Munyori: Gregory Harris
Zuva Rekusika: 16 Kubvumbi 2021
Gadziridza Zuva: 18 Mbudzi 2024
Anonim
Canagliflozin, Dapagliflozin, and Empagliflozin - Sodium Glucose Cotransporter Inhibitors
Vhidhiyo: Canagliflozin, Dapagliflozin, and Empagliflozin - Sodium Glucose Cotransporter Inhibitors

Zvemukati

Kanagliflozin inoshandiswa pamwe nekudya uye kurovedza muviri, uye dzimwe nguva nemimwe mishonga, kudzikisa shuga mumuropa muvanhu vane chirwere cheshuga cheshuga (mamiriro umo shuga yeropa yakanyanyisa nekuti muviri haugadzi kana kushandisa insulin zvakajairika). Kanagliflozin inoshandiswawo kudzikisa njodzi yekurohwa, kurohwa nemoyo, kana kufa kune vanhu vane chirwere cheshuga chechipiri pamwe nemoyo uye neropa chirwere chirwere. Canagliflozin inoshandiswawo kudzikisa njodzi yekuguma-chikamu cheitsvo chirwere, kuwedzera kweitsvo kushanda, kuda kuiswa muchipatara nekuda kwekutadza kwemoyo, uye kufa kwemoyo muvanhu vane rudzi rwechipiri chirwere cheshuga pamwe nechirwere cheitsvo chakakomba. Canagliflozin iri mukirasi yemishonga inonzi sodium-glucose co-transporter 2 (SGLT2) inhibitors. Iyo inoderedza shuga yeropa nekukonzera itsvo kubvisa yakawanda glucose mumurini. Kanagliflozin haina kushandiswa kurapa chirwere cheshuga cheshuga (mamiriro umo muviri usingaburitse insulin uye, nekudaro, haugone kudzora huwandu hweshuga muropa).


Nekufamba kwenguva, vanhu vane chirwere cheshuga uye shuga yakakwira muropa vanogona kukura zvakakomba kana kutyisidzira hupenyu, kusanganisira chirwere chemwoyo, sitiroko, matambudziko eitsvo, kukuvara kwemitsipa uye matambudziko eziso. Kutora mishonga (s), kugadzirisa mararamiro (semuenzaniso, kudya, kurovedza muviri, kurega kusvuta), uye kugara uchiongorora shuga yako yeropa kunogona kubatsira kubata chirwere cheshuga uye kugadzirisa hutano hwako. Iyi kurapa inogona zvakare kudzikisira mikana yako yekuve nekurwadziwa kwemoyo, sitiroko, kana zvimwe zvinetso zvine chekuita neshuga senge itsvo kutadza, kukuvara kwemitsipa (chiveve, kutonhora makumbo kana tsoka; kudzikira kugona bonde kune varume nevakadzi), matambudziko eziso, kusanganisira shanduko. kana kurasikirwa kwemaonero, kana chingamu chirwere. Chiremba wako nevamwe vanopa hutano vachataura newe nezvenzira yakanakisa yekurapa chirwere cheshuga.

Kanagliflozin inouya sehwendefa kutora nemuromo. Inowanzo kutorwa kamwe chete pazuva usati wadya mangwanani kana kwekutanga kudya kukuru kwezuva. Tora canagliflozin panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora canagliflozin chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Chiremba wako anogona kukutanga iwe pane yakaderera dosi yecanagliflozin uye zvishoma nezvishoma wedzera yako dosi.

Kanagliflozin inodzora mhando 2 chirwere cheshuga asi haichirape. Ramba uchitora canagliflozin kunyangwe iwe uchinzwa zvakanaka. Usarega kutora canagliflozin usina kutaura nachiremba wako.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora canagliflozin,

