Venetoclax

Zvemukati

• Usati watora venetoclax,
• Venetoclax inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:
• Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukawana chero yeizvi zviratidzo kana izvo zvakanyorwa mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza:

Venetoclax inoshandiswa yoga kana musanganiswa neobinutuzumab (Gazyva) kana rituximab (Rituxan) kurapa mamwe marudzi echirwere cheLymphocytic leukemia (CLL; rudzi rwekenza inotanga mumasero machena eropa) kana mamwe marudzi madiki e-lymphocytic lymphoma (SLL; mhando yekenza inotanga kunyanya mune ma lymph node). Iyo inoshandiswa zvakare musanganiswa pamwe neazacitidine (Vidaza), decitabine (Dacogen), kana cytarabine seyakatanga kurapwa yeacute myeloid leukemia (AML; mhando yekenza inotanga mumasero machena eropa) muvanhu vane makore makumi manomwe neshanu ekuberekwa kana vakura, kana kune vanhu vakuru vane mamiriro ekurapa anovatadzisa kurapwa nemamwe mishonga yekemotherapy. Venetoclax iri mukirasi yemishonga inonzi B-cell lymphoma-2 (BCL-2) inhibitors. Inoshanda nekudzivirira chiito cheimwe puroteni mumuviri inobatsira maseru ekenza kupona. Izvi zvinobatsira kuuraya cancer maseru.

Venetoclax inouya sehwendefa yekutora nemuromo. Inowanzo kutorwa pamwe nekudya nemvura kamwe chete pazuva. Tora venetoclax panguva dzakatenderedza nguva imwechete mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora venetoclax chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.

Medza mapiritsi akazara; usatsemure, kutsenga, kana kuvapwanya.

Kana iwe ukarutsa mushure mekutora venetoclax, usadzokorora muyero. Enderera yako yenguva dzose dosing purogiramu.

Chiremba wako angangotanga iwe pane yakaderera dosi ye venetoclax uye zvishoma nezvishoma kuwedzera yako dosi, kwete kanopfuura kamwe pasvondo kwevhiki dzekutanga mashanu kana iwe uri kurapwa kweCLL kana SLL, uye kamwe pazuva pazuva kwekutanga 3 kana mana mazuva kana iwe uri kurapwa kwe AML.

Chiremba wako angangoda kukanganisa kana kumisa kurapwa kwako kana iwe ukawana mamwe mhedzisiro. Ive neshuwa yekuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako ne venetoclax. Kune mamwe mhedzisiro, chiremba wako anogona kukuudza kuti utange kutora venetoclax pane yakaderera dosi.

Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Medication Guide) paunotanga kurapwa nevenetoclax uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora venetoclax,

