Bvunza iyo Nyanzvi: Kugadzirisa Yako Idiopathic Thrombocytopenic Purpura Kurapa

Zvemukati

• Ndeapi mamwe marapirwo akajairwa eITP?
• Ndichaziva sei kuti kurapwa kwangu kuri kushanda? Zvichada kuyedzwa here?
• Pane here mhedzisiro yekurapa ITP? Ngozi?
• Ndingaite sei kuti ndive nemhedzisiro mhedzisiro yekurapwa?
• Ndichaenda kangani kwachiremba kuti ndinoongororwa? Zvakakosha zvakadii kuenderera kuyedzwa?
• Inogona here ITP kuwana zvirinani pachayo?
• Chii chinoitika kana ndikamira kutora kurapwa?
• Kurapwa kwangu kweITP kuchachinja nekufamba kwenguva here? Ini ndichave ndiri pakurapwa kwehupenyu hwangu hwese here?

Ndeapi mamwe marapirwo akajairwa eITP?

Kune akatiwandei marudzi emishonga yekurapa yeITP kukwidza maplatelet kuverenga uye kudzikisa njodzi yekubuda ropa kwakanyanya.

Steroid. Steroid inowanzo shandiswa sekurapa kwekutanga-mutsara. Ivo vanodzvinyirira immune immune, iyo inogona kukanganisa autoimmune platelet kuparadzwa.

Intravenous immunoglobulin (IVIG). IVIG inopindirana ne-antibody-yakavharwa platelet inosunga kune avo vanogamuchira masero anovaparadza. IVIG inogona kushanda zvakanyanya, asi mhinduro dzinowanzo gara kwenguva pfupi.

Anti-CD20 monoclonal antibodies (mAbs). Izvi zvinoparadza masero eB, masero ezvirwere zvemuviri anoita maantiplatelet antibodies.

Thrombopoietin receptor agonists (TPO-RA). Izvi zvinoteedzera zvinoitwa nechero kukura kwechisimba thrombopoietin uye kukurudzira mwongo wepfupa kuwedzeredza maplatelet.

SYK inhibitor. Mushonga uyu unovhiringidza yakakosha inoshanda nzira mu macrophages, iwo maseru ayo ari epamoyo saiti yekuparadzwa kweplatelet.

Splenectomy. Uku kuvhiya kubvisa chirwatata kunobvisa iyo yekutanga anatomical saiti yekuparadzwa kweplatelet. Zvinogona kutungamira mukuregererwa kwenguva refu mune vamwe vanhu.

Ndichaziva sei kuti kurapwa kwangu kuri kushanda? Zvichada kuyedzwa here?

Chinangwa chekurapwa kweITP kudzora njodzi yekubuda ropa kwakakomba nekuuraya nekuchengeta maplatelet kuverenga munzvimbo yakachengeteka. Iyo yakaderera iyo platelet kuverenga, iyo yakanyanya njodzi yekubuda ropa. Zvisinei, zvimwe zvinhu zvinogona kukanganisa njodzi yako yekubuda ropa, senge zera rako, danho rebasa, uye mimwe mishonga yauri kutora.

Chiyero chakazara cheropa (CBC) chinoshandiswa kuona kuwanda kweplatelet kuverenga uye kuona mhinduro pakurapwa.

Pane here mhedzisiro yekurapa ITP? Ngozi?

Sezvakaita chero chirwere chisingaperi, kune njodzi, mhedzisiro, uye mabhenefiti ekurapa ITP. Semuenzaniso, kudzvinyirira immune immune kunogona kushanda zvakanaka kurapa autoimmune zvirwere. Asi izvi zvinowedzerawo njodzi yako yekuwana hutachiona.

Sezvo kune akawanda anoshanda ekurapa kweITP, kurukura zvese zvaunogona kuita nachiremba wako. Zvakare, iwe unogara uine sarudzo yekuchinjira kune imwe mhando yekurapa kana iwe uchinge uchinge uchinge usinga shivirike mhedzisiro kubva kune yako yazvino kurapwa.

Ndingaite sei kuti ndive nemhedzisiro mhedzisiro yekurapwa?

