Kurapa Sarudzo dzeCML neChikamu: Chisingaperi, Chinowedzera, uye Blast Phase

Zvemukati

• Chisingaperi chikamu CML
• Inokurumidza chikamu CML
• Blast chikamu CML
• Mamwe marapirwo
• Kuongorora kurapwa kwako
• Kutora

Chisingaperi myeloid leukemia (CML) inozivikanwawo seisingaperi myelogenous leukemia. Mumhando iyi yekenza, mwongo wemapfupa unoburitsa akawanda machena masero eropa.

Kana chirwere ichi chisina kurapwa nemazvo, chinowedzera zvishoma nezvishoma. Inogona kufambira mberi kubva kuchikamu chisingaperi, kuenda kuchikamu chinokurumidza, kuenda kuchikamu chekuputika.

Kana iwe uine CML, chirongwa chako chekurapa chinoenderana nechikamu pachikamu chechirwere.

Verenga pamusoro kuti udzidze zvakawanda nezvesarudzo dzekurapa pachikamu chimwe nechimwe.

Chisingaperi chikamu CML

CML inowanzo kuve inorapwa zvakanyanya kana ichinge yaonekwa kare, muchikamu chisingaperi.

Kurapa chisingaperi chikamu CML, chiremba wako anogona kukupa mhando yemishonga inozivikanwa se tyrosine kinase inhibitor (TKI).

Mhando dzinoverengeka dzeTKI dziripo yekurapa CML, inosanganisira:

• imatinib (Gleevec)
• nilotinib (Tasigna)
• dasatinib (Spryrcel)
• bosutinib (Bosulif)
• ponatinib (Iclusig)

Gleevec kazhinji ndiyo yekutanga mhando yeTKI yakatemerwa CML. Nekudaro, Tasigna kana Spryrcel inogona zvakare kunyorerwa sekutanga-kurapwa kurapwa.

Kana idzo mhando dzeTKI dzikasashanda zvakanaka kwauri, rega kushanda, kana kukonzera kusagadzikana kusingaite mhedzisiro, chiremba wako anogona kunyorera Bosulif.

Chiremba wako anongoraira chete Iclusig kana gomarara rikasapindura zvakanaka kune mamwe marudzi emaTKI kana ikaita mhando yekuchinja kwemajini, inozivikanwa sekuchinja kweT315I.

Kana muviri wako ukasapindura zvakanaka kumaTKI, chiremba wako anogona kupa mishonga yemakemikari kana mhando yemishonga inozivikanwa se interferon kurapa chisingaperi chikamu CML.

Mune zvisingawanzoitika zviitiko, ivo vanogona kukurudzira iyo stem cell kuisirwa. Nekudaro, kurapwa uku kunowanzo shandiswa kurapa kukurumidza chikamu CML.

Inokurumidza chikamu CML

Muchikamu chinokurumidza CML, masero eleukemia anotanga kuwanda nekukurumidza. Iwo maseru anowanzo gadzira shanduko yegene inowedzera kukura kwavo uye inoderedza kushanda kwekurapa.

Kana iwe ukawedzera chikamu cheCML, chirongwa chako chekurapa chakakurudzirwa chinoenderana nemarapirwo awakagamuchira kare.

Kana usati wambowana chero kurapwa kweCML, chiremba wako anogona kunyorera TKI kuti itange.

Kana iwe watove uchitora TKI, chiremba wako anogona kuwedzera dosi yako kana kukuchinjira kune imwe mhando yeTKI. Kana masero ekenza yako aine T315I mutation, anogona kupa Iclusig.

Kana maTKI asingashande zvakanaka kwauri, chiremba wako anogona kuraira kurapwa ne interferon.

Mune zvimwe zviitiko, chiremba wako anogona kuwedzera chemotherapy kuchirongwa chako chekurapa. Chemotherapy mishonga inogona kubatsira kuunza kenza mukuregererwa, asi inowanzo mira kushanda nekufamba kwenguva.

Kana iwe uri mudiki uye uine hutano hwakanaka, chiremba wako anogona kukurudzira stem cell kuisirwa mushure mekupfuura nekumwe kurapwa. Izvi zvinobatsira kuzadza masero ako anogadzira ropa.

Mune autologous stem cell yekuisa, chiremba wako anozotora mamwe ako maseru masero usati wawana kurapwa. Mushure mekurapwa, vanozopa aya maseru kudzokera mumuviri wako.

Mune allogenic stem cell yekuisa, chiremba wako anokupa iwe maseru maseru kubva kune anonyatsoenderana mupi. Ivo vanogona kutevedzera iko kuisirwa pamwe nekuiswa kweye chena masero eropa kubva kune anenge apa.

