Darunavir

Zvemukati

• Usati watora darunavir,
• Darunavir inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona chimwe chezviratidzo izvi, rega kutora darunavir uye udane chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira

Darunavir inoshandiswa ne ritonavir (Norvir) nemimwe mishonga yekurapa hutachiona hwehutachiona hwehutachiwana hweHIV muvanhu vakuru nevana vane makore matatu zvichikwira. Darunavir iri mukirasi yemishonga inonzi protease inhibitors. Inoshanda nekuderedza huwandu hweHIV muropa. Kunyangwe darunavir isingarape HIV, inogona kudzikisira mukana wako wekuwana immunodeficiency syndrome (AIDS) nezvirwere zvine chekuita neHIV senge hutachiona hwakakomba kana gomarara. Kutora mishonga iyi pamwe nekuita bonde rakachengeteka uye nekuita mamwe mararamire shanduko kunogona kudzora mukana wekutapurira hutachiona hweHIV kune vamwe vanhu.

Darunavir inouya sehwendefa uye kumiswa pamuromo (mvura) kutora nemuromo. Inowanzo kutorwa nechikafu uye ne ritonavir kamwe kana kaviri pazuva. Tora darunavir kwakatenderedza nguva imwechete (ma) mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora darunavir chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Usatore darunavir isina ritonavir.

Medza mapiritsi akazara nechinwiwa chakadai semvura kana mukaka. Usatsenga mahwendefa.

Zunza kumiswa zvakanaka musati mese mushandisa kusanganisa mishonga zvakaenzana. Shandisa yemuromo dosing sirinji yakauya nemushonga kuti ubvise yakaenzana chiyero chekumiswa kubva mubhodhoro. Unogona kumedza kusimiswa wakananga kubva mujekiseni. Geza jekiseni nemvura uye rega riome zvakanaka mushure mekushandisa.

Darunavir inodzora Mukondombera asi hairape. Ramba uchitora darunavir kunyangwe uchinzwa mushe. Usarega kutora darunavir usina kutaura nachiremba wako. Kana iwe ukarega kutora darunavir kana kusvetuka madosi, mamiriro ako angave akaoma zvakanyanya kurapa. Kana kupihwa kwako kwe darunavir kukatanga kudzikira, tora zvimwe kubva kuna chiremba wako kana wemishonga.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora darunavir,

