Zvese zvaunoda Kuti Uzive Nezve Endometrial (Uterine) Kenza

Zvemukati

• Ndezvipi zviratidzo zvegomarara remendometri?
• Ndeapi matanho ekenza yemendometriya?
• Kenza yemendometriari inoonekwa sei?
• Ndeapi marapirwo ekenza yemendometriya?
• Kuvhiya
• Radiation kurapa
• Chemotherapy
• Hormone kurapa
• Kutsigira mupfungwa
• Ndezvipi zvinhu zvine njodzi kukenza yemendometri?
• Mahormone mazinga
• Endometrial hyperplasia
• Kufutisa
• Chirwere cheshuga
• Nhoroondo yekenza
• Chii chinokonzera kenza yemendometrium?
• Ndeapi marudzi akasiyana ekenza yemendometri?
• Iwe unogona sei kudzikisa njodzi yako yekenza yemendometri?
• Kutora

Chii chinonzi Endometrial Cancer?

Endometrial kenza rudzi rwechibereko chechibereko chinotanga mukati memukati wechibereko. Lining iyi inonzi endometrium.

Sekureva kweNational Cancer Institute, vangangoita vatatu pavakadzi zana vanozoonekwa vaine chirwere checancer yechibereko pane imwe nguva muhupenyu hwavo. Vanopfuura makumi masere muzana yevanhu vane gomarara rechibereko vanorarama kwemakore mashanu kana kupfuura mushure mekuwana kuongororwa.

Kana uine kenza yemendometrial, kutanga kuongororwa uye kurapwa kunowedzera mikana yako yekuregererwa.

Ndezvipi zviratidzo zvegomarara remendometri?

Chiratidzo chakajairika chegomarara remendometriya kubuda ropa kwemukati. Izvi zvinogona kusanganisira:

• shanduko muhurefu kana huremu hwekuenda kumwedzi
• kubuda ropa kwemadzimai kana kuona pakati pemwedzi
• kusangana nekutsi kwemukadzi kubuda ropa mushure mekuguma kuenda kumwedzi

Zvimwe zvinogona kuve zviratidzo zvekenza yemendometri zvinosanganisira:

• yemvura kana yeropa-yakasungwa kusangana nekutsi kwemukadzi kubuda
• kurwadziwa muzasi kwedumbu kana chiuno
• kurwadziwa panguva yepabonde

Kana iwe ukasangana nechimwe cheizvi zviratidzo, ita musangano nachiremba wako. Zviratidzo izvi hazvireve hazvo kuti chiratidzo chechimiro chakakomba, asi zvakakosha kuti zviongororwe.

Kuwedzera kweropa kubuda mukati memukadzi kunowanzo kukonzerwa nekuguma kuenda kumwedzi kana zvimwewo zvisina gomarara. Asi mune zvimwe zviitiko, chiratidzo chekenza yemendometri kana mamwe marudzi ekenza yemadzimai.

Chiremba wako anogona kukubatsira kuti uone chinokonzera zviratidzo zvako uye kukurudzira kurapwa kwakakodzera, kana zvichidikanwa.

Ndeapi matanho ekenza yemendometriya?

Nekufamba kwenguva, kenza yemendometri inogona kupararira kubva muchibereko kuenda kune zvimwe zvikamu zvemuviri.

Gomarara rakaiswa muzvikamu zvina zvichibva pakukura kwarakaita kana kupararira.

• Chikamu 1: Gomarara riripo chete muchibereko.
• Chikamu chechipiri: Gomarara riripo muchibereko nemuchibereko.
• Chikamu chechitatu: Gomarara rapararira kunze kwechibereko, asi kwete kusvika kureba kana dundira. Inogona kunge iripo mumatopopian machubhu, mazai, mukadzi, uye / kana lymph node dziri padyo.
• Chikamu 4: Gomarara rapararira kupfuura nzvimbo yepachiuno. Inogona kunge iripo mudundira, rectum, uye / kana kure materu uye nhengo.

