Herceptin - Mushonga weGomarara repazamu

Zvemukati

• Chii ichochi
• Kushandisa sei
• 1. Gomarara repazamu
• 2. Kenza yemudumbu
• Zvinogona kuitika mhedzisiro

Herceptin imushonga unobva pane monoclonal antibodies, kubva kuRoche laboratory, iyo inoshanda yakanangana nekenza kenza uye inoshanda kwazvo kurwisa mamwe marudzi ekenza.

Mushonga uyu une mutengo ungangoita zviuru gumi reais uye unowanikwa kuSUS - Sistema Único de Saúde.

Chii ichochi

Herceptin inoratidzirwa pakurapa kwevanhu vane metastatic kenza yemazamu, yekutanga kenza yemazamu uye yakakwira gastric cancer.

Kushandisa sei

Herceptin inofanirwa kupihwa nevezvehutano:

1. Gomarara repazamu

Kana ikashandiswa vhiki nevhiki, yekutanga kurodha dhiyo ye4 mg / kg uremu hwemuviri hunofanirwa kupihwa seyakavharirwa mukati memaminetsi makumi mapfumbamwe. Inoteverwa mashechi evhiki nevhiki anofanirwa kuve 2 mg / kg yehuremu hwemuviri, iyo inogona kupihwa mukati memaminetsi makumi matatu-maminitsi.

Kana ikashandiswa vhiki nhatu dzese, iyo yekutanga kurodha dhiyo ndeye 8 mg / kg yehuremu hwemuviri, inoteverwa ne6 mg / kg yehuremu hwemuviri, vhiki dzese dzese nhatu, mune infusions inogara ingangoita maminetsi makumi mapfumbamwe. Kana iyi dosi ichibvumirirwa zvakanaka, iyo nguva yekumisikidzwa inogona kudzikiswa kusvika maminetsi makumi matatu.

Mushonga uyu unogona kupihwa pamwe chete ne paclitaxel kana docetaxel.

2. Kenza yemudumbu

Mushonga uyu unofanirwa kushandiswa kwega kwega kwevhiki nhatu uye yekutanga yekurwisa muyero ndeye 8 mg / kg yehuremu hwemuviri, ichiteverwa ne6 mg / kg yehuremu hwemuviri, iyo inofanirwa kudzokororwa vhiki dzese nhatu, mukumisikidzwa kunogara ingangoita maminetsi makumi mapfumbamwe. Kana iyi dosi ichibvumirirwa zvakanaka, iyo nguva yekumisikidzwa inogona kudzikiswa kusvika maminetsi makumi matatu.

Zvinogona kuitika mhedzisiro

Mhedzisiro inowanzoitika panguva yekurapwa naHerceptin ndeye nasopharyngitis, hutachiona, kupererwa neropa, thrombocytopenia, febrile neutropenia, yakaderedzwa chena masero eropa, yakaderera kana kuwedzera huremu, yakaderedza kudya, kushaya hope, dzungu, musoro, paresthesia, hypoesthesia, kuderera kwekuravira , kubvarura, conjunctivitis, lymphedema, kupisa kupisa, kufema, epistaxis, kukosora, kumhanyisa mhino uye kurwadziwa mumuromo uye pharynx.

Pamusoro pezvo, manyoka, kurutsa, kusvotwa, kurwadziwa mudumbu, kusagadzikana kugaya, kuzvimbirwa, stomatitis, erythema,mapundu, kurasikirwa nevhudzi, kushungurudzika kwembambo uye kurwadziwa kwemhasuru.

Ndiani asingafanire kushandisa

Ichi chishandiso hachifanirwe kushandiswa kune vanhu vari allergiki kune chero eimwe yezvinhu zvemufomula, vakadzi vane pamuviri uye vanoyamwisa.

Mushonga uyu hauna kuyedzwa pavana, vachiri kuyaruka, vakura uye vanhu vane hurema kana hepatic kukanganisika, uye inofanira kushandiswa nekuchenjerera.