Sunitinib

Zvemukati

• Usati watora sunitinib,
• Sunitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa mune ZVINOKOSHA YENYENZO kana ZVINOKOSHA ZVINONYANYA, daidza chiremba wako nekukasira:

Sunitinib inogona kukonzera zvakakomba kana kutyisidzira hupenyu kuchiropa. Udza chiremba wako kana iwe wakambove kana wakambove nechirwere chechiropa kana matambudziko nechiropa chako. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, fonera chiremba wako nekukasira: kuchenesa, maziso eyero uye ganda, weti yakasviba, kana kurwadziwa kana kusagadzikana munzvimbo yekurudyi yepamusoro mudumbu. Chiremba wako angangofanira kudzikisa yako sunitinib kana zvachose kana kumbomira kurapwa.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira kumwe kuongorora kweropa usati uye panguva yekurapwa kwako kuve nechokwadi kuti zvakachengeteka kuti iwe utore sunitinib uye kutarisa mhinduro yemuviri wako kumushonga.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa ne sunitinib uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekutora sunitinib.

Sunitinib inoshandiswa kurapa utumbo stromal tumors (GIST; rudzi rwebundu rinokura mudumbu, ura (ura), kana esophagus (chubhu inobatanidza huro nedumbu) mune vanhu vane mamota asina kurapwa zvakabudirira ne imatinib ( Gleevec) kana vanhu vasingakwanise kutora imatinib.Sunitinib inoshandiswawo kurapa yakakwira renal cell carcinoma (RCC, rudzi rwekenza inotangira mumasero eitsvo) Sunitinib inoshandiswa zvakare kubatsira kudzivirira kudzoka kweRCC muvanhu vane RCC isina kupararira uye yakabviswa itsvo.Sunitinib inoshandiswawo kurapa tumachiropa (pancreatic) Sunitinib iri mukirasi yemishonga inonzi kinase inhibitors.Iyo inoshanda nekuvhara maitiro epuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande.Izvi zvinobatsira kumisa kana kudzora kupararira kwemasero ekenza uye zvinogona kubatsira shrink tumors.

Sunitinib inouya sekapuleti kutora nemuromo kana kana pasina chikafu. Nekurapa kwepamuviri stromal tumors (GIST), kana yekurapa renal cell carcinoma (RCC), sunitinib inowanzo kutorwa kamwe chete pazuva kwevhiki ina (mazuva makumi maviri nemasere) ichiteverwa nekuzorora kwevhiki mbiri usati watanga inotevera dosing kutenderera uye inodzokororwa vhiki dzese dze6 kwenguva yakareba sekurudzirwa nachiremba wako. Nekudzivirira kweRCC, sunitinib inowanzo kutorwa kamwe chete pazuva kwevhiki ina (mazuva makumi maviri nemasere) ichiteverwa nekuzorora kwemavhiki maviri usati watanga inotevera dosing kutenderera uye kudzokorora mavhiki matanhatu ese e9 kutenderera. Nekurapa kwepancreatic neuroendocrine tumors (pNET), sunitinib inowanzo kutorwa kamwe chete zuva nezuva. Tora sunitinib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora sunitinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsules akazara; usatsemure, kutsenga, kana kuvapwanya. Usavhure macapsule.

Iwe ungangoda kutora rimwe kana akawanda makapisi panguva imwe zvichienderana nedosi rako re sunitinib.

Chiremba wako anogona kuwedzera zvishoma nezvishoma kana kudzikisa yako sunitinib panguva yekurapa kwako. Izvi zvinoenderana nekuti mushonga unoshanda sei kwauri uye nemhedzisiro iwe yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora sunitinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora sunitinib usina kutaura nachiremba wako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora sunitinib,

