Chii chinonzi Methotrexate?
Zvemukati
- Chii ichochi
- Kushandisa sei
- 1. Rheumatoid yemajoini
- 2. Psoriasis
- 3. Gomarara
- Zvinogona kuitika mhedzisiro
- Ndiani asingafanire kushandisa
Methotrexate piritsi imushonga unoratidzirwa pakurapa rheumatoid arthritis uye yakakomba psoriasis iyo isinga pindure kune mamwe marapirwo. Uye zvakare, methotrexate inowanikwawo seinobaya jekiseni, inoshandiswa mune chemotherapy yekurapa kenza.
Mushonga uyu unowanikwa muchimiro chepiritsi kana jekiseni uye unogona kuwanikwa mumafarasi pasi pemazita eTecnomet, Enbrel uye Endofolin, semuenzaniso.
Chii ichochi
Methotrexate mumapiritsi inoratidzirwa pakurapa rheumatoid arthritis, sezvo iine zvinokanganisa immune system, kudzikira kwekuzvimba, chiito chayo chiri kucherechedzwa kubva muvhiki rechitatu rekurapwa.Mukurapa kwe psoriasis, methotrexate inoderedza kuwanda uye kuzvimba kwemasero eganda uye mhedzisiro yaro inoonekwa 1 kusvika 4 mavhiki mushure mekutanga kwekurapa.
Injectable methotrexate inoratidzirwa kurapa zvakanyanya psoriasis uye anotevera marudzi ekenza:
- Gestational trophoblastic neoplasms;
- Acute lymphocytic leukemias;
- Diki kenza yemapapu kenza;
- Kenza yemusoro neyemutsipa;
- Gomarara repazamu;
- Osteosarcoma;
- Kurapa uye prophylaxis ye lymphoma kana meningeal leukemia;
- Palliative kurapa kune isingashande yakasimba mamota;
- Asiri-Hodgkin's lymphomas uye Burkitt's lymphoma.
Kushandisa sei
1. Rheumatoid yemajoini
Iyo yakakurudzirwa yemumuromo yedosi inogona kuve 7.5 mg, kamwe chete pasvondo kana 2.5 mg, ese maawa gumi nemaviri, kwemitatu matatu, inoitiswa sedenderedzwa, kamwe pasvondo.
Iwo madosi eiyo yega regimen anofanirwa kugadziriswa zvishoma nezvishoma kuti uwane mhinduro yakakwana, asi haifanire kupfuudza muyero wevhiki rese we20 mg.
2. Psoriasis
Iyo yakakurudzirwa yemumuromo yedosi ndeye 10 - 25 mg pavhiki, kusvikira mhinduro yakakwana yawanikwa kana, neimwe nzira, 2.5 mg, maawa ese gumi nemaviri, kwemitero mitatu.
Iyo madhisheni mune yega regimen inogona kugadziriswa zvishoma nezvishoma kuti ibudirire yakakwana yekiriniki mhinduro, ichidzivirira kupfuura muyero we30 mg pasvondo.
Kwezviitiko zveakakomba psoriasis, panoshandiswa jekiseni methotrexate, imwe chete dhosi yegumi nemashanu kusvika makumi maviri neshanu pavhiki inofanira kupihwa kusvikira mhinduro yakakwana yawanikwa. Dzidza kuona zviratidzo zve