Quadruple skrini bvunzo

Iyo quadruple skrini bvunzo kuongorora kweropa kunoitwa panguva yekuzvitakura kuti uone kana mwana ari panjodzi yekumwe kuremara kwekuzvarwa.

Muedzo uyu unowanzoitwa pakati pemasvondo gumi nemashanu kusvika makumi maviri nemaviri ekubata pamuviri. Iyo yakanyatsojeka pakati pevhiki regumi nesere negumi nemasere.

Muenzaniso weropa unotorwa woendeswa kubazi kunoongororwa.

Iyo bvunzo inoyera matanho e4 mimba nhumbu.

• Alpha-fetoprotein (AFP), puroteni inogadzirwa nemwana
• Chorionic gonadotropin (hCG) yemunhu, kemikari inogadzirwa muplacenta
• Unconjugated estriol (uE3), chimiro chehormone estrogen inogadzirwa mu "fetus" uye "placenta"
• Inhibin A, hormone yakaburitswa nepacenta

Kana iyo bvunzo ikasayera nhanho dze inhibin A, inonzi iyo katatu skrini bvunzo.

Kuti uone mukana wekuti mwana wako ave nehurema hwekuzvarwa, iyo bvunzo zvakare inokonzeresa mu:

• Zera rako
• Dzinza rako
• Kurema kwako
• Zera remwana wako rekubata (rakayerwa mumavhiki kubva pazuva rekupedzisira kusvika kune razvino zuva)

Hapana matanho akakosha anodiwa kugadzirira bvunzo. Unogona kudya kana kunwa zvakajairika usati wayedzwa.

Unogona kunzwa kurwadziwa kushoma kana kurumwa kana tsono yaiswa. Iwe unogona zvakare kunzwa kumwe kurovera panzvimbo iyi mushure mekudhonzwa kweropa.

Muedzo unoitwa kuti uone kana mwana wako angave ari panjodzi yekumwe kuremara kwekuzvarwa, senge Down syndrome uye hurema hwekuzvarwa hwemuzongoza uye huropi (inonzi neural tube kuremara). Bvunzo iyi bvunzo yekuongorora, saka haiongorore matambudziko.

Vamwe vakadzi vari panjodzi huru yekuve nemwana ane hurema uhu, kusanganisira:

• Vakadzi vane makore anopfuura makumi matatu nemashanu panguva yekuzvitakura
• Vakadzi vanotora insulin kurapa chirwere cheshuga
• Vakadzi vane nhoroondo yemhuri yekuremara kwekuberekwa

Maitiro akajairwa eAFP, hCG, uE3, uye inhibin A.

Zvakajairika kukosha masenduru anogona kusiyana zvishoma pakati pemarabhoritari akasiyana. Taura nemupi wako wezvehutano nezve zvinorehwa nemimwe miedzo yako.

Chiitiko chisina kujairika bvunzo hazvireve kuti mwana wako ane hurema hwekuzvarwa. Kazhinji, mhedzisiro yacho inogona kunge isina kujairika kana mwana wako akura kana ari mudiki pane waakange afunga.

Kana iwe uine chisina kujairika mhedzisiro, iwe uchave uine imwe ultrasound yekutarisa zera remwana ari kukura.

Mimwe bvunzo uye kurairwa kunogona kukurudzirwa kana iyo ultrasound ikaratidza dambudziko. Nekudaro, vamwe vanhu vanosarudza kusaitazve imwe bvunzo inoitwa, nekuda kwavo kana zvikonzero zvechitendero.Anogona kuita anotevera matanho anosanganisira:

• Amniocentesis, iyo inotarisa iyo AFP mwero mune amniotic fluid yakatenderedza mwana. Kuongorora genetic kunogona kuitwa pane amniotic fluid yakabviswa bvunzo.
• Kuyedza kuona kana kutonga kunze kwehumwe hurema (senge Down syndrome).
• Genetic counselling.
• Ultrasound yekutarisa uropi hwemwana, musana, itsvo, uye moyo.

Munguva yekuzvitakura, kuwedzera kweAFP kunogona kukonzerwa nedambudziko nemwana ari kukura, kusanganisira:

• Kushaikwa kwechikamu chehuropi uye dehenya (anencephaly)
• Kukanganisa mumatumbu emwana kana dzimwe nhengo dzepedyo (senge duodenal atresia)
• Rufu rwemucheche mudumbu (kazhinji runoguma nhumbu)
• Spina bifida (musana wemusana)
• Tetralogy yeFallot (moyo hurema)
• Turner syndrome (genetic kukanganisa)

High AFP inogona zvakare kureva kuti uri kutakura anopfuura mwana mumwe chete.

Kuderera kweAFP uye estriol uye yakakwira hCG uye inhibin A inogona kunge iri nekuda kwedambudziko rakadai se:

• Down syndrome (trisomy 21)
• Edwards syndrome (trisomy 18)

Iyo quadruple skrini inogona kuve nenhema-isina uye yenhema-yakanaka mhedzisiro (kunyangwe iri yakati rebei kupfuura iyo katatu skrini). Mimwe miedzo inodiwa kuratidza mhedzisiro isina kujairika.

Kana bvunzo yacho isina kujairika, ungangoda kutaura neanopa mazano.

Quad skrini; Multiple mucherechedzo kuongorora; AFP pamwe; Triple screen bvunzo; AFP amai; MSAFP; 4-mucherechedzo skrini; Down chirwere - mana; Trisomy 21 - mana; Turner chirwere - kakapetana; Spina bifida - katatu; Tetralogy - mana; Duodenal atresia - mana; Genetic counselling - mana; Alpha-fetoprotein katatu; Chorionic gonadotropin - mana; hCG - katatu; Isina kugadziriswa estriol - kakapetana; uE3 - mana; Kubata - kane; Kuberekwa kwekuzvarwa - katatu; Quadruple mucherechedzo bvunzo; Quad bvunzo; Quadruple mucherechedzo skrini

• Quadruple skrini

ACOG Dzidzira Bulletin Nha. 162: Prenatal chirwere chekuongorora kuongororwa kwehutano hwemagetsi. Obstet Gynecol. 2016; 127 (5): e108-e122. PMID: 26938573 pubmed.ncbi.nlm.nih.gov/26938573/.

Driscoll DA, Simpson JL. Genetic screening uye prenatal genetic kuongororwa. Mune: Landon MB, Galan HL, Jauniaux ERM, et al, eds. Obstetrics yaGabbe: Yakajairika uye Dambudziko Pamuviri. 7th ed. Philadelphia, PA: Elsevier; 2021: chits.

Wapner RJ, Dugoff L. Prenatal kuongororwa kwehutano hwepamuviri. Mu: Resnik R, Lockwood CJ, Moore TR, Greene MF, Copel JA, Sirivha RM, eds. Creasy uye Resnik's Maternal-Fetal Mushonga: Misimboti uye Dzidzira. 8th ed. Philadelphia, PA: Elsevier; 2019: chitsuwa 32.

Williams DE, Pridjian G. Obstetrics. Mune: Rakel RE, Rakel DP, eds. Chinyorwa cheMhuri Mishonga. 9th ed. Philadelphia, PA: Elsevier; 2016: chitsiko 20.