Munyori: Gregory Harris
Zuva Rekusika: 13 Kubvumbi 2021
Gadziridza Zuva: 17 Mbudzi 2024
Anonim
Topiramate - Mechanism, precautions, side effects & uses
Vhidhiyo: Topiramate - Mechanism, precautions, side effects & uses

Zvemukati

Topiramate inoshandiswa yoga kana iine mimwe mishonga yekurapa mamwe marudzi ekubatwa anosanganisira epasi rose tonic-clonic seizures (yaimbozivikanwa sekubatwa kwakakura kwemal; kubatwa uko kunosanganisira muviri wese) uye kusarura kwekutanga kubatwa (kubatwa kunosanganisira chikamu chimwe chete che uropi). Topiramate inoshandiswa zvakare nemimwe mishonga yekudzora kubatwa muvanhu vane Lennox-Gastaut syndrome (chirwere chinokonzeresa uye kusimudzira kunonoka). Topiramate inoshandiswa zvakare kudzivirira migraine misoro asi kwete kubvisa marwadzo emusoro wemusoro kana achinge aitika. Topiramate iri mukirasi yemishonga inonzi anticonvulsants. Inoshanda nekuderedza kusakwana kusinganzwisisike muuropi.

Topiramate inouya sehwendefa, rinosasa capsule (kapsule iyo ine zvidiki zvidiki zvemushonga zvinogona kumwayiwa pachikafu), uye yakawedzerwa-kuburitsa (refu-inoshanda) capsule yekutora nemuromo. Mahwendefa uye anosasa macapsule anowanzo kutorwa pamwe kana pasina chikafu kamwe kana kaviri pazuva. Iwo akawedzerwa-kuburitswa makapuru anowanzo kutorwa pamwe kana pasina chikafu kamwe pazuva. Tora topiramate panenge panguva imwechete (ma) mazuva ese. Tevedza zvinongedzo pane yako tsamba yekunyora zvakanyatsonaka, uye bvunza chiremba wako kana wemishonga kuti atsanangure chero chikamu chausinganzwisise. Tora topiramate chaizvo sezvakarairwa. Usatore zvimwe kana zvishoma nezvayo kana kuitora kakawanda pane zvakatemwa nachiremba wako.


Kune mumwe mushonga une zita rakafanana nezita rechiratidzo che topiramate. Iwe unofanirwa kuve neshuwa kuti iwe unogashira topiramate uye kwete yakafanana mishonga nguva dzese paunozadza mushonga wako. Iva nechokwadi chekuti mushonga waunopihwa nachiremba wakajeka uye uri nyore kuverenga. Taura nachiremba wako kuti uve nechokwadi chekuti iwe unopihwa topiramate. Kana iwe uchifunga kuti wakapihwa isiriyo mishonga, taura nachiremba wako. Usatore chero mushonga kunze kwekunge uine chokwadi kuti ndiwo mushonga wakarairwa nachiremba wako.

Mahwendefa eTopiramate ane kuravira kunorwadza saka unofanirwa kumedza iwo akazara. Izvo zvinonyanya kukosha kuti usatore matopiramate mahwendefa akaputswa kwehurefu hwenguva nekuti mahwendefa akaputswa anogona kurasikirwa nekushanda kwawo nekufamba kwenguva.

Iyo inosasa uye yakawedzerwa-kuburitsa makapuru (Qudexy XR brand chete) inogona kumedzwa izere kana kuvhurwa uye kudururwa pamusoro pezvinyoro chikafu. Kumedza akawedzera-kuburitsa makapuleti (Trokendi XR brand chete) yakazara; usatsemure, kutsenga, kana kumwaya chikafu.


