Chinhu VII Kushaikwa

Zvemukati

• Chii chinotora chinzvimbo VII mukutamba mukugwamba kweropa?
• 1. Vasoconstriction
• 2. Kuumbwa kweplatelet plug
• 3. Kugadzirwa kwefibrin plug
• 4. Kukuvara kupora uye kuparadzwa kweiyo firin plug
• Chii chinokonzera kushomeka kwechikonzero VII?
• Ndezvipi zviratidzo zvekushomeka kwechikonzero VII?
• Chinhu chinoshomeka cheVII chinowanikwa sei?
• Kushomeka kwechikonzero VII kunoitwa sei?
• Kudzora kubuda ropa
• Kurapa kwemamiriro ezvinhu
• Kuchengetedza kurapwa usati wavhiyiwa
• Ndeupi mutarisiro wenguva refu?

Mhedziso

Chinhu cheVII kushomeka chirwere chekuvhara ropa chinokonzera kubuda kwakanyanya kana kwenguva refu mushure mekukuvara kana kuvhiyiwa. Uine kushomeka kwechikonzero VII, muviri wako pamwe haugadzire zvakakwana chinhu VII, kana chimwe chinhu chiri kupokana nechako VII, kazhinji chimwe chirwere.

Chinhu VII ipuroteni inogadzirwa muchiropa iyo inoita basa rakakosha pakubatsira ropa rako kugwamba. Icho chimwe chezvinhu zvingangosvika makumi maviri ekugwamba zvinobatanidzwa mukuoma kwakaomarara kweropa. Kuti unzwisise kushomeka kwechikonzero VII, zvinobatsira kuti unzwisise chikamu chei VII chinotamba mukugwamba kweropa.

Chii chinotora chinzvimbo VII mukutamba mukugwamba kweropa?

Iyo yakajairika nzira yekuvhara ropa inoitika mumatanho mana:

1. Vasoconstriction

Kana tsinga yeropa ikatemwa, iyo yeropa yakakanganisika inokurumidza kudzora kurasikirwa neropa. Ipapo, iro reropa rakakuvara rinoburitsa puroteni inonzi tishu chinhu muropa. Kuburitswa kwetissue factor kunoita senge kufona kweSOS, ichiratidza maplatelet eropa uye zvimwe zvinogumbura zvekumhan'ara kunzvimbo yekukuvara.

2. Kuumbwa kweplatelet plug

Maplatelet muropa reropa ndiwo anotanga kusvika panzvimbo yekukuvara. Vanozvibatanidza nehuturu hwakakanganisika, uye kune mumwe nemumwe, vachigadzira purogi yenguva pfupi, yakapfava muronda. Izvi zvinozivikanwa seyekutanga hemostasis.

3. Kugadzirwa kwefibrin plug

Kamwe puraki yenguva pfupi painenge yavapo, izvo zvinogwamba zveropa zvinopinda nenzira yakaoma yeketani kuti isunungure fibrin, yakaoma, ine tambo protein. Fibrin inozviputira mukati uye nekukomberedza iro rakapfava clot kusvikira raita rakaomarara, risingaputsike fibrin clot. Iri jira idzva rinonama iro rakaputsika reropa, uye rinogadzira chifukidzo chekudzivirira chekukura kwenyama nyowani.

4. Kukuvara kupora uye kuparadzwa kweiyo firin plug

Mushure memazuva mashoma, iyo fibrin clot inotanga kudzikira, ichidhonza mativi eronda pamwechete kuti ibatsire nyama nyowani kukura pamusoro pechironda. Sezvo zvinyama zvinovakwazve, iyo fibrin clot inonyungudika uye inosvirwa.

Kana chinhu VII chisingashande nemazvo, kana paine zvishoma zvacho, yakasimba fibrin clot haigone kuumba mushe.

Chii chinokonzera kushomeka kwechikonzero VII?

Chinhu cheVII kushomeka chinogona kunge chakagarwa nhaka kana kutorwa. Iyo vhezheni vhezheni haina kujairika. Mashoma pane mazana maviri emakesi akanyorwa akataurwa. Vabereki vako vese vanofanira kutakura geni kuti iwe ubatwe.

