RA Kurapwa: DMARDs uye TNF-Alpha Inhibitors

Zvemukati

• Nhanganyaya
• DMARDs: Zvakakosha mukutanga kurapwa
• DMARD ane marwadzo
• Corticosteroids
• Kupfuura-iyo-counter NSAIDs
• Kunyorwa NSAIDs
• DMARD uye hutachiona
• TNF-alpha inhibitors
• Taura nachiremba wako
• Mubvunzo:
• A:

Nhanganyaya

Rheumatoid arthritis (RA) chirwere chisingagumi autoimmune. Izvo zvinoita kuti immune system yako irwise matukisi ane hutano mumajoini ako, zvichikonzera kurwadziwa, kuzvimba, uye kuomarara. Kusiyana neosteoarthritis, iyo inoguma neyakajairika kupfeka uye kubvarura paunenge uchikwegura, RA inogona kukanganisa chero munhu pazera ripi zvaro. Hapana anoziva kuti chii chinokonzeresa.

RA haina mushonga, asi mishonga inogona kubatsira kubvisa zviratidzo. Iyi mishonga inosanganisira anti-anogumbura zvinodhaka, corticosteroids, uye zvinodhaka zvinodzvinyirira immune system. Mimwe yemishonga yekurapa inodakadza ndeyekurapa-rheumatic drug (DMARDs), ayo anosanganisira TNF-alpha inhibitors.

DMARDs: Zvakakosha mukutanga kurapwa

DMARDs mishonga iyo rheumatologists inowanzo kupa mushure mekuongororwa kweRA. Zvizhinji zvekusingaperi kwekubatana kwemajoini kubva kuRA kunoitika mumakore maviri ekutanga, saka mishonga iyi inogona kukanganisa zvakanyanya kutanga kwechirwere.

DMARDs inoshanda nekuderedza immune system yako. Ichi chiito chinoderedza RA kurwisa kwemajoini ako kudzikisira iyo yakazara kukuvara.

Mienzaniso yeDMARD inosanganisira:

• methotrexate (Otrexup)
• hydroxychloroquine (Plaquenil)
• leflunomide (Arava)

DMARD ane marwadzo

Chinhu chakanyanya kudzikira pakushandisa maDMARD ndechekuti ivo vanononoka kuita. Zvinogona kutora mwedzi yakati wandei kuti unzwe chero zororo kubva kune DMARD. Nechikonzero ichi, rheumatologists vanowanzo gadza vanokurumidza-kuita painkiller senge corticosteroids kana nonsteroidal anti-anogumbura zvinodhaka (NSAIDs) kutora panguva imwe chete. Iyi mishonga inogona kubatsira kudzikamisa kurwadziwa paunenge wakamirira iyo DMARD kuti itange kushanda.

Mienzaniso yecorticosteroids kana NSAIDs inogona kushandiswa neDMARD inosanganisira:

Corticosteroids

• prednisone (Rayos)
• methylprednisolone (Depo-Medrol)
• triamcinolone (Aristospan)

Kupfuura-iyo-counter NSAIDs

• asipurini
• ibuprofen
• naproxen sodium

Kunyorwa NSAIDs

• nabumetone
• celecoxib (Celebrex)
• piroxicam (Feldene)

DMARD uye hutachiona

DMARD inokanganisa immune system yako yese. Izvi zvinoreva kuti vanokuisa panjodzi huru yekutapukirwa.

Zvirwere zvakajairika izvo varwere veRA vane izvi ndeizvi:

• hutachiona hweganda
• zvirwere zvepamusoro zvekufema
• chirwere chemabayo
• Urinary turakiti hutachiona

Kubatsira kudzivirira hutachiona, unofanirwa kudzidzira hutsanana, kusanganisira kugeza mawoko kazhinji uye kugeza zuva nezuva kana rimwe zuva. Iwe unofanirwawo kugara kure nevanhu vanorwara.

TNF-alpha inhibitors

Tumor necrosis factor alpha, kana TNF alpha, chinhu chinoitika zvakasikwa mumuviri wako. MuRA, immune system maseru anorwisa majoini anogadzira akakwira matanho eTNF alpha. Aya mazinga epamusoro anokonzera kurwadziwa nekuzvimba. Nepo zvimwe zvinhu zvinoverengeka zvinowedzera kukuvara kweRA mumajoini, TNF alpha mutambi mukuru mukuita.

Nekuti TNF alpha idambudziko rakakura muRA, TNF-alpha inhibitors ndeimwe yemhando dzakakosha dzeDMARDs pamusika izvozvi.

Kune mashanu marudzi eTNF-alpha inhibitors:

• adalimumab (Humira)
• etanercept (Enbrel)
• certolizumab pegol (Cimzia)
• golimumab (Simponi)
• infliximab (Remicade)

Iyi mishonga inonziwo TNF-alpha blockers nekuti inovhara zvinoitwa neTNF alpha. Ivo vanoderedza matanho eTNF alpha mumuviri wako kubatsira kudzikisa RA zviratidzo. Ivo zvakare vanotanga kushanda nekukurumidza kupfuura mamwe maDMARD. Vanogona kutanga kuitika mukati memavhiki maviri kusvika pamwedzi.

Taura nachiremba wako

Vanhu vazhinji vane RA vanopindura zvakanaka kune TNF-alpha inhibitors uye mamwe maDMARD, asi kune vamwe vanhu, idzi sarudzo dzinogona kusashanda zvachose. Kana ivo vasingakushandire iwe, udza rheumatologist yako. Ivo vangango gadza rakasiyana TNF-alpha inhibitor sedanho rinotevera, kana ivo vangangopa imwe mhando yeDMARD zvachose.

Ive neshuwa yekuvandudza yako rheumatologist pane kuti unonzwa sei uye kuti unofunga sei kuti mushonga wako uri kushanda. Pamwe chete, iwe nachiremba wako munogona kuwana chirongwa chekurapa RA icho chinokushandirai.

Mubvunzo:

Kudya kwangu kunogona kukanganisa RA yangu here?

A:

Ehe. Kune zvakawanda zvekudya zvinogona kubatsira kudzikisa kuzvimba mumuviri wako. Kana iwe uchida kuyedza shanduko yekudya kuti uvandudze RA zviratidzo, tanga nekudya zvimwe zvekudya zvine omega-3 fatty acids, antioxidants, uye fiber, senge nzungu, hove, majikiji, miriwo, uye girini tii. Imwe nzira yakanaka yekuunza izvi zvekudya muhupenyu hwako hwezuva nezuva ndeyekutevera chikafu cheMediterranean. Kuti uwane rumwe ruzivo nezve ichi chikafu uye zvimwe zvekudya izvo zvinogona kubatsira kudzikisira RA zviratidzo, tarisa iyo inorwisa-kupisa chikafu cheRA.