Lenalidomide

Zvemukati

• Usati watora lenalidomide,
• Lenalidomide inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:
• Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

Ngozi yekuremara kwehupenyu hunotyisidzira hupenyu hwekuzvarwa hunokonzerwa nelenalidomide:

Kune vese varwere:

Lenalidomide haifanire kutorwa nevarwere vane nhumbu kana vanogona kuve nepamuviri. Pane njodzi huru yekuti lenalidomide inokonzeresa kuremara kwekuzvara (matambudziko aripo pakuzvarwa) kana kufa kwemwana asati aberekwa.

Chirongwa chinonzi REVLIMID REMS^TM yakagadzirirwa kuti ive nechokwadi chekuti vakadzi vane nhumbu havatore lenalidomide uye kuti vakadzi havaite nhumbu pavanotora lenalidomide. Vese varwere, kusanganisira vakadzi vasingakwanise kuve nepamuviri nevarume, vanogona kuwana lenalidomide chete kana vakanyoreswa neREVLIMID REMS, vane tsamba kubva kunechiremba uyo akanyoreswa neREVLIMID REMS, uye zadza iwo mushonga kukiriniki iyo yakanyoreswa neREVLIMID REMS .

Iwe unozogashira ruzivo nezve njodzi dzekutora lenalidomide uye unofanirwa kusaina pepa rekubvumirwa rine ruzivo unotaura kuti unonzwisisa ruzivo urwu usati wagamuchira mushonga. Kana iwe uri mudiki pamakore gumi nemasere ekuberekwa, mubereki kana muchengeti anofanirwa kusaina pepa rekubvuma uye obvuma kuona kuti wasangana nezvinodiwa izvi. Iwe unozofanirwa kuona chiremba wako panguva yekurapwa kwako kuti utaure nezve mamiriro ako uye mhedzisiro yauri kusangana nayo kana kuti kuve nemimba yekuyedza sezvakakurudzirwa nechirongwa. Ungangoda kupedzisa ongororo yakavanzika pakutanga kwekurapwa kwako uye pane dzimwe nguva panguva yekurapwa kwako kuti uve nechokwadi chekuti wagamuchira uye unzwisise ruzivo urwu uye kuti iwe unogona kutevedzera rairo dzekudzivirira njodzi dzakakomba kuvacheche vasati vazvarwa.

Udza chiremba wako kana iwe usinganzwisise zvese zvawakaudzwa nezve lenalidomide uye chirongwa cheREVLIMID REMS uye mashandisiro ekushandisa nzira dzekudzivirira kuberekwa dzakakurukurwa nachiremba wako, kana kana iwe usingafunge kuti uchakwanisa kuchengeta nguva.

Usape ropa iwe paunenge uchitora lenalidomide, panguva ipi neipi yekuzorora mukurapa kwako, uye kwevhiki ina mushure mekupedzisira kwako.

Usagovana lenalidomide nemumwe munhu, kunyangwe munhu ane zviratidzo zvakafanana zvauinazvo.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro RezveMishonga) paunotanga kurapwa nelenalidomide uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs), webhusaiti yemugadziri, kana REVLIMID REMS webhusaiti chirongwa (http://www.revlimidrems.com) Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekutora lenalidomide.

Kune varwere vechikadzi:

Kana iwe uchigona kuve nepamuviri, iwe uchafanirwa kusangana nezvimwe zvinodikanwa panguva yekurapa kwako nelenalidomide.Iwe unofanirwa kushandisa maviri anogamuchirwa mafomu ekudzivirira kuberekwa kwemavhiki mana usati watanga kutora lenalidomide, panguva yekurapwa kwako, kusanganisira panguva dzachiremba paanokuudza kuti umbomira kutora lenalidomide, uye kwemavhiki mana mushure mekupedzisira dosi. Chiremba wako anokuudza kuti ndedzipi nzira dzekudzivirira kuberekwa dzinogamuchirwa uye anokupa ruzivo rwakanyorwa nezve kudzora kubereka. Iwe unofanirwa kushandisa aya maviri maitiro ekudzivirira kuberekwa nguva dzese kunze kwekunge iwe uchigona kuvimbisa kuti hauzove nehukama hwepabonde nemunhurume kwemavhiki mana usati warapwa, panguva yekurapwa kwako, panguva ipi neipi yekukanganisa pakurapa kwako, uye kwevhiki ina muyero wako wekupedzisira.