• udza chiremba wako uye wemishonga kana uri weergoria kune darunavir, ritonavir, sulfa mishonga, chero mimwe mishonga, kana chero chinosanganisa mumapiritsi eDarunavir kana kumiswa. Kumbira wemishonga wako kuti uwane runyorwa rwezvigadzirwa kana kuti kana usina chokwadi kana mushonga wauri weergoriki uri mushonga wesulfa.
• udza chiremba wako kana iwe uri kutora chero einotevera mishonga: alfuzosin (Uroxatral); cisapride (Propulsid) (haisipo muU.S.); dronedarone (Multaq); elbasvir / grazoprevir (Zepatier); ergot-mhando mishonga senge dihydroergotamine (DHE 45, Migranal), ergotamine (Ergomar, muCafergot, muMigergot), uye methylergonovine (Methergine); lomitapide (Juxtapid); lovastatin (Mevacor, muna Advicor); lurasidone (Latuda), midazolam (yakapihwa nemuromo); pimozide (Orap); ranolazine (Ranexa); rifampin (Rifadin, Rimactane, muRifamate, muRifater); sildenafil (chete Revatio brand inoshandiswa pachirwere chemapapu); simvastatin (Zocor, muVytorin); Wort St. kana triazolam (Halcion). Chiremba wako angangokuudza kuti usatora darunavir. Zvakare, kana iwe uine chirwere cheitsvo kana chiropa uye uri kutora colchicine (Colcrys, Mitigare, muCol-Probenecid), chiremba wako anogona kukuudza kuti usatore darunavir.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: anticoagulants ('blood thinner') senge apixaban (Eliquis), rivaroxaban powder (Xarelto), uye warfarin (Coumadin, Jantoven); antifungals senge itraconazole (Onmel, Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), uye voriconazole (Vfend); artemether / lumefantrine (Coartem); beta blockers senge carvedilol (Coreg), metoprolol (Lopressor, Toprol XL, muDutoprol, muLopressor HCT), uye timolol (Betimol, Istalol, muCombigan, muCosopt, vamwe); betamethasone; boceprevir (haichawanikwi muU.S.; Victrelis); bosentan (Tracleer); budesonide (Entocort, Pulmicort, Uceris, vamwe); buprenorphine (Belbuca, Buprenex, Butrans, muSuboxone, vamwe); buprenorphine / naloxone (Bunavail, Suboxone, Zubsolv); buspirone; calcium-chiteshi blockers senge amlodipine (Norvasc, muCaduet), diltiazem (Cardizem CD, Cartia, XT, Diltzac, vamwe), felodipine (Plendil), nicardipine (Cardene), nifedipine (Adalat CC, Afebitab CR, Procardia), uye verapamil (Calan, Covera, Verelan, muTarka); mamwe chemotherapy mishonga yakadai sedasatinib (Sprycel), nilotinib (Tasigna), vinblastine, uye vincristine (Marqibo Kit); cholesterol-kudzikisa mishonga (statins) senge atorvastatin (Lipitor, muCaduet), pravastatin (Pravachol), uye rosuvastatin (Crestor); ciclesonide (Alvesco); clarithromycin (Biaxin, muPrevpac); mimwe mishonga yekushungurudzika senge amitriptyline, desipramine (Norpramin), imipramine, nortriptyline, paroxetine (Brisdelle, Paxil, Pexeva), sertraline (Zoloft), uye trazodone; dexamethasone; diazepam (Diastat, Valium); estazolam; fentanyl (Abstral, Duragesic, Subsys); fluticasone (Flonase, Flovent, muAdvair); mimwe mishonga yehutachiona hwehepatitis C (HCV) senge glecaprevir / pibrentasvir (Mavyret) uye simeprevir (haichawanikwi muU.S.; Olysio); mimwe mishonga yeHIV inosanganisira indinavir (Crixivan), lopinavir / ritonavir (Kaletra), maraviroc (Selzentry), uye saquinavir (Invirase); mahormone (estrogen) ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, zvinomisikidza, kana majekiseni); mishonga yekusagadzikana kwemoyo kusanganisa amiodarone (Nexterone, Pacerone), bepridil (haichawanikwi muUS), digoxin (Lanoxin), disopyramide (Norpace), flecainide, lidocaine (Xylocaine), mexiletine, propafenone (Rythmol), uye quinidine (muNuedexta ); mimwe mishonga yekubatwa kwakadai se carbamazepine (Carbatrol, Equetro, Tegretol, vamwe), clonazepam (Klonopin), phenobarbital, uye phenytoin (Dilantin, Phenytek); mimwe mishonga inodzvinyirira immune system se cyclosporine (Gengraf, Neoral, Sandimmune), everolimus (Afinitor, Zortress), sirolimus (Rapamune), uye tacrolimus (Astagraf XL, Prograf); methadone (Dolophine, Methadose); methylprednisolone; mometasone (Asmanex); omeprazole (Prilosec); oxycodone (Xtampza); zvimwe phosphodiesterase inhibitors (PDE-5 inhibitors) inoshandiswa kusagadzikana kwe erectile sevanavana (Stendra), sildenafil (Viagra), tadalafil (Cialis), uye vardenafil (Levitra, Staxyn); perphenazine; prednisone (Rayos); quetiapine (Seroquel); rifabutin (Mycobutin); rifapentine (Priftin); risperidone (Risperdal); salmeterol (Serevent, muAdvair); tadalafil (Adcirca); thioridazine; ticagrelor (Brilinta); tramadol (Conzip); triamcinolone (Nasacort); uye zolpidem (Ambien, Edluar, Intermezzo). Mimwe mishonga yakawanda inogona zvakare kusangana ne darunavir, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• kana iwe uri kutora didanosine (Videx), tora iyo 1 awa pamberi kana maviri maawa mushure mekutora darunavir.
• udza chiremba wako kana iwe kana wakambove nechirwere cheshuga kana shuga yakakwira muropa; hemophilia (kubuda ropa kusagadzikana uko ropa risingaputike zvakanaka); hepatitis (kuzvimba kwechiropa kunokonzerwa nehutachiona), cirrhosis (chirwere chinokonzeresa kuvenga kwechironda tishu), kana chimwewo chirwere chechiropa; kana hutachiona husingaendi kana hunouya huchienda se cytomegalovirus (CMV; hutachiona hutachiona hunogona kukonzeresa zviratidzo muvarwere vane immune system isina kusimba), mycobacterium avium tata chirwere (MAC; hutachiona hutachiona hunogona kukonzera zvakakomba zviratidzo mukati vanhu vane AIDS), mabayo, kana tibhii (TB; rudzi rwehutachiona hwemapapu).
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri uchitora darunavir, danaidza chiremba wako. Usayamwise mwana kana uine hutachiwana hweHIV kana kuti uri kutora darunavir.
• iwe unofanirwa kuziva kuti darunavir inogona kudzikisira kushanda kwemahomoni ekudzivirira kubata pamuviri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, majekiseni, kana mapiritsi). Taura nachiremba wako nezve isiri-mahormone yekudzivirira kuberekwa senzira yekudzivirira (mudziyo unodzivirira urume kuti usapinda muchibereko sekondomu kana diaphragm) kudzivirira kubata pamuviri paunenge uchinwa mushonga uyu. Kumbira chiremba wako kuti akubatsire kusarudza nzira yekudzivirira kuberekwa iyo ichakushandira iwe.
• iwe unofanirwa kuziva kuti muviri wako mafuta unogona kuwedzera kana kuenda kunzvimbo dzakasiyana dzemuviri wako senge mazamu ako, kumusoro kumashure, mutsipa, chifuva, uye mudumbu nzvimbo. Kurasikirwa kwemafuta kubva kumakumbo, maoko, uye kumeso zvinogona kuitika.
• iwe unofanirwa kuziva kuti iwe unogona kusangana ne hyperglycemia (inowedzera mushuga yeropa rako) paunenge uchitora mushonga uyu, kunyangwe kana usati uine chirwere cheshuga. Udza chiremba wako nekukasira kana uine chimwe chezviratidzo zvinotevera paunenge uchitora darunavir: nyota yakanyanya, kuita weti kakawanda, nzara yakanyanyisa, kusaona zvakanaka, kana kushaya simba. Zvakakosha kusheedza chiremba wako nekukurumidza kana uchinge uine chero cheizvi zviratidzo, nekuti shuga yepamusoro yeropa isingarapwe inogona kukonzera chirwere chakakomba chinonzi ketoacidosis. Ketoacidosis inogona kutyisidzira hupenyu kana ikasarapwa padanho rekutanga. Zviratidzo zve ketoacidosis zvinosanganisira: kuoma muromo, kuda kurutsa uye kurutsa, kufema kufema, mweya unonhuwira muchero, uye kudzikira kwekuziva.
• Unofanirwa kuziva kuti paunenge uchinwa mishonga yekurapa hutachiona hweHIV, immune system yako inogona kusimba uye yotanga kurwisa zvimwe zvirwere zvaive mumuviri wako kare. Izvi zvinogona kukonzera kuti iwe uwedzere zviratidzo zveawo hutachiona. Kana uine zviratidzo zvitsva kana zvichikura panguva ipi neipi panguva yekurapwa kwako nedharunavir, ita chokwadi chekuudza chiremba wako.

