Tocilizumab jekiseni

Zvemukati

• Tocilizumab jekiseni rinoshandiswa roga kana musanganiswa nemimwe mishonga kugadzirisa zviratidzo zvemamwe marudzi eArthritis uye mamwe mamiriro anosanganisira:
• Usati wagamuchira tocilizumab jekiseni,
• Tocilizumab jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Kushandisa jekiseni tocilizumab kunogona kudzikisira kugona kwako kurwisa hutachiona kubva kubhakitiriya, mavairasi, uye fungi uye kuwedzera njodzi yekuti uchawana hutachiona hwakakomba kana hunotyisa hunogona kupararira nemuviri. Udza chiremba wako kana iwe uchiwanzowana chero hutachiona hutachiona kana kana uine kana uchifunga kuti unogona kunge uine chero hutachiona ikozvino. Izvi zvinosanganisira hutachiona hushoma (sekucheka kana maronda akavhurika), hutachiona hunouya nekuenda (senge maronda anotonhora), uye hutachiona husingaperi husingaendi. Uyezve udza chiremba wako kana iwe kana wakambove nechirwere cheshuga, hutachiona hwehutachiona hwehutachiwana hweHIV, kana chero mamiriro ezvinhu anokanganisa immune system yako, uye kana uchirarama, wakamborarama, kana kuenda kunzvimbo dzakadai semipata yeOhio neMississippi uye kumaodzanyemba kwakadziva kumadokero uko kwakanyanya hutachiona hutachiona hwakawanda. Kumbira chiremba wako kana iwe usingazive kana izvi hutachiona zvakajairika munharaunda yako. Uyezve udza chiremba wako kana uri kutora: abatacept (Orencia); adalimumab (Humira); anakinra (Kineret); certolizumab (Cimzia); etanercept (Enbrel); golimumab (Simponi); infliximab (Remicade); mishonga inodzvinyirira immune system yakadai sa azathioprine (Azasan, Imuran), cyclosporine (Gengraf, Neoral, Sandimmune), methotrexate (Otrexup, Trexall, vamwe), sirolimus (Rapamune), uye tacrolimus (Prograf); muromo steroid senge dexamethasone, methylprednisolone, uye prednisone (Rayos); kana rituximab (Rituxan). Kana iwe ukasangana nechimwe cheanotevera zviratidzo, dana chiremba wako nekukurumidza: fever; chills; vangadikitira; kunetseka kufema; huro inorwadza; kukosora; kuonda; manyoka; kurwadziwa mudumbu; ropa muhomwe; kuneta kwakanyanya; tsandanyama aches; inodziya, tsvuku, kana inorwadza ganda; maronda paganda kana mumuromo; kusvira paunenge uchiita weti; kugara uchiita weti; kana zvimwe zviratidzo zvehutachiona.

Unogona kutapukirwa netibhii (TB; rudzi rwehutachiona hwemapapu) kana hepatitis B (rudzi rwechirwere chechiropa) asi usina zviratidzo zvechirwere. Mune ino kesi, tocilizumab jekiseni inogona kuwedzera njodzi yekuti hutachiona hwako huchawedzera uye uchaita zviratidzo. Chiremba wako achaita ongororo yeganda kuti aone kana uine hutachiona hweTB husingaite uye anogona kuraira kuongororwa kweropa kuti aone kana uine hutachiona hwehepatitis B. Kana zvichidikanwa, chiremba wako achakupa mishonga yekurapa hutachiona usati watanga kushandisa jekiseni tocilizumab. Udza chiremba wako kana wakambove neTB kana hepatitis B, kana wakashanyira nyika ipi neipi iyo TB yakajairika, kana kana wakambove pedyo nemunhu ane TB. Kana iwe uine chero anotevera ezviratidzo zveTB, kana kana ukaita chero cheizvi zviratidzo panguva yekurapwa kwako, fonera chiremba wako nekukasira: kukosora, kurwadziwa pachipfuva, kukosora ropa kana mamasi, kushaya simba kana kuneta, kuonda, kurasikirwa nechido, kutonhora, kupisa muviri, kana kudikitira usiku. Zvakare fonera chiremba wako nekukasira kana uine chimwe chezviratidzo zvehepatitis B kana kana iwe uchikura chimwe chezviratidzo izvi panguva kana mushure mekurapwa kwako: kuneta zvakanyanya, kuita yero kweganda kana maziso, kurasikirwa nechido, kuda kurutsa, kurutsa, tsandanyama aches, weti yakasviba, kufamba-kweuvara-ura kufamba, fivha, kutonhora, kurwadziwa mudumbu, kana kuputika.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anoongorora hutano hwako zvakanyatsonaka kuti ave nechokwadi chekuti haugadzi hutachiona hwakakomba. Chiremba wako acharaira mamwe marabhoritari ekuongorora usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune tocilizumab jekiseni.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa nejekiseni ye tocilizumab uye pese paunogamuchira mishonga. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekushandisa tocilizumab jekiseni.

