Cortisol kuongororwa kweropa

Iko cortisol yeropa bvunzo inoyera chiyero checortisol muropa. Cortisol is steroid (glucocorticoid kana corticosteroid) hormone inogadzirwa neadrenal gland.

Cortisol inogona kuyerwa zvakare uchishandisa weti kana saliva bvunzo.

Muenzaniso weropa unodiwa.

Chiremba wako angangoita kuti iwe uite bvunzo mangwanani-ngwanani. Izvi zvakakosha, nekuti chikamu checortisol chinosiyana zuva rese.

Iwe unogona kukumbirwa kuti usaite chero nesimba rekurovedza muviri zuva risati ratongwa.

Iwe unogona zvakare kuudzwa kuti umbomira kutora mishonga inogona kukanganisa bvunzo, kusanganisira:

• Mishonga yekudzivirira kubata
• Estrogen
• Yakagadzirwa nevanhu (synthetic) glucocorticoids, senge hydrocortisone, prednisone uye prednisolone
• Androgens

Kana tsono ikaiswa kukweva ropa, vamwe vanhu vanonzwa kurwadziwa zvine mwero. Vamwe vanongonzwa kubaya kana kubaya. Mushure meizvozvo, panogona kuve nekurohwa kana kupwanya zvishoma. Izvi zvinokurumidza kuenda.

Chiyero chinoitwa kutarisa kuwedzerwa kana kudzikira kwecortisol kugadzirwa. Cortisol iglucocorticoid (steroid) hormone yakaburitswa kubva kune adrenal gland mukupindura kune adrenocorticotropic hormone (ACTH). ACTH ihormone inoburitswa kubva pituitary gland muuropi.

Cortisol inokanganisa masisitimu mazhinji emuviri. Inoita basa mu:

• Kukura kwepfupa
• Ropa rekumanikidza kutonga
• Immune system inoshanda
• Metabolism yemafuta, makabhohaidhiretsi, uye mapuroteni
• Kutya system inoshanda
• Kushungurudzika kupindura

Zvirwere zvakasiyana, senge Cushing syndrome uye Addison chirwere, zvinogona kutungamira kune yakawandisa kana kushoma kugadzirwa kwecortisol. Kuyera ropa cortisol level kunogona kubatsira kuongorora aya mamiriro. Izvo zvakare zvinoyerwa kuongorora kuti mashandiro epituitary uye adrenal anoshanda sei.

Chiyero chinowanzoitwa pamberi uye 1 awa mushure mekubayiwa kwemushonga unonzi ACTH (cosyntropin). Ichi chikamu chemuedzo chinonzi ACTH kukurudzira bvunzo. Icho chiitiko chakakosha chinobatsira kutarisa mashandiro epituitary uye adrenal gland.

Mimwe mamiriro ezvinhu ayo muyedzo unogona kurairwa unosanganisira:

• Acute adrenal dambudziko, hupenyu hunotyisidzira hupenyu hunoitika kana pasina kukwana cortisol yakakwana
• Sepsis, chirwere umo muviri une mhinduro yakasimba kubhakitiriya kana mamwe majemusi
• Kuderera kweropa

Maitiro akajairwa muyero weropa wakatorwa na8 mangwanani ndewe5 kusvika 25 mcg / dL kana 140 kusvika 690 nmol / L.

Maitiro akajairwa anoenderana nenguva yezuva uye mamiriro echipatara. Zvikamu zvakajairika zvinogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Mamwe marabhoritari anoshandisa zviyero zvakasiyana kana anogona kuyedza mhando dzakasiyana. Taura nachiremba wako nezve zvinorehwa nemimwe miedzo yako.

Iyo yepamusoro kupfuura yakajairwa nhanho inogona kuratidza:

• Cushing chirwere, mune iyo pituitary gland inogadzira yakawandisa ACTH nekuda kwekuwedzera kukura kwepituitary gland kana bundu mune iyo pituitary gland.
• Ectopic Cushing syndrome, umo bundu riri kunze kwepituitary kana adrenal glands rinoita zvakanyanya ACTH
• Tumor yeadrenal gland iri kuburitsa yakawandisa cortisol
• Kushungurudzika
• Kurwara kwakanyanya

Iyo yakaderera pane yakajairwa nhanho inogona kuratidza:

• Chirwere cheAddison, umo maronda adrenal haaburitse yakakwana cortisol
• Hypopituitarism, umo pituitary gland haina kuratidza iyo adrenal gland kuburitsa yakakwana cortisol
• Kudzvinyirira kweyakajairwa pituitary kana adrenal basa nemishonga yeglucocorticoid inosanganisira mapiritsi, mafuta eganda, eyedrops, inhalers, majekiseni majoini, chemotherapy

Pane njodzi shoma inosanganisirwa nekutorwa kweropa rako. Tsinga uye tsinga zvinosiyana muhukuru kubva kumunhu kuenda kune mumwe uye kubva kune rimwe divi remuviri kuenda kune rimwe. Kutora ropa kubva kune vamwe vanhu kunogona kunge kwakaoma kupfuura kubva kune vamwe.

Dzimwe njodzi dzinosangana nekutorwa kweropa idiki, asi dzinogona kusanganisira:

• Kuwedzera kubuda ropa
• Kufenda kana kunzwa kushaya musoro
• Akawanda punctures ekutsvaga mutsinga
• Hematoma (ropa rinoungana pasi peganda)
• Utachiona (hushoma njodzi chero nguva ganda parinovhunika)

Serum cortisol

Chernecky CC, Berger BJ. Cortisol - plasma kana serum. Mune: Chernecky CC, Berger BJ, eds. Rabhoritari Kuyedza uye Maitiro Ekuongorora. 6th ed. St Louis, MO: Elsevier Saunders; 2013: 388-389.

Stewart PM, Newell-Mutengo JDC. Iyo adrenal cortex. Mune: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. Williams Chinyorwa cheEndocrinology. 13 ed. Philadelphia, PA: Elsevier; 2016: chits.