Yemahara Mwenje Maketani

Zvemukati

• Chii chinonzi yemahara mwenje emaketeni bvunzo?
• Chii chinoshandiswa?
• Sei ini ndichida yemahara mwenje macheni bvunzo?
• Chii chinoitika panguva yemahara emwenje macheni bvunzo?
• Ndichafanira here kuita chero chinhu kugadzirira bvunzo?
• Kune here chero njodzi kune yemahara mwenje macheni bvunzo?
• Zvinorevei mhedzisiro yacho?
• Pane chimwe chinhu here chandinofanira kuziva nezve yemahara mwenje macheni bvunzo?
• Zvinyorwa

Chii chinonzi yemahara mwenje emaketeni bvunzo?

Maketani akareruka mapuroteni akagadzirwa nemasero eplasma, mhando yesero reropa chena. Masero ePlasma anogadzirawo immunoglobulins (antibodies). Immunoglobulins anobatsira kuchengetedza muviri kurwara nezvirwere. Immunoglobulins inoumbwa kana cheni dzakareruka dzakabatana nemaketani anorema, imwe mhando yeprotein. Kana macheni machena achibatana nemaketani anorema, ivo vanozivikanwa se akasungwa macheni macheni.

Kazhinji, masero eplasma anoita mashoma ekuwedzera mwenje macheni asingasunge nemaketani anorema. Ivo panzvimbo pezvo vakasunungurwa muropa. Aya maketani asina kusunganidzwa anozivikanwa se mahara macheni macheni.

Kune maviri marudzi emaketeni akareruka: lambda uye kappa mwenje macheni. Yemahara mwenje macheni bvunzo kuyera huwandu hwayo lambda uye kappa yemahara mwenje macheni muropa. Kana huwandu hwemaketeni emahara emahara hwakakwira kana kudzikira pane zvakajairwa, zvinogona kureva kuti une kusagadzikana kwemasero eplasma. Izvi zvinosanganisira akawanda myeloma, gomarara remasero eplasma, uye amyloidosis, mamiriro anokonzeresa ane ngozi kuvaka mapuroteni muzvikamu zvakasiyana uye nyama.

Mamwe mazita: yemahara kappa / lambda ratio, kappa / lambda chiyero chemwenje wakasununguka, freelite, kappa uye lambda yemahara macheni macheni, immunoglobulin yemahara macheni macheni.

Chii chinoshandiswa?

Yemahara mwenje maketeni bvunzo inoshandiswa kubatsira kuongorora kana kuongorora plasma maseru kusagadzikana.

Sei ini ndichida yemahara mwenje macheni bvunzo?

Iwe ungangoda bvunzo iyi kana iwe uine zviratidzo zveplasma maseru kusagadzikana. Zvichienderana nekuti uripi chirwere cheplasma chaungave nacho uye ndeapi mitezo akanganiswa, zviratidzo zvako zvinogona kusanganisira

• Kurwadziwa kwepfupa
• Kuneta
• Unhu kana kugwinha maoko nemakumbo
• Rurimi ruchizvimba
• Mavara epepuru paganda

Chii chinoitika panguva yemahara emwenje macheni bvunzo?

Nyanzvi yezvehutano inotora muyero weropa kubva mutsinga iri muruoko rwako, uchishandisa tsono diki. Mushure mekunge tsono yaiswa, kashoma reropa kanounganidzwa muthubhu yekuyedza kana muhombodo. Unogona kunzwa kakuruma kana tsono ichipinda kana kubuda. Izvi zvinowanzotora maminetsi asingasviki mashanu.

Ndichafanira here kuita chero chinhu kugadzirira bvunzo?

Iwe haudi chero yakakosha gadziriro yemahara emwenje macheni bvunzo.

Kune here chero njodzi kune yemahara mwenje macheni bvunzo?

Pane njodzi shoma yekuongororwa ropa. Unogona kunge uine marwadzo mashoma kana kupwanya panzvimbo yakaiswa tsono, asi zviratidzo zvizhinji zvinokurumidza kupera.

Zvinorevei mhedzisiro yacho?

Mhedzisiro yako icharatidza huwandu hwe lambda uye kappa yemahara macheni macheni. Izvo zvakare zvichapa kuenzanisa pakati pezviviri. Kana mhedzisiro yako yanga isiri yechinyakare, zvinogona kureva kuti une chirwere cheplasma cell disorder, senge:

• Akawanda myeloma
• Amyloidosis
• MGUS (monoclonal gammopathy yezvisingazivikanwe kukosha). Iyi ndiyo mamiriro mauri uine mapuroteni asina kujairika. Iyo inowanzo kukonzera pasina matambudziko kana zviratidzo, asi dzimwe nguva inokura kuva akawanda myeloma.
• Waldenstrom macroglobulinemia (WM), kenza yemasero machena eropa. Iyo mhando yeiyo isiri-Hodgkin lymphoma.