Kana iwe ukasarudza kutora lenalidomide, ibasa rako kudzivirira kubata pamuviri kwemavhiki mana zvisati zvaitika, panguva, uye kwemasvondo mana mushure mekupedzisira kwako. Iwe unofanirwa kunzwisisa kuti chero chimiro chekudzivirira kuberekwa chinogona kukundikana. Naizvozvo, zvakakosha kuti udzikise njodzi yekubata netsaona uchishandisa nzira mbiri dzekuzvarwa. Udza chiremba wako kana iwe usinganzwisise zvese zvawakaudzwa nezve kudzora kuberekwa kana iwe usingafunge kuti iwe unozogona kushandisa maviri maitiro ekudzivirira kubereka nguva dzese.

Iwe unofanirwa kuve nemaviri asina kunaka ekuedzwa kwepamuviri usati watanga kutora lenalidomide. Iwe zvakare unofanirwa kuongororwa kuti une nhumbu murabhoritari pane dzimwe nguva panguva yekurapwa kwako. Chiremba wako anokuudza iwe nguva uye kupi kwaunofanira kuve nemiedzo iyi.

Regedza kutora lenalidomide uye danaidza chiremba wako ipapo ipapo kana iwe uchifunga kuti une nhumbu, unosuwa kuenda kumwedzi, une kubuda kweropa zvisina kujairika, kana kuita bonde usingashandise nzira mbiri dzekudzivirira kuberekwa. Kana iwe ukava nepamuviri panguva yekurapwa kwako kana mukati memazuva makumi matatu mushure mekurapwa kwako, chiremba wako anozobata chirongwa cheREVLIMID REMS, iyo inogadzira lenalidomide, uye Chikafu neDrug Administration (FDA). Iwe zvakare uchataura nachiremba anonyanya kugadzirisa matambudziko panguva yekuzvitakura anogona kukubatsira kuita sarudzo dzakanakira iwe nemwana wako. Ruzivo nezve hutano hwako uye hutano hwemwana wako hunoshandiswa kubatsira vanachiremba kudzidza zvakawanda nezve mhedzisiro yelenalidomide pane vacheche vasati vazvarwa.

Kune varwere vevarume:

Lenalidomide iripo mumurume wako paunotora mushonga uyu. Unofanira kugara uchishandisa kondomu reratex, kunyangwe iwe uine vasectomy (kuvhiyiwa kunotadzisa murume kukonzera nhumbu), pese paunosangana pabonde nemukadzi ane nhumbu kana anokwanisa kuve nepamuviri paunenge uchitora lenalidomide, panguva ipi neipi yekuzorora pakurapa kwako, uye kwevhiki ina mushure mekupedzisira kwako. Udza chiremba wako kana ukaita zvepabonde nemukadzi usingashandisi kondomu kana kana mumwe wako achifunga kuti anogona kuva nepamuviri panguva yekurapwa kwako nelenalidomide.

Usape urume paunenge uchitora lenalidomide, panguva ipi neipi yekuzorora mukurapa kwako, uye kwevhiki ina mushure mekupedzisira kwako.

Dzimwe njodzi dzekutora lenalidomide:

Lenalidomide inogona kukonzera kuderera kwenhamba yemamwe marudzi emasero eropa mumuviri wako. Chiremba wako anozoraira bvunzo dzemarabhoritari nguva dzese pakurapwa kwako kuti uone kuwanda kwemasero eropa. Chiremba wako anogona kudzikisira muyero wako, kukanganisa kurapwa kwako, kana kukubata iwe nemimwe mishonga kana kurapwa kana kuderera kwemasero ako eropa kwakanyanya. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera, udza chiremba wako nekukurumidza: huro, fivha, kutonhora, uye zvimwe zviratidzo zvehutachiona; kupwanya kuri nyore kana kubuda ropa; maronda ekubuda ropa; kana kubuda ropa mumhino.