Kana munhu achinge aonekwa aine kenza yemendometriji, danho rekenza rinokanganisa nzira dzipi dzekurapa dziripo uye maonero erefu. Endometrial kenza iri nyore kurapa mumatanho ekutanga emamiriro acho.

Kenza yemendometriari inoonekwa sei?

Kana iwe ukaita zviratidzo zvinogona kuve endometrial cancer, ita musangano nachiremba wako wekutanga wekutarisira kana gynecologist. Gynecologist imhando yakasarudzika yechiremba inotarisa pane yevakadzi yekubereka system.

Chiremba wako achakubvunza nezve ako zviratidzo uye nhoroondo yekurapa. Vachaita bvunzo dzechiuno kuti vatarise uye vanzwe kusagadzikana muchibereko chako uye nedzimwe nhengo dzekubereka. Kuti utarise mamota kana zvimwe zvisina kujairika, vanogona kuraira transvaginal ultrasound bvunzo.

Kuongorora kwe ultrasound rudzi rwekuyedza imaging iyo inoshandisa mafungu ezwi kugadzira mifananidzo yemukati memuviri wako. Kuti uite transvaginal ultrasound, chiremba wako kana imwe nyanzvi yehutano ichaisa purofesa ye ultrasound mukati memukadzi wako. Iyi probe ichaendesa mifananidzo pane yekutarisa.

Kana chiremba wako akaona kusagadzikana panguva yekuongororwa kweiyo ultrasound, vanogona kuraira imwe kana yakawanda yeinotevera bvunzo kuti utore sampuro yeturu yekuyedza:

• Endometrial biopsy: Mumuedzo uyu, chiremba wako anoisa chubhu inopfava kuburikidza nemuromo wechibereko muchibereko chako. Ivo vanoisa kununura kubvisa chidimbu chidiki chemucheka kubva kune yako endometrium kuburikidza nehubhu.
• Hysteroscopy: Mune maitiro aya, chiremba wako anoisa chubhu inopfava inochinja ine fiber-optic kamera kuburikidza nemuromo wechibereko chako muchibereko chako. Ivo vanoshandisa iyi endoscope kuti vaone nemaziso ako endometrium uye biopsy masampula ezvakaipa.
• Kuzadza uye curettage (D&C): Kana mhedzisiro yeiyo biopsy isina kujeka, chiremba wako anogona kutora imwe sampuro yemanyowa endometrium achishandisa D & C. Kuti uite kudaro, vanorerutsa chibereko chako uye vanoshandisa chakakosha chishandiso kukwesha matissue kubva kune yako endometrium.

Mushure mekutora sampuro yetissue kubva kune yako endometrium, chiremba wako anozoitumira ku laboratori kunoedzwa. Nyanzvi yevarabhoritari ichaongorora muyenzaniso pasi pe microscope kuti ione kana iine cancer maseru.

Kana iwe uine kenza yemendometriamu, chiremba wako angango kuraira mimwe bvunzo kuti udzidze kana gomarara rapararira. Semuenzaniso, ivo vanogona kuraira kuongororwa kweropa, x-ray bvunzo, kana kumwe kuongorora kwekufungidzira.

Ndeapi marapirwo ekenza yemendometriya?

Kune nzira dzakasiyana dzekurapa dzinowanikwa kune endometrial cancer. Chirongwa chako chekurapa chakakurudzirwa nachiremba chako chinoenderana nekapasi uye chikamu chegomarara, pamwe nehutano hwako hwese uye zvaunofarira.

Pane zvinogona kubatsira uye njodzi dzakanangana neyese nzira yekurapa. Chiremba wako anogona kukubatsira kuti unzwisise zvingabatsire uye njodzi dzenzira imwe neimwe.

Kuvhiya

Kenza yeEndometrial inowanzo kurapwa nemhando yekuvhiya inozivikanwa seysterectomy.

