Therapeutic drug levels

Marapirwo ekurapa madhiragi ndiwo mabvunzo ekurapa kutsvaga huwandu hwemushonga muropa.

Muenzaniso weropa unodiwa. Kazhinji yenguva ropa rinotorwa kubva mutsinga iri mukati megokora kana kuseri kweruoko.

Iwe unozofanirwa kugadzirira kumwe bvunzo dzezvinodhaka.

• Anokuchengetedza hutano anokuudza kana iwe uchida kushandura nguva dzaunotora chero yemimwe mishonga yako.
• Usamise kana kushandura mishonga yako usati wataura nemupi wako kutanga.

Unogona kunzwa kurwadziwa kushoma kana kurumwa kana tsono yaiswa. Iwe unogona zvakare kunzwa kumwe kurovera panzvimbo iyi mushure mekudhonzwa kweropa.

Nemishonga yakawanda, iwe unoda imwe nhanho yemushonga muropa rako kuti uwane mhedzisiro. Mimwe mishonga inokuvadza kana mwero ukakwira zvakanyanya uye usingashande kana iwo mwero wakadzika zvakanyanya.

Kuongorora huwandu hwemushonga unowanikwa muropa rako unobvumidza mupi wako kuona kuti mwero wezvinodhaka uri munzvimbo chaiyo.

Kuongororwa kwezvinodhaka kwakakosha kune vanhu vanotora zvinodhaka zvakadai se:

• Flecainide, procainamide kana digoxin, ayo anoshandiswa kurapa zvisina kujairika kurova kwemoyo
• Lithium, inoshandiswa kurapa bipolar kusagadzikana
• Phenytoin kana valproic acid, ayo anoshandiswa kurapa pfari
• Gentamicin kana amikacin, ayo ari maantibayoti anoshandiswa kurapa hutachiona

Kuedzwa kunogona kuitwawo kuti uone kuti muviri wako unoputsa sei mushonga wacho kana kuti unobatana sei nemimwe mishonga yaunoda.

Kutevera ndeimwe yemishonga inowanzo kuongororwa uye zvakajairwa nhanho nhanho:

• Acetaminophen: inosiyana nekushandisa
• Amikacin: 15 kusvika 25 mcg / mL (25.62 kusvika 42.70 micromol / L)
• Amitriptyline: 120 kusvika 150 ng / mL (432.60 kusvika 540.75 nmol / L)
• Carbamazepine: 5 kusvika 12 mcg / mL (21.16 kusvika 50.80 micromol / L)
• Cyclosporine: 100 kusvika 400 ng / mL (83.20 kusvika 332.80 nmol / L) (maawa gumi nemaviri mushure meyero)
• Desipramine: 150 kusvika 300 ng / mL (563.10 kusvika 1126.20 nmol / L)
• Digoxin: 0.8 kusvika 2.0 ng / mL (1.02 kusvika 2.56 nanomol / L)
• Disopyramide: 2 kusvika 5 mcg / mL (5.89 kusvika 14.73 micromol / L)
• Ethosuximide: 40 kusvika 100 mcg / mL (283.36 kusvika 708.40 micromol / L)
• Flecainide: 0.2 kusvika 1.0 mcg / mL (0.5 kusvika 2.4 micromol / L)
• Gentamicin: 5 kusvika 10 mcg / mL (10.45 kusvika 20.90 micromol / L)
• Imipramine: 150 kusvika 300 ng / mL (534.90 kusvika 1069.80 nmol / L)
• Kanamycin: 20 kusvika 25 mcg / mL (41.60 kusvika 52.00 micromol / L)
• Lidocaine: 1.5 kusvika 5.0 mcg / mL (6.40 kusvika 21.34 micromol / L)
• Lithium: 0.8 kusvika 1.2 mEq / L (0.8 kusvika 1.2 mmol / L)
• Methotrexate: inosiyana nekushandisa
• Nortriptyline: 50 kusvika 150 ng / mL (189.85 kusvika 569.55 nmol / L)
• Phenobarbital: 10 kusvika 30 mcg / mL (43.10 kusvika 129.30 micromol / L)
• Phenytoin: 10 kusvika 20 mcg / mL (39.68 kusvika 79.36 micromol / L)
• Primidone: 5 kusvika 12 mcg / mL (22.91 kusvika 54.98 micromol / L)
• Procainamide: 4 kusvika 10 mcg / mL (17.00 kusvika 42.50 micromol / L)
• Quinidine: 2 kusvika 5 mcg / mL (6.16 kusvika 15.41 micromol / L)
• Salicylate: inosiyana nekushandisa
• Sirolimus: 4 kusvika 20 ng / mL (4 kusvika 22 nmol / L) (maawa gumi nemaviri mushure meyero; inosiyana nekushandisa)
• Tacrolimus: 5 kusvika 15 ng / mL (4 kusvika 25 nmol / L) (maawa gumi nemaviri mushure mekuita)
• Theophylline: 10 kusvika 20 mcg / mL (55.50 kusvika 111.00 micromol / L)
• Tobramycin: 5 kusvika 10 mcg / mL (10.69 kusvika 21.39 micromol / L)
• Valproic acid: 50 kusvika 100 mcg / mL (346.70 kusvika 693.40 micromol / L)

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Taura nemupi wako nezve zvinorehwa nemimwe miedzo yako.