Chiremba wako angangoedza kuunza kenza mukuregererwa nemishonga vasati vapa zano rekusimudza masero.

Blast chikamu CML

Muchikamu chekuputika CML, maseru emukenza anokurumidza kuwanda uye anokonzeresa zvimwe zvinoonekwa zviratidzo.

Mishonga inowanzove isinganyanyo kushanda panguva yechikamu chekuputika, ichienzaniswa nezvikamu zvekutanga zvechirwere. Nekuda kweizvozvo, vanhu vazhinji vane blast phase CML havagone kurapwa chirwere checancer.

Kana iwe ukagadzira blast phase CML, chiremba wako anozofunga nezve yako yekutanga nhoroondo yekurapa.

Kana iwe usati wagamuchira chero kurapwa kwekare kweCML, ivo vanogona kupa yakakwira madosi eTKI.

Kana iwe watove uchitora TKI, vanogona kuwedzera dosi yako kana kukupa zano kuti uchinjire kune imwe mhando yeTKI. Kana masero eleukemia aine T315I mutation, anogona kupa Iclusig.

Chiremba wako anogona zvakare kuraira chemotherapy kuti ubatsire kudzikisa kenza kana kubvisa zviratidzo. Zvisinei, chemotherapy inowanzove isinganyanyi kushanda muchikamu chekuputika kupfuura muzvikamu zvekare.

Kana chimiro chako chikapindura mushe pakurapwa nemushonga, chiremba wako anogona kukurudzira stem cell yekuisa. Zvisinei, kurapwa uku kunowanzoita kunge kusinganyatsobudirira muchikamu chekuputika.

Mamwe marapirwo

Pamusoro pekurapa kwakatsanangurwa pamusoro, chiremba wako anogona kupa mishonga yekurapa kuti ibatsire kubvisa zviratidzo kana kurapa zvingangoita zvinonetsa zveCML.

Semuenzaniso, ivo vanogona kuraira:

• maitiro anozivikanwa se leukapheresis kubvisa machena masero eropa kubva muropa rako
• kukura zvinhu zvekusimudzira mwongo wekupora, kana iwe ukapfuura nekemotherapy
• kuvhiya kubvisa yako spleen, kana ikawedzera
• radiation radiation, kana iwe ukawedzera yakawedzera spleen kana kurwadziwa kwepfupa
• mishonga inorwisa mabhakitiriya, antiviral, kana antifungal mishonga, kana iwe ukava nechero hutachiona
• kuwedzerwa ropa kana plasma

Ivo vanogona zvakare kukurudzira kurairwa kana kumwe kutsigirwa kwehutano hwepfungwa, kana iwe uchiona zvichinetsa kurarama nemagariro kana nemanzwiro emamiriro ako.

Mune zvimwe zviitiko, ivo vanogona kukukurudzira iwe kunyoresa mukuedzwa kwekiriniki kuti uwane kurapwa kwekuyedza kweCML. Mishonga mitsva irikugadzirwa uye kuongororwa chirwere ichi.

Kuongorora kurapwa kwako

Paunenge uchirapwa CML, chiremba wako anogona kuraira kuongororwa ropa nguva dzose kuti atarise kuti muviri wako uri kupindura sei.

Kana chirongwa chako chazvino chekurapa chichiita senge chiri kushanda nemazvo, chiremba wako anogona kukuraira kuti uenderere mberi nechirongwa ichocho.

Kana kurapa kwako kwazvino kuchiratidzika kunge kuri kushanda mushe kana kushomeka nekufamba kwenguva, chiremba wako anogona kukunyorera mishonga yakasiyana kana mamwe marapirwo.

Vanhu vazhinji vane CML vanofanirwa kutora TKI kwemakore akati wandei kana nekusingaperi.

Kutora

Kana iwe uine CML, chirongwa chinokurudzirwa nachiremba wako chinoenderana nechikamu chechirwere, pamwe nezera rako, hutano hwese, uye nhoroondo yekurapa kwakapfuura.

Mishonga yakati wandei inowanikwa kubatsira kunonoka kukura kwekenza, kudzikira mamota, uye kubvisa zviratidzo. Kurapa kunowanzoita kushoma sezvo chirwere ichi chichienderera mberi.

Taura nachiremba wako kuti udzidze zvakawanda nezvesarudzo dzako dzekurapa, kusanganisira izvo zvinogona kubatsira uye njodzi dzenzira dzakasiyana dzekurapa.