Riociguat

Zvemukati

• Usati watora riociguat,
• Riociguat inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana icho chiri mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

Usatore riociguat kana iwe uri nepamuviri kana kuronga kuve nepamuviri. Riociguat inogona kukuvadza fetus. Kana iwe uchiita bonde uye uchikwanisa kuve nepamuviri, haufanire kutanga kutora riociguat kudzamara kuongororwa kwepamuviri kwaratidza kuti hauna nhumbu. Iwe unofanirwa kushandisa nzira dzakavimbika dzekudzivirira kuberekwa panguva yekurapa uye kwemwedzi mumwe mushure mekumisa riociguat. Usaite bonde risina dziviriro. Taura nachiremba wako nezvenzira dzekudzivirira kuberekwa dzinoshanda uye dzichakushandira. Fonera chiremba wako nekukasira kana ukasuwa kuenda kumwedzi kana kufunga kuti ungave nepamuviri paunenge uchitora riociguat.

Kana iwe uri mubereki kana muchengeti wemukadzi anga asati asvika pakuyaruka, tarisa mwana wako nguva nenguva kuti aone kana ari kukura chero zviratidzo zvekuyaruka (mazamu mazamu, vhudzi rebvudzi) uye rega chiremba wake azive nezve chero shanduko. Mwana wako anokwanisa kusvika pakuyaruka asati atanga kuenda kumwedzi.

Nekuda kwenjodzi yekuremara kwekuzvara, riociguat inowanikwa chete kuburikidza neyakaganhurirwa chirongwa chekugovera. Chirongwa chinonzi Adempas Risk Evaluation uye Mitigation Strategies (REMS) Chirongwa chakagadzirirwa vese varwere vechikadzi kuti vaone kuti vanoongororwa nhumbu mwedzi wega panguva yekurapwa uye kwemwedzi mumwe mushure mekumisa riociguat. Vakadzi vechikadzi vanogona kuwana riociguat chete kana ivo vakanyoreswa neAdempas REMS Chirongwa. Panguva yekunyora iwe unosarudza yakasarudzika hunyanzvi hwemishonga iyo inotumira yako mishonga kwauri. Kumbira chiremba wako kana iwe uine chero mibvunzo nezvekuti uchawana sei mushonga wako.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Gwaro RezveMishonga) paunotanga kurapwa ne riociguat uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kuti utore Gwaro reMishonga.

Taura nachiremba wako nezve njodzi dzekutora riociguat.

Riociguat inoshandiswa kurapa pulmonary arterial hypertension (PAH; kukwirisa kweropa mumidziyo inotakura ropa kumapapu). Riociguat inoshandiswawo kurapa chisingaperi thromboembolic pulmonary hypertension (CTEPH; kukwirira kweropa mumapapu etsinga kunokonzerwa neropa rinovhara rinotetepa kana kuvhara ropa kuyerera) kune vanhu vakuru vasingakwanise kuvhiyiwa kana kune avo vanorapwa nekuvhiyiwa vanoramba vaine huwandu hwemapapu eropa. kumanikidza mazinga mushure mekuvhiyiwa. Riociguat inogona kuvandudza kugona kwekurovedza muviri muvanhu vane PAH neCTEPH uye inogona kudzikira kuwedzera kwezviratidzo muvanhu vane PAH. Riociguat iri mukirasi yemishonga inonzi inogadziriswa guanylate cyclase (sGC) inosimudzira. Inoshanda nekuzorodza tsinga dzeropa mumapapu kubvumira ropa kuyerera zviri nyore.

Riociguat inouya sehwendefa kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu katatu pazuva. Tora riociguat panguva dzakatenderedza nguva imwechete (ma) zuva rega rega uye isa nzvimbo yako doses anenge maawa matanhatu kusvika masere akaparadzaniswa. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora riociguat chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Kana iwe usingakwanise kumedza iyo piritsi yakazara, unogona kupwanya piritsi uye kusanganisa zvirimo nemvura shoma kana chikafu chakapfava senge applesauce. Medza musanganiswa uchangobva kuusanganisa.

