Bedaquiline

Zvemukati

• Usati watora bedaquiline,
• Bedaquiline inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Bedaquiline inongofanirwa kushandiswa kurapa vanhu vane tibhii inodzivirira mishonga yakawanda (MDR-TB; chirwere chakakomba chinokanganisa mapapu uye zvimwe zvikamu zvemuviri uye chisingarapike nemaviri emishonga inowanzo shandiswa bata mamiriro acho) apo kumwe kurapa kusingashandiswe. Muchidzidzo chemakiriniki, kwaive nekufa kwakawanda pakati pevanhu vaitora bedaquiline kupfuura vanhu vasina kutora mushonga. Zvisinei, MDR-TB chirwere chinotyisidzira hupenyu, saka iwe nachiremba wako mungasarudza kuti munofanira kurapwa ne bedaquiline kana mamwe marapirwo asingakwanise kushandiswa.

Bedaquiline inogona kukonzera zvakakomba kana kutyisidzira hupenyu mumoyo wako mutinhimira. Iwe unozofanirwa kuve neiyo electrocardiogram (ECG; bvunzo inoyera chiitiko chemagetsi chemwoyo) usati warapwa uye kakawanda panguva yekurapwa kwako kuti uone kuti uyu mushonga unokanganisa sei moyo wako mutinhimira. Udza chiremba wako kana iwe kana chero munhu mumhuri mako akareba QT syndrome (chisingawanzoitika dambudziko remwoyo rinogona kukonzeresa kurova kwemoyo zvisina kufanira, kufenda, kana kufa kamwe kamwe) uye kana iwe kana wakambove nekurovera kana kusarongeka kwemoyo, gland isingashande, yakaderera mwero wecalcium, magnesium, kana potasium muropa rako, kutadza kwemoyo, kana chirwere chemwoyo chazvino. Udza chiremba wako uye wemishonga kana uri kutora ipi yemishonga inotevera: azithromycin (Zithromax), ciprofloxacin (Cipro), clarithromycin (Biaxin), clofazimine (Lamprene), erythromycin (EES, E-Mycin, Erythrocin), gemifloxacin (Factive) , levofloxacin (Levaquin), moxifloxacin (Avelox), uye telithromycin (Ketek). Kana iwe ukava nekukurumidza kana kusajairika kurova kwemoyo kana kana iwe ukapera simba, dana chiremba wako nekukasira.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa ne bedaquiline uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekutora bedaquiline.

Bedaquiline inoshandiswa pamwe chete nemimwe mishonga mitatu yekurapa tibhii inorwisa mishonga yakawanda (MDR-TB; chirwere chakakomba chinokanganisa mapapu uye zvimwe zvikamu zvemuviri uye chisingarapike nemimwe mishonga inowanzo shandiswa kurapa mamiriro) muvanhu vakuru uye vana makore mashanu zvichikwira avo vanorema ingangoita 33 lbs (15 kg) iyo yakabata mapapu. Bedaquiline haifanire kushandiswa kurapa TB inonyanya kubata dzimwe nhengo dzemuviri. Bedaquiline iri mukirasi yemishonga inonzi anti-mycobacterials. Inoshanda nekuuraya hutachiona hunokonzera MDR-TB.

Bedaquiline inouya sehwendefa kutora nemuromo nemvura. Inowanzo kutorwa nechikafu kamwe chete pazuva kwevhiki mbiri uyezve katatu pavhiki kwemavhiki makumi maviri nemaviri. Paunenge uchitora bedaquiline katatu pasvondo, rega kanenge maawa makumi mana nemasere pakati pemadhosi. Tora bedaquiline panguva imwe chete yezuva uye nemazuva akafanana evhiki vhiki imwe neimwe. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora bedaquiline chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kana iwe kana mwana wako musingakwanise kumedza iyo 20 mg piritsi yakazara, munogona kuvapwanya nepakati pane mamaki mamaki.

Kana iwe kana mwana wako musingakwanise kumedza mapiritsi e20 mg akazara kana nehafu, mapiritsi anogona kunyungudika mu 1 teaspoon (5 mL) yemvura mukapu yekumwa (kwete anopfuura mapiritsi mashanu). Unogona kunwa musanganiswa uyu nekukasira kana kuti kuti zviitwe zviri nyore, wedzera kana 1 teaspoon (5 mL) yemvura yekuwedzera, chigadzirwa chemukaka, muto weapuro, jisi reorenji, cranberry muto, kana chinwiwa chine kaboni, kana neimwe nzira kuwedzerwa. Wobva wamedza musanganiswa wese ipapo. Mushure mekutora dosi, sukurudza kapu nemari shoma yekuwedzera yemvura kana chinyoro chikafu woitora nekukasika kuti uve nechokwadi chekuti unogashira muyero wese. Kana iwe uchida anopfuura mashanu mashanu mg mg-mapiritsi ebedaquiline, dzokorora matanho ari pamusoro kusvikira iwe wasvika pane yako yakatarwa dosi.

