Lambert-Eaton Myasthenic Syndrome

Zvemukati

• Ndezvipi Zviratidzo zveLambert-Eaton Myasthenic Syndrome?
• Chii Chinokonzera Lambert-Eaton Myasthenic Syndrome?
• Kuongorora Lambert-Eaton Myasthenic Syndrome
• Kurapa Lambert-Eaton Myasthenic Syndrome
• Ndeapi Maonero Ekureba-Kure?

Chii chinonzi Lambert-Eaton Myasthenic Syndrome?

Lambert-Eaton myasthenic syndrome (LEMS) chirwere chisingawanzoite autoimmune chinokanganisa kugona kwako kufamba. Yako immune system inorwisa mhasuru nyama izvo zvinotungamira mukunetseka kufamba uye mamwe matambudziko emhasuru.

Hosha yacho haigone kurapwa, asi zviratidzo zvinogona kudzikira kana uchizvishandisa nesimba. Iwe unogona kubata mamiriro acho nemishonga.

Ndezvipi Zviratidzo zveLambert-Eaton Myasthenic Syndrome?

Zviratidzo zvekutanga zveLEMS kushaya simba kwemakumbo uye kunetseka kufamba. Sezvo chirwere ichi chichienderera mberi, iwe uchazoonawo:

• kushaya simba mumisungo yechiso
• zvisingaite musuru zviratidzo
• kuvimbiswa
• muromo wakaoma
• kushaya simba
• matambudziko edundira

Kushaya simba kwemakumbo kunowanzoita nani kwenguva pfupi pakuedza. Sezvo iwe uchirovedza muviri, acetylcholine inovaka muhombe zvakakwana zvakakwana kubvumira simba kuti riwedzere kwenguva pfupi.

Kune akawanda matambudziko anosangana neEMEMS. Izvi zvinosanganisira:

• kunetseka kufema uye kumedza
• zvirwere
• kukuvara nekuda kwekudonha kana matambudziko nekubatana

Chii Chinokonzera Lambert-Eaton Myasthenic Syndrome?

Muchirwere che autoimmune, immune system yako inokanganisa muviri wako pachinhu chekunze. Immune system yako inogadzira masoja anorwisa muviri wako.

MuLEMS, muviri wako unorwisa matinji anodzora huwandu hweacetylcholineyunoburitswa nemuviri wako. Acetylcholine inonzi neurotransmitter inokonzeresa kusagadzikana kwemhasuru. Tsinga dzemhasuru dzinokutendera iwe kuita mafambiro ekuzvidira senge kufamba, kupuruzira minwe yako, uye kukwenya mapendekete ako.

Kunyanya, muviri wako unorwisa puroteni inonzi voltage gated calcium chiteshi (VGCC). VGCC inodikanwa kuti isunungurwe acetylcholine. Iwe haugadzi acetylcholine yakakwana kana VGCC ichirwiswa, saka mhasuru dzako hadzikwanise kushanda nemazvo.

Zviitiko zvakawanda zveLEMS zvinosanganiswa nekenza yemapapu. Vatsvagiri vanotenda kuti maseru ekenza anogadzira iyo VGCC protein. Izvi zvinoita kuti immune system yako igadzire masoja ekudzivirira VGCC. Aya ma antibodies anobva arwisa ese maseru ekenza nemaseru etsandanyama. Chero ani zvake anogona kuvandudza LEMS muhupenyu hwavo, asi kenza yemapapu inogona kuwedzera njodzi yako yekukudziridza mamiriro acho. Kana paine nhoroondo yezvirwere zve autoimmune mumhuri yako, unogona kunge uri panjodzi huru yekuvandudza LEMS.

Kuongorora Lambert-Eaton Myasthenic Syndrome

Kuti uongorore LEMS, chiremba wako achatora nhoroondo yakajeka uye oongorora muviri. Chiremba wako achatsvaga:

• kuderera kwekufungisisa
• tsandanyama kurasikirwa
• kushaya simba kana kunetseka kufamba izvo zvinova nani nebasa

Chiremba wako anogona kuraira bvunzo dzinoverengeka kuti asimbise mamiriro acho. Kuongororwa kweropa kunotsvaga masoja ekudzivirira anorwisa VGCC (anti-VGCC antibodies). Iyo electromyography (EMG) inoongorora yako mhasuru fibers nekuona maitiro avanogadzira pavanosimudzirwa. Tsono diki inoiswa mumhasuru uye yakabatana nemamita. Iwe unozobvunzwa kuti ubate iyo mhasuru, uye iyo mita ichaverenga kuti masuru ako anopindura sei.

Imwe bvunzo inogona kuitika ndeye nerve conduction velocity test (NCV). Pamuedzo uyu, chiremba wako anoisa ma electrode pamusoro peganda rako rinofukidza mhasuru huru. Zvimedu zvinopa chiratidzo chemagetsi chinosimudzira tsinga nemhasuru. Basa rinoitika kubva mutsinga rinorekodhwa nemamwe maelektroni uye rinoshandiswa kutsvaga kukurumidza kwekuti tsinga dzinoita sei pakukurudzira.

Kurapa Lambert-Eaton Myasthenic Syndrome

Iyi mamiriro haigone kurapwa. Iwe uchashanda nachiremba wako kugadzirisa chero mamwe mamiriro, senge kenza yemapapu.

Chiremba wako anogona kukurudzira kurapwa kweiyo immunoglobulin (IVIG) kurapwa. Pakurapwa uku, chiremba wako anozobaya anti-yakatarwa antibody iyo inonyaradza immune system. Imwe inogona kurapwa kurapwa plasmapheresis. Ropa rinobviswa mumuviri, uye plasma inoparadzaniswa kunze. Masoja ekudzivirira chirwere anobviswa, uye plasma inodzorerwa mumuviri.

Zvinodhaka zvinoshanda neyako tsandanyama system dzimwe nguva zvinodzora zviratidzo. Izvi zvinosanganisira mestinon (pyridostigmine) uye 3, 4 diaminopyridine (3, 4-DAP).

Iyi mishonga yakaoma kuwana, uye iwe unofanirwa kutaura nachiremba wako kuti uwane rumwe ruzivo.

Ndeapi Maonero Ekureba-Kure?

Zviratidzo zvinogona kusimuka nekurapa mamwe mamiriro ezvinhu, kudzvinyirira immune system, kana kubvisa masoja ekudzivirira kubva muropa. Haasi munhu wese anopindura zvakanaka pakurapwa. Shanda nachiremba wako kuti uwane chirongwa chakakodzera chekurapa.