Tocilizumab jekiseni rinoshandiswa roga kana musanganiswa nemimwe mishonga kugadzirisa zviratidzo zvemamwe marudzi eArthritis uye mamwe mamiriro anosanganisira:

• rheumatoid arthritis (mamiriro umo muviri unorwisa majoini ayo, zvichikonzera marwadzo, kuzvimba, uye kurasikirwa nebasa) muvanhu vasina kubatsirwa nedzimwe hosha-dzinochinja antirheumatic zvinodhaka (DMARDs),
• giant cell arteritis (mamiriro anokonzera kuzvimba kwemitsipa yeropa, kunyanya mumusoro nemusoro),
• polyarticular juvenile idiopathic arthritis (PJIA; mhando yehudiki arthritis inobata majoini mashanu kana anopfuura mukati memwedzi mitanhatu yemamiriro acho, zvichikonzera kurwadziwa, kuzvimba, uye kurasikirwa kwebasa) muvana vane makore maviri ekuberekwa kana kupfuura.
• systemic vechidiki idiopathic arthritis (SJIA; mamiriro muvana anokonzeresa kuzvimba munzvimbo dzakasiyana dzemuviri, zvichikonzera kupisa, kurwadza kwemajoini uye kuzvimba, kurasikirwa nebasa, uye kunonoka mukukura nekusimudzira) muvana vane makore maviri ekuberekwa kana kupfuura,
• cytokine release syndrome (yakaoma uye inogona kutyisidzira hupenyu) inoitika muvakuru uye vana makore maviri ekuberekwa kana kupfuura mushure mekugamuchira mamwe immunotherapy infusions.

Tocilizumab jekiseni iri mukirasi yemishonga inonzi interleukin-6 (IL-6) receptor inhibitors. Inoshanda nekudzivirira chiitiko che interleukin-6, chinhu chiri mumuviri chinokonzera kuzvimba.

Jekiseni reTocilizumab rinouya semhinduro (mvura) kuiswa jekiseni (mutsinga) muruoko rwako nachiremba kana mukoti muhofisi yezvokurapa kana kuchipatara chipatara chevarwere kana sechirin'i yakasarudzwa kujekesa pasi peganda) wega pauri kumba. Apo tocilizumab inopiwa intravenously kurapa rheumatoid arthritis kana polyarticular yevana vechidiki idiopathic arthritis, inowanzo kupihwa kamwe chete pavhiki ina. Kana tocilizumab ikapihwa intravenously kurapa systemic vechidiki idiopathic arthritis, inowanzo kupihwa kamwe chete pa1 kana maviri mavhiki. Kana tocilizumab ikapihwa intravenously kurapa cytokine kuburitsa chirwere, inowanzo kupihwa kamwe, asi kusvika pamamwe matatu madhizaini anogona kupihwa angangoita maawa masere akaparadzaniswa. Zvinotora inenge 1 awa kuti iwe ugamuchire yako dosi ye tocilizumab jekiseni mukati. Apo tocilizumab inopihwa pasi pechirapa kurapa rheumatoid arthritis kana hofori cell arteritis, inowanzo kupihwa kamwe chete pasvondo kana kamwe kamwe pasvondo.

