. Nekudaro, Denosumab inoratidzirwa yekurapa kwemapfupa kurasikirwa, osteoporosis, gomarara repfupa kana kenza mune yakakwira nhanho nemapfupa metastases (ayo akapararira kumapfupa).

3. Obinutuzumab

Iyo inozivikanwa zvakare nekutengesa seGazyva, ine mune ayo masosi antibodies ayo anoziva uye anonamatira kune CD20 protein, inowanikwa pamusoro pemasero machena eropa kana maL lymphocyte B. Saka, obinutuzumab inoratidzirwa pakurapa chirwere chisingaperi che lymphocytic leukemia, sezvazviri inokwanisa kumisa kusanzwisisika kukura kwemasero machena eropa anokonzera chirwere ichi.

4. Ustequinumab

Mushonga uyu unogona zvakare kuzivikanwa nekutengesa saStelara uye unoumbwa neyemunhu IgG1 monoclonal antibody, iyo inodzivirira chaiwo mapuroteni ayo anokonzera kukonzera psoriasis. Nekudaro, uyu mushonga unoratidzwa pakurapa kwepaki psoriasis.

5. Pertuzumab

Iyo inozivikanwawo sePerjeta, inoumbwa nema monoclonal antibodies anosunga kune yemunhu epidermal kukura factor 2 receptor, inowanikwa mune mamwe maseru egomarara, ichidzora kana kumisa kukura kwavo. Nekudaro, Perjeta inoratidzirwa yekurapa kenza yemazamu.

Maitiro Ekutora Monoclonal Antibodies

Mishonga ine maMonoclonal Antibodies inofanirwa kungotorwa pasi pezano rekurapa, serudzi rweantibody kuti ishandiswe uye madosi anokurudzirwa anoenderana nedambudziko rinofanira kurapwa nekuomarara kwaro.

Muzviitiko zvakawanda, mishonga iyi inoshandiswa pakurapa gomarara, sezvo iri mishonga inorwisa hutachiona inofanirwa kushandiswa zvinoenderana nemirayiridzo yakapihwa nachiremba uye inoda kupihwa muzvipatara kana makiriniki.