Munguva ye hysterectomy, chiremba anovhiya anobvisa chibereko. Vanogona zvakare kubvisa maovari uye fallopian machubhu, mune maitiro anozivikanwa senyika mbiri salpingo-oophorectomy (BSO). Hysterectomy uye BSO zvinowanzoitwa panguva imwechete yekushanda.

Kuti udzidze kana gomarara rapararira, chiremba anovhiya achabvisawo ma lymph node ari padyo. Izvi zvinozivikanwa se lymph node dissection kana lymphadenectomy.

Kana kenza yapararira kune dzimwe nzvimbo dzomuviri, chiremba anovhiya anogona kukurudzira kumwe kuvhiya.

Radiation kurapa

Radiation kurapa kunoshandisa yakakwira-simba matanda kuuraya cancer maseru.

Kune maviri akakosha marudzi e radiation kurapwa anoshandiswa kurapa endometrial cancer.

• External beam radiation radiation kurapwa: Muchina wekunze unotarisa matanda emwaranzi pachibereko kubva kunze kwemuviri wako.
• Yemukati radiation radiation: Zvinhu zvine radioactive zvinoiswa mukati memuviri, mukati memukadzi kana chibereko. Izvi zvinozivikanwawo se brachytherapy.

Chiremba wako anogona kukurudzira imwe kana ese maviri marudzi e radiation kurapwa mushure mekuvhiyiwa. Izvi zvinogona kubatsira kuuraya cancer maseru ayo anogona kusara mushure mekuvhiyiwa.

Muzviitiko zvisingawanzoitika, vanogona kukurudzira kurapwa nemwaranzi vasati vavhiyiwa. Izvi zvinogona kubatsira kudzikira mamota kuti zviite nyore kubvisa.

Kana iwe usingakwanise kuvhiyiwa nekuda kwemamwe marapirwo kana hutano husina hutano, chiremba wako anogona kukurudzira kurapwa kwemwaranzi seyako yekurapa kukuru.

Chemotherapy

Chemotherapy inosanganisira kushandiswa kwemishonga kuuraya cancer maseru. Dzimwe mhando dzekemotherapy kurapwa dzinosanganisira mumwe mushonga, nepo mamwe anosanganisira musanganiswa wemishonga. Zvichienderana nerudzi rwemakemikari aunogashira, mishonga inogona kunge iri muchimiro chemapiritsi kana kupihwa kuburikidza nemutsinga (IV) mutsetse.

Chiremba wako anogona kukurudzira chemotherapy yekenza yemendometri yakapararira kune dzimwe nhengo dzomuviri. Ivo vanogona zvakare kukurudzira iyi nzira yekurapa yekenza yemendometri iyo yakadzoka mushure mekurapwa kwakapfuura.

Hormone kurapa

Kurapa kwehormone kunosanganisira kushandiswa kwemahormone kana madhiragi-anovharira mishonga kushandura mahormone emuviri. Izvi zvinogona kubatsira kudzora kukura kwemasero emukenza endometrial.

Chiremba wako anogona kukurudzira hutachiona hwechikamu chechitatu kana chegumi IV kenza yemendometrium. Ivo vanogona zvakare kuzvikurudzira kune endometrial kenza iyo yadzoka mushure mekurapwa.

Hormone therapy inowanzo kuve yakabatana ne chemotherapy.

Kutsigira mupfungwa

Kana iwe uchinetseka kubata nemanzwiro nekenza yako kuongororwa kana kurapwa, rega chiremba wako azive. Zvakajairika kuti vanhu vave nekunetseka kugadzirisa zvinoitika pamoyo nepfungwa zvekurarama nekenza.

Chiremba wako anogona kukuendesa kune ari-munhu kana online rutsigiro boka revanhu vane gomarara. Unogona kuzviwana zvichinyaradza kubatana nevamwe vari kusangana nezvakaitika zvakafanana newe.

Chiremba wako anogona zvakare kukuendesa iwe kune wehutano hwepfungwa nyanzvi yezano. Imwe-on-one kana kurapwa kwechikwata kunogona kukubatsira iwe kugadzirisa zvepfungwa uye zvemagariro mhedzisiro yekurarama nekenza.