Iwe uchagamuchira yako yekutanga subcutaneous dose ye tocilizumab jekiseni muhofisi yechiremba wako. Kana iwe uchizove jekiseni tocilizumab jekiseni unozviisa wega pamba kana uine shamwari kana hama yekubainira iwe mushonga, chiremba wako achakuratidza kana iye munhu achange achipinza mushonga kuti anoijowa sei. Iwe nemunhu anenge achizobaya mushonga unofanirawo kuverenga mirairo yakanyorwa yekushandisa inouya nemushonga.

Maminitsi makumi matatu usati wagadzirira kubaya jekiseni tocilizumab, unofanirwa kubvisa mishonga kubva mufiriji, kuitora kunze kwekatoni rayo, uye kuitendera kuti itonhe tembiricha yemukati. Paunenge uchibvisa sirinji yakasarudzika kubva mubhokisi, chenjera kuti usabata zvigunwe zvekutanga pane sirinji. Usaedze kudziya mushonga nekuupisa mu microwave, uchiisa mumvura inodziya, kana neimwe nzira.

Usabvise kapu kubva pasiringi yakasarudzwa apo mushonga uchidziya. Iwe unofanirwa kubvisa chivharo kwete anopfuura maminetsi mashanu usati wabaya mushonga. Usatsiva chivharo kana wabvisa. Usashandise jekiseni kana iwe ukariwisira pasi.

Tarisa sirinji yakasarudzwa kuti uve nechokwadi chekuti zuva rekupera rakadhindwa papakeji harisati rapfuura, Wakabata sirinji ine tsono yakavharidzirwa yakanongedzera pasi, tarisa zvakanyanya pamvura irimo sirinji. Mvura yacho inofanirwa kuve yakajeka kana kuchena yero uye haifanire kunge iine makore kana kuvezwa kana kuva nemapundu kana zvidimbu. Fonera wemishonga wako kana paine chero matambudziko nepakeji kana sirinji uye usabaise mushonga.

Unogona jekiseni tocilizumab jekiseni kumberi kwezvidya kana chero padumbu rako kunze kweguvhu rako (dumbu bhatani) uye nharaunda yacho 2 inches kutenderedza. Kana mumwe munhu ari kubaya mushonga wako, iyo yekukunze kwemaoko ekumusoro zvakare inogona kushandiswa. Usapinda jekiseni mushonga muganda rakapfava, rakapwanywa, rakatsvuka, rakaomarara, kana risina kugadzikana, kana rine mavanga, mamota, kana maronda. Sarudza imwe nzvimbo nguva imwe neimwe paunobaya mushonga, inokwana 1 inch kure kubva panzvimbo yawakamboshandisa. Kana iyo yakazara dose isina kujowa, fonera chiremba wako kana wemishonga.

Usashandise tocilizumab yakatemwa majekiseni uye usadzorere majekiseni mushure mekushandisa. Rasa majekiseni akamboshandiswa mumudziyo unodzivira uye bvunza wemishonga kuti ungarasa sei mudziyo wacho.

