Munyori: Janice Evans
Zuva Rekusika: 23 Chikunguru 2021
Gadziridza Zuva: 16 Mbudzi 2024
Anonim
New drug, ozanimod, transforms the future for people with MS
Vhidhiyo: New drug, ozanimod, transforms the future for people with MS

Zvemukati

Ozanimod inoshandiswa kurapa vanhu vakuru vane nzira dzekudzokororazve dze multiple sclerosis (MS; chirwere umo tsinga dzisingashande nemazvo uye vanhu vanogona kuona kushaya simba, kupera simba, kurasikirwa kwekubatana kwemhasuru, uye matambudziko nemaonero, kutaura, uye kudzora kwedundira) kusanganisira kiriniki yakasarudzika syndrome (CIS; tsinga yezviratidzo zvikamu zvinogara maawa angangoita makumi maviri nemana), kudzokorodza-kuregedza mafomu (kosi yechirwere uko zviratidzo zvinomuka nguva nenguva), kana mafomu echipiri anofambira mberi (kosi yechirwere uko kudzokazve kunoitika kazhinji). Ozanimod iri mukirasi yemishonga inonzi sphingosine l-phosphate receptor modulators. Inoshanda nekudzora kuita kwema immune maseru anogona kukonzera kukuvara kwetsinga.

Ozanimod inouya sekapuleti kutora nemuromo. Inowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Tora ozanimod kwakatenderedza nguva yakafanana zuva rega rega. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora ozanimod chaizvo sekurairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Kumedza macapsule akazara; usavhure, kutsenga, kana kuapwanya.

Chiremba wako angangotanga iwe pane yakaderera dosi yeozanimod uye zvishoma nezvishoma wedzera yako dosi pane yekutanga vhiki

Ozanimod inogona kubatsira kudzora akawanda sclerosis zviratidzo, asi haivarape. Chiremba wako anokucherechedza zvakanyatsoona kuti ozanimod inoshanda sei kwauri. Zvakakosha kuudza chiremba wako kuti uri kunzwa sei panguva yekurapwa kwako.

Chiremba wako kana wemishonga achakupa gwaro reruzivo rwevarwere (reMedicine Gwara) paunotanga kurapwa neozanimod uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa; bvunza chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora ozanimod,

