VIPoma

VIPoma kenza isingawanzo kuwanikwa inowanzo kukura kubva mumasero ari mupancreas anonzi islet masero.

VIPoma inokonzeresa maseru mupancreas kuti abudise huwandu hwehomoni inonzi vasoactive intestinal peptide (VIP). Iyi hormone inowedzera zvakavanzika kubva mumatumbu. Iyo zvakare inodzoreredza mimwe yemhasuru dzakatsetseka mugadziriro yemudumbu.

Chikonzero chaicho cheVIPomas hachizivikanwe.

VIPomas anowanzoonekwa muvakuru, kazhinji ane makore angangoita makumi mashanu. Vakadzi vane mukana wekubatwa zvakanyanya kupinda varume. Gomarara iri rinoshoma. Gore rega rega, vangangoita 1 muvanhu gumi miriyoni vanoonekwa vaine VIPoma.

Zviratidzo zveVIPoma zvinogona kusanganisira chero yeanotevera:

• Kutambudzika kwepamuviri uye kupwanya
• Dhairrhea (mvura, uye kazhinji yakawanda)
• Kupera mvura mumuviri
• Kumhanya kana kutsvuka kwechiso
• Tsandanyama cramps nekuda kwekudzikira kweropa potasium (hypokalemia)
• Nausea
• Kuonda

Anopa hutano anoita bvunzo dzepanyama uye obvunza nezve nhoroondo yako yezvokurapa nezviratidzo.

Miedzo inogona kuitwa inosanganisira:

• Ropa chemistry bvunzo (yakakosha kana yakazara metabolic pani)
• CT scan yemudumbu
• MRI yemudumbu
• Stool kuongororwa kwechikonzero chemanyoka uye e electrolyte mazinga
• Chikamu cheVIP muropa

Chinangwa chekutanga chekurapa ndechekugadzirisa kupera mvura mumuviri. Mvura inowanzopihwa kuburikidza nemutsinga (intravenous fluids) kutsiva zvinwiwa zvinorasika kuburikidza nemanyoka.

Chinangwa chinotevera kudzora manyoka. Mishonga inogona kubatsira kudzora manyoka. Mumwe wemishonga yakadaro ndeye octreotide. Icho chimiro chakagadzirwa chehomoni yechisikirwo iyo inovhara chiitiko cheVIP.

Mukana wakanakisisa wemushonga kuvhiya kubvisa bundu. Kana bundu risina kupararira kune dzimwe nhengo, kuvhiyiwa kunogona kupodza mamiriro acho.

Unogona kudzikisira kushushikana kwehurwere nekujoinha boka rekutsigira gomarara. Kugovana nevamwe vane zvakajairika zviitiko uye matambudziko zvinogona kukubatsira kuti usazonzwa kusurukirwa.

Kuvhiya kunowanzo kurapa VIPomas. Asi, muchikamu chimwe muzvitatu kusvika kuhafu chevanhu, bundu rakapararira nenguva yekuongororwa uye harigoni kurapwa.

Zvinetso zvinogona kusanganisira:

• Kenza inopararira (metastasis)
• Cardiac kusungwa kubva pasi yeropa potasiyamu
• Kupera mvura mumuviri

Kana uine manyoka emvura kweanopfuura mazuva maviri kusvika matatu, danaidza mupi wako.

Vasoactive mudumbu peptide-inogadzira bundu; VIPoma chirwere; Pancreatic endocrine bundu

• Pancreas

National Cancer Institute webhusaiti. Pancreatic neuroendocrine tumors (islet cell tumors) kurapwa (PDQ) - hutano nyanzvi vhezheni. www.cancer.gov/types/pancreatic/hp/pnet-treatment-pdq. Yakagadziridzwa Kukadzi 8, 2018. Yakasvika munaNovember 12, 2018.

Schneider DF, Mazeh H, Lubner SJ, Jaume JC, Chen H. Kanzera yeiyo endocrine system. Mune: Niederhuber JE, Armitage JO, Doroshow JH, Kastan MB, Tepper JE, eds. Abeloff's Clinical Oncology. 5 ed. Philadelphia, PA: Elsevier Saunders; 2014: chits.

Vella A. Mahormoni emudumbu uye matumbu endocrine tumarara. Mune: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Chinyorwa cheEndocrinology. 13 ed. Philadelphia, PA: Elsevier; 2016: chitsiko 38.