Kuti utore macapsule ekusasa kana akawedzera-kuburitsa makapisi (Qudexy XR brand chete) nechikafu, tevera nhanho idzi:

  1. Gadzirira teaspoonful yezvokudya zvakapfava senge applesauce, custard, ice cream, oatmeal, pudding, kana yogati.
  2. Bata capsule yakatwasuka pamusoro pechikafu.
  3. Bvisa kubva pamusoro pekapisi uye udururire zvese zvirimo mupunu yechikafu.
  4. Medza musanganiswa wese nekukasira pasina kutsenga.
  5. Inwa zvinwiwa uchangobva kumedza kugeza musanganiswa uye kuve nechokwadi kuti unomedza yese.

Chiremba wako angangotanga iwe pane yakaderera dosi yetopiramate uye zvishoma nezvishoma wedzera yako dosi, kwete kupfuura kamwe chete pasvondo.

Topiramate inogona kudzora kubatwa kwako kana migraines asi isingarape mamiriro ako. Ramba uchitora topiramate kunyangwe iwe uchinzwa zvakanaka. Usarega kutora topiramate usingataure nachiremba wako, kunyangwe iwe ukave nemhedzisiro senge shanduko isina kujairika mumaitiro kana manzwiro. Kana iwe ukangoerekana warega kutora topiramate, iwe unogona kuve nekugumbuka kwakanyanya, kunyangwe kana usati wambobatwa nepfungwa munguva yakapfuura. Chiremba wako angangoderedza dhizaini yako zvishoma nezvishoma.


Chiremba wako kana wemishonga anokupa iro gadziriro yeruzivo yemurwere (Mishonga Inotungamira) paunotanga kurapwa ne topiramate uye pese paunozadza mushonga wako. Verenga iwo ruzivo nokungwarira uye bvunza chiremba wako kana wemishonga kana iwe uine chero mibvunzo. Iwe unogona zvakare kushanyira Chikafu neDrug Administration (FDA) webhusaiti (http://www.fda.gov/Drugs) kana webhusaiti yemugadziri kuti utore Gwaro reMishonga.

Topiramate inoshandiswa zvakare kune manejimendi kudhakwa kudhakwa. Taura nachiremba wako nezve njodzi dzekushandisa mushonga uyu kune ako mamiriro.

Mushonga uyu unogona kupihwa zvimwe zvinoshandiswa. Kumbira chiremba wako kana wemishonga kuti uwane rumwe ruzivo.