  • udza chiremba wako uye wemishonga kana uri weergoria kune ozanimod, chero mimwe mishonga, kana chero chinhu chinowanikwa muozanimod capsules. Kumbira wemishonga wako kana tarisa Gwaro Rekurapa kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana uri kutora MAO inhibitor yakadai isocarboxazid (Marplan), linezolid (Zyvox), methylene bhuruu, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), kana tranylcypromine (Parnate) kana kuti warega kutora imwe mishonga iyi mukati memasvondo maviri apfuura. Chiremba wako angangokuudza kuti haufanire kutora ozanimod panguva ino. Kana iwe ukarega kutora ozanimod, iwe unofanirwa kumirira mazuva gumi nemana usati watanga kutora MAO inhibitor.
  • udza chiremba wako uye wemishonga kuti ndeipi imwe mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvinowedzera zvinovaka muviri, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero yeanotevera: clopidogrel (Plavix); cyclosporine (Gengraf, Neoral, Sandimmune); eltrombopag (Promacta); erythromycin (EES, Erythromycin, vamwe); gemfibrozil (Lopid); mishonga yekurova kwemoyo zvisina kujairika senge amiodarone (Nexterone, Pacerone), procainamide, uye quinidine (muNuedexta); opioid (narcotic) mishonga inorwadza yakadai se meperidine (Demerol), methadone (Dolophine, Methadose), uye tramadol; rifampin (Rifadin, Rimactane, muRifamate, vamwe); serotonin-reuptake inhibitors senge citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, muSymbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), uye sertraline (Zoloft); uye serotonin uye norepinephrine reuptake inhibitors senge desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), milnacipran (Savella), uye venlafaxine (Effexor); uye sotalol (Betapace, Sorine, Sotylize). Uyezve udza chiremba wako kana iwe uri kutora chero eanotevera mishonga, kana kana iwe wakanwa iwo munguva pfupi yapfuura: alemtuzumab (Campath, Lemtrada); corticosteroids senge dexamethasone, methylprednisolone (Medrol), uye prednisone (Rayos); mishonga yekenza; uye mishonga yekunetesa kana kudzora immune system yakadai se glatiramer (Copaxone, Glatopa) uye interferon beta (Betaseron, Extavia, Plegridy). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro. Mimwe mishonga yakawanda inogona zvakare kubatana neozanimod, saka ive shuwa kuudza chiremba wako nezve yese mishonga yauri kutora, kunyangwe iyo isinga oneke pane ino runyorwa.
  • udza chiremba wako kana iwe wakarwara nemoyo, kurwadziwa pachipfuva, kurohwa kana mini-stroke, kana kukundikana kwemoyo mumwedzi mitanhatu yekupedzisira. Uyezve, udza chiremba wako kana iwe uine kusagadzikana kwemoyo kusinga gadziriswe nepacemaker, kana kana uine hope dzekufema (kumisa kufema kwenguva pfupi panguva yekurara). Chiremba wako angangokuudza kuti usatore ozanimod.
  • udza chiremba wako kana iwe uine fever, huro, kukosora, kutonhora, kuzvimba gland, kana zvimwe zviratidzo zvehutachiona, kana uine hutachiona hunouya nekuenda kana husingaendi, kana kana iwe usingakwanise kurwisa hutachiona. nekuda kwechimwe chirwere. Zvakare, udza chiremba wako kana iwe wakambove uine yakakwira BP, inononoka kurova kwemoyo, chirwere cheshuga, uveitis (kuzvimba kweziso) kana mamwe matambudziko eziso, kana chirwere chemoyo kana chechiropa.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Iwe unofanirwa kushandisa zvinobudirira kuberekwa panguva yekurapa kwako neozanimod uye kwemwedzi mitatu mushure medosi yako yekupedzisira. Kana iwe ukava nepamuviri uchitora ozanimod, dana chiremba wako nekukurumidza.
  • udza chiremba wako kana iwe wakabayiwa nhomba mumazuva makumi matatu apfuura usati watanga kurapwa kwako neozanimod. Hauna chero majekiseni panguva yekurapa kwako kana kwemwedzi mitatu mushure mekupedzisira dosi yako usingataure nachiremba wako.
  • udza chiremba wako kana usati wambobatwa nehuku uye usati wagamuchira mushonga wehuku (varicella). Chiremba wako anogona kuraira kuongororwa kweropa kuti aone kana iwe wakambosangana nehuku huku. Iwe ungangoda kugamuchira mushonga wehukupukisi uye wozomirira mwedzi mumwe usati watanga kurapwa kwako neozanimod.
  • iwe unofanirwa kuziva kuti ozanimod inogona kukonzera dzungu, huremu husina musoro, uye kupera simba paunosimuka nekukurumidza kubva panzvimbo yekunyepa. Izvi zvinowanzoitika kana iwe ukatanga kutora ozanimod. Kuti udzivise dambudziko iri, simuka pamubhedha zvishoma nezvishoma, uchizorora tsoka dzako pasi kwemaminetsi mashoma usati wasimuka.

Unogona kusangana nekuita kwakakomba kana iwe ukadya chikafu chakakwirira mu tyramine panguva yekurapa kwako neozanimod. Tyramine inowanikwa mune zvakawanda zvekudya uye zvinwiwa, zvinosanganisira nyama, huku, hove, kana chizi izvo zvakaputa, zvakakwegura, zvisina kuchengetedzwa zvisina kukodzera, kana kushatiswa; mimwe michero, miriwo, uye bhinzi; zvinwiwa zvinodhaka; uye mbiriso zvigadzirwa zvakavira. Chiremba wako kana chiremba wezvekudya achakuudza kuti ndezvipi zvekudya zvaunofanira kudzivirira zvachose, uye ndezvipi zvekudya zvaunogona kudya zvishoma. Kana iwe uchidya chikafu chakakwirira mu tyramine paunenge uchitora ozanimod, bata chiremba wako.


