Munyori: William Ramirez
Zuva Rekusika: 19 Gunyana 2021
Gadziridza Zuva: 22 Ndira 2025
Anonim
Dasatinib in the Second-Line Setting
Vhidhiyo: Dasatinib in the Second-Line Setting

Zvemukati

Dasatinib inoshandiswa kurapa imwe mhando yechirwere chisingaperi che myeloid leukemia (CML; rudzi rwekenza yemasero machena eropa) sekutanga kurapwa uye mune vanhu vasingachagone kubatsirwa nemimwe mishonga yeleukemia inosanganisira imatinib (Gleevec) kana mune avo haikwanise kutora mishonga iyi nekuda kwemhedzisiro. Dasatinib inoshandiswawo kurapa rumwe rudzi rweusingaperi CML muvana. Dasatinib inoshandiswawo kurapa imwe mhando yeacute lymphoblastic leukemia (ZVESE; rudzi rwekenza yemasero machena eropa) mune vanhu vasingachagone kubatsirwa nemamwe mishonga yeleukemia kana vasingakwanise kutora mishonga iyi nekuda kwemhedzisiro. Dasatinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chepuroteni isina kujairika iyo inoratidza masero ekenza kuti iwande. Izvi zvinobatsira kumisa kupararira kwekenza masero.

Dasatinib inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva, mangwanani kana manheru, pamwe kana pasina chikafu. Tora dasatinib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora dasatinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya. Pfeka magurovhosi kana nitrile magirafu paunenge uchibata mahwendefa akapwanywa netsaona kana kuputswa kudzivirira kusangana nemushonga.

Chiremba wako anogona kugadzirisa dhizaini yako kana kumisa zvachose kurapwa kwako kwedasatinib zvichienderana nemhinduro yako pakurapwa uye chero mhedzisiro iwe yaunosangana nayo. Taura nachiremba wako nezve manzwiro auri kuita panguva yekurapwa kwako. Ramba uchitora dasatinib kunyangwe iwe uchinzwa zvakanaka. Usarega kutora dasatinib usina kutaura nachiremba wako.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora dasatinib,

  • udza chiremba wako uye wemishonga kana iwe uri weergoria kune dasatinib, chero mimwe mishonga, kana chero chinhu chinosanganiswa mumapiritsi eDasatinib. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: anticoagulants ('' vatete veropa '') senge warfarin (Coumadin, Jantoven); anthracycline mishonga yegomarara senge daunorubicin (Cerubidine), doxorubicin (Doxil), uye epirubicin (Ellence); mamwe maantifungal akadai ketoconazole (Nizoral), itraconazole (Onmel, Sporanox), uye voriconazole (Vfend); clarithromycin (Biaxin, muPrevPac); dexamethasone; mimwe mishonga inoshandiswa kurapa hutachiona hwehutachiwana hwevanhu (HIV) senge atazanavir (Reyataz), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), uye saquinavir (Invirase); mimwe mishonga yekushaya moyo zvisina kujairika senge amiodarone (Nexterone, Pacerone), disopyramide (Norpace), dofetilide (Tikosyn), flecainide (Tambocor), mexiletine (Mexitil), procainamide, propafenone (Rythmol), quinidine (muNuedextol), Betapace, Betapace AF, Sorine), mishonga yekudzikisa dumbu acid secimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), ranitidine (Zantac), esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), uye rabeprazole (AcipHex); nefazodone; rifampin (Rimactane, Rifadin, muRifater, muRifamate); uye telithromycin (Ketek); Mimwe mishonga yakawanda inogona zvakare kusangana ne dasatinib, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • kana uri kutora antacids, senge aluminium hydroxide / magnesium hydroxide (Maalox), calcium carbonate (Tums), kana calcium carbonate uye magnesium (Rolaids), tora iwo maawa maviri pamberi kana maviri maawa mushure mekutora dasatinib.
  • udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
  • udza chiremba wako kana iwe wakambove kana kusagadzikana kwe lactose (kutadza kugaya zvigadzirwa zvemukaka), mashoma potasium kana magnesium muropa rako, refu QT syndrome (mamiriro emoyo anogona kukonzeresa dzungu, kufenda, kana kusagadzikana kwemwoyo), matambudziko ne immune system yako, kana chiropa, mapapu, kana chirwere chemwoyo.
  • udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Iwe haufanire kuve nepamuviri iwe paunenge uchitora dasatinib uye kwemazuva makumi matatu mushure mekupedzisira kwezita rako. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinokushandira. Kana iwe ukava nepamuviri uchitora dasatinib, danaidza chiremba wako. Vakadzi vane nhumbu havafanirwe kubata akapwanyika kana akaputswa mahwendefa edasatinib. Dasatinib inogona kukuvadza fetus.
  • usamwisa mwana paunenge uchitora dasatinib uye kwemavhiki maviri mushure mekupedzisira kwedosi.
  • iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume nevakadzi. Taura nachiremba wako nezve njodzi dzekutora dasatinib.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora dasatinib.

Usadye grapefruit kana kunwa muto wemazambiringa uchinwa mushonga uyu.


Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Dasatinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kurwadziwa kwemhasuru
  • kushaya simba
  • kurwadza kwemajoini
  • kurwadziwa, kutsva kana kurira mumaoko kana mutsoka
  • mapundu
  • kutsvuka kweganda
  • kubvisa ganda
  • kuzvimba, kutsvuka, uye kurwadziwa mukati memuromo
  • maronda emuromo
  • manyoka
  • kusvotwa
  • kurutsa
  • kuvimbiswa
  • kurwadziwa nemudumbu kana kuzvimba
  • kurasikirwa nenzara
  • kuonda

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • fivha, huro, chironda, uye / kana zvimwe zviratidzo zvehutachiona
  • kuzvimba kwemaziso, maoko, maoko, tsoka, makumbo, kana makumbo ezasi
  • kamwe kamwe kuwedzera uremu
  • kunetseka kufema, kunyanya kana wakarara pasi
  • kukosora pingi kana ropa rinobuda ropa
  • chikosoro chakaoma
  • kurwadziwa pachipfuva kunowedzera kana uchikosora, kuhotsira, kana kufema zvakadzama
  • chipfuva kumanikidza
  • dzungu
  • kufenda
  • inokurumidza, isina kujairika, kana kurova kurova kwemoyo
  • musoro
  • kuneta
  • kuvhiringidzika
  • kuwedzera kwenguva pfupi kwezamu (muvana)
  • kupwanya kusingawanzo kana kubuda ropa
  • nhema uye yekumhara zvituru
  • ropa dzvuku muzvituru
  • kurutsa kweropa
  • kurutsa zvinhu zvinoita kunge kofi nzvimbo
  • kutaura kunonoka kana kuoma
  • kushaya simba kana kushama ruoko kana gumbo

Dasatinib inogona kukonzera kunonoka kukura kana kurwadziwa kwepfupa muvana. Chiremba wemwana wako anoongorora kukura kwemwana wako zvakanaka paanenge achitora dasatinib. Taura nachiremba wako nezve njodzi dzekupa uyu mushonga kumwana wako.


Dasatinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo runowanikwawo pamhepo pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • kupwanya kusingawanzo kana kubuda ropa
  • fivha, huro, chironda, uye / kana zvimwe zviratidzo zvehutachiona
  • mweya wekufema
  • kukurumidza kurova kwemoyo
  • musoro
  • ganda rakachenuruka
  • kuvhiringidzika
  • kuneta

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira kumwe kuongorora kwelebhu usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune dasatinib

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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Yekupedzisira Yakagadziridzwa - 01/15/2018

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