• udza chiremba wako uye wemishonga kana uri weergergic kune sunitinib, chero zvigadzirwa zve sunitinib capsules, kana chero mimwe mishonga. Bvunza wako wemishonga kana tarisa yemugadziri yemurwere pepa reruzivo (Mishonga Gwara) kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe maantibhakitiriya akadai clarithromycin (Biaxin, muPrevpac), rifampin (Rifadin, Rimactane, muRifamate, muRifater), rifabutin (Mycobutin), rifapentine (Priftin), uye telithromycin (Ketek); mamwe maantifungal akadai itraconazole (Onmel, Sporanox), ketoconazole, uye voriconazole (Vfend); dexamethasone; mishonga yechirwere cheshuga; mimwe mishonga yehutachiona hwehutachiona hweHIV (HIV) kana yakawana immunodeficiency syndrome (AIDS) inosanganisira atazanavir (Reyataz, muEvotaz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, muCaletra), uye saquinavir (Invirase); nefazodone; mimwe mishonga yekubatwa senge carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), phenobarbital, uye phenytoin (Dilantin, Phenytek). Uyezve udza chiremba wako kana uri kutora kana kutora alendronate (Binosto, Fosamax), etidronate, ibandronate (Boniva), pamidronate, risedronate (Actonel, Atelvia), kana zoledronic acid jekiseni (Reclast, Zometa), Mimwe mishonga inogona zvakare kusangana sunitinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isingaonekwe pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako uye wemishonga kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort. Usatora St. John's wort uchitora sunitinib.
• udza chiremba wako kana iwe kana wakambove nechinetso chekubuda ropa; kuvhara ropa mumapapu; kuwedzera kwenguva yenguva yeQT (irregular moyo rhythm iyo inogona kutungamira mukufenda, kurasikirwa kwekuziva, kubatwa, kana kufa kamwe kamwe); inononoka, inokurumidza, kana isina kujairika kurova kwemoyo; chirwere chemwoyo; kutadza kwemoyo; kukwirira kweropa; pfari; shuga shoma yeropa kana chirwere cheshuga; yakaderera masosi e potassium kana magnesium muropa rako; matambudziko nemuromo wako, mazino kana matadza; kana itsvo, thyroid, kana chirwere chemwoyo.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kana iwe uchironga kubereka mwana. Iwe kana mumwe wako haufanire kubata pamuviri iwe uchitora sunitinib. Kana iwe uri munhukadzi, iwe uchafanirwa kuve nemimba yekubata usati watanga kurapwa, uye iwe unofanirwa kushandisa kuberekwa kudzivirira kudzivirira kubata pamuviri panguva yezuva rako sunitinib kurapwa uye kwemavhiki mana mushure meyako yekupedzisira dosi. Kana iwe uri murume, iwe nemumwe wako munofanira kushandisa kuberekwa kudzivirira kubata pamuviri panguva yekurapa kwako ne sunitinib uye kwemavhiki manomwe mushure meyako yekupedzisira dosi. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa panguva yekurapa kwako. Sunitinib inogona kudzora kubereka muvarume nevakadzi. Nekudaro, iwe haufanire kufunga kuti iwe kana mumwe wako haugone kuve nepamuviri. Kana iwe kana mumwe wako mukava nepamuviri muchitora sunitinib, danai chiremba wako. Sunitinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa. Iwe haufanire kuyamwisa panguva yekurapa kwako ne sunitinib uye kwemavhiki mana mushure mekupedzisira kwako.
• kana uri kuvhiyiwa udza chiremba kana chiremba wemazino kuti urikutora sunitinib. Chiremba wako angangokuudza kuti rega kutora sunitinib kwemavhiki matatu usati wavhiyiwa zvakarongwa nekuti zvinogona kukanganisa kupora kwemaronda. Chiremba wako anokuudza iwe nguva yekutanga kutora sunitinib zvakare mushure mekuvhiyiwa kwako.
• iwe unofanirwa kuziva kuti sunitinib inogona kukonzera ganda rako kushanduka yero uye vhudzi rako kujekesa uye kurasikirwa nemuvara. Izvi zvinogona kunge zvichikonzerwa neyero yeyadhi yemushonga uye haina kukuvadza kana kurwadza.
• iwe unofanirwa kuziva kuti sunitinib inogona kukonzera kukwira kweropa. Ropa rako rinofanira kuongororwa nguva dzose paunenge uchitora sunitinib.
• iwe unofanirwa kuziva kuti sunitinib inogona kukonzera osteonecrosis yeshaya (ONJ, yakakomba mamiriro ejaya pfupa), kunyanya kana iwe uchivhiyiwa mazino kana kurapwa paunenge uchitora mushonga. Chiremba wemazino anofanira kuongorora mazino ako uye aite chero marapirwo anodikanwa, kusanganisira kuchenesa kana kugadzirisa mazino asina kukodzera, usati watanga kutora sunitinib. Ive neshuwa yekugeza mazino nekuchenesa muromo wako zvakanaka paunenge uchitora sunitinib. Udza chiremba wako kana chiremba wemazino kana iwe wakamborwadziwa mumuromo, mazino kana shaya; maronda emuromo kana kuzvimba; chiveve kana kunzwa kuremerwa shaya; kana chero mazino akasununguka. Taura nachiremba wako usati wawana chero kurapwa kwemazino iwe paunenge uchinwa mushonga uyu.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.

