Skeletal limb kusagadzikana

Skeletal limb kusanzwisisika kunoreva kwakasiyana-siyana kwematambudziko echimiro chemapfupa mumaoko kana makumbo.

Izwi rekuti maronda emakumbo emakumbo rinowanzo shandiswa kutsanangura hurema mumakumbo kana maoko anokonzerwa nedambudziko nemajini kana ma chromosomes, kana izvo zvinoitika nekuda kwechiitiko chinoitika panguva yekuzvitakura.

Izvo zvakashata zvinowanzo kuve zviripo pakuzvara.

Zviremara zvemakumbo zvinogona kukura mushure mekuzvarwa kana munhu aine mariketi kana zvimwe zvirwere zvinokanganisa chimiro chemapfupa.

Skeletal limb kukanganisika kungave kuri nekuda kwechero yeanotevera:

• Gomarara
• Zvirwere zveGenetic uye chromosomal zvisizvo, kusanganisira Marfan syndrome, Down syndrome, Apert syndrome, uye Basal cell nevus syndrome
• Nzvimbo isina kufanira mudumbu
• Zvirwere panguva yekuzvitakura
• Kukuvadza panguva yekuzvarwa
• Kushaya zvokudya zvinovaka muviri
• Matambudziko emetabolism
• Matambudziko epamuviri, kusanganisira kukamurwa kwemaoko kubva kuamniotic band kukanganiswa kuteedzana
• Kushandiswa kwemimwe mishonga panguva yekuzvitakura inosanganisira thalidomide, iyo inokonzeresa chikamu chepamusoro chemaoko kana makumbo kushayikwa, uye aminopterin, izvo zvinotungamira mukushomeka kweruoko

Fonera wako mupi wehutano kana iwe uine chero zvinonetsa nezvehurefu hwemakumbo kana chitarisiko.

Mucheche ane mitezo isina kujairika anowanzove nezvimwe zviratidzo nezviratidzo izvo, kana zvatorwa pamwechete, zvinotsanangura chakati chirwere kana mamiriro kana kupa chirevo chechakakonzera kusagadzikana. Kuongororwa kunoenderana nenyaya yemhuri, nhoroondo yezvokurapa, uye kunyatsoongorora muviri.

Chiremba nhoroondo mibvunzo inogona kusanganisira:

• Pane chero munhu mumhuri yako ane mafupa akaremara?
• Paive paine matambudziko panguva yepamuviri?
• Ndeapi madhiragi kana mishonga yakatorwa panguva yekuzvitakura?
• Ndezvipi zvimwe zviratidzo kana zvisizvo zviripo?

Mimwe bvunzo senge chromosome zvidzidzo, enzyme assays, x-rays, uye metabolic zvidzidzo zvinogona kuitwa.

Deeney VF, Arnold J. Orthopedics. Mune: Zitelli BJ, McIntire SC, Nowalk AJ, eds. Zitelli naDavis 'Atlas yePediatric Panyama Kuongorora. 7th ed. Philadelphia, PA: Elsevier; 2018: chitsiko 22.

Herring JA. Skeletal dysplasias. Mune: Herring JA, ed. Tachdjian's Pediatric Orthopedics. 6th ed. Philadelphia, PA: Elsevier; 2022: chitsauko 36.

McCandless SE, Kripps KA. Genetics, zvikanganiso zvekuzvarwa kwemetabolism, uye kuongororwa kwevana vachangozvarwa. Mune: Fanaroff AA, Fanaroff JM, eds. Klaus naFanaroff Kuchengeta kweiyo Yakakwira Njodzi Neonate. 7th ed. Philadelphia, PA: Elsevier; 2020: chits.