Iyi mienzaniso iripamusoro inoratidza zviyero zvakajairika zvemhedzisiro yeiyi bvunzo. Mamwe marabhoritari anoshandisa zviyero zvakasiyana kana anogona kuyedza mienzaniso dzakasiyana.

Maitiro ari kunze kwenzvimbo yakatarwa anogona kunge achikonzerwa neshanduko diki kana kuve chiratidzo chekuti iwe unofanirwa kugadzirisa madosi ako. Mubatsiri wako anogona kukuudza kuti usvetuke dose kana zviyero zvakayerwa zvakakwirira kwazvo.

Zvinotevera zvine huturu hweimwe yemishonga inowanzo kuongororwa:

• Acetaminophen: yakakura kupfuura 250 mcg / mL (1653.50 micromol / L)
• Amikacin: yakakura kupfuura 25 mcg / mL (42.70 micromol / L)
• Amitriptyline: yakakura kupfuura mazana 500 ng / mL (1802.50 nmol / L)
• Carbamazepine: yakakura kudarika 12 mcg / mL (50.80 micromol / L)
• Cyclosporine: yakakura kupfuura 400 ng / mL (332.80 micromol / L)
• Desipramine: yakakura kupfuura mazana 500 ng / mL (1877.00 nmol / L)
• Digoxin: yakakura kupfuura 2.4 ng / mL (3.07 nmol / L)
• Disopyramide: yakakura kupfuura 5 mcg / mL (14.73 micromol / L)
• Ethosuximide: yakakura kupfuura 100 mcg / mL (708.40 micromol / L)
• Flecainide: yakakura kupfuura 1.0 mcg / mL (2.4 micromol / L)
• Gentamicin: yakakura kupfuura gumi nemaviri mcg / mL (25.08 micromol / L)
• Imipramine: yakakura kupfuura 500 ng / mL (1783.00 nmol / L)
• Kanamycin: yakakura kupfuura 35 mcg / mL (72.80 micromol / L)
• Lidocaine: yakakura kupfuura 5 mcg / mL (21.34 micromol / L)
• Lithium: yakakura kupfuura 2.0 mEq / L (2.00 millimol / L)
• Methotrexate: yakakura kupfuura gumi mcmol / L (10,000 nmol / L) pamusoro pe24-maawa
• Nortriptyline: yakakura kupfuura 500 ng / mL (1898.50 nmol / L)
• Phenobarbital: yakakura kupfuura 40 mcg / mL (172.40 micromol / L)
• Phenytoin: yakakura kupfuura 30 mcg / mL (119.04 micromol / L)
• Primidone: yakakura kupfuura 15 mcg / mL (68.73 micromol / L)
• Procainamide: yakakura kupfuura 16 mcg / mL (68.00 micromol / L)
• Quinidine: yakakura kupfuura gumi mcg / mL (30.82 micromol / L)
• Salicylate: yakakura kupfuura 300 mcg / mL (2172.00 micromol / L)
• Theophylline: yakakura kupfuura makumi maviri emamirg / mL (111.00 micromol / L)
• Tobramycin: yakakura kupfuura 12 mcg / mL (25.67 micromol / L)
• Valproic acid: yakakura kupfuura 100 mcg / mL (693.40 micromol / L)

Kurapa kwekutarisa zvinodhaka

• Kuongorora ropa

Clarke W. Ongororo yekurapa kwekutarisa zvinodhaka. Mune: Clarke W, Dasgupta A, eds. Clinical Zvinetso muKurapa Kwemishonga Kuongorora. Cambridge, MA: Elsevier; 2016: chits 1.

Diasio RB. Nheyo dzekurapa zvinodhaka. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chitsiko 29.

Nelson LS, Ford MD. Huturu hwakanyanya. Mune: Goldman L, Schafer AI, eds. Goldman-Cecil Mushonga. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016: chits. 110.

Pincus MR, Bluth MH, Abraham NZ. Toxicology uye yekurapa kwekutarisa zvinodhaka. Mune: McPherson RA, Pincus MR, eds. Henry's Clinical Diagnosis uye Management nemaLabhoritari Maitiro. 23rd ed. St Louis, MO: Elsevier; 2017: chitsiko 23.