Usati watora topiramate,

  • udza chiremba wako uye wemishonga kana iwe uri weergisi kune topiramate, chero mimwe mishonga, kana chero chinhu chinogadzirwa mumapiritsi etopiramate, kusasa macapsule, uye akawedzera-kuburitsa makapisi. Kumbira wako wemishonga kuti uwane runyorwa rwezvigadzirwa.
  • udza chiremba wako kana uine metabolic acidosis (kukanganiswa mumuviri acid-base bhalansi iyo inoguma neyakawandisa acidity yeropa) uye iwe uri kutora metformin (Fortamet, Glucophage, Riomet, vamwe). Chiremba wako angangokuudza kuti usatore metformin kana uine metabolic acidosis uye uri kutora izvi zvemishonga.
  • udza chiremba wako uye wemishonga kuti ndeipi mishonga yekunyorera uye isina kunyoreswa, mavitamini, zvekuwedzera pane zvekudya, uye mishonga yemakwenzi yauri kutora kana kuronga kutora. Ive neshuwa yekutaura chero yeanotevera: acetazolamide (Diamox); amitriptyline; anticoagulants ('blood thinner') senge warfarin (Coumadin); mishonga inodzvinyirira; antihistamines; asipurini uye mamwe asiri -steroidal anti-anogumbura mishonga (NSAIDs) senge ibuprofen (Advil, Motrin) uye naproxen (Aleve, Naprosyn); digoxin (Lanoxin); mishonga yekudzivirira mhuri (mapiritsi ekudzivirira kubereka, zvigamba, mhete, mapiritsi, kana majekiseni); hydrochlorothiazide (Microzide, Oretic); lamotrigine (Lamictal); lithium (Lithobid); mishonga yekurwara kwekufamba, maronda, kana matambudziko eweti; metformin (Fortamet, Glucophage, Riomet, nevamwe); mimwe mishonga yekubatwa senge carbamazepine (Epitol, Equetro, Tegretol, Teril), phenytoin (Dilantin, Phenytek), valproic acid (Depakene), uye zonisamide (Zonegran); uye pioglitazone (Actos, muActoplus Met ER). Chiremba wako angangoda kushandura madosi emishonga yako kana kukutarisisa nokungwarira mhedzisiro.
  • udza chiremba wako kana iwe kana chero nhengo yemhuri wakambove kana wakambove nematombo eitsvo, uye kana iwe wakambofunga nezvekuzviuraya iwe kana kuyedza kuzviita. Uyezve udza chiremba wako kana iwe wakambove kana metabolic acidosis (kukanganiswa mumuviri weasidhi-base bhalosi inoguma yakawandisa acidity yeropa); osteopenia, osteomalacia, kana osteoporosis (mamiriro umo mapfupa akapfava kana kupwanyika uye anogona kutyora nyore); chirwere cheshuga; glaucoma (rudzi rwechirwere chemaziso); chero chirwere chinokanganisa kufema kwako senge asthma kana chisingaperi obstructive pulmonary chirwere (COPD); kushushikana kana kusanzwisisika mamoods; dambudziko rekukura; kana chiropa kana chirwere cheitsvo. Uyezve udza chiremba wako kana iwe uine manyoka kana kana iwe uchikura manyoka panguva yekurapwa kwako.
  • udza chiremba wako kana iwe uri nepamuviri, ronga kuve nepamuviri, kana uri kuyamwisa. Kana iwe uri nepamuviri kana kuronga kuve nepamuviri, chiremba wako anogona kupa mushonga wakasiyana pane topiramate nekuti topiramate inogona kukuvadza fetus. Kana iwe usiri kuronga kuve nepamuviri, iwe unofanirwa kushandisa kuberekwa kudzivirira kudzivirira kubata panguva yekurapa kwako netopiramate. Taura nachiremba wako nezverudzii rwerubatsiro rwaunofanira kushandisa, nekuti kutora topiramate kunogona kudzikisira kushanda kwemamwe marudzi ekudzivirira kuberekwa. Kana iwe ukava nepamuviri iwe uri kutora topiramate, dana chiremba wako ipapo, asi usamire kutora topiramate usati wataura nachiremba wako.
  • kana uri kuvhiyiwa, kusanganisira kuvhiya mazino, udza chiremba kana chiremba wemazino kuti urikutora topiramate.
  • iwe unofanirwa kuziva kuti topiramate inogona kukuita iwe kukotsira, kutenderera, kuvhiringidzika, kana kutadza kuisa pfungwa. Usatyaire mota kana kushandisa michina kusvikira iwe waziva kuti uyu mushonga unokubata sei.
  • kana iwe uri kutora topiramate kudzora kubatwa, iwe unofanirwa kuziva kuti iwe unogona kuramba uchinge uchinge uchinge uchinge uchinge uchirapwa. Iwe ungangoda kudzivirira zviitwa zvakaita sekushambira, kutyaira, uye kukwira kuitira kuti urege kuzvikuvadza kana vamwe kana ukarasikirwa nehana panguva yekubata.
  • udza chiremba wako kana iwe ukanwa doro. Iwe haufanire kunwa doro mukati maawa matanhatu zvisati zvaitika uye maawa matanhatu mushure mekutora akawedzera-kuburitsa makapisi (Trokendi XR brand chete). Chiremba wako angangokuudza kuti usanwa doro uchitora topiramate.
  • iwe unofanirwa kuziva kuti topiramate inogona kukudzivirira kubva kudikitira uye kuita kuti zviomere muviri wako kutonhorera kana kuchipisa zvakanyanya. Izvi zvinowanzoitika kazhinji mumamiriro ekunze anodziya uye kuvana vanotora topiramate. Dzivisa kusangana nekupisa, inwa mvura yakawanda uye udza chiremba wako kana uine fivhiri, musoro, kushushikana kwemhasuru, kana mudumbu wakatsamwa, kana kana usiri kudikitira senguva dzose.
  • iwe unofanirwa kuziva kuti iwe unogona kuve unokwanisa kuita dombo reitsvo paunenge uchitora topiramate. Inwa magirazi emvura matanhatu kusvika kumasere zuva rega rega kudzivirira mabwe eitsvo kubva pakuumbwa.
  • iwe unofanirwa kuziva kuti hutano hwako hwepfungwa hunogona kuchinja nenzira dzisingatarisirwi uye unogona kuzviuraya (kufunga nezvekuzvikuvadza kana kuzviuraya kana kuronga kana kuyedza kuzviita) paunenge uchitora topiramate yekurapa pfari, kurwara nepfungwa, kana mamwe mamiriro. Chiverengero chidiki chevakuru uye vana vane makore mashanu ekuberekwa uye kupfuura (vangangoita 1 muvanhu mazana mashanu) vakatora anticonvulsants senge topiramate kurapa akasiyana mamiriro panguva yekiriniki yekudzidzira kuzviuraya panguva yekurapwa kwavo. Vamwe vevanhu ava vakaita pfungwa dzekuzviuraya uye hunhu sekutanga svondo rimwe mushure mekutanga kwavo kutora mishonga. Pane njodzi yekuti unogona kusangana neshanduko yehutano hwepfungwa kana ukatora mishonga inorwisa antivivulsant senge topiramate, asi panogona zvakare kuve nenjodzi yekuti iwe uchaona shanduko muhutano hwako hwepfungwa kana mamiriro ako asina kurapwa. Iwe nachiremba wako muchasarudza kana njodzi dzekutora mushonga weanticonvulsant dzakakura kudarika njodzi dzekusatora mushonga. Iwe, mhuri yako, kana mutarisiri wako unofanirwa kufonera chiremba wako ipapo kana iwe ukawana chero cheanotevera zviratidzo: kuvhunduka kwekutya; kusagadzikana kana kusagadzikana; kutsva kana kuwedzera kutsamwa, kushushikana, kana kushushikana; kuita zvishuvo zvine ngozi; kunetseka kudonha kana kuramba wakarara; hasha, hasha, kana kuita zvechisimba; mania (kupenga, kusanzwisisika zvisingaite); kutaura kana kufunga nezvekuda kuzvikuvadza kana kupedza hupenyu hwako; kurega shamwari nemhuri; kubatikana nerufu nekufa; kupa zvinhu zvinokosha; kana chero imwe shanduko isina kujairika mumaitiro kana manzwiro. Iva nechokwadi chekuti mhuri yako kana muchengeti anoziva kuti ndezvipi zviratidzo zvingave zvakakomba saka vanogona kufonera chiremba kana iwe usingakwanise kutsvaga kurapwa iwe wega.