Tocilizumab jekiseni inogona kubatsira kudzora zviratidzo zvako, asi hazvizorape mamiriro ako. Chiremba wako anokucherekedza nokungwarira kuti aone kuti tocilizumab jekiseni inoshanda sei kwauri. Chiremba wako anogona kugadzirisa dhizaini yako kana kunonoka kurapwa kwako kana iwe uine zvimwe zvachinja mune ako marabhoritari mhedzisiro. Zvakakosha kuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati wagamuchira tocilizumab jekiseni,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune tocilizumab, chero mimwe mishonga, kana chero chinhu chinosanganiswa mujekiseni ye tocilizumab. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa muchikamu CHINOKOSHA CHENYENZO uye chero ipi yeanotevera: anticoagulants ('blood thinner') senge warfarin (Coumadin, Jantoven); asipurini uye mamwe asiri -steroidal anti-anogumbura zvinodhaka (NSAIDs) senge ibuprofen (Advil, Motrin, vamwe) uye naproxen (Aleve, Naprosyn, vamwe); cholesterol-kudzikisa mishonga (masitamin) senge atorvastatin (Lipitor, muCaduet), lovastatin (Altoprev, muAdvicor), uye simvastatin (Zocor, muVytorin); mishonga yekudzivirira pamuromo (mapiritsi ekudzivirira kubereka); kana theophylline (Elixophyllin, Theo-24, vamwe). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana ne tocilizumab jekiseni, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kana iwe wakambove kana wakambove nekenza; diverticulitis (homwe diki mumucheka wemuhomba muhombe unogona kupiswa); maronda mudumbu kana mumatumbu; cholesterol yakawanda uye triglycerides; chero mamiriro ezvinhu anokanganisa hurongwa hwemitsipa senge multiple sclerosis (MS; chirwere umo tsinga dzisingashande nemazvo uye vanhu vanogona kushaya simba, kupera simba, kurasikirwa kwekubatana kwetsandanyama uye matambudziko nekuona, kutaura, uye kudzora dundira) kana kusingaperi kuzvimba demyelinating polyneuropathy (CIDP; kusagadzikana kwema immune immune uye masystem masisitimu); kana chirwere chechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri iwe uchinge uchigamuchira tocilizumab jekiseni, fonera chiremba wako.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikugamuchira jekiseni re tocilizumab.
• bvunza chiremba wako kana iwe uchifanira kupihwa chero majekiseni usati watanga kurapwa kwako ne tocilizumab jekiseni. Kana zvichikwanisika, majekiseni ese evana anofanirwa kukwidzwa kusvika parinhasi vasati vatanga kurapwa. Hauna majekiseni panguva yekurapa kwako pasina kutaura nachiremba wako.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Kana iwe ukarasikirwa musangano wekugamuchira tocilizumab infusion, fonera chiremba wako.

Kana iwe ukakanganwa jekiseni subcutaneous dosi ye tocilizumab, jekesa iyo yakarasika dosi nekukurumidza kana uchinge uchayeuka izvozvo. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usapinda jekiseni repaviri kuti uwane iyo yakarasika. Fonera chiremba wako kana wemishonga kana iwe usingazive nguva yekubaya jekiseni tocilizumab.

Tocilizumab jekiseni inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• kumhanya mhino kana kuhotsira
• kutsvuka, kuchenesa, kurwadziwa, kana kuzvimba munzvimbo yaibayiwa tocilizumab

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• mapundu
• kufashaira
• mikoko
• kuvava
• kuzvimba kwemaziso, kumeso, miromo, rurimi, huro, maoko, maoko, tsoka, makumbo, kana makumbo ezasi
• kunetseka kufema kana kumedza
• kurwadziwa pachipfuva
• dzungu kana kupera simba
• fivha, kuenderera mudumbu-marwadzo, kana shanduko muhunhu maitiro
• yero maziso kana ganda; kurudyi kumusoro kwepamuviri kurwadziwa; kupwanya kusingatsanangurike kana kubuda ropa; kurasikirwa nenzara; kuvhiringidzika; weti yero kana yeruvara-shava; kana zvituru zvakacheneruka

Tocilizumab inogona kuwedzera njodzi yekuvandudza mamwe marudzi ekenza. Taura nachiremba wako nezve njodzi dzekugamuchira uyu mushonga.

Tocilizumab jekiseni inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika paunenge uchigamuchira mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza mishonga iyi mupakeji yaakauya mukati, kure nechiedza, yakavharwa, uye isingasviki nevana. Chengetera tocilizumab jekiseni mufiriji, asi usazviisa chando. Chengetedza majekiseni akafanirwa akaoma. Rasa chero mishonga yechinyakare kana isingachadiwe. Taura nachiremba wako nezve kuraswa kwakanaka kwemishonga yako.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Bvunza wako wemishonga chero mibvunzo iwe unayo nezve tocilizumab jekiseni.

Usarega mumwe munhu achishandisa mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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