Neimwe nzira, kuti zvive nyore kumedza, unogona zvakare kupwanya mapiritsi makumi maviri emigodhi uye wobva wawedzera kuchikafu chinyoro senge yogati, maapuloauce, bhanana yakakwenenzverwa, kana oatmeal uye kumedza musanganiswa wese ipapo. Mushure mekutora iyo dosi, wedzera shoma shoma yekuwedzera chinyoro chikafu uye utore icho nekukurumidza kuti uve nechokwadi chekuti unogashira iro rose dosi.

Kana iwe uine nasogastric (NG) chubhu, chiremba wako kana wemishonga anotsanangura kuti ungagadzirira sei bedaquiline kupa kuburikidza neNG tube.

Ramba uchitora bedaquiline kudzamara wapedza kunyorerwa uye usarasikirwa nemadhosi, kunyangwe kana uchinzwa zvirinani. Kana iwe ukamira kutora bedaquiline nekukurumidza kana kusvetuka madosi, hutachiona hwako hunogona kusarapwa zvakakwana uye hutachiona hunogona kuramba husingaurayiwi nemishonga inorwisa mabhakitiriya. Izvi zvichaita kuti hutachiona hwako huome kurapa mune ramangwana. Kuita kuti zvive nyore kwauri kutora mishonga yako yese sekurairwa, iwe unogona kutora chikamu muchirongwa chekurapa chakanyatsocherechedzwa. Muchirongwa ichi, mushandi wezvehutano anokupa wega wega mushonga uye anozotarisa paunenge uchimedza mushonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora bedaquiline,

• udza chiremba wako uye wemishonga kana iwe uri weergoria kune bedaquiline, chero mimwe mishonga, kana chero chinhu chinowanikwa mumatafura e bedaquiline. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, uye zvinovaka muviri zvaunotora kana kuronga kutora. Ive neshuwa yekutaura mishonga yakanyorwa mune CHINOKOSHA CHENYENZO chikamu uye chero cheanotevera: carbamazepine (Equetro, Tegretol, Teril, vamwe); mimwe mishonga yehutachiona hwehutachiona hwehutachiona hweHIV hunosanganisira efavirenz (Sustiva, muAtripla), indinavir (Crixivan), lopinavir (muKaletra), nelfinavir (Viracept), ritonavir (Norvir, muCaletra, muViekira Pak) itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); nefazodone; phenobarbital; phenytoin (Dilantin); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, muRifamate, muRifater); uye rifapentine (Priftin). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kusangana ne bedaquiline, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana wakambove neHIV, kana chiropa kana hosha yeitsvo.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe ukava nepamuviri iwe uri kutora bedaquiline, fonera chiremba wako. Kana iwe uri kuyamwisa, udza chiremba wako kana mwana wako ane maziso eyero kana ganda kana achichinja muvara weti yavo kana chigaro.
• dzivisa kunwa zvinwiwa zvinodhaka paunenge uchitora bedaquiline. Kunwa doro kunowedzera njodzi yekuti iwe uchave nemhedzisiro mhedzisiro kubva bedaquiline.

Taura nachiremba wako nezve kudya mazambiringa uye kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.

Kana iwe ukarasikirwa neiyo dhivhisi mukati memavhiki maviri ekutanga ekurapwa kwako, ruka iro rakarasika dosi uye ramba uchiita yako yenguva dzose dosing chirongwa. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana iwe ukarasikirwa nedosi kubva pavhiki 3 mukati memavhiki akasara ekurapwa kwako, tora iyo yakarasika dhiza nechikafu nekukurumidza kana uchinge uchinge uchirangarira uye woenderera neako katatu nguva pasvondo dosing purogiramu. Ita shuwa kuti pane angangoita maawa makumi maviri nemana pakati pekutora iro rakarasika dhizaini uye rinotevera rakarongwa dosi. Usatore dhivhosi yakapetwa kaviri kuti uwane imwe yakarasika kana kutora zvinopfuura muyero wako wevhiki nezuva mumazuva manomwe.

Bedaquiline inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kurwadza kwemajoini
• musoro
• mapundu

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muchikamu CHINOKOSHA CHENYENZO, fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kuneta zvakanyanya
• kurasikirwa nenzara
• kusvotwa
• yero yeganda kana maziso
• weti yakasviba
• akajeka mavara matumbu kufamba
• marwadzo munzvimbo yepamusoro yekurudyi yemudumbu
• kupindwa nechando
• kukosora ropa
• kurwadziwa pachipfuva

Bedaquiline inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nechiedza, kupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Chengeta iyo desiccant (yekuomesa mumiriri) packet muhombodo yemushonga kuti mapiritsi aome.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari kuti atarise mhinduro yemuviri wako kune bedaquiline.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Sirturo^®