Pituitary bundu

Bundu repituitary kukura zvisina kujairika mupituitary gland. Iyo pituitary idiki gland iri pasi peuropi. Inogadzirisa mwero wemuviri wemahormone mazhinji.

Mazhinji mamota pituitary haana-cancer (benign). Kusvika ku20% yevanhu vane pituitary tumors. Mazhinji emamota aya haakonzeri zviratidzo uye haatomboonekwa panguva yekurarama kwemunhu.

Iyo pituitary chikamu cheiyo endocrine system. Iyo pituitary inobatsira kudzora kuburitswa kwemahormone kubva kune mamwe endocrine gland, senge iyo thyroid, gland gland (testes kana ovaries), uye adrenal gland. Iyo pituitary inoburitsa mahormone ayo anokanganisa zvakananga nyama dzemuviri, senge mapfupa uye mazamu emukaka wemuzamu. Mahormone epituitary anosanganisira:

• Adrenocorticotropic hormone (ACTH)
• Kukura kwehomoni (GH)
• Prolactin
• Utachiona-hunokurudzira mahormone (TSH)
• Luteinizing hormone (LH) uye follicle-inosimudzira mahormone (FSH)

Sezvo bundu repituitary rinokura, akajairika mahormone-anoburitsa maseru epituitary anogona kukuvara. Izvi zvinoguma kuti chirwere chepituitary chisabudise zvakakwana mahomoni ayo. Aya mamiriro anonzi hypopituitarism.

Zvinokonzera mapituitary tumors hazvizivikanwe. Mamwe mamota anokonzerwa nehutano hwekugara nhaka senge akawanda endocrine neoplasia I (MEN I).

Iyo pituitary gland inogona kukanganisirwa nemamwe matumbo ehuropi ayo anokura mune imwechete chikamu cheuropi (dehenya base), zvichikonzera zviratidzo zvakafanana.

Mamwe mamota pituitary anogadzira akawandisa eimwe kana akawanda mahormone. Nekuda kweizvozvo, zviratidzo zveimwe kana kupfuura zveanotevera mamiriro anogona kuitika:

• Hyperthyroidism (thyroid shwanu inogadzira mahormone ayo akawandisa, ichi chiitiko chisingawanzoitika chematumbo epituitary)
• Cushing syndrome (muviri une yakakwira kupfuura yakajairwa chikamu chehormone cortisol)
• Gigantism (kukura kusingaenzaniswi nekuda kwekukwirisa kupfuura zvakajairika danho rekukura kwehomoni panguva yehucheche) kana acromegaly (yakakwira kupfuura yakajairwa nhanho yekukura kwehormone muvakuru)
• Kubuda kwemboro uye zvisina kujairika kana kusaenda kumwedzi kumadzimai
• Yakadzikira kuita zvepabonde muvarume

Zviratidzo zvinokonzerwa nekumanikidza kubva kune hombe pituitary bhuru zvinogona kusanganisira:

• Shanduko mune zvakaratidzwa senge kuona kaviri, kutaridzika kwekurasikirwa kwemunda (kurasikirwa kwemaonero ekuona), kudonhedza maziso kana shanduko mumaonero ekuona.
• Kutemwa nemusoro.
• Kushaya simba.
• Nasal drainage yeakajeka, ane munyu mvura.
• Kusvotwa uye kurutsa.
• Matambudziko nemanzwiro ekunhuwidza.
• Muzviitiko zvisingawanzoitika, izvi zviratidzo zvinongoerekana zvaitika uye zvinogona kuve zvakanyanya (pituitary apoplexy).

Mutapi wako wezvehutano anozoongorora muviri. Iye mupi anoona chero matambudziko ane maviri maonero uye anoonekwa munda, sekushayikwa kwedivi (peripheral) kuona kana kugona kuona mune dzimwe nzvimbo.

Iyo bvunzo ichaongorora zviratidzo zveyakawanda cortisol (Cushing syndrome), yakawandisa kukura kwehomoni (acromegaly), kana yakawandisa prolactin (prolactinoma).

Kuyedza kutarisa endocrine basa kunogona kurairwa, kusanganisira:

• Cortisol mazinga - dexamethasone kudzvinyirira bvunzo, weti cortisol bvunzo, salivary cortisol bvunzo
• FSH mwero
• Insulin kukura chinhu-1 (IGF-1) nhanho
• LHlevel
• Chikamu cheprolactin
• Testosterone / estradiol mazinga
• Utachiona hwehutachiona mazinga - yemahara T4 bvunzo, TSH bvunzo

Kuyedza kunobatsira kusimbisa kuongororwa kunosanganisira zvinotevera:

• Minda yekuona
• MRI yemusoro

Kuvhiya kubvisa bundu kunowanzo kudikanwa, kunyanya kana bundu racho richimanikidza tsinga dzinodzora kuona (tsinga dzemaziso).

Kazhinji yenguva, pituitary tumors inogona kuvhiyiwa kubviswa kuburikidza nemhino uye zvitadzo. Kana bundu risingakwanise kubviswa nenzira iyi, rinobviswa kuburikidza nedehenya.

Radiation therapy inogona kushandiswa kudzikisira bundu muvanhu vasingakwanise kuvhiyiwa. Inogona zvakare kushandiswa kana bundu radzoka mushure mekuvhiyiwa.

Mune zvimwe zviitiko, mishonga inorayirwa kudzikisira mamwe marudzi emota.

Izvi zviwanikwa zvinogona kupa rumwe ruzivo nezve pituitary tumors:

• National Cancer Institute - www.cancer.gov/types/pituitary
• Pituitary Network Association - pituitary.org
• Iyo Pituitary Sosaiti - www.pituitarysociety.org

Kana bundu richigona kuvhiyiwa, tarisiro yacho yakanaka kune zvakanaka, zvinoenderana nekuti bundu rose rakabviswa here.

Dambudziko rakakomba kupofomara. Izvi zvinogona kuitika kana tsinga yemaziso ikakuvara zvakanyanya.

Bundu kana kubviswa kwaro kunogona kukonzera kusaenzana kwehomoni kweupenyu hwese. Mahormone akanganiswa angangoda kutsiviwa, uye ungangoda kutora mushonga kweupenyu hwako hwese.

Mamota nekuvhiyiwa dzimwe nguva zvinogona kukuvadza iyo yepashure pituitary (kumashure kwechikamu chegland). Izvi zvinogona kutungamira kuchirwere cheshuga insipidus, mamiriro ane zviratidzo zvekugara uchimbirwa uye nyota yakanyanyisa.

Fonera mupiki wako kana iwe ukagadzira chero zviratidzo zvebundu repituitary.

Tumor - pituitary; Pituitary adenoma

• Endocrine masero
• Pituitary shwanu

Dorsey JF, Salinas RD, Dang M, et al. Gomarara repakati tsinga. Mune: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. Abeloff's Clinical Oncology. 6th ed. Philadelphia, PA: Elsevier; 2020: chits. 63.

Melmed S, Kleinberg D. Masango epituitary uye mamota. Mune: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Chinyorwa cheEndocrinology. 13 ed. Philadelphia, PA: Elsevier; 2016: chits. 9.