Taura nachiremba wako nezvekuwedzera huwandu hwechikafu chaunodya kana ukarasa huremu paunenge uchitora topiramate.

Taura nachiremba wako usati wachinja chikafu chako kana kutanga chero mhando yehuremu chirongwa. Usateedzere chikafu cheketogenic (chakakora-mafuta, chakaderera-makabhohydrate chikafu chinoshandiswa kudzora kubatwa) kana chero imwe yakakwira-mafuta, yakaderera-macarhydrate chikafu, senge iyo Atkins chikafu, iwe uchiri kutora mushonga uyu.

Kana iwe uri kutora topiramate mahwendefa kana kumwaya macapsule, tora iyo yakarasika dhizai nekukurumidza kana uchinge uchayeuka izvozvo. Nekudaro, kana iri isingasviki maawa matanhatu usati warongerwa kutora yako inotevera dosi, ruka iro rakarasika dosi uye enderera yako yenguva dzose dosing purogiramu. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika.

Kana iwe uri kutora topiramate yakawedzera-kuburitswa makapisi, tora iyo yakarasika dhizai nekukurumidza kana uchinge uchayeuka izvozvo. Zvisinei, kana yava nguva yenguva yako inotevera, svetuka chirwere chakarasika uye ramba uchiita purogiramu yako yenguva dzose. Usatore dosi yakapetwa kaviri kuti uwane imwe yakarasika. Kana iwe uchinge warasikirwa neinopfuura imwe dose, bata chiremba wako.

