Pheochromocytoma

Pheochromocytoma ibundu risingawanzo readrenal gland tishu. Izvo zvinoguma nekuburitswa yakawandisa epinephrine uye norepinephrine, mahormone anodzora kurova kwemoyo, metabolism, uye BP.

Pheochromocytoma inogona kuitika seimwe bundu kana seanopfuura kukura kumwe. Inowanzo kukura mukati (medulla) yeimwe kana maviri adrenal gland. Idzo adrenal gland idiki mbiri dzakaumbwa-katatu. Imwe gland iri pamusoro petsvo imwe neimwe. Mune zvisingawanzo zviitiko, pheochromocytoma inoitika kunze kwedrenal gland. Kana zvikaitika, zvinowanzove kumwe kunhu mudumbu.

Akashoma pheochromocytomas ane cancer.

Mamota anogona kuitika chero pazera, asi iwo anowanzoitika kubva pakutanga kusvika pakati pekukura.

Mune mashoma zviitiko, mamiriro acho anogona zvakare kuonekwa pakati penhengo dzemhuri (nhaka).

Vazhinji vanhu vane bundu iri vanorwiswa nezviratidzo, izvo zvinoitika kana bundu rikaburitsa mahormone. Kurwiswa kunowanzotora kubva pamaminetsi mashoma kusvika maawa. Iyo seti yezviratidzo inosanganisira:

• Kutemwa nemusoro
• Mwoyo palpitations
• Kudikitira
• Kuwedzera kweropa

Sezvo bundu rinokura, kurwiswa kunowanzo wedzera mukuwanda, kureba, uye kuomarara.

Zvimwe zviratidzo zvinogona kuitika zvinosanganisira:

• Dumbu kana kurwadziwa pachipfuva
• Kushatirwa, kutya
• Pallor
• Kuonda
• Kusvotwa uye kurutsa
• Kufema kwekufema
• Kufenda
• Matambudziko ekurara

Anopa hutano anoita bvunzo dzepanyama. Iwe uchazobvunzwa nezve yako nhoroondo yezvokurapa uye zviratidzo.

Bvunzo dzinoitwa dzinogona kusanganisira:

• Abdominal CT scan
• Adrenal biopsy
• Catecholamines ropa bvunzo (serum catecholamines)
• Glucose bvunzo
• Metanephrine ropa bvunzo (serum metanephrine)
• Chiyero chekufungidzira chinonzi MIBG scintiscan
• MRI yemudumbu
• Weti catecholamines
• Weti metanephrines
• PET scan yedumbu

Kurapa kunosanganisira kubvisa bundu nekuvhiya. Izvo zvakakosha kudzikamisa yako BP uye kupomba nemimwe mishonga usati wavhiyiwa. Iwe ungangoda kugara muchipatara uye uine zviratidzo zvako zvakakosha zvichinyatso tariswa panguva yekuvhiyiwa. Mushure mekuvhiyiwa, zviratidzo zvako zvakakosha zvicharamba zvichiongororwa munzvimbo yevanotarisirwa.

Kana bundu rikasagona kuvhiyiwa, uchafanira kutora mushonga kuti uzvigadzirise. Musanganiswa wemishonga unowanzo fanirwa kudzora mhedzisiro yemamwe mahormone. Radiation kurapa uye chemotherapy hazvina kunge zvichishanda pakurapa rudzi urwu rwebundu.

Vazhinji vanhu vane isina mamota mamota ayo anobviswa nekuvhiyiwa vachiri vapenyu mushure memakore mashanu. Mamota anodzoka mune vamwe vanhu. Nhanho dzemahormone norepinephrine uye epinephrine dzinodzokera pane zvakajairwa mushure mekuvhiyiwa.

Kuenderera mberi kweropa repamusoro kunogona kuitika mushure mekuvhiyiwa. Kurapa kwakajairika kazhinji kunogona kudzora kukwira kweropa.

Vanhu vakabudirira kurapwa pheochromocytoma vanofanirwa kuongororwa nguva nenguva kuti vaone kuti bundu harina kudzoka. Nhengo dzemhuri dzepedyo dzinogona zvakare kubatsirwa nekuyedzwa, nekuti mamwe makesi anogarwa nhaka.

Fonera mupiki wako kana iwe:

• Iva nezviratidzo zve pheochromocytoma, senge kutemwa nemusoro, kudikitira, uye kurovera moyo
• Wakanga uine pheochromocytoma munguva yakapfuura uye zviratidzo zvako zvinodzoka

Chromaffin bundu; Paraganglionoma

• Endocrine masero
• Adrenal metastases - CT scan
• Adrenal Tumor - CT
• Adrenal gland hormone kuchengetedzwa

National Cancer Institute webhusaiti. Pheochromocytoma uye paraganglioma kurapwa (PDQ) - hutano nyanzvi vhezheni. Cancer.gov. www.cancer.gov/types/pheochromocytoma/hp/pheochromocytoma-treatment-pdq#link/_38_toc. Yakagadziridzwa Nyamavhuvhu 23, 2020. Yakasvika Gumiguru 14, 2020.

Pacak K, Nguva dzeHJLM, Eisenhofer G. Pheochromocytoma. Muna: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Vakuru uye Chiremba. 7th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 110.

Brigode WM, Miraflor EJ, Palmer BJA. Iyo manejimendi ye pheochromocytoma. Mune: Cameron AM, Cameron JL, eds. Parizvino Kuvhiya Therapy. 13 ed. Philadelphia, PA: Elsevier; 2020: 750-756.