  • udza chiremba wako uye wemishonga kana iwe uri weergisi (mapundu, mikoko, kuzvimba kwechiso chako, miromo, rurimi, kana huro, kana kunetseka kufema) kune canagliflozin, chero mimwe mishonga, kana chero chinhu chinowanikwa mumapiritsi ecanagliflozin. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemiti yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: angiotensin-inoshandura enzyme (ACE) inhibitors senge benazepril (Lotensin, muLotrel), captopril, enalapril (Vasotec, muVaseretic), fosinopril, lisinopril (muZestoretic), moexipril (Univasc, Uniretic), perindopril (Aceon, muPrestalia), quinapril (Accupril, muAccuretic, muQuinaretic), ramipril (Altace), uye trandolapril (Mavik, muTarka); angiotensin receptor blockers senge azilsartan (Edarbi, muEdbybyclor), candesartan (Atacand, muAtacand HCT), eprosartan (Teveten), irbesartan (Avapro, muAvalide), losartan (Cozaar, muHyzaar), olmesartan (Benicar, muAzor, muBenicar HCT, muTribenzor), telmisartan (Micardis, muMicardis HCT, muTwynsta), uye valsartan (Diovan, muDiovan HCT, muEexforge); digoxin (Lanoxin); diuretics ('mapiritsi emvura'); jekiseni; mimwe mishonga yechirwere cheshuga; phenobarbital; phenytoin (Dilantin, Phenytek); rifampin (Rifadin, Rimactane, muRifamate, muRifater); uye ritonavir (Norvir, muKaletra). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana iwe uri pane dialysis. Chiremba wako anogona kukuudza kuti usatora canagliflozin.
  • udza chiremba wako kana iwe uchigara uchinwa doro kana dzimwe nguva unonwa yakawanda doro munguva pfupi (kudhakwa kunwa), kana uri pane yakaderera sodium kudya. Zvakare, udza chiremba wako kana iwe wakambodimburwa, kana wakambove nechirwere chemwoyo, peripheral vascular chirwere (kudzikira kwemidzi yeropa mutsoka, makumbo, kana maoko zvichikonzeresa kugwinha, kurwadziwa, kana kutonhora mune icho chikamu chemuviri), neuropathy (kukuvara kwemitsipa kunokonzeresa kutsemuka, chiveve, uye kurwadziwa, kazhinji mumawoko ako nemakumbo), maronda etsoka kana maronda, yakaderera BP, chirwere cheweti, kana matambudziko eweti, chirwere chepancreatic kusanganisira pancreatitis (kuzvimba kwerwatata) kana akavhiyiwa pancreas, mbiriso hutachiona munzvimbo yekubereka, osteoporosis (mamiriro ayo mapfupa anoonda uye kupera simba nekutyoka zviri nyore), itsvo kana chirwere chechiropa. Kana iwe uri murume, udza chiremba wako kana usati wadzingiswa. Udza chiremba wako kana iwe uri kudya zvishoma nekuda kwechirwere, kuvhiyiwa, kana shanduko mukudya kwako kana kana iwe usingakwanise kudya kana kunwa zvakajairika nekuda kwekusvotwa, kurutsa, manyoka, kana kana iwe ukava wakasviba kubva mukuva muzuva rakareba .
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Usamwisa mwana paunenge uchitora canagliflozin. Kana iwe ukava nepamuviri uchitora canagliflozin, fonera chiremba wako.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora canagliflozin.
  • doro rinogona kukonzera shanduko muropa shuga. Kumbira chiremba wako nezve kushandiswa kwakachengeteka kwezvinwiwa zvinodhaka paunenge uchitora canagliflozin.
  • iwe unofanirwa kuziva kuti canagliflozin inogona kukonzera dzungu, huremu husina musoro, uye kupera simba paunosimuka nekukurumidza kubva panzvimbo yekunyepa. Kana uine dambudziko iri, fonera chiremba wako. Dambudziko iri rakajairika paunotanga kutora canagliflozin. Kuti udzivise dambudziko iri, simuka pamubhedha zvishoma nezvishoma, uchizorora tsoka dzako pasi kwemaminetsi mashoma usati wasimuka.
  • bvunza chiremba wako zvekuita kana iwe ukarwara, ukava nehutachiona kana fivha, ukawana kushushikana kusingawanzo, kana kukuvara. Aya mamiriro anogona kukanganisa shuga yako yeropa uye huwandu hwecanagliflozin iwe yaungangoda.

Ive neshuwa yekutevera zvese zvekurovedza muviri uye zvekudya zvinokurudzirwa zvakaitwa nachiremba wako kana wezvekudya. Zvakakosha kudya kudya kunovaka muviri uye kurovedza muviri nguva dzose.


Tevedza rairo yechiremba wako nezve kunwa mvura yakakwana zuva rese iwe uchinge uri pamushonga uyu.

