Kufambira mberi supranuclear palsy

Progressive supranuclear palsy (PSP) chirwere chekufamba chinoitika kubva mukukuvara kune mamwe maseru etsinga muuropi.

PSP mamiriro ezvinhu anokonzera zviratidzo zvakafanana nezvirwere zvePasinson.

Inosanganisira kukanganisa kumasero mazhinji europi. Nzvimbo zhinji dzinokanganiswa, kusanganisira chikamu chehuropi uko masero anodzora kufamba kwemaziso aripo. Iyo nzvimbo yehuropi iyo inodzora kudzikama kana iwe uchifamba inobatwawo. Iwo ekumberi lobes ehuropi anokanganiswawo, zvichitungamira mukuchinja kwehunhu.

Chikonzero chekukuvara kwemaseru ehuropi hachizivikanwe. PSP inowedzera kuwedzera nekufamba kwenguva.

Vanhu vane PSP vane mari muhuropi matinji anotaridzika senge anowanikwa mune vanhu vane chirwere cheAlzheimer. Iko kune kurasikirwa kwetishu munzvimbo zhinji dzehuropi uye mune mamwe mativi emuzongoza.

Dambudziko iri rinowanzoonekwa muvanhu vanopfuura makore makumi matanhatu, uye rakajairika muvarume.

Zviratidzo zvinogona kusanganisira chero zvinotevera:

• Kurasikirwa kwekuyera, kudzokorora kudonha
• Kusungirirwa kumberi kana uchifamba, kana kukurumidza kufamba
• Kubondera muzviro kana vanhu
• Shanduko mumatauriro echiso
• Yakadzika mutsetse kumeso
• Matambudziko eziso uye ekuona senge vadzidzi vakasiyana saizi, kunetsekana kufambisa maziso (supranuclear ophthalmoplegia), kushaya simba pamusoro pemeso, matambudziko kuchengeta maziso akavhurika
• Zvakaoma kumedza
• Kudedera, shaya kana kumeso kumeso kana kupenga
• Hunyoro-ku-zvine mwero dementia
• Unhu hunochinja
• Zvishoma nezvishoma kana kuomarara kufamba
• Matambudziko ekutaura, akadai seakaderera izwi vhoriyamu, asingakwanise kutaura mazwi zvakajeka, anononoka kutaura
• Kuomarara uye kufamba kwakasimba mumutsipa, pakati pemuviri, maoko, nemakumbo

Kuongororwa kwenzira (kuongororwa neurologic) kunogona kuratidza:

• Dementia iri kuwedzera kuipa
• Kunetsa kufamba
• Kufamba kwemaziso mashoma, kunyanya kumusoro uye pasi kufamba
• Kuona chaiko, kunzwa, kunzwa, uye kutonga kwekufamba
• Mafambiro akaomarara uye asina kubatana seaya echirwere chePasinson

Anopa hutano anogona kuita bvunzo dzinotevera kutonga kunze kwezvimwe zvirwere:

• Magnetic resonance imaging (MRI) inogona kuratidza kudzikira kweiyo brainstem (hummingbird chiratidzo)
• PET scan yehuropi icharatidza shanduko pamberi pehuropi

Chinangwa chekurapa ndechekudzora zviratidzo. Iko hakuna kurapwa kunozivikanwa kwePSP.

Mishonga yakadai selevodopa inogona kuyedzwa. Iyi mishonga inokwidza mwero wekemikari yeuropi inonzi dopamine. Dopamine inobatanidzwa mukutonga kwekufamba. Iyo mishonga inogona kudzikamisa zvimwe zviratidzo, senge makumbo akaomarara kana kufamba kunononoka kwechinguva. Asi ivo kazhinji havana kunyatsoita sezvazviri kune chirwere chePasinson.

Vanhu vazhinji vane PSP vanozopedzisira voda kutenderera-wachi-wachi uye kutarisa sezvavanorasikirwa nehuropi mabasa.

Kurapa dzimwe nguva kunogona kudzikisa zviratidzo kwechinguva, asi mamiriro acho anozowedzera. Basa rehuropi richaderera nekufamba kwenguva. Rufu runowanzoitika mumakore mashanu kusvika manomwe.

Mishonga mitsva iri kuongororwa kuti irape mamiriro aya.

Zvinetso zvePSP zvinosanganisira:

• Ropa rakavhara mutsinga (yakadzika vein thrombosis) nekuda kwekufamba kushoma
• Kukuvara kubva kudonha
• Kusava nekutonga pamusoro pekuona
• Kurasikirwa kwehuropi kunoshanda nekufamba kwenguva
• Mabayo nekuda kwedambudziko kumedza
• Kusadya zvakanaka (kushaya zvinovaka muviri)
• Zvimwe zvinokanganisa kubva kumishonga

Fonera waunopa kana iwe uchiwanzowira, uye kana uine mutsipa wakaomarara / muviri, uye matambudziko ekuona.

Zvakare, fonera kana mudiwa akaonekwa aine PSP uye mamiriro acho aramba zvakanyanya zvekuti hauchakwanise kutarisira munhu ari pamba.

Dementia - nuchal dystonia; Richardson-Steele-Olszewski chirwere; Palsy - inofambira mberi supranuclear

• Central nervous system uye yekumusoro tsinga system

Jankovic J. Parkinson chirwere uye zvimwe zvinetso zvekufamba. Mune: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology muClinical Dzidzira. 7th ed. Philadelphia, PA: Elsevier; 2016: chits. 96.

Ling H. Clinical nzira yekufambira mberi supranuclear palsy. J Mov Kusagadzikana. 2016; 9 (1): 3-13. PMID: 26828211 pubmed.ncbi.nlm.nih.gov/26828211/.

National Institute yeNeurological Dambudziko webhusaiti. Progressive supranuclear palsy chokwadi pepa. www.ninds.nih.gov/Disorders/Patient-Caregiver-Education/Fact-Sheets/Progressive-Supranuclear-Palsy-Fact-Sheet. Yakagadziridzwa Kurume 17, 2020. Yakasvika Nyamavhuvhu 19, 2020.