Taura nachiremba wako nezve kudya mazambiringa uye kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.

Kana iwe uri kutora darunavir kamwe pazuva uye ukarasikirwa nedhidhi nemaawa asingasviki gumi nemaviri, tora iyo yakarasika dosi nekukurumidza paunenge uchirangarira uye wotora inotevera dosi panguva yakatarwa. Nekudaro, kana iwe ukarasikirwa nedhiza nemaawa anopfuura gumi nemaviri, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana iwe uri kutora darunavir kaviri pazuva uye ukarasikirwa nedhidhi nemaawa asingasviki matanhatu, tora iyo yakarasika dosi nekukurumidza kana uchinge uchinge uchinge uchinge uchinge uchinge watora iyo inotevera dosi panguva yakatarwa. Nekudaro, kana iwe ukarasikirwa nedhiza nemaawa anodarika matanhatu, ruka iro rakarasika uye ramba uchiita yako yenguva dzose dosing chirongwa. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Darunavir inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• manyoka
• kurutsa
• kurwadziwa nemudumbu
• kuvimbiswa

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona chimwe chezviratidzo izvi, rega kutora darunavir uye udane chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira

• mapundu
• kubvarura kana kubvarura ganda
• maronda emuromo
• dzvuku, kuzvimba, kunhuwa, kana kuchema maziso
• mhasuru kana majoini akabatana
• kupindwa nechando
• kuzvimba, unyoro, kutsvuka, kana zvimwe zviratidzo zvehutachiona
• kusvotwa
• kuneta zvakanyanya
• kurasikirwa nenzara
• kurwadziwa kumusoro kwepamusoro chikamu chedumbu
• yero yeganda kana maziso
• dzakachenuruka kana dzakasviba zvituru

Darunavir inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo pamhepo pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mimwe bvunzo kuti uve nechokwadi chekuti zvakachengeteka kuti iwe utore darunavir uye kutarisa mhinduro yemuviri wako kune darunavir.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Prezista^®
• Prezcobix^® (iine Darunavir, Cobicistat)

• TMC-114