Bilirubin encephalopathy

Bilirubin encephalopathy chinhu chisingawanzoitika chetsinga chinowanikwa mune vamwe vacheche vane chirwere chakakomba chendundundu.

Bilirubin encephalopathy (BE) inokonzerwa nematanho akakwirira kwazvo ebilirubin. Bilirubin yero pigment iyo inogadzirwa sezvo muviri unobvisa masero matsvuku eropa. Mahombekombe epamusoro ebilirubin mumuviri anogona kukonzera ganda kutaridzika yero (jaundice).

Kana huwandu hwebilirubin hwakanyanya kana mwana achinge achirwara zvakanyanya, chinhu chinobuda muropa uye chinounganidza munyama yehuropi kana chisina kusungirwa kualbumin (protein) muropa. Izvi zvinogona kutungamira kumatambudziko akadai sekukuvara kwehuropi uye kurasikirwa kwekunzwa. Izwi rekuti "kernicterus" rinoreva kusvibiswa kweruvara kunokonzerwa nebilirubin. Izvi zvinoonekwa muzvikamu zvehuropi pakuongororwa.

Aya mamiriro anowanzo kukura muvhiki yekutanga yehupenyu, asi anogona kuoneka kumusoro kusvika pavhiki rechitatu. Vamwe vacheche vane Rh hemolytic chirwere vari panjodzi yakakura yejundice yakaoma iyo inogona kutungamira kune ino mamiriro. Kazhinji, BE inogona kukura mune zvinoita sevana vane hutano.

Zviratidzo zvinoenderana nedanho reBE. Havasi vese vacheche vane kernicterus pane autopsy vane chaiwo zviratidzo.

Pakutanga nhanho:

• Yakanyanya jaundice
• Kushamisika kunovhundutsa
• Kudya zvakashata kana kuyamwa
• Kunyanya kurara (kuneta) uye yakaderera mhasuru toni (hypotonia)

Pakati pepakati:

• Kuchema kwepamusoro
• Kushatirwa
• Angangodaro arched kumashure nemutsipa hyperextended kumashure, yakakwira mhasuru toni (hypertonia)
• Kudya zvisina tsarukano

Nguva yekupedzisira:

• Stupor kana coma
• Hapana kudyisa
• Shrill kuchema
• Tsinga kuomarara, yakanyatso arched kumashure nemutsipa hyperextended kumashure
• Kufenda

Kuongororwa kweropa kucharatidza yakakwira bilirubin nhanho (yakakura kupfuura makumi maviri kusvika makumi maviri nemashanu mg / dL). Nekudaro, hapana hukama chaihwo pakati peiri bilirubin uye mwero wekukuvara.

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Taura nachiremba wako nezve zvinorehwa nemimwe miedzo yako.

Kurapa kunoenderana nekuti mwana ane makore mangani (mumaawa) uye kuti mwana ane njodzi here (senge prematurity). Inogona kusanganisira:

• Chiedza chemwenje (phototherapy)
• Chinjana kuwedzerwa (kubvisa ropa remwana uye kuritsiva neropa rinopa mutsva kana plasma)

BE chinzvimbo chakakomba. Vazhinji vacheche vane yekupedzisira-danho rehurongwa hwematambudziko vanofa.

Zvinetso zvinogona kusanganisira:

• Kukuvara kwehuropi zvachose
• Kunzwa kurasikirwa
• Rufu

Tora rubatsiro rwechiremba ipapo ipapo kana mwana wako aine zviratidzo zveichi chiitiko.

Kurapa jaundice kana mamiriro anogona kutungamira kwairi kunogona kubatsira kudzivirira dambudziko iri. Vacheche vane zviratidzo zvekutanga zvejaundice vane bilirubin level yakayerwa mukati memaawa makumi maviri nemana. Kana mwero wakakwira, mucheche anofanira kuongororwa zvirwere zvinosanganisira kuparadzwa kwemasero matsvuku eropa (hemolysis).

Vese vachangozvarwa vane musangano wekutevera mukati memazuva maviri kusvika matatu vabuda muchipatara. Izvi zvakakosha zvakanyanya kunonoka kutangira kana yekutanga nguva vacheche (vanozvarwa anopfuura mavhiki maviri kusvika matatu zuva ravo risati rasvika).

Bilirubin-inosimudzira neurologic kusagadzikana (BIND); Kernicterus

• Achangoberekwa jaundice - buditsa

• Kernicterus

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