Ndezvipi zvinhu zvine njodzi kukenza yemendometri?

Ngozi yekenza yemendometri inowedzera nezera. Kazhinji nyaya dzekenza yemendometri dzinowanikwa dziri pakati pemakore makumi mana nemana nemanomwe nemanomwe ekuberekwa, inoshuma National Cancer Institute.

Zvimwe zvakati wandei zvinhu zvine njodzi zvinogona kukwidziridza njodzi yekenza yemendometri, kusanganisira:

• shanduko mune mahormone ebonde
• mamwe marapirwo
• nhoroondo yemhuri yekenza

Mahormone mazinga

Estrogen uye progesterone mahormone echikadzi echikadzi anokanganisa hutano hweiyo endometrium. Kana chiyero cheaya mahormone chichienda kune yakawedzera esrogen mazinga, inokwidza njodzi yako yekuva nekenza yemendometri.

Zvimwe zvinhu zveyako nhoroondo yezvokurapa zvinogona kukanganisa ako ehupombwe mahormone uye njodzi yekenza yemendometri, inosanganisira:

• Makore ekuenda kumwedzi: Iyo yakawanda nguva yekuenda kumwedzi iyo iwe yawakave nayo muhupenyu hwako, iyo inowedzera kuratidzwa muviri wako kwave kune estrogen. Kana iwe ukawana nguva yako yekutanga usati wave nemakore gumi nemaviri kana kuti ukapfuura nekumira kwemwedzi kunonoka muhupenyu, unogona kunge uri munjodzi yekuwedzera yekenza yemendometri.
• Nhoroondo yekuzvitakura: Panguva yekuzvitakura, muyero wehomoni inochinja uchienda kune progesterone.Kana iwe usati wambove nepamuviri, mikana yako yekuva nekenza yemendometri inowedzera.
• Polycystic ovarian chirwere (PCOS): Mune iri dambudziko rehormone, eestrogen mazinga akakwirira uye mwero weprogesterone wakadzikira zvakanyanya. Kana iwe uine nhoroondo yePCOS, mikana yako yekuwana gomarara remendometri inowedzerwa.
• Granulosa maseru mamota:Granulosa cell tumors rudzi rwe ovarian bundu rinosunungura estrogen. Kana iwe uine rimwe remamota aya, zvinomutsa njodzi yako yekenza yemendometrium.

Mimwe mhando yemishonga inogona zvakare kuchinja muyero weestrogen uye progesterone mumuviri wako, kusanganisira:

• Estrogen kutsiva kurapa (ERT): ERT dzimwe nguva inoshandiswa kurapa zviratidzo zvekuguma kuenda kumwedzi. Kusiyana nemamwe marudzi ehomoni kutsiva kurapa (HRT) inosanganisa estrogen uye progesterone (progestin), ERT inoshandisa estrogen yega uye inokwidza njodzi yako yekenza yemendometri.
• Tamoxifan: Mushonga uyu unoshandiswa kubatsira kudzivirira uye kubata mamwe marudzi ekenza yemazamu. Iyo inogona kuita sestrogen muchibereko chako uye kusimudza endometrial kenza njodzi.
• Zvirongwa zvekudzivirira zvemumuromo (mapiritsi ekuberekwa): Kutora mapiritsi ekudzivirira kubereka kunoderedza njodzi yako yekenza yemendometrium. Kana iwe uchivatora kwenguva refu, iyo inoderedza njodzi yako yekenza yemendometri.

Mishonga inosimudza njodzi yako yekenza yemendometri inogona kudzikisa njodzi yako yemamwe mamiriro. Zvakare, zvinodhaka izvo zvinoderedza njodzi yako yekenza yemendometri zvinogona kukwidza njodzi yako yemamwe mamiriro.

Chiremba wako anogona kukubatsira kuyera zvingabatsire uye njodzi dzekutora mishonga yakasiyana, kusanganisira ERT, tamoxifan, kana mapiritsi ekudzivirira kubereka.