Kana iwe uri kutora lenalidomide ne dexamethasone kurapa yakawandisa myeloma, kune njodzi yakawedzera yekuti unozokura ropa rinovhara mugumbo rako rinogona kufamba nemuropa kuyerera kumapapu ako, kana kurwara nemoyo kana sitiroko. Chiremba wako anogona kuraira imwe mishonga kuti itorwe pamwe nelenalidomide kudzikisa njodzi iyi. Udza chiremba wako kana iwe uchisvuta, kana iwe wakambove neropa rakakomba kugwamba, uye kana iwe kana wakambove uine yakakwira BP kana huwandu hwakakwira hwemafuta muropa rako. Uyezve udza chiremba wako nezve yese mishonga yauri kutora nekuti mimwe mishonga inogona kuwedzera njodzi yekuti unozogadzira ropa rinogwamba uchitora lenalidomide ine dexamethasone inosanganisira darbepoetin (Aranesp), epoetin alfa (Epogen, Procrit), uye mishonga ine estrogen yakadai hormone kutsiva kurapa kana mahormone ekudzivirira kubata pamuviri (mapiritsi ekudzora kubereka, zvigamba, mhete, zvigunwe, kana majekiseni). Kana ukasangana nechimwe chezviratidzo zvinotevera, udza chiremba wako nekukurumidza: kufema kwekufema; kurwadziwa kwepfupa kunogona kupararira kumaoko, mutsipa, musana, shaya, kana dumbu; kukosora; kutsvuka kana kuzvimba muruoko kana gumbo; vangadikitira; kusvotwa; kurutsa; kukurumidza kushaya simba kana kupera simba, kunyanya kune rumwe rutivi rwemuviri; kurwadziwa nemusoro; kuvhiringidzika; kana kunetseka nemaonero, kutaura, kana kuenzanisa.

Lenalidomide inoshandiswa kurapa imwe mhando yeiyo myelodysplastic syndrome (boka remamiriro ezvinhu umo mwongo wemapfupa unoburitsa masero eropa ayo ari kusakara uye asingaburitse masero eropa akakwana). Lenalidomide inoshandiswa zvakare pamwe ne dexamethasone kurapa vanhu vane yakawanda myeloma (rudzi rwekenza yemongo wemapfupa). Inoshandiswawo kurapa vanhu vane myeloma yakawanda mushure mehematopoietic stem-cell transplant (HSCT; maitiro umo mamwe masero eropa anobviswa mumuviri uye odzokera mumuviri). Lenalidomide inoshandiswawo kurapa vanhu vane mantle cell lymphoma (gomarara rinokurumidza kukura iro rinotanga mumasero ezvirwere zvemuviri) avo vakarapwa ne bortezomib (Velcade) uye mumwe mumwe mushonga. Lenalidomide haifanire kushandiswa kurapa vanhu vane chirwere chisingaperi chine lymphocytic leukemia (rudzi rwekenza yemasero machena eropa ayo anoramba achiwedzera zvishoma nekufamba kwenguva) kunze kwekunge vari kutora chikamu mukuyedzwa kwekiriniki (ongororo yekudzidza kuti uone kana mushonga ungashandiswa zvakachengeteka uye zvinobudirira kurapa imwe mamiriro). Lenalidomide iri mukirasi yemishonga inonzi immunomodulatory agents. Inoshanda nekubatsira iyo mwongo wemapfupa kugadzira maseru eropa akajairwa uye nekuuraya masero asina kujairika mumongo wepfupa.

Lenalidomide inouya sekapuleti kutora nemuromo. Kana lenalidomide ichishandiswa kurapa myelodysplastic syndrome, inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Kana lenalidomide ichishandiswa kurapa akawanda myeloma kana mantle cell lymphoma, inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva pazuva kwemazuva makumi maviri nerimwe ekutanga ezuva makumi maviri nemasere. Kana lenalidomide inoshandiswa kurapa myeloma yakawanda mushure meHSCT, inowanzo kutorwa pamwe kana pasina chikafu kamwe zuva nezuva kwemazuva makumi maviri nemasere ezuva makumi maviri nemasere. Iyo 28-yemazuva kutenderera regimen inogona kudzokororwa sezvakakurudzirwa nachiremba wako zvichienderana nemhinduro yemuviri wako kumushonga uyu. Tora lenalidomide panenge panguva imwechete yezuva zuva rega rega raunotora. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora lenalidomide chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza macapsule akazara nemvura yakawanda; usazvityora, kana kuzvitsenga, kana kuvhura. Bata ma capsules zvishoma sezvinobvira. Kana iwe ukabata rakaputsika lenalidomide capsule kana mushonga uri muiyo capsule, geza iyo nzvimbo yemuviri wako nesipo nemvura. Kana mushonga uri muhombodo ukapinda mumuromo mako, mumhino, kana maziso, geza nemvura yakawanda.

