Anticholinergics

Zvemukati

• Chinyorwa cheanticholinergics
• Maanticholinergics anoshanda sei
• Zvishandiso
• Yambiro
• Kupisa kupisa uye kupisa kupisa
• Ovhadhozi uye doro
• Zvinopesana mamiriro
• Zvimwe zvinokanganisa
• Taura nachiremba wako
• Chinokosha

Nezve anticholinergics

Anticholinergics imishonga inovhara kuita kwe. Acetylcholine inonzi neurotransmitter, kana kemikari messenger. Inoendesa zviratidzo pakati pemamwe maseru kukanganisa mashandiro emuviri wako.

Anticholinergics inogona kubata akasiyana mamiriro, kusanganisira:

• weti kusagadzikana
• chinodzvinyirira dundira (OAB)
• chisingaperi obstructive pulmonary disorder (COPD)
• mamwe marudzi ehupfu

Ivo zvakare vanobatsira kuvhara kusazvipira kwemhasuru kufamba kwakabatana nezvimwe zvirwere zvakaita sehosha yaPasinson. Dzimwe nguva, anoshandiswa asati avhiyiwa kubatsira kuchengetedza mashandiro emuviri apo munhu anorapwa neanesthesia.

Verenga pamusoro pa:

• rondedzero yemishonga anticholinergic
• ruzivo nezve mashandiro avo
• izvo zvaunofanira kuziva nezve njodzi yavo uye mhedzisiro

Chinyorwa cheanticholinergics

Anticholinergics inongowanikwa chete nachiremba wechiremba. Mienzaniso yemishonga iyi inosanganisira:

• atropine (Atropen)
• belladonna alkaloids
• benztropine mesylate (Cogentin)
• clidinium
• cyclopentolate (Cyclogyl)
• darifenacin (Enablex)
• dicylomine
• fesoterodine (Toviaz)
• flavoxate (Urispas)
• glycopyrrolate
• homatropine hydrobromide
• hyoscyamine (Levsinex)
• ipratropium (Atrovent)
• orphenadrine
• oxybutynin (Ditropan XL)
• propantheline (Pro-banthine)
• scopolamine
• methscopolamine
• solifenacin (VESIcare)
• tiotropium (Spiriva)
• tolterodine (Detrol)
• zvidzx
• trospium

Kunyangwe yakarongedzwa se antihistamine kutorwa kune allergies uye seyokurara rubatsiro, diphenhydramine (Benadryl) zvakare ine anticholinergic mhedzisiro.

Imwe yemishonga iyi inoshanda kurapa chaiwo mamiriro. Chiremba wako achasarudza chakanakisa chinodhaka chemamiriro ako.

Mamwe maanticholinergics anotorwa kubva muzvirimwa zvemhuri inouraya nightshade inonzi Solanaceae. Kupisa midzi, madzinde, uye mhodzi dzezvirimwa izvi zvinoburitsa anticholinergics.Kufema kweutsi kwave kuchishandiswa kwemazana emakore kurapa chirwere chinodzivirira mweya.

Maanticholinergics anoshanda sei

Anticholinergics inovhara acetylcholine kubva pakusunga kune ayo anogamuchira pane mamwe maseru etsinga. Ivo vanodzivisa zviito zvinonzi parasympathetic nerve impulses.

Aya mafunga etsinga anokonzeresa kusazvibata kwemhasuru kufamba mune:

• gastrointestinal turakiti
• mapapu
• weti turakiti
• dzimwe nhengo dzemuviri wako

Kufunga kwemitsipa kunobatsira kudzora mabasa akadai se:

• mate
• kugaya
• kuita weti
• mhungu yekudzivirira

Kuvhara zviratidzo zveacetylcholine kunogona kuderera:

• kusazvibata kwemhasuru kufamba
• kugaya
• mhungu yekudzivirira

Ndicho chikonzero mishonga iyi inogona kukonzera mamwe maratidziro, akadai se:

• kuchengetedza weti
• kuva nemuromo wakaoma

Zvishandiso

Anticholinergics inoshandiswa kurapa akasiyana mamiriro. Izvi zvinosanganisira:

• chisingaperi obstructive pulmonary chirwere (COPD)
• kunyanyisa kuita dundira uye kusagadzikana
• gastrointestinal kusagadzikana, senge manyoka
• asima
• dzungu uye kufamba kwechirwere
• chepfu hunokonzerwa nehupfu hwakadai se organophosphates kana muscarine, iyo inogona kuwanikwa mune mimwe mishonga yezvipembenene uye howa hune chepfu
• zviratidzo zvehosha yaParkinson, senge kusanzwisisika kwekusazvibata kwemhasuru kufamba

Anticholinergics inogona zvakare kushandiswa semhasuru inozorodza panguva yekuvhiyiwa kubatsira neanesthesia. Vanobatsira:

• chengetedza kurova kwemoyo kwakajairika
• zorodza munhu
• kuderera mate secretions

Vamwe vanachiremba vanopa anticholinergics yekushandisa-kurebesa kushandiswa kubatsira kudzikisira kudikitira kwakanyanya. Iyo anticholinergics yakashandiswa zvakanyanya pakurapa uku ndeiyi:

• glycopyrrolate kirimu
• oxybutynin mapiritsi emuromo

Yambiro

Sezvinoita mishonga yakawanda, anticholinergics inouya nenyevero dzinoverengeka.

