Pralsetinib

Zvemukati

• Usati watora pralsetinib,
• Pralsetinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muZVINONYANYA ZVINOKOSHA, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Pralsetinib inoshandiswa kurapa imwe mhando yekenza isiri-diki yemapapu kenza (NSCLC) muvakuru yakapararira kune dzimwe nhengo dzomuviri. Iyo inoshandiswa zvakare kurapa imwe mhando yekenza yehutachiona muvakuru uye vana vane makore gumi nemaviri ekuberekwa iri kuramba ichitowedzera kana iyo yapararira kune dzimwe nhengo dzemuviri. Pralsetinib inoshandiswa kurapa imwe mhando yekenza yehutachiona muvakuru uye vana vane makore gumi nemaviri zvichikwira iri kuramba ichitowedzera kana kuti yakapararira kune dzimwe nhengo dzemuviri uye isingakwanise kurapwa neayodini ine radioactive. Pralsetinib iri mukirasi yemishonga inonzi kinase inhibitors. Inoshanda nekudzivirira chiito chechimwe chinhu chinowanzoitika chinogona kudikanwa kubatsira maseru ekenza kuwanda.

Pralsetinib inouya sekapuleti kutora nemuromo. Inowanzo kutorwa kamwe chete zuva nezuva pane isina chinhu mudumbu, angangoita maawa maviri pamberi uye angangoita 1 awa mushure mekudya. Tora pralsetinib panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora pralsetinib chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kana iwe ukarutsa mushure mekutora pralsetinib, usatore imwe dosi. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako anogona kudzora dhizaini yako kana kwechinguva kana zvachose kumisa kurapwa kwako kana iwe ukawana mamwe mhedzisiro. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako ne pralsetinib.

Kumbira wemishonga wako kana chiremba kopi yemashoko emugadziri wemurwere.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora pralsetinib,

• udza chiremba wako uye wemishonga kana uri weergoria kune pralsetinib, chero mimwe mishonga, kana chero chinhu chinogadzirwa mu pralsetinib capsules. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: antifungal mishonga inosanganisira itraconazole (Onmel, Sporanox) uye ketoconazole; clarithromycin (muBiaxin); mimwe mishonga yeHIV yakadai seEfavirenz (Sustiva, muAtripla, Symfi), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, muKaletra, Viekira Pak), uye saquinavir (Invirase); oxcarbazepine (Oxtellar XR, Trileptal); phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos, muOseni, Duetact); rifabutin (Mycobutin); uye rifampin (Rifadin, Rimactane, muRifater). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana iwe wakambove kana uine matambudziko emapapu kana kufema kunze kwekenza yemapapu, matambudziko ekubuda ropa, kuwedzerwa kweropa, kana chirwere chechiropa.
• udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana kana iwe uchironga kubereka mwana. Pralsetinib inogona kukanganisa chiito chehomoni yekudzivirira kubata pamuviri (mapiritsi ekudzora kubereka, zvigamba, mhete, majekiseni, kana majekiseni), saka haufanire kushandisa izvi senzira yako chete yekudzivirira kubereka panguva yekurapwa kwako. Iwe unofanirwa kushandisa isiri-mahormone yekuberekwa senzira yekudzivirira (mudziyo unodzivirira urume kuti usapinda muchibereko sekondomu kana diaphragm). Kumbira chiremba wako kuti akubatsire kusarudza nzira yekudzivirira kuberekwa iyo ichakushandira iwe. Kana iwe uri munhukadzi, iwe uchafanirwa kuve nemimba yekubata usati watanga kurapwa, uye iwe unofanirwa kushandisa isiri-mahormone ekudzivirira kubereka kudzivirira kubata pamuviri panguva yekurapwa kwako uye kwemavhiki maviri mushure medosi yako yekupedzisira. Kana iwe uri murume uye mumwe wako achigona kuve nepamuviri, iwe unofanirwa kushandisa inoshanda kubereka kudzivirira kudzivirira kubata pamuviri panguva yekurapwa kwako uye kwevhiki rimwe mushure meyako yekupedzisira dosi. Iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume nevakadzi; zvisinei, haufanire kufunga kuti haugone kubata pamuviri kana kuti haugone kuitisa mumwe munhu nhumbu. Kana iwe kana mumwe wako ukava nepamuviri paunenge uchitora pralsetinib, danaidza chiremba wako. Pralsetinib inogona kukuvadza fetus.
• udza chiremba wako kana iwe uchiyamwisa kana kuronga kuyamwisa. Iwe haufanire kuyamwa uchi tora pralsetinib uye kwevhiki rimwe mushure mekupedzisira kwezita rako.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume nevakadzi. Taura nachiremba wako nezve njodzi dzekutora pralsetinib.
• kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora pralsetinib. Chiremba wako anogona kukuudza kuti usatore pralsetinib mazuva mashanu usati wavhiyiwa uye anokuudza nguva yekutanga kunwa mushonga zvakare.
• iwe unofanirwa kuziva kuti yako yeropa inogona kuwedzera panguva yekurapa kwako ne pralsetinib. Chiremba wako anozotarisa yako yeropa nekuchenjerera, uye anogona kupa mishonga yekurapa yakakwira BP kana ikakura
• iwe unofanirwa kuziva kuti iwe unogona kusangana ne tumor lysis syndrome (TLS; mamiriro anokonzereswa nekukurumidza kuparara kwekenza maseru ayo anogona kukonzera itsvo kutadza uye zvimwe zvinetswa) panguva yekurapwa kwako ne pralsetinib. Kuti ubatsire kudzikisa njodzi yako yekuona TLS, chiremba wako anogona kukukumbira kuti unwe mvura usati uye panguva yekurapa kwako, uye nguva yega yega dhosi rako parinowedzerwa. Uye zvakare, chiremba wako anokupa iwe mushonga wekutora usati watanga uye panguva yekurapa kwako kubatsira kudzivirira iyi divi mhedzisiro. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiona.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Tora dosi rakarasika pazuva rimwe chete nekukurumidza kana uchinge warangarira. Zvadaro, ramba uchiita dosing yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Pralsetinib inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• kuvimbiswa
• manyoka
• muromo wakaoma
• mhasuru kana kurwadziwa kwepfupa
• kuzvimba kwemaoko, makumbo, kana tsoka

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana izvo zvakanyorwa muZVINONYANYA ZVINOKOSHA, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kuvhiringidzika, kurwadziwa nemusoro, kufema kwekufema, dzungu, kana kurwadziwa pachipfuva
• fivha, kufema kwekufema, kana kukosora
• ganda rakachenuruka, kuneta, kana kufema kwekufema
• yero yeganda kana maziso, yakasviba-yeti weti, kubuda ropa kana kupwanya zviri nyore kupfuura zvakajairwa, kurasikirwa kwechido, kupera simba, kana kurwadziwa kurudyi kwedumbu nzvimbo.
• nhema uye yekumhara zvituru
• ropa dzvuku muzvituru
• kurutsa kweropa
• kurutsa zvinhu zvinoita kunge kofi nzvimbo
• kukosora ropa
• kubuda ropa zvisina kujairika kana kupwanya
• kubuda kweropa zvisina kujairika
• kazhinji mhino dzinobuda ropa
• Kukotsira, kuvhiringidzika, kutemwa nemusoro, kana kunetseka kutaura

Pralsetinib inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira bvunzo bvunzo usati warapwa kuti uone kana kenza yako inogona kurapwa ne pralsetinib. Chiremba wako anozorairawo kumwe kuongorora kwelebhu kare, panguva, uye mushure mekurapwa kwako kuti utarise mhinduro yemuviri wako kune pralsetinib.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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