Tora dosi rakarasika nekukurumidza kana uchinge warangarira. Zvisinei, kana yava nguva yenguva inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Mushonga uyu unogona kukonzera shanduko muropa rako shuga. Iwe unofanirwa kuziva zviratidzo zveshuga yakadzika uye yakakwira yeropa uye zvekuita kana iwe uine izvi zviratidzo.

Kanagliflozin inogona kukonzeresa mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kuita weti yakawanda, kusanganisira nehusiku
  • kuwedzera nyota
  • kuvimbiswa
  • muromo wakaoma

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe cheizvi zviratidzo, danaidza chiremba wako nekukasira:

  • kazhinji, kukurumidza, kupisa, kana kurwadza weti
  • kuderera muhuwandu weti
  • weti ine makore, tsvuku, pingi, kana shava
  • weti yakasimba inonhuwa
  • pelvic kana rectal kurwadziwa
  • (mune vakadzi) kunhuhwirira kwemukadzi, chena kana yero yenyuchi kubuda (kungave kune bundu kana kutaridzika sekottage chizi), kana kusangana nekutsi kwemukadzi
  • (mune varume) kutsvuka, kuchenesa, kana kuzvimba kwenhengo yemurume; mapundu panhengo yesikarudzi; kusvibiswa kunhuwa kubva peni; kana kurwadziwa paganda rakatenderedza nhengo yemurume
  • kunzwa kuneta, kushaya simba, kana kusagadzikana; pamwe nefivha uye kurwadziwa, hunyoro, kutsvuka, uye kuzvimba kwenhengo dzesikarudzi kana nzvimbo iri pakati pesikarudzi nerekure

Kana iwe ukawana chero yeanotevera zviratidzo, rega kutora canagliflozin uye dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • mapundu
  • mikoko
  • kuvava
  • kunetseka kumedza
  • kuzvimba kwechiso, huro, rurimi, miromo, muromo, kana maziso
  • hoarseness

Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchirapa. Kana zvichikwanisika, tarisa ketoni mumuguta wako kana uine zviratidzo izvi, kunyangwe shuga yako yeropa iri pasi pe250 mg / dL:

  • kusvotwa
  • kurutsa
  • dumbu-nzvimbo kurwadziwa
  • kuneta
  • kunetseka kufema

Iwe unofanirwa kuziva kuti canagliflozin inogona kuwedzera njodzi yekuve negumbo rakadzika (chigunwe, tsoka, kana gumbo) kutemwa. Chiremba wako anokuudza maitiro ekuchengeta makumbo ako netsoka nemazvo kuti ubatsire kudzivirira hutachiona uye zvinetswa zvingatungamira mukubviswa. Tevedza rairo yechiremba zvakanyatsonaka uye danaidza chiremba wako ipapo kana iwe uine chero kurwadziwa, hunyoro, maronda, maronda, kana kuzvimba, inodziya, yakatsvuka nzvimbo mugumbo kana tsoka, fivha kana kutonhora, kana zvimwe zviratidzo nezviratidzo zvehutachiona.

Kanagliflozin inogona kuwedzera mukana wekutsemuka (pfupa rakatyoka), kunyanya mumaoko ekumusoro, mawoko, kana maoko. Taura nachiremba wako nezve njodzi dzekutora mushonga uyu.

Kanagliflozin inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako anozoraira bvunzo bvunzo usati uye panguva yekurapwa kwako necanagliflozin kuti uone kuti itsvo dzako dziri kushanda sei. Mashuga eropa rako anofanirwa kuongororwa nguva nenguva kuti uone mhinduro yako kune canagliflozin. Chiremba wako acharaira mamwe bvunzo bvunzo, kusanganisira glycosylated hemoglobin (HbA1c), kuti utarise mhinduro yako kune canagliflozin. Chiremba wako anokuudzawo maitiro ekutarisa mhinduro yako kumushonga uyu nekuyera huwandu hweshuga yeropa kumba. Tevedza rairo idzi zvakanyatsonaka.

Usati waita chero bvunzo yerabhoritari, udza chiremba wako nevashandi veirabhoritari kuti uri kutora canagliflozin. Nekuda kwemabatiro anoita mushonga uyu, weti yako inogona kuyedza kuita glucose.

Iwe unofanirwa kugara uchipfeka cheshuga chitupa chiziviso kuti uve nechokwadi chekuti unowana kurapwa kwakakodzera mune emergency.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Invokana®
  • Invokamet® (iine Canagliflozin uye Metformin)
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