Topiramate inogona kukonzera mimwe mhedzisiro. Udza chiremba wako kana chimwe chezviratidzo izvi chakanyanya kana kuti chisingaendi:

  • chiveve, kupisa, kana kugwinha maoko kana tsoka
  • kudzora kuita
  • huta
  • musoro
  • kutsimwaira
  • kushaya simba
  • kuzunza kusingadzoreki nhengo yemuviri
  • kufamba kusingadzoreki kwemaziso
  • kuonda
  • kuvimbiswa
  • chirungurira
  • chinja mukugona kuravira chikafu
  • muromo wakaoma
  • mumhino
  • misodzi kana kuoma maziso
  • musana, mhasuru, gumbo, kana kurwadziwa kwepfupa
  • kusuwa kumwedzi
  • kubuda ropa zvakanyanya kumwedzi
  • kubuda ropa zvisina kujairika kana kupwanya

Mimwe mhedzisiro inogona kuve yakakomba. Kana iwe ukasangana nechimwe chezviratidzo zvinotevera kana izvo zvakanyorwa mune YAKAKOSHA PRECAUTIONS chikamu, dana chiremba wako nekukurumidza:

  • mapundu, ganda rinobuda, kana ganda rinodonha
  • kusaona zvakanaka
  • kurasikirwa kwemaonero
  • kuona kaviri
  • kurwadziwa kweziso
  • kutsvuka kwemaziso
  • kuwedzera kwekutora
  • kunzwa kutonhora, kutonhora, kana kudzikira kwemuviri tembiricha
  • kunetseka kuisa pfungwa
  • matambudziko ekutaura, kunyanya kunetseka kufunga kwemamwe mazwi
  • kuvhiringidzika
  • matambudziko ekurangarira
  • kurasikirwa kwekubatana
  • kurova kana kusagadzikana kwemoyo zvisina kujairika
  • kurwadziwa pachipfuva
  • mweya wekufema
  • kunetseka kufema
  • kutsanya, kufema kwakadzika
  • kutadza kupindura kuzvinhu zvakakukomberedza
  • kuneta zvakanyanya
  • manyoka
  • kusvotwa
  • kurutsa
  • kurwadziwa nemudumbu
  • kurasikirwa nenzara
  • kurwadziwa kwakanyanya kumashure kana padivi
  • rine ropa, rine makore, kana weti inonhuwa
  • kugara uchida kuita weti
  • kunetseka kuita weti kana kurwadziwa kana uchiita weti
  • fever kana zvimwe zviratidzo zvehutachiona

Topiramate inogona kukonzera osteoporosis (mamiriro umo mapfupa anogona kutyora zviri nyore) muvanhu vakuru uye mariketi (asina kujairika, akakombama mapfupa kukura) muvana. Topiramate inogona zvakare kudzora kukura kwevana uye inogona kudzora kureba kwekupedzisira kunosvika vana. Taura nachiremba wako nezve njodzi dzekutora topiramate.

Topiramate inogona kukonzera mimwe mhedzisiro. Fonera chiremba wako kana uine chero matambudziko asina kujairika uchitora mushonga uyu.

Kana iwe ukawana chakakomba mhedzisiro, iwe kana chiremba wako ungatumira chirevo kuchirongwa cheKudya neDrug Administration's (FDA) MedWatch Yakashata Chiitiko Chirongwa online (http://www.fda.gov/Safety/MedWatch) kana nefoni ( 1-800-332-1088).