Endometrial hyperplasia

Endometrial hyperplasia isiri-kenza mamiriro, umo yako endometrium inova isina kujairika gobvu. Mune zvimwe zviitiko, inoenda yega. Mune zvimwe zviitiko, inogona kurapwa neHRT kana kuvhiyiwa.

Kana ikasiiwa isingarapwe, endometrial hyperplasia dzimwe nguva inokura kuita cancer yegomarara.

Chiratidzo chakajairika cheendometrial hyperplasia ndeyekusarongeka kwemukadzi kubuda ropa.

Kufutisa

Sekureva kweAmerican Cancer Society, vakadzi vane huremu hwakanyanya (BMI 25 kusvika 29.9) vane mukana wakapetwa kaviri wekubata gomarara remudumbu sevakadzi vasina kunyanya kufuta. Avo vane kufutisa (BMI> 30) vanodarika katatu mukana wekuvandudza rudzi urwu rwegomarara.

Izvi zvinogona kuratidza zvinoitika zvine mafuta emuviri pamatanho eestrogen. Mafuta emafuta anogona kushandura mamwe marudzi emahomoni (androgens) kuita estrogen. Izvi zvinogona kukwidza mwero weestrogen mumuviri, zvichiwedzera njodzi yekenza yemendometrium.

Chirwere cheshuga

Vakadzi vane rudzi rwechipiri chirwere cheshuga vanogona kunge vangangoita zvakapetwa kaviri kuita cancer yegomometri sevaya vasina chirwere cheshuga, inoyambira American Cancer Society.

Zvisinei, chimiro cheiyi link hachina chokwadi. Rudzi rwechipiri chirwere cheshuga chinowanzoitika kune vanhu vane huremu hwakanyanya kana vane kufutisa, inova zvakare njodzi kune kenza yemendometri. Iyo yakakwira mwero wekuneta muvanhu vane mhando 2 chirwere cheshuga inogona kuverengerana kune yakawedzera njodzi yekenza yemendometri.

Nhoroondo yekenza

Iwe unowanzoita gomarara remendometri kana dzimwe nhengo dzemhuri yako dzave narwo.

Iwe zvakare uri panjodzi yekuwedzera yekenza yemendometri kana uine nhoroondo yemhuri yeLynch syndrome. Aya mamiriro anokonzerwa nekuchinja mune rimwe kana akawanda emajeni anogadzirisa zvimwe zvikanganiso mukukudziridzwa kwesero.

Kana iwe uine magene ekuchinja anoenderana neLynch syndrome, inowedzera zvakanyanya njodzi yako yemamwe marudzi ekenza, kusanganisira colon cancer uye endometrial cancer. Zvinoenderana nekudzokorora kwakaburitswa mumagazini yeGenes, makumi mana kusvika makumi matanhatu muzana evakadzi vane Lynch syndrome vanoita gomarara remudumbu.

Kana iwe wakambove nekenza yemazamu kana ovari kenza munguva yakapfuura, izvo zvinogona zvakare kukwidza njodzi yako yekenza yemendometri. Zvimwe zvezviitiko zvengozi zvegomarara izvi zvakafanana. Radiation kurapwa pane yako pelvis inogona zvakare kukwidziridza mikana yako yekuvandudza endometrial cancer.

Chii chinokonzera kenza yemendometrium?

Muzviitiko zvakawanda, chikonzero chaicho chekenza yemendometrium hachizivikanwe. Nekudaro, nyanzvi dzinofunga kuti shanduko padanho reestrogen uye progesterone mumuviri inowanzoita chikamu.

Kana iwo mahormone eaya ebonde mahormone achichinja, zvinokanganisa yako endometrium. Kana iyo bhalanzi ichichinjira kune yakawedzera mazinga eestrogen, inokonzeresa masendometriya maseru kuti apatsanure uye awande.

