Munyori: Virginia Floyd
Zuva Rekusika: 6 Nyamavhuvhu 2021
Gadziridza Zuva: 13 Mbudzi 2024
Anonim
HCC: Use of Lenvatinib and Sorafenib
Vhidhiyo: HCC: Use of Lenvatinib and Sorafenib

Zvemukati

Sorafenib inoshandiswa kurapa yakakwira renal cell carcinoma (RCC; mhando yekenza inotanga muitsvo). Sorafenib inoshandiswawo kurapa hepatocellular carcinoma (rudzi rwegomarara rechiropa) iyo isingakwanise kurapwa nekuvhiyiwa uye imwe mhando yekenza yeutachiona yakapararira kune dzimwe nhengo dzemuviri uye isingakwanise kurapwa neayodini ine radioactive. Sorafenib ari mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kupararira kwekenza masero.

Sorafenib inouya sehwendefa kutora nemuromo. Inowanzotorwa kaviri pazuva. Sorafenib inotorwa isina chikafu, 1 awa pamberi kana maviri maawa mushure mekudya. Tora sorafenib kwakatenderedza nguva dzakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora sorafenib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Medza mapiritsi akazara nemvura. Usaparadzanise, kutsenga, kana kuvapwanya.

Chiremba wako anogona kudzikisira muyero wako we sorafenib panguva yekurapwa kwako, kana anogona kukuudza kuti umbomira kwenguva pfupi kana zvachose kutora sorafenib kwenguva yakati kana iwe ukava nemhedzisiro. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako ne sorafenib.

Ramba uchitora sorafenib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora sorafenib usina kutaura nachiremba wako.

Sorafenib haiwanike mumafamasi. Iwe unogona chete kuwana sorafenib kuburikidza netsamba kubva kune yakasarudzika pharmacy. Kumbira chiremba wako kana iwe uine chero mibvunzo nezve kugashira kwako mushonga.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora sorafenib,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune sorafenib, chero mimwe mishonga, kana chero chinhu chinowanikwa mumatafura e sorafenib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana uine kenza yemapapu uye urikurapwa ne carboplatin (Paraplatin) uye paclitaxel (Abraxane, Onxol, Taxol) kana gemcitabine (Gemzar) uye cisplatin (Platinol). Chiremba wako angangokuudza kuti usatora sorafenib kana uine kenza yemapapu uye uri kugamuchira iyi mishonga.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mimwe mishonga ye arrhythmias senge amiodarone (Nexterone, Pacerone), dofetilide (Tikosyn), dronedarone (Multaq), procainamide, quinidine (muNuedexta), uye sotalol (Betapace, Sorine, Sotylize); anticoagulants (ropa rakatetepa) senge warfarin (Coumadin, Jantoven); carbamazepine (Equetro, Tegretol, Teril); dexamethasone; ibutilide (Corvert); irinotecan (Camptosar); neomycin; phenobarbital; phenytoin (Dilantin, Phenytek); rifabutin (Mycobutin); kana rifampin (Rifadin, Rimactane). Mimwe mishonga yakawanda inogona zvakare kusangana ne sorafenib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
  • udza chiremba wako kana iwe wakambove neakakwira BP, matambudziko ekubuda ropa, kurwadziwa pachipfuva, matambudziko emoyo, QT kuwedzerwa (irregular moyo rhythm iyo inogona kutungamira mukufenda, kurasikirwa kwekuziva, kubatwa, kana kufa kamwe kamwe) potasium, calcium, kana magnesium muropa rako, kurova kwemoyo zvisina kujairika, kutadza kwemoyo, matambudziko eitsvo kunze kwekenza yetsvo, kana matambudziko echiropa kunze kwegomarara rechiropa.
  • udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe uchafanirwa kutora bvunzo yepamuviri usati watanga kurapwa. Kana iwe uri mukadzi anokwanisa kuve nepamuviri, iwe unofanirwa kushandisa anoshanda ekudzivirira kubereka panguva yekurapa kwako uye kwemwedzi mitanhatu mushure meiyo dosi yekupedzisira. Kana iwe uri murume aine mukadzi mukadzi waunogona kuve nepamuviri, iwe unofanirwa kushandisa anoshanda ekuberekesa kudzora panguva yekurapa kwako uye kwemwedzi mitatu mushure meyako yekupedzisira dosi. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri uchitora sorafenib, dana chiremba wako nekukurumidza. Sorafenib inogona kukuvadza fetus.
  • udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Iwe haufanire kuyamwa uchi tora sorafenib uye kwemavhiki maviri mushure mekupedzisira kwedosi.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora sorafenib.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.


Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Sorafenib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kuneta
  • kushaya simba
  • kutsvuka kweganda
  • kurasikirwa nevhudzi
  • kuvava
  • kuoma kana kubvisa ganda
  • kurasikirwa nenzara
  • kuvimbiswa
  • manyoka
  • muromo wakaoma
  • kuonda
  • kurwadza kwemajoini
  • chiveve, kurwadziwa kana kugwinha maoko kana tsoka
  • musoro

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

  • kupwanya kusingawanzo kana kubuda ropa
  • nhema uye / kana zvigaro zvekugara
  • ropa dzvuku muzvituru
  • kurutsa kweropa
  • kurutsa zvinhu zvinoita kunge kofi nzvimbo
  • kupindwa nechando
  • kurwadziwa kwakanyanya mudumbu
  • kusvotwa
  • kurutsa
  • kurwadziwa pachipfuva
  • mweya wekufema
  • dzungu kana kupera simba
  • vangadikitira zvakanyanya
  • nekukurumidza, kurovera, kana kurova kwemoyo zvisina kujairika
  • pakarepo musoro wakakomba
  • kuvhiringidzika
  • shanduko pane zvakaratidzwa
  • pfari
  • mapundu
  • kutsvuka, kurwadziwa, kuzvimba kana mablisters muzvanza zvemaoko kana pasi petsoka
  • ganda rinotumbuka uye kubvarura
  • mikoko
  • kuvava
  • kutsvuka kweganda
  • maronda emuromo
  • weti yakasviba
  • yero yeganda kana maziso
  • kurwadziwa kumusoro kwepamusoro chikamu chedumbu

Sorafenib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.


Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • manyoka
  • mapundu kana mamwe matambudziko eganda

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti atarise mhinduro yemuviri wako kune sorafenib Chiremba wako anozoongorora zvekare kuwedzerwa kweropa rako vhiki rega rega mukati memavhiki matanhatu ekutanga ekurapwa kwako uyezve nguva nenguva sezvazvinodiwa.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Nexavar®
Yekupedzisira Yakagadziridzwa - 02/15/2019

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