Chengetedza iyi mishonga mumudziyo iyo yakauya mukati, yakasungwa yakavharwa, uye isingasvike kune vana. Mahwendefa uye akawedzera-kuburitsa makapuruji anofanirwa kuchengetwa mukamuri tembiricha uye kure nekupisa kwakanyanya uye hunyoro (kwete muchimbuzi). Kumwaya macapsule anofanirwa kuchengetwa pasi kana pazasi pe77 ° F (25 ° C). Usambofa wakachengeta mahwendefa akatsemuka, makapisi, kana musanganiswa wemafuta uye chikafu chisina kunyorova. Izvi zvinofanirwa kushandiswa ipapo ipapo kana kuraswa.

Izvo zvakakosha kuti chengetedza mishonga yese isingaonekwe nekusvikwa kwevana semidziyo yakawanda (senge vhiki nevhiki mapiritsi epfungwa uye ayo emadonhwe eziso, makirimu, zvigamba, uye inhalers) hazvirambe vana uye vana vadiki vanogona kuvhura zviri nyore. Kuchengetedza vana vadiki kubva kune chepfu, gara wakakiya makofia ekuchengetedza uye nekukurumidza isa mishonga munzvimbo yakachengeteka - imwe iri kumusoro uye kure uye isingaonekwe nevanosvika. http://www.upandaway.org

Mishonga isingadiwe inofanirwa kuraswa nenzira dzakakosha kuona kuti zvipfuyo, vana, nevamwe vanhu havagone kuzvidya. Nekudaro, iwe haufanire kuburitsa uyu mushonga pasi pechimbuzi. Pane kudaro, nzira yakanakisa yekurasa yako mishonga ndeye kuburikidza neyekurapa-kudzosa chirongwa. Taura nachiremba wako kana kuti taura nedhipatimendi rako remarara / rekudzokorora kuti udzidze nezve zvirongwa zvekudzosa munharaunda yako. Ona iyo FDA's Safe Disposal yeMedicine webhusaiti (http://goo.gl/c4Rm4p) kuti uwane rumwe ruzivo kana iwe usina mukana wekutora-kudzoka chirongwa.

Kana zvikaitika zvekudarika, fonera iyo chepfu yekudzora rubatsiro pa1-800-222-1222. Ruzivo rwunowanikwawo online pa https://www.poisonhelp.org/help. Kana munhu akabatwa akadonha, akabatwa nepfari, achinetseka kufema, kana kutadza kumutswa, pakarepo danaidza mabasa ekukurumidzira pa911.

Zviratidzo zvekuwedzeredza zvinogona kusanganisira zvinotevera:

  • pfari
  • kutsimwaira
  • matambudziko ekutaura
  • kusaona zvakanaka
  • kuona kaviri
  • kunetseka kufunga
  • kuneta
  • kurasikirwa kwekubatana
  • kurasikirwa kwekuziva
  • dzungu
  • kurwadziwa nemudumbu
  • kurutsa
  • kusagadzikana
  • kuora mwoyo
  • kurasikirwa nenzara
  • kurova kana kusagadzikana kwemoyo zvisina kujairika
  • kutsanya, kufema kwakadzika

Chengetedza zvese zvakagadzwa nachiremba wako uye murabhoritari. Chiremba wako acharaira mamwe marabhoritari bvunzo kuti aongorore mhinduro yemuviri wako kune topiramate.

Usarega mumwe munhu achitora mushonga wako. Kumbira wemishonga wako chero mibvunzo yauinayo nezvekuzadza tsamba yako.

Izvo zvakakosha kuti iwe uchengete yakanyorwa rondedzero yeese emushonga uye asiri ekunyora (pamusoro-e-pikisheni) mishonga yauri kutora, pamwe nezvimwe zvigadzirwa zvakaita sevhitamini, zvicherwa, kana zvimwe zvekuwedzera zvekudya. Iwe unofanirwa kuuya nerondedzero iyi iwe nguva imwe neimwe paunoshanyira chiremba kana kana iwe uchigamuchirwa kuchipatara. Izvo zvakare zvakakosha ruzivo kutakura newe kana zvikaitika zvechimbi-chimbi.

  • Qudexy XR®
  • Topamax®
  • Trokendi XR®
Yekupedzisira Yakagadziridzwa - 08/15/2020

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