Von Willebrand chirwere

Von Willebrand chirwere ndicho chinowanzoitika nhaka yekubuda ropa kusagadzikana.

Von Willebrand chirwere chinokonzerwa nekushomeka kwe von Willebrand factor. Von Willebrand chinhu chinobatsira maplatelet eropa kuumbana pamwe nekunamatira kumadziro eropa remidziyo, izvo zvinodikanwa pakuvhara kweropa zvakajairika. Kune akati wandei marudzi e von Willebrand chirwere.

Nhoroondo yemhuri yechirwere chekubuda ropa ndiyo inonyanya kukonzera njodzi.

Zviratidzo zvinogona kusanganisira:

• Kuenda kumwedzi zvisina kujairika
• Kubuda ropa kwematadza
• Kutuka
• Mhino dzemhino
• Mapundu eganda

Ongorora: Vazhinji vakadzi vane rinorema kana rakareba kubuda kwekuenda kumwedzi havana von von Willebrand chirwere.

Von Willebrand chirwere chingave chakaoma kuongorora. Low von Willebrand factor mazinga uye kubuda ropa hazvireve kuti une chirwere che von Willebrand.

Kuyedza kunogona kuitwa kuongorora chirwere ichi kunosanganisira:

• Nguva yekubuda ropa
• Kunyorera ropa
• Factor VIII nhanho
• Platelet basa kuongorora
• Platelet kuverenga
• Ristocetin cofactor bvunzo
• Von Willebrand factor chaiyo bvunzo

Kurapa kunogona kusanganisira DDAVP (desamino-8-arginine vasopressin). Ndiwo mushonga wekusimudza von Willebrand factor level uye kudzikisa mikana yekubuda ropa.

Nekudaro, DDAVP haishande kumhando dzese dzechirwere cheVon Willebrand. Miedzo inofanirwa kuitwa kuti uone kuti ndeupi rudzi rwe von Willebrand wauinayo. Kana iwe uchizovhiyiwa, chiremba wako anogona kukupa DDAVP usati wavhiyiwa kuti uone kana yako von Willebrand factor mazinga achiwedzera.

Mushonga weAlphanate (antihemophilic factor) unobvumidzwa kudzikisa kubuda kweropa kune vanhu vane chirwere vanofanirwa kuvhiyiwa kana chero imwe nzira inoparadza.

Ropa plasma kana chimwe chinhu VIII gadziriro inogona zvakare kushandiswa kudzikisa kubuda kweropa.

Kubuda ropa kunogona kuderera panguva yekuzvitakura. Vakadzi vane chirwere ichi kazhinji havana kubuda ropa kwakanyanya panguva yekusununguka.

Ichi chirwere chinopfuudzwa kuburikidza nemhuri. Kurairidzwa kwemageneti kunogona kubatsira vanotarisira vabereki kunzwisisa njodzi yevana vavo.

Kubuda ropa kunogona kuitika mushure mekuvhiyiwa kana kana iwe uchinge wadhonzwa zino.

Aspirin uye mamwe asiri -steroidal anti-anogumbura (NSAIDs) anogona kuita kuti mamiriro aya awedzere. Usatore mishonga iyi usati watanga kutaura nemupi wako wezvehutano.

Fonera mupiki wako kana kubuda ropa kukaitika pasina chikonzero.

Kana iwe uine von Willebrand chirwere uye wakarongerwa kuvhiyiwa kana uri mutsaona, ita shuwa kuti iwe kana mhuri yako muudze vanopa nezve mamiriro ako.

Kubuda ropa kusagadzikana - von Willebrand

• Ropa kugadzirwa
• Ropa rinovhara

Mafashama VH, Scott JP. Von Willebrand chirwere. Mune: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chap 504.

James P, Rydz N. Chimiro, bhayoroji, uye genetics ya von Willebrand factor. Muna: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Misimboti uye Maitiro. 7th ed. Philadelphia, PA: Elsevier; 2018: chitsiko 138.

Neff AT. Von Willebrand chirwere uye hemorrhagic kukanganisika kweplatelet uye vascular basa. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chap 164.

Samuels P. Hematologic matambudziko epamuviri. Mune: Landon MB, Galan HL, Jauniaux ERM et al, eds. Obstetrics yaGabbe: Yakajairika uye Dambudziko Pamuviri. 8th ed. Philadelphia, PA: Elsevier; 2021: chits. 49.