Dzidza zvakawanda nezve bvunzo dzemarabhoritari, mareferenzi masosi, uye mhinduro dzekunzwisisa

Pane chimwe chinhu here chandinofanira kuziva nezve yemahara mwenje macheni bvunzo?

Yemahara mwenje yemaketeni bvunzo inowanzo kurairwa pamwe nedzimwe bvunzo, kusanganisira iyo immunofixation yeropa bvunzo, kubatsira kusimbisa kana kutonga kunze kwekuongororwa.

Zvinyorwa

1. American Cancer Society [Internet]. Atlanta: American Cancer Society Inc .; c2019. Kuyedza Kutsvaga Akawanda Myeloma; [yakagadziridzwa 2018 Feb 28; yakataurwa 2019 Dec 21]; [angangoita mana skrini. Inowanikwa kubva: https://www.cancer.org/cancer/multiple-myeloma/detection-diagnosis-staging/testing.html
2. American Cancer Society [Internet]. Atlanta: American Cancer Society Inc .; c2019. Chii chinonzi Waldenstrom Macroglobulinemia ?; [yakagadziridzwa 2018 Jul 29; yakataurwa 2019 Dec 21]; [angangoita matatu skrini. Inowanikwa kubva: https://www.cancer.org/cancer/waldenstrom-macroglobulinemia/about/what-is-wm.html
3. American Society yeHematology [Internet]. Washington DC: American Society yeHematology; c2019. Myeloma; [yakataurwa 2019 Dec 21]; [angangoita matatu skrini. Inowanikwa kubva: https://www.hematology.org/Patients/Cancers/Myeloma.aspx
4. International Myeloma Foundation [Internet]. North Hollywood (CA): International Myeloma Foundation; Kunzwisisa Freelite uye Hevylite Miedzo; [yakataurwa 2019 Dec 21]; [angangoita matatu skrini. Inowanikwa kubva ku: https://www.myeloma.org/sites/default/files/resource/u-freelite_hevylite.pdf
5. Lab Kuedza Pamhepo [Internet]. Washington DC: American Association yeKiriniki Chemistry; c2001–2019. Serum Yemahara Mwenje Maketani; [yakagadziridzwa 2019 Oct 24; yakataurwa 2019 Dec 21]; [angangoita maviri skrini. Inowanikwa kubva: https://labtestsonline.org/tests/serum-free-light-chains
6. Mayo Clinic [Indaneti]. Mayo Foundation Yekurapa Dzidzo uye Tsvagiridzo; c1998–2019. Monoclonal gammopathy yekusafungidzirwa kukosha (MGUS): Zviratidzo uye zvikonzero; 2019 Chivabvu 21; [yakataurwa 2019 Dec 21]; [angangoita matatu skrini. Inowanikwa kubva: https://www.mayoclinic.org/diseases-conditions/mgus/symptoms-causes/syc-20352362
7. Mayo Clinic: Mayo Medical Laboratories [Internet]. Mayo Foundation Yekurapa Dzidzo uye Tsvagiridzo; c1995–2019. Bvunzo ID: FLCP: Immunoglobulin Yemahara Mwenje Maketani, Serum: Kliniki uye Dudziro; [yakataurwa 2019 Zvita 21; [angangoita mana skrini. Inowanika kubva: https://www.mayocliniclabs.com/test-catalog/Clinical+and+Interpretive/84190
8. National Cancer Institute [Internet]. Bethesda (MD): U.S. Department of Health and Human Services Plasma Cell Neoplasms (Inosanganisira Multiple Myeloma) Kurapa (PDQ®) –Patient Version; [yakagadziridzwa 2019 Nov 8; yakataurwa 2019 Dec 21]; [angangoita matatu skrini. Inowanikwa kubva: https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq
9. National Mwoyo, Mapapu, uye Ropa Institute [Internet]. Bethesda (MD): Dhipatimendi reUtano reU.S. Kuedzwa kweropa; [yakataurwa 2019 Dec 21]; [angangoita matatu skrini. Inowanikwa kubva: https://www.nhlbi.nih.gov/health-topics/blood-tests
10. Yunivhesiti yeRochester Medical Center [Internet]. Rochester (NY): Yunivhesiti yeRochester Medical Center; c2019. Health Encyclopedia: Yemahara Mwenje Maketani (Ropa); [yakataurwa 2019 Dec 21]; [angangoita maviri skrini. Inowanika kubva: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=serum_free_light_chains

Ruzivo ruri pane ino saiti harufanire kushandiswa sekutsiva kwehunyanzvi kurapwa kana kurairwa. Bata mupi wehutano kana iwe uine mibvunzo nezve hutano hwako.