Chishandiso chakakosha pakuronga mhedzisiro yekurapa kutaurirana nachiremba wako. Semuenzaniso, kana ndikaziva mumwe wevarwere vangu ari kunetsemara nemusoro neIVIG kana zvakanyanya kurema kuwana uye kusanduka kwemanzwiro kubva kumaSteroids, mazano angu ekurapa achachinja. Ndichatsvaga dzimwe nzira dzinorapika dzekurapa.

Mhedzisiro yemamwe marapirwo inowanzo kupindura kune inotsigira mishonga yekurapa. Zvakare, madosi anogona kuchinjika zvichienderana nemhedzisiro.

Ndichaenda kangani kwachiremba kuti ndinoongororwa? Zvakakosha zvakadii kuenderera kuyedzwa?

Hukama huri kuenderera mberi neyehemmatologist ane ruzivo hwakakosha kune chero munhu ane ITP. Kuwanda kwekuyedza kuchasiyana zvichienderana nekuti uri kubuda ropa zvakanyanya here kana kuti maplatelet ako akaderera zvakanyanya.

Kamwe kurapwa kutsva kwatanga, kuyedzwa kunogona kuitwa zuva nezuva kana vhiki. Kana maplatelet ari munzvimbo yakachengeteka nekuda kwekuregererwa (p.

Inogona here ITP kuwana zvirinani pachayo?

Kune vanhu vakuru vane ITP, kuve nekuregererwa kwepasipo pasina kurapwa hakuwanzo (anenge mapfumbamwe muzana maererano). Zvinowanzoitika kuti uwane kuregererwa kwakasimba mushure mekurapa kwakanaka.

Kumwe kurapwa kunopihwa kwenguva yakatarwa netarisiro yekuwana yakareba-isina kurapwa nguva, imwe neimwe iine mhinduro dzakasiyana. Izvi zvinosanganisira steroid, IVIG, mAbs, uye splenectomy. Mamwe marapirwo anoenderera mberi achigadziriswa kuchengetedza maplatelet munzvimbo yakachengeteka. Izvi zvinosanganisira TPO-RAs, SYK inhibitors, uye chisingaperi immunosuppressants.

Chii chinoitika kana ndikamira kutora kurapwa?

Kumisa kurapwa kunogona kukonzera kudonha kamwe kamwe mumaplatelet count yako. Inogona zvakare kutungamira kune yakanyanya njodzi yekubuda ropa kwakakomba kana kuuraya. Kukurumidza uye kuderera kweplatelet kunogona kudonha mushure mekumisa kurapwa kunosiyana pakati pevanhu vane ITP.

Pane njodzi shoma mukumisa kurapwa kana yako platelet kuverenga iri munzvimbo yakachengeteka. Mazhinji epamusoro-dose steroid anoda kubatwa zvishoma nezvishoma pamusoro penguva kudzivirira adrenal dambudziko uye kubvumira muviri kugadzirisa.

Ehe, zvakakosha kuti utaure kazhinji nachiremba wako nezve zvaunonetseka uye zvaunoda.

Kurapwa kwangu kweITP kuchachinja nekufamba kwenguva here? Ini ndichave ndiri pakurapwa kwehupenyu hwangu hwese here?

Sezvo mukuru ITP ichigara chiri chirwere chisingaperi, vanhu vanorarama nemamiriro acho vanowanzo tenderera kuburikidza nemhando dzakasiyana dzekurapa muhupenyu hwavo hwese.

Dr. Ivy Altomare mumwe purofesa wezvekurapa kuDuke University Medical Center. Ane hunyanzvi hwekiriniki mune dzakasiyana siyana hematological uye oncological mamiriro uye kuongororwa uye anga achiitisa zvekurapa uye zvehutano mabasa mumunda weITP kweanopfuura makore gumi. Iye ndiye anokudzwa mugashiri wevose veChikoro cheVadiki uye cheVakuru veVadzidzisi veVadzidzisi veDhipatimendi kuDuke University uye anofarira zvakanyanya dzidzo yezvokurapa kune vese varwere nevarapi.