Kana iwe ukarasikirwa imwe kana yakawanda doses mukati memazuva gumi ekutanga ekurapwa, taura nachiremba wako usati watanga kuitora zvakare. Iwe unozofanirwa kutangazve iyo mishonga pane yakaderera dosi uye zvishoma nezvishoma kuwedzera iyo dosi.

Kana iwe ukarasikirwa nedosi mushure memazuva gumi nemana ekutanga ekurapwa, enderera yako yenguva dzose dosing purogiramu zuva rinotevera. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Ozanimod inogona kukonzera mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • kurwadziwa shure

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo izvi, rega kutora ozanimod uye fonera chiremba wako nekukurumidza kana kuwana kurapwa kwekukurumidzira:

  • fivha, kukosora, kurwadziwa pahuro, kumhanyisa mhino, kana kunorwadza uye kazhinji kuita weti panguva yekurapa uye kusvika kumwedzi mitatu mushure mekupedzisira kwako
  • kutemwa nemusoro, kuomarara kwemutsipa, kupisa muviri, kunzwisisika kuchiedza, kuda kurutsa, kana kuvhiringidzika panguva yekurapwa uye kusvika pamwedzi mitatu mushure mekuita kwako kwekupedzisira
  • kusvotwa, kurutsa, kurasikirwa nehavi, kurwadziwa mudumbu, kuita yero kweganda kana maziso, kana weti yakasviba
  • kusvibiswa, mimvuri, kana bofu nzvimbo pakati pechiratidzo chako; kunzwisisika kuchiedza; isina kujairika ruvara kune chiono chako kana mamwe matambudziko ekuona
  • kamwe kamwe kwakakomba musoro, kuvhiringidzika, shanduko muchiono, kana kubatwa
  • kushaya simba kune rumwe rutivi rwemuviri kana kusindimara kwemaoko kana makumbo izvo zvinowedzera kuwedzera nekufamba kwenguva; shanduko mukufunga kwako, ndangariro, kana kuenzanisa; kuvhiringidzika kana kuchinja hunhu; kana kupera simba
  • mapundu; mikoko; kana kuzvimba kwemiromo, kumeso, kana rurimi
  • nyowani kana kuwedzera kupfupika kwekufema
  • dzungu, kuneta, kurwadziwa pachipfuva, kana kunonoka kana kusagadzikana kwemwoyo

Ozanimod inogona kuwedzera njodzi yekuva nekenza yeganda. Taura nachiremba wako nezve njodzi dzekutora mushonga uyu.


Iko kamwe kamwe kuwedzera kwezvikamu zveMS zviratidzo uye kuwedzera kwekuremara kunogona kuitika mushure mekumira kutora ozanimod. Udza chiremba wako kana zviratidzo zvako zveMS zvichiwedzera mushure mekumira kutora ozanimod.

Ozanimod inogona kukonzera mamwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Zvichengetedze pane tembiricha yemukati uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi).

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe uye kusvika kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakavharira makapu ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye kubva kwavari uye kusvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Panzvimbo iyoyo, nzira yakanakisa yekurasa mishonga yako ndeyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Iwe unozogashira iyo electrocardiogram (ECG; bvunzo iyo inorekodha mashandiro emagetsi emoyo) usati watora yako yekutanga dosi. Chiremba wako anozorairawo kumwe kuongorora kwebazi, bvunzo dzemaziso, uye anozotarisa kuwedzerwa kweropa rako usati uye panguva yekurapwa kwako kuve nechokwadi kuti zvakachengeteka kuti iwe utange kutora kana kuramba uchitora ozanimod.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

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