Chiremba wako angangoda kukanganisa kurapwa kwako kana kudzikisa dosi yako kana iwe ukawana mamwe mhedzisiro. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako nelenalidomide.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora lenalidomide,

• udza chiremba wako uye wemishonga kana uri weergoria kune lenalidomide, chero mimwe mishonga, kana chimwe chezvinhu zvinosanganiswa mumalenisomide capsules. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa mune CHINOKOSHA CHENYENZO chikamu uye digoxin (Lanoxin). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kana iwe uine lactose isingashiviriri uye kana iwe uine kana wakambove neitsvo, utachiona, kana chirwere chechiropa. Uyewo udza chiremba wako kana iwe wakambotora thalidomide (Thalomid) uye wakagadzira kuputika panguva yekurapa kwako.
• udza chiremba wako kana iwe uchiyamwisa kana uri kuronga kuyamwisa.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Kana anga ave asingasviki maawa gumi nemaviri kubvira pawakange wakarongerwa kutora dosi, tora iyo yakarasika dosi nekukurumidza kana uchinge uchayeuka izvozvo. Kana anga ave anopfuura maawa gumi nemaviri, svetuka iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Lenalidomide inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• kuvimbiswa
• kurwadziwa nemudumbu
• kurasikirwa nenzara
• kuonda
• kushaya simba
• dzungu
• chinja mukugona kuravira
• kurwadziwa kana kupisa kwerurimi, muromo, kana huro
• kuderera kwekubata
• kupisa kana kurira mumaoko kana mutsoka
• kunetseka kurara kana kuramba wakarara
• kuora mwoyo
• kubatana, mhasuru, bhonzo, kana kurwadziwa musana
• zvinorwadza, kazhinji, kana kukurumidza kuita weti
• vangadikitira
• ganda rakaoma
• bvudzi risina kujairika kukura muvakadzi
• kuzunza kusingadzoreki nhengo yemuviri
• kuderera mukushuva pabonde kana kugona

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kuzvimba kwechiso, huro, rurimi, miromo, maziso, maoko, maoko, tsoka, makumbo, kana makumbo ezasi
• kunetseka kufema kana kumedza
• hoarseness
• nekukurumidza, kunonoka, kurovera, kana kurova kwemoyo zvisina kujairika
• pfari
• mapundu
• kurwadziwa kweganda
• kuputika, kubvisa, kana kudurura ganda
• kuzvimba gland mumutsipa
• tsandanyama
• kurwadziwa kumusoro kwepamusoro chikamu chedumbu
• yero yeganda kana maziso
• weti yakasviba
• kuneta
• reropa, rine makore, kana rinorwadza kuita weti
• kuwedzera kana kuderera kuita weti

Kana iwe uri kutora lenalidomide kurapa yakawandisa myeloma uye iwe zvakare unogashira melphalan (Alkeran) kana reropa stem sero kuisirwa, iwe unogona kuve nenjodzi yakakwira yekuvandudza kanzira nyowani. Taura nachiremba wako nezve njodzi dzekutora lenalidomide. Chiremba wako achakutarisa kuti uwane cancer nyowani panguva yekurapa kwako nelenalidomide.

Lenalidomide inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchitora mushonga uyu.

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Dzorera chero mishonga yechinyakare kana isingachadiwe kuna chiremba wako, chemishonga iyo yakupa iwe mushonga, kana iye anogadzira.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

• kuvava
• mikoko
• mapundu

Chengetedza zvese zvakagadzwa nachiremba wako. Chiremba wako anogona kuraira mimwe bvunzo usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune lenalidomide.

Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Revlimid^®