Chiremba wako anogona kukutanga iwe pane yakaderera dosi ye riociguat uye zvishoma nezvishoma wedzera yako dosi, kwete kanopfuura kamwe chete kwevhiki mbiri. Chiremba wako anogona kudzikisa dhizaini yako kana iwe ukava nemhedzisiro.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora riociguat,

• udza chiremba wako uye wemishonga kana iwe uri weergisi kune riociguat, chero mimwe mishonga, kana chero chipi chinosanganiswa mumapiritsi e riociguat. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako kana uri kutora kana uchangobva kutora nitrate senge isosorbide dinitrate (Isordil, muBiDil), isosorbide mononitrate (Monoket), kana nitroglycerin (Nitro-Dur, Nitromist, Nitrostat, Minitran, Rectiv, vamwe) ,; phosphodiesterase inhibitors (PDE-5) senge avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), kana vardenafil (Levitra, Staxyn); kana kana iwe uri kutora dipyridamole (Persantine, muAgrenrenox), kana theophylline (Theo-24, Theochron, Theolair, vamwe). Chiremba wako angangokuudza kuti usatore riociguat kana uri kutora iyi kana yakawanda yemishonga iyi. Usatore riociguat mukati maawa makumi maviri nemana usati watora kana mushure mekutora sildenafil kana mukati maawa makumi maviri nemana zvisati zvaitika kana maawa makumi mana nemasere mushure mekutora tadalafil.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: mamwe maantifungal akadai itraconazole (Onmel, Sporanox) uye ketoconazole (Extina, Nizoral, Xolegel); HIV protease inhibitors inosanganisira ritonavir (Norvir, muKaletra); mimwe mishonga yekubatwa kwakadai se carbamazepine (Epitol, Equetro, Tegretol, vamwe), phenobarbital, uye phenytoin (Dilantin, Phenytek); nemishonga yekukwira kweropa. Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
• kana iwe uri kutora antacids ine aluminium hydroxide kana magnesium hydroxide (Maalox, Mylanta, Tums, vamwe), tora iwo 1 awa pamberi kana 1 awa mushure mekutora riociguat.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya St. John's wort.
• udza chiremba wako kana iwe uine pulmonary hypertension ne idiopathic interstitial pneumonia (PH-IIP; chirwere chemapapu). Chiremba wako anogona kukuudza iwe kuti usatora riociguat.
• udza chiremba wako kana iwe uchiri kusvuta kana kutanga kana kurega kusvuta panguva yekurapa. Uyezve udza chiremba wako kana uchangobva kuita manyoka, kurutsa, kana kudikitira zvakanyanya izvo zvinogona kunge zvakakonzera kupera mvura (kurasikirwa nehuwandu hwakawanda hwemvura yemuviri); chero kubuda ropa kubva mumapapu ako (s); kana iwe wakambove nenzira yekumisa iwe kubva pakukosora ropa; kana iwe uine yakaderera BP, pulmonary veno-occlusive chirwere (kuvhara kwemitsipa mumapapu); kana moyo, itsvo, kana chirwere chechiropa.
• udza chiremba wako kana iwe uchiyamwisa. Usamwisa mwana paunenge uchitora riociguat.
• iwe unofanirwa kuziva kuti riociguat inogona kukonzera dzungu uye huremu musoro. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti uyu mushonga unokubata sei.

Kunze kwekunge chiremba wako akakuudza neimwe nzira, ramba uchidya zvakajairika.

Darika iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Ukasuwa kutora riociguat kweanopfuura mazuva matatu, fonera chiremba wako. Chiremba wako angangoda kutangazve yako mushonga pane yakaderera dosi.

Riociguat inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• musoro
• kuvimbiswa
• chirungurira
• kugumbuka mudumbu
• kusvotwa
• kurutsa
• manyoka
• kuzvimba kwemaoko ako, makumbo, tsoka, uye makumbo

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi kana icho chiri mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

• kukosora pingi, chihwitsi kana ropa
• kufenda
• kurwadziwa pachipfuva
• mweya wekufema

Riociguat inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako. Chiremba wako anozotarisa yako yeropa nguva dzose panguva yekurapa kwako ne riociguat.

Usarega mumwe munhu achitora mushonga wako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Adempas^®