Voriconazole

Zvemukati

• Zviratidzo zveVoriconazole
• Voriconazole mutengo
• Side Migumisiro yeVoriconazole
• Contraindications yeVoriconazole
• Mashandisiro ekushandisa Voriconazole

Voriconazole ndicho chinhu chinoshanda mumushonga unodzivirira unozivikanwa nekutengesa seVfend.

Mushonga uyu wekushandisa pamuromo unobaya jekiseni uye unoratidzwa pakurapa aspergillosis, sezvo chiito chayo chinokanganisa ergosterol, chinhu chakakosha kuchengetedza kutendeka kwefungal cell membrane, iyo inoguma yapera simba uye kubviswa mumuviri.

Zviratidzo zveVoriconazole

Aspergillosis; yakanyanya fungal hutachiona.

Voriconazole mutengo

Iyo 200 mg bunch yeVoriconazole ine ampoule inodhura ingangoita 1,200 reais, iyo 200 mg yekushandisa yemuromo bhokisi ine mapiritsi e14 anodhura angangoita 5,000 reais.

Side Migumisiro yeVoriconazole

Kuwedzera creatinine; kutaridzika kwekuona (kuchinjika kana kuwedzera pakuona kwekuona; kuona kwakashata; kuchinjika kwemavara ekuona, kunzwisisika kune mwenje).

Contraindications yeVoriconazole

Dambudziko rePamuviri D; vakadzi vanoyamwisa; hypersensitivity kune chigadzirwa kana zvimwe maozo; galactose kusagadzikana; lactase kushomeka.

Mashandisiro ekushandisa Voriconazole

Jekiseni Kushandisa

Kupinza infusion.

Vakuru

• Kurwisa dose: 6 mg pa kg yehuremu hwemuviri maawa gumi nemaviri e2 doses, ichiteverwa nedosi yekuchengetedza ye4 mg pa kg yehuremu hwemuviri maawa gumi nemaviri. Nokukurumidza sezvazvinogona (sekureba sekunge murwere achitsungirira), chinja kumuromo. Kana murwere asingashiviriri, dzikisa kusvika 3 mg pa kg yehuremu hwemuviri pa12 h.
• Vakuru: muyero wakafanana nevakuru.
• Varwere vane hunyoro kusvika pakati nepakati kutadza kwechiropa: cheka muyero wekuchengetedza muhafu.
• Varwere vane chiropa chakakomba cirrhosis: shandisa chete kana mabhenefiti akakunda njodzi.
• Vana vanosvika makore gumi nemaviri: kuchengetedzeka uye kushanda zvisina kusimbiswa.

Kushandisa nemuromo

Vakuru

• Kuyera anopfuura makumi mana makirogiramu: Iyo yekuchengetedza dosi ndeye 200 mg maawa ese gumi nemaviri, kana mhinduro yacho isina kukwana, iyo dosi inogona kuwedzerwa kusvika ku 300 mg maawa ese gumi nemaviri (kana murwere asingashiviriri, ita zvinowedzera zve50 mg maawa ese gumi nemaviri).
• Iine isingasviki 40 kg yehuremu: Iyo yekuchengetedza dosi ye100 mg maawa ese gumi nemaviri, kana mhinduro isina kukwana, iyo dosi inogona kuwedzerwa kusvika ku150 mg kwemaawa ese gumi nemaviri (kana murwere asingashiviriri, ideredze kusvika ku100 mg maawa gumi nemaviri ese).
• Varwere vane chiropa kutadza: kuderedzwa kwedosi kunogona kudikanwa.
• Vakuru: madosi akafanana nevakuru.
• Vana vanosvika makore gumi nemaviri: kuchengetedzeka uye kushanda zvisina kusimbiswa.