• udza chiremba wako uye wemishonga kana iwe uri weergisi kune venetoclax, chero mimwe mishonga, kana chero chinhu chinowanikwa mumapiritsi e venetoclax. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
• udza chiremba wako kana uri kutora clarithromycin, conivaptan (Vaprisol), indinavir (Crixivan), itraconazole (Onmel, Sporanox), ketoconazole, lopinavir (muKaletra), posaconazole (Noxafil), ritonavir (Norvir, muKaletra, Technivie ), kana voriconazole (Vfend). Chiremba wako anogona kukuudza kuti usatore venetoclax kana uri kutora imwe kana yakawanda yemishonga iyi.
• udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini uye zvekuwedzera zvekudya iwe zvauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero eanotevera: amiodarone (Nexterone, Pacerone), bosentan (Tracleer), captopril, carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril), carvedilol (Coreg), ciprofloxacin (Cipro), cyclosporine (Gengraf, Neoral, Sandimmune), digoxin (Lanoxin), diltiazem (Cardizem, Cartia XT, Diltzac, Taztia, Tiazac), dronedarone (Multaq), efavirenz (Sustiva, muAtripla), erythromycin (EES, Eryc, Eryped, Ery-tab, ), etravirine (Intelence), everolimus (Afinitor, Zortress), felodipine, fluconazole (Diflucan), modafinil (Nuvigil, Provigil), nafcillin (Nallpen), phenytoin (Dilantin, Phenytek), quinidine (muNuedextine), , rifampin (Rifadin, Rimactane, muRifamate, Rifater), sirolimus (Rapamune), ticagrelor (Brilinta), verapamil (Calan, Verelan, muTarka), kana warfarin (Coumadin, Jantoven). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kusangana nevenetoclax, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
• udza chiremba wako kuti ndezvipi zvigadzirwa zvemakwenzi zvauri kutora, kunyanya quercetin kana wort St.
• udza chiremba wako kana iwe kana wakambove nematambudziko nemazinga ako e potasium, phosphorus, kana calcium muropa rako; yakakwira uric acid muropa rako; gout (rudzi rweArthritis runokonzerwa nemakristasi akaiswa mumajoini); kana hosha yeitsvo kana yechiropa.
• udza chiremba wako kana iwe uine pamuviri kana kuronga kuva nepamuviri. Kana iwe uchikwanisa kuve nepamuviri, iwe uchafanirwa kuve nemimba yekubata usati watanga kurapwa nevenetoclax. Iwe haufanire kuve nepamuviri panguva yekurapa kwako uye kwemazuva makumi matatu mushure mekuita kwako kwekupedzisira. Taura nachiremba wako nezve nzira dzekudzivirira kuberekwa dzaunogona kushandisa panguva yekurapa kwako. Kana iwe ukava nepamuviri uchitora venetoclax, danaidza chiremba wako.
• udza chiremba wako kana iwe uchiyamwisa. Usamwisa mwana paunenge uchitora venetoclax uye kwevhiki rimwe mushure mekupedzisira kwako.
• iwe unofanirwa kuziva kuti uyu mushonga unogona kudzora kubereka muvarume. Taura nachiremba wako nezve njodzi dzekutora venetoclax.
• hauna majekiseni asati, panguva, kana mushure mekurapwa nevenetoclax pasina kutaura nachiremba wako.
• iwe unofanirwa kuziva kuti iwe unogona kusangana ne tumor lysis syndrome (TLS; mamiriro anokonzereswa nekukurumidza kuparara kwekenza maseru ayo anogona kukonzera itsvo kutadza uye zvimwe zvinetswa) panguva yekurapa kwako ne venetoclax. Izvi zvinowanzoitika kana iwe uchitanga kurapwa, uye nguva imwe neimwe dhosi rako riwedzerwa. Kubatsira kudzikisa njodzi yako yekusangana neTLS iwe unofanirwa kunwa angangoita magirazi matanhatu kusvika masere (makumi mana kusvika makumi matanhatu nemasere) emvura pazuva kwemazuva maviri zvisati zvaitika uye pazuva remushonga wako wekutanga, uye nguva yega yedosi yako painowedzerwa. Pamusoro pezvo chiremba wako anokupa mushonga wekuti utore usati watanga uye panguva yekurapa kwako kubatsira kudzivirira iyi divi mhedzisiro. Kana iwe uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchinge uchiita

Usadye grapefruit, starfruit, kana Seville maorenji (dzimwe nguva anoshandiswa mumarmalade), kana kunwa jisi remuzambiringa paunenge uchitora mushonga uyu.

Kana iwe uchirangarira iro rakarasika dhizaini mukati maawa masere yenguva yawakange wakarongerwa kuitora, tora iyo yakarasika dosi ipapo ipapo. Nekudaro, kana anopfuura maawa masere apfuura kubva panguva yaunowanzo kutora venetoclax, ruka iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Ukasuwa kutora venetoclax kwemazuva anopfuura manomwe, unofanirwa kufonera chiremba wako usati watora chero mumwe mushonga. Chiremba wako angangoda kutangazve yako mushonga pane yakaderera dosi.

Venetoclax inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

• manyoka
• kuvimbiswa
• kusvotwa
• kurutsa
• kuderera kwechido
• kuneta zvakanyanya
• kuzvimba kwemaoko ako kana maoko
• kurwadziwa shure
• pfupa, mhasuru, kana kurwadziwa kwemajoini
• marwadzo emudumbu
• kuzvimba kana maronda mumuromo
• kurwadziwa mumuromo kana pahuro
• musoro
• inoyerera kana isina mhino, kukosora
• mweya wekufema
• dzungu
• mapundu
• kunetseka kurara kana kuramba wakarara

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukawana chero yeizvi zviratidzo kana izvo zvakanyorwa mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza:

• fivha yega kana pamwe nehuro, chikosoro, kutonhora, kudziya, tsvuku, kurwadziwa kana kuzvimba ganda, kukurumidza, kazhinji, kana kurwadza kuita weti, uye zvimwe zviratidzo zvehutachiona.
• kuderera kwekuita weti
• kuzvimba kwemakumbo ako, makumbo, kana tsoka
• kubuda zvisina kujairika kana kunorema kubuda ropa kana kupwanya
• rakachenuruka ganda, kufema kwekufema, dzungu, kuneta zvakanyanya, kukurumidza kurova kwemoyo

Venetoclax inogona kukonzera mimwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Ita kwete chinjana mushonga kune mumwe mudziyo. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari ekuongorora usati uye panguva yekurapa kwako kuti utarise mhinduro yemuviri wako kune venetoclax.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

• Venclexta^®