Cobicistat

Zvemukati

• Usati watora cobicistat,
• Cobicistat inogona kukonzera mhedzisiro. Udza chiremba wako kana chiratidzo ichi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

Cobicistat inoshandiswa kuwedzera huwandu hweatazanavir (Reyataz, muEvotaz) muvanhu vakuru nevana vanorema angangoita makirogiramu makumi matatu nemashanu kana makumi matatu (35 kg) kana darunavir (Prezista, muPrezcixix) muvakuru nevana vanorema angangoita mapaundi 88 (40 kg) mu ropa apo mishonga iyi inoshandiswa kurapa hutachiona hwehutachiona hwehutachiona hweHIV (HIV). Cobicistat iri mukirasi yemishonga inonzi cytochrome P450 3A (CYP3A) inhibitors. Inoshanda nekuwedzera huwandu hweatazanavir kana darunavir mumuviri kuitira kuti vagone kuve nemhedzisiro huru.

Cobicistat inouya sehwendefa kutora nemuromo. Inowanzo kutorwa nechikafu kamwe chete pazuva pamwe neatazanavir kana darunavir. Tora cobicistat neatazanavir kana darunavir panguva yakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora cobicistat chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Izvo zvakakosha kuti ugare uchitora cobicistat panguva imwechete seatazanavir kana darunavir.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora cobicistat,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune cobicistat, chero mimwe mishonga, kana chero chipi zvacho chemapiritsi ecobicistat. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako kana iwe uri kutora chero einotevera mishonga: alfuzosin (Uroxatral); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol); cisapride (Propulsid) (haisipo muU.S.); colchicine (Colcrys, Mitigare, muCol-Probenecid); dronedarone (Multaq); ergot mishonga yakadai se dihydroergotamine (DHE 45, Migranal), ergotamine (Ergomar, muCafergot, muMigergot), uye methylergonovine (Methergine); lomitapide (Juxtapid); lovastatin (Altoprev); lurasidone (Latuda); midazolam (Ndima) nemuromo; phenobarbital; phenytoin (Dilantin, Phenytek); pimozide (Orap); ranolazine (Ranexa); rifampin (Rimactane, Rifadin, muRifamate, muRifater); sildenafil (chete Revatio brand inoshandiswa pachirwere chemapapu); simvastatin (Flolipid, Zocor); Wort St. kana triazolam (Halcion). Kana iwe uri kutora atazanavir pamwe necobicistat, udza chiremba wako kana iwe uri kutora drospirenone uye ethinyl estradiol (mamwe emumuromo ekudzivirira kubata pamuviri akadai saBeyaz, Safyral, Yasmin, Yaz, mamwe); indinavir (Crixivan), irinotecan (Camptosar), kana nevirapine (Viramune). Chiremba wako angangokuudza kuti usatore cobicistat kana iwe uri kutora chero eiyi mishonga.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: anticoagulants ('blood thinner') senge apixaban (Eliquis), simba powder (Bevyxxa), dabigatran (Pradaxa), edoxaban (Savaysa), rivaroxaban powder (Xarelto), uye warfarin (Coumadin, Jantoven) ; antiplatelet mishonga yakadai seclopidogrel (Plavix) uye ticagrelor (Brilinta); atorvastatin (Lipitor, muCaduet); benzodiazepines senge diazepam (Valium), estazolam, midazolam yakapihwa mukati mehasha (kupinda mutsinga), uye zolpidem (Ambien, Edluar, Intermezzo); beta blockers senge carvedilol (Coreg), metoprolol (Lopressor), uye timolol; boceprevir (Victrelis) (haisipo muU.S.); bosentan (Tracleer); buprenorphine (Belbuca, Butrans, Probuphine); buprenorphine uye naloxone (Suboxone, Zubsolv); buspirone; calcium chiteshi blockers senge amlodipine (Norvasc), diltiazem (Cardizem, Cartia, Tiazac, vamwe), felodipine, nifedipine (Adalat, Afeditab, Procardia), uye verapamil (Calan, Verelan, vamwe); clarithromycin (Biaxin, muPrevPac); corticosteroids yakadai beclomethasone (Beconase AQ), budesonide (Rhinocort Aqua), ciclesonide (Omnaris), dexamethasone (Decadron), fluticasone (Flonase, Flovent), methylprednisolone (Medrol), momentasone (Flonase), uye triamcinolone (Nasacort) dasatinib (Sprycel); efavirenz (Sustiva, muAtripla); erythromycin (E.E.S, Erytab, vamwe); etravirine (kusagadzikana); fentanyl (Abstral, Actiq, Fentora, vamwe); itraconazole (Onmel, Sporanox); ketoconazole; mishonga yekushungurudzika senge amitriptyline, desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Brisdelle, Paxil, Pexeva), uye trazodone; mishonga yekushaya moyo zvisina kujairika senge amiodarone (Cordarone, Nexterone, Pacerone), digoxin (Lanoxin), disopyramide (Norpace), flecainide, mexiletine, propafenone (Rythmol), uye quinidine (muNuedexta); mishonga yekubatwa kwakadai seclonazepam (Klonopin), eslicarbazepine (Aptiom), uye oxcarbazepine (Trileptal); mishonga inodzvinyirira immune system se cyclosporine (Gengraf, Neoral, Sandimmune), everolimus (Afinitor, Zortress), sirolimus (Rapamune), uye tacrolimus (Astagraf, Envarsus XR, Prograf); lopinavir (muKaletra); maraviroc (Selzentry); methadone (Dolophine, Methadose); nilotinib (Tasigna); mishonga yekudzivirira pamuromo (mapiritsi ekudzivirira kubereka); perphenazine; zvimwe phosphodiesterase (PDE5) inhibitors senge avanafil (Stendra), sildenafil (Viagra), tadalafil (Adcirca, Cialis), uye vardenafil (Levitra); quetiapine (Seroquel); rifabutin (Mycobutin); risperidone (Risperdal); ritonavir (Norvir, muKaletra); rivaroxaban powder (Xarelto); rosuvastatin; salmeterol (Serevent, muAdvair); simeprevir (Olysio); telaprevir (Incivek) (haiwanikwe muU.S.); telithromycin (Ketek); tenofovir (Viread, muAtripla, Complera, Truvada, vamwe), thioridazine; tramadol (Conzip, Ultram, mu Ultracet); vinblastine; vincristine (Marqibo Kit); uye voriconazole (Vfend). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana necobicistat saka ive shuwa yekuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• kana iwe uri kutora cobicistat neatazanavir uye urikutorawo antacids (Maalox, Mylanta, Tums, vamwe), tora iwo maawa maviri pamberi kana maviri maawa mushure mecobicistat uye atazanavir.
• kana iwe uri kutora cobicistat neatazanavir uye urikutorawo mushonga wekugaya, kuora moyo, kana maronda (H₂ blockers) senge cimetidine, famotidine (Pepcid, muAxxis), nizatidine (Axid), kana ranitidine (Zantac), tora ivo panguva imwechete kana angangoita maawa gumi mushure mekutora H₂ blocker.
• kana uri kutora cobicistat neatazanavir uye urikutorawo mushonga wekugaya, kuora moyo, kana maronda (proton pump inhibitors) senge esomeprazole (Nexium, muVimovo), lansoprazole (Prevacid), omeprazole (Prilosec, muZegerid), pantoprazole (Protonix), kana rabeprazole (AcipHex) inotora iwo angangoita maawa gumi nemaviri mushure mekutora proton pump inhibitor.
• udza chiremba wako kana iwe wakambove kana uine chirwere cheitsvo kana chiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora cobicistat, fonera chiremba wako. Iwe haufanire kuyamwa kana uine hutachiwana hweHIV kana kana uri kutora cobicistat.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Kana yako inotevera dosi inokodzera mumaawa gumi nemaviri kana kupfuura, tora iyo yakarasika dhizai nekukurumidza kana uchinge uchayeuka izvozvo. Nekudaro, kana iyo inotevera dhizaini ichatorwa mune asingasviki maawa gumi nemaviri, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Cobicistat inogona kukonzera mhedzisiro. Udza chiremba wako kana chiratidzo ichi chakanyanya kana kuti chisingaendi:

• kusvotwa

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

• yero yeganda kana maziso
• mapundu
• kuderera kwekuita weti

Cobicistat inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo pamhepo pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari ekuongorora usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune cobicistat.

Chengeta kupihwa kwemishonga paruoko. Usamirira kusvikira iwe wapererwa nemushonga kuti uzorodze tsamba yako.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Tybost^®

• Evotaz^® (iine Atazanavir, Cobicistat)
• Prezcobix^® (iine Cobicistat, Darunavir)