Factor V kushomeka

Chinhu cheV kushomeka chirwere chekubuda ropa chinopfuudzwa kuburikidza nemhuri. Inokanganisa kugona kweropa kuvhara.

Kuvhara ropa inzira yakaoma kunzwisisa inosanganisira mapuroteni akasiyana makumi maviri muplasma yeropa. Aya mapuroteni anonzi eropa coagulation zvinhu.

Chinhu chinoshomeka cheFactor V chinokonzerwa nekushaikwa kwechikonzero V. Kana zvimwe zvinogwambisa ropa zvakaderera kana kushaikwa, ropa rako harivharike zvakanaka.

Chinhu cheV kushomeka hachiwanzoitika. Inogona kukonzerwa ne:

• Chinhu chakaremara V gene rakapfuura nemumhuri (rakagara nhaka)
• Antibody inopesana neyakajairika chinhu V mashandiro

Unogona kugadzira antibody inokanganisa chinhu V:

• Mushure mekusununguka
• Mushure mekurapwa neimwe mhando ye fibrin glue
• Mushure mekuvhiyiwa
• Nezvirwere zve autoimmune uye mamwe cancer

Dzimwe nguva chikonzero chacho hachizivikanwe.

Chirwere ichi chakafanana nehemophilia, kunze kwekubuda ropa muzvibatanidzwa kushoma. Mune chimiro chakagarwa nhaka chechinhu V kushomeka, nhoroondo yemhuri yechirwere chekubuda ropa iri njodzi.

Kuwedzeredza kubuda ropa nekuenda kumwedzi uye mushure mekubereka kazhinji kunoitika. Zvimwe zviratidzo zvinogona kusanganisira:

• Kubuda ropa mukati meganda
• Kubuda ropa kwematadza
• Kunyanya kupwanya
• Mhino dzemhino
• Kurasikirwa kwenguva refu kana kwakanyanyisa kweropa nekuvhiyiwa kana kushungurudzika
• Chigadziko wembilical ichibuda ropa

Kuyedza kuona kushomeka kwechikonzero V kunosanganisira:

• Factor V kuyedza
• Ropa rekuvhara ropa bvunzo, kusanganisira chikamu chetromboplastin nguva (PTT) uye nguva yeprothrombin
• Nguva yekubuda ropa

Iwe unozopihwa nyowani yeropa plasma kana nyowani akaomeswa echando plasma infusions panguva yekubuda ropa chikamu kana mushure mekuvhiyiwa. Aya marapirwo achagadzirisa kushomeka kwechinguva.

Maonero acho akanaka nekuongororwa uye kurapwa kwakakodzera.

Kubuda ropa kwakanyanya (kubuda ropa) kunogona kuitika.

Enda kuimba yekukurumidzira kana kufonera 911 kana iyo yemuno emergency nhamba kana uine zvisingatsanangurike kana kwenguva refu kurasikirwa kweropa.

Parahemophilia; Owren chirwere; Kubuda ropa kusagadzikana - chinhu V kushomeka

• Ropa kugadzirwa
• Ropa rinovhara

Gailani D, Wheeler AP, Neff AT. Kazhinji coagulation factor kushaikwa. Muna: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Basic Misimboti uye Maitiro. 7th ed. Philadelphia, PA: Elsevier; 2018: chits. 137.

Ragni MV. Hemorrhagic kusagadzikana: coagulation factor kushomeka. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 26th ed. Philadelphia, PA: Elsevier; 2020: chits. 165.

Scott JP, Mafashama VH. Hereditary clotting factor kushomeka (kubuda ropa kusagadzikana). Mune: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. Nelson Chinyorwa chePediatrics. 21st ed. Philadelphia, PA: Elsevier; 2020: chitsiko 503.