Cholestasis

Cholestasis chero mamiriro ezvinhu umo kuyerera kwe bile kubva muchiropa kunononoka kana kudzivirirwa.

Kune zvikonzero zvakawanda zve cholestasis.

Extrahepatic cholestasis inoitika kunze kwechiropa. Inogona kukonzerwa ne:

• Bile duct tumarara
• Cysts
• Kuderedza kweiyo bile duct (strictures)
• Matombo mune yakajairwa bile duct
• Pancreatitis
• Pancreatic bundu kana pseudocyst
• Kushushikana pane iyo bile ducts nekuda kwenzvimbo iri padyo kana bundu
• Chikuru sclerosing cholangitis

Intrahepatic cholestasis inoitika mukati mechiropa. Inogona kukonzerwa ne:

• Chinodhakwa chiropa chirwere
• Amyloidosis
• Hutachiona hutachiona muchiropa
• Kupihwa kudya chete kuburikidza netsinga (IV)
• Lymphoma
• Kubata pamuviri
• Primary biliary cirrhosis
• Yekutanga kana metastatic kenza yechiropa
• Chikuru sclerosing cholangitis
• Sarcoidosis
• Zvirwere zvakakomba zvakapararira kuburikidza neropa (sepsis)
• Tiibhii
• Utachiona hepatitis

Mimwe mishonga inogona zvakare kukonzera cholestasis, inosanganisira:

• Mishonga inorwisa mabhakitiriya, yakadai seampicillin nemamwe mapenicillin
• Anabolic steroids
• Mapiritsi ekudzivirira kubata pamuviri
• Chlorpromazine
• Cimetidine
• Estradiol
• Imipramine
• Prochlorperazine
• Terbinafine
• Tolbutamide

Zviratidzo zvinogona kusanganisira:

• Clay-mavara kana machena zvituru
• Weti yakasviba
• Kutadza kugaya zvimwe zvekudya
• Itching
• Kusvotwa kana kurutsa
• Marwadzo muchikamu chepamusoro chepamusoro chedumbu
• Ganda reyero kana maziso

Kuongororwa kweropa kunogona kuratidza kuti wakwidziridza bilirubin uye alkaline phosphatase.

Kufungidzira bvunzo kunoshandiswa kuongorora mamiriro aya. Miedzo inosanganisira:

• CT scan yemudumbu
• MRI yemudumbu
• Endoscopic retrograde cholangiopancreatography (ERCP), inogona zvakare kuona chikonzero
• Ultrasound yemudumbu

Chikonzero chinokonzera cholestasis chinofanirwa kurapwa.

Kuita zvakanaka kwemunhu kunoenderana nechirwere chinokonzera mamiriro acho. Matombo mune yakajairwa bile duct anowanzo bviswa. Izvi zvinogona kuporesa cholestasis.

Masisitimu anokwanisa kuiswa munzvimbo dzinovhurika dzeiyo yakajairika bile duct iyo yakatetepa kana kuvharirwa nekenza.

Kana mamiriro akakonzerwa nekushandiswa kwemumwe mushonga, unowanzoenda kana iwe ukarega kutora iwo mushonga.

Zvinetso zvinogona kusanganisira:

• Manyoka
• Kukundikana kwemuviri kunogona kuitika kana sepsis ichikura
• Kusatora zvakanaka mafuta nemafuta-akasviba mavhithamini
• Kukuvadza kukuru
• Mapfupa asina kusimba (osteomalacia) nekuda kwekuve necholestasis kwenguva yakareba kwazvo

Fonera wako mupi wezvehutano kana iwe uine:

• Kuchema uko hakuendi
• Ganda reyero kana maziso
• Zvimwe zviratidzo zve cholestasis

Wana jekiseni rehepatitis A uye B kana iwe uri panjodzi. Usashandise mishonga inopinza uye ugovane tsono.

Intrahepatic cholestasis; Yakawedzera cholestasis cholestasis

• Matombo
• Gallbladder
• Gallbladder

Eaton JE, Lindor KD. Chekutanga biliary cholangitis. Muna: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger uye Fordtran's Gastrointestinal uye Chirwere Chiropa. 11th ed. Philadelphia, PA: Elsevier; 2021: chits. 91.

Fogel EL, Sherman S. Zvirwere zveguruva uye bile ducts. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chap 146.

Lidofsky SD. Jaundice. Muna: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger uye Fordtran's Gastrointestinal uye Chirwere Chiropa. 11th ed. Philadelphia, PA: Elsevier; 2021: chitsiko 21.