Kupisa kupisa uye kupisa kupisa

Anticholinergics inoderedza kuwanda kwaunoita ziya, izvo zvinogona kukonzeresa kuti tembiricha yemuviri wako isimuke. Paunenge uchitora mumwe wemishonga iyi, chenjera kuti usanyanya kupisa mukati me:

• kurovedza muviri
• mabhati anopisa
• kunze kunopisa

Kuderedza kudikitira kunogona kukuisa panjodzi yekurohwa neshear.

Ovhadhozi uye doro

Kushandisa yakawandisa anticholinergic chinodhaka kunogona kukonzeresa mukusaziva kana kutofa. Izvi zvinogona kuitikawo kana iwe ukatora anticholinergics nedoro. Zviratidzo zvekuwedzeredza zvinosanganisira:

• dzungu
• kukotsira zvakanyanya
• kupindwa nechando
• zvakanyanya kuona zvisipo
• kuvhiringidzika
• kunetseka kufema
• kusagadzikana uye kutaura kwakashata
• kukurumidza kurova kwemoyo
• kutsva uye kudziya kweganda

Kana iwe uchifunga kuti iwe kana mumwe munhu waunoziva atora zvakawandisa zvemushonga uyu, danaidza chiremba wako kana tsvaga kutungamira kubva kuAmerican Association of Poison Control Centres pa1-800-222-1222 kana kuburikidza nechavo online chishandiso.

Kana zviratidzo zvako zvakakomba, danai 911 kana kuenda kune yepedyo emergency kamuri ipapo.

Zvinopesana mamiriro

Anticholinergics inogona kushandiswa kurapa akawanda mamiriro, asi haasi evose. Semuenzaniso, iyi mishonga haiwanzo kunyorerwa vanhu vakuru.

Anticholinergics inozivikanwa yekukonzera kuvhiringidzika, kurasikirwa ndangariro, uye kuwedzera kushanda kwepfungwa kune vanhu vakura kupfuura makore makumi matanhatu nemashanu. Muchokwadi, izvozvi zvakabatanidza kushandiswa kweanticholinergics ine njodzi yakawandisa yekuora mwoyo.

Zvakare, vanhu vane zvinotevera mamiriro havafanirwe kushandisa anticholinergics:

• myasthenia gravis
• hyperthyroidism
• glaucoma
• yakawedzera prostate
• neBP (yakakwira BP)
• weti turakiti kuvharika
• kuwedzera kwemoyo (tachycardia)
• kutadza kwemoyo
• muromo wakaoma
• hiatal hernia
• kuvimbiswa kwakanyanya
• chirwere chechiropa
• Down chirwere

Udza chiremba wako kana iwe uine chero eaya mamiriro. Zvakare, udza chiremba wako kana iwe uine nhoroondo yekurwara neanticholinergics.

IAmerican Geriatrics Society inokurudzira zvine simba kudzivirira kushandiswa kwemishonga yeanticholinergic kune vakuru vakuru. Izvi zvinodaro nekuti vakuru vanogona kuve nemikana yekuwana mhedzisiro isingadiwe kupfuura vechidiki.

Zvimwe zvinokanganisa

Kunyangwe uchishandisa mushonga uyu nemazvo, mhedzisiro inogona kuitika. Izvo zvinogona kuitika mhedzisiro yeanticholinergics zvinoenderana neicho chaicho chinodhaka uye chipimo chemushonga chaunotora.

Migumisiro inogona kusanganisira:

• muromo wakaoma
• kuona kwakadzikama
• kuvimbiswa
• kutsimwaira
• kunyaradza
• kuona zvisipo
• matambudziko ekurangarira
• kunetseka kuita weti
• kuvhiringidzika
• delirium
• kuderera kwekutuka
• kuderera mate

yeanticholinergics, pamwe nekushandiswa kwemishonga iyi mukati, yakave yakabatana nenjodzi yakawedzera yeundangariro. Kana iwe wakatemerwa imwe yemishonga iyi uye uine zvinetsekana nezve njodzi iyi, ita shuwa yekutaura nachiremba wako.

Taura nachiremba wako

Anticholinergics inogona kushandiswa kurapa akasiyana mamiriro. Kana iwe uchifunga kuti imwe yemishonga iyi inogona kukubatsira, taura nachiremba wako.

Chiremba wako anogona kuona kana kurapwa neanticholinergic kungave sarudzo yakanaka kwauri. Ivo vanogona zvakare kupindura chero mibvunzo yauinayo nezve:

• njodzi
• mhedzisiro
• zvaunotarisira pamwe nekurapwa

Chinokosha

Anticholinergic zvinodhaka zvinodzivisa kuita kweiyo neurotransmitter inonzi acetylcholine. Izvi zvinodzvinyirira tsinga dzinokonzeresa nekusazvibata kwemhasuru nekuita kwakasiyana kwemuviri.

Iyi mishonga inogona kubata akasiyana mamiriro, kubva kune yakanyanyisa kushanda dundira kune chisingaperi obstructive pulmonary disorder.