Yakawana chinhu VII kushomeka, mukupesana, kunoitika mushure mekuzvarwa. Izvo zvinogona kuitika semhedzisiro yemishonga kana zvirwere zvinokanganisa chinhu chako VII. Zvinodhaka zvinogona kukanganisa kana kudzikisira chinhu VII basa zvinosanganisira:

• mishonga inorwisa mabhakitiriya
• vanoonda ropa, senge warfarin
• mimwe mishonga yekenza, senge interleukin-2 kurapa
• antithymocyte globulin therapy inoshandiswa kurapa aplastic anemia

Zvirwere uye zvekurapa mamiriro anogona kukanganisa chinhu VII anosanganisira:

• chirwere chechiropa
• myeloma
• sepsis
• aplastic kupererwa neropa
• vhitamini K kushomeka

Ndezvipi zviratidzo zvekushomeka kwechikonzero VII?

Zviratidzo zvinosiyana kubva pane zvinyoro kusvika kune zvakanyanya, zvinoenderana nematanho ako ekushandisa chinhu VII. Zviratidzo zvinyoro zvinogona kusanganisira:

• kupwanya uye zvinyoro nyoro kubuda ropa
• nguva yakareba yekubuda ropa kubva kumaronda kana kubviswa kwemazino
• kubuda ropa mumajoini
• mhino dzemhino
• maronda anobuda ropa
• kuenda kumwedzi kunorema

Muzviitiko zvakanyanya, zviratidzo zvinogona kusanganisira:

• kuparadzwa kwekatekete muzvibatanidzwa kubva muzvikamu zvekubuda ropa
• kubuda ropa mumatumbu, mudumbu, mhasuru, kana musoro
• kubuda ropa zvakanyanya mushure mekusununguka

Chinhu chinoshomeka cheVII chinowanikwa sei?

Kuongororwa kwakavakirwa pane yako nhoroondo yezvokurapa, chero nhoroondo yemhuri yezvinetso zvekubuda ropa, uye bvunzo bvunzo.

Lab kuyedzwa kwechikonzero VII kushomeka kunosanganisira:

• chinhu chekuyedza kuratidza kushayikwa kana kuita zvisirizvo
• chinhu VII kuyera kuyera kuti yakawanda sei factor VII yaunayo, uye kuti inoshanda zvakadii
• prothrombin nguva (PT) kuyera mashandiro ezvinhu I, II, V, VII, uye X
• chikamu prothrombin nguva (PTT) kuyera mashandiro ezvinhu VIII, IX, XI, XII, uye von Willebrand zvinhu
• inhibitor bvunzo kuti uone kana immune system yako iri kurwisa yako yekugwamba

Kushomeka kwechikonzero VII kunoitwa sei?

Kurapa kwechinhu VII kushomeka kunotarisa pane:

• kudzora kubuda ropa
• kugadzirisa mamiriro ezvinhu
• kuchengetedza kurapwa usati wavhiyiwa kana maitiro emazino

Kudzora kubuda ropa

Munguva dzekubuda ropa zvikamu, iwe unogona kupihwa infusions yeropa inogwamba zvinhu kuti uwedzere kugona kwako kwekugwamba. Kuvhara vamiririri vanowanzo shandiswa vanosanganisira:

• munhu prothrombin yakaoma
• cryoprecipitate
• yakachena chando plasma
• recombinant human factor VIIa (NovoSeven)

Kurapa kwemamiriro ezvinhu

Kamwe kubuda ropa kuri pasi pekutonga, mamiriro ezvinhu anokanganisa kugadzirwa kweVII kana kushanda, senge mishonga kana zvirwere, inofanirwa kugadziriswa.

Kuchengetedza kurapwa usati wavhiyiwa

Kana iwe uri kuronga kuvhiya, chiremba wako anogona kukunyorera zvinodhaka kuti uderedze njodzi yako yekubuda ropa zvakanyanya. Desmopressin nasal spray inowanzo gadzirirwa kuburitsa zvese zviripo zvitoro zve factor VII pamberi pekuvhiyiwa kudiki. Kune mamwe maoparesheni akakomba, chiremba wako anogona kukuraira infusions yekugwamba kwechinhu.

Ndeupi mutarisiro wenguva refu?

Kana iwe uine fomu yawakawana yechinhu VII kushomeka, zvinogona kunge zvichikonzerwa nemushonga kana nemamiriro ezvinhu ari pasi. Maonero ako kwenguva refu anoenderana nekugadzirisa izvo zviri kukonzera matambudziko. Kana iwe uine iyo yakaoma kwazvo nhaka fomu yechinhu VII kushomeka, iwe uchafanirwa kushanda pamwe nachiremba wako nenzvimbo yako yemunharaunda hemophilia centre kugadzirisa njodzi dzekubuda ropa.