Kana iwe ukarasikirwa neiyo sunitinib nemaasingasviki maawa gumi nemaviri, tora iyo yakarasika dhizai nekukurumidza kana uchinge uchinge uchinge uchinge uchinge uchinge watora iyo inotevera dosi panguva yakarongwa. Nekudaro, kana iwe ukarasikirwa nedhiza nemaawa anopfuura gumi nemaviri, ruka iro rakarasika dhizaini uye enderera yako yenguva dzose dosing purogiramu Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Sunitinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kushaya simba
• kusvotwa
• kurutsa
• manyoka
• kuvimbiswa
• chirungurira
• gasi
• Mamota
• kurwadziwa, kutsamwa, kana kupisa kutsamwa kwemiromo, rurimi, muromo kana huro
• muromo wakaoma
• chinja munzira iyo zvinhu zvinonaka
• kurasikirwa nenzara
• uremu hunochinja
• kurasikirwa nevhudzi
• nzara, mutswe, nzara kana bvudzi
• kutaura kunonoka
• ganda rakachenuruka kana kuoma
• kuzunza
• zvinorema, zvisina kujairika, kana kurasikirwa nemwedzi
• kuora mwoyo
• kunetseka kurara kana kuramba wakarara
• kuoma, ukobvu, kutsemuka, kana kutsemuka kweganda pazvanza zvemaoko uye pasi petsoka
• mhasuru, kubatana, musana, kana kurwadziwa kwemakumbo
• kazhinji kubuda mhino
• kubuda ropa kubva mumatadza ako
• kujairika kusagadzikana mukutonhora kutonhora

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa mune ZVINOKOSHA YENYENZO kana ZVINOKOSHA ZVINONYANYA, daidza chiremba wako nekukasira:

• kupwanya kusingawanzo kana kubuda ropa
• reropa kana dema uye zvigaro zvekugara
• ropa mumurini
• rutsa iro rakatsvuka tsvuku kana rinotaridzika senge nzvimbo yekofi
• kukosora ropa
• kurwadziwa mudumbu, kuzvimba, kana unyoro
• musoro
• kupindwa nechando
• kuzvimba, unyoro, kudziya, kana kutsvuka kwegumbo
• kuzvimba kwetsoka kana makumbo
• inokurumidza, isina kujairika, kana kurova kurova kwemoyo
• dzungu kana kupera simba
• kuderera kwekusvinura kana kuisa pfungwa
• kuvhiringidzika
• kuora mwoyo
• huta
• pfari
• maonero anochinja
• kurwadziwa pachipfuva kana kumanikidza
• kuneta zvakanyanya
• mweya wekufema
• kurwadziwa nekufema kwakadzika
• zvisina tsananguro kuwedzera uremu
• kuderera kwekuita weti
• weti ine makore
• kuzvimba kwemaziso, kumeso, miromo, rurimi kana huro
• mapundu
• mikoko
• kuputika kana kubvisa ganda kana mukati memuromo
• kunetseka kumedza kana kufema
• hoarseness

Sunitinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anogona kuraira mimwe bvunzo senge electrocardiograms (EKG, bvunzo inorekodha mashandiro emagetsi emoyo), echocardiograms (bvunzo inoshandisa mafungu eruzha kuyera kugona kwemoyo wako kupomba ropa), uye weti miedzo usati uye panguva yekurapa kwako sunitinib kuve nechokwadi kuti zvakachengeteka kuti iwe utore sunitinib, uye kutarisa mhinduro yemuviri wako kumushonga.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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