Kana kumwe kuchinja kwemajini kuchiitika mumasero endometrium, anova kenza. Aya maseru ekenza anokurumidza kukura uye kuwanda kuita bundu.

Masayendisiti achiri kuongorora shanduko dzinokonzeresa masero endometriamu kuita maseru ekenza.

Ndeapi marudzi akasiyana ekenza yemendometri?

IAmerican Cancer Society inoshuma kuti mazhinji emakenza endometriamu adenocarcinomas. Adenocarcinomas ndiwo kanzira dzinokura kubva paglandular tishu. Rudzi rwakakurumbira rweadenocarcinoma igomarara ye endometrioid.

Pasina kujairika mafomu ekenza yemendometri anosanganisira:

• uterine carcinosarcoma (CS)
• squamous cell carcinoma
• diki sero carcinoma
• shanduko carcinoma
• serous carcinoma

Mhando dzakasiyana dzekenza yemendometri inorongedzwa kuita maviri makuru mhando:

• Tora 1 inowanzo kuve inononoka kukura uye usapararire nekukurumidza kune mamwe matishu.
• Tora 2 inowanzo kuve ine hukasha uye inogona kuparira kunze kwechibereko.

Nyora 1 kenza yemendometrial yakajairika kupfuura mhando 2. Izvo zvakare zviri nyore kurapa.

Iwe unogona sei kudzikisa njodzi yako yekenza yemendometri?

Dzimwe nzira dzinogona kukubatsira kudzikisa njodzi yako yekuva nekenza yemendometrium:

• Chengetedza uremu hwako: Kana iwe uri kuwandisa kana kufutisa, kurasikirwa uremu uye kuchengetedza huremu hunogona kudzikisira njodzi yako yekenza yemendometri. Kumwe kutsvagurudza kunodiwa kuti udzidze kuti kurema kunokanganisa sei njodzi yekenza yemendometri.
• Gara uchiita maekisesaizi: Kugara uchirovedza muviri kwakabatanidzwa nenjodzi yakaderera yekenza yemendometri. Iinewo mamwe akawanda mabhenefiti ehutano.
• Tsvaga kurapwa kweakajairika kusangana nekutsi kwemukadzi kubuda ropa: Kana iwe ukava nekusajairika kusangana nekutsi kwemukadzi kubuda ropa, ita musangano nachiremba wako. Kana kubuda ropa kuchikonzerwa ne endometrial hyperplasia, bvunza chiremba wako nezve nzira dzekurapa.
• Funga nezve zvayakanakira nezvayakaipira kurapa kwehomoni: Kana iwe uri kufunga nezvekushandisa HRT, bvunza chiremba wako nezve zvingabatsire uye njodzi dzekushandisa estrogen yega maringe nekubatanidzwa kwesrogen uye progesterone (progestin). Ivo vanogona kukubatsira kuyera imwe neimwe sarudzo.
• Kumbira chiremba wako nezve zvingabatsire zvekudzivirira kubata pamuviri. Mapiritsi ekudzivirira kuberekwa uye michina ye intrauterine (IUDs) zvakabatanidzwa kune yakaderera ngozi yekenza yemendometri. Chiremba wako anogona kukubatsira iwe kuti udzidze nezve zvingabatsire uye njodzi dzekushandisa izvi zvekudzivirira.
• Rega chiremba wako azive kana iwe uine nhoroondo yeLynch syndrome: Kana mhuri yako iine nhoroondo yeLynch syndrome, chiremba wako anogona kukurudzira kuongororwa kwemajini. Kana uine Lynch syndrome, vanogona kukukurudzira kuti ufunge nezvako chibereko, mazai, uye fallopian machubhu anobviswa kudzivirira cancer kubva mukukura mune izvo nhengo.

Kutora

Kana iwe uine zviratidzo zvinogona kuve chiratidzo chekenza yemendometri kana imwe gynecological mamiriro, ita musangano nachiremba wako. Kuongorora kwekutanga uye kurapwa kunogona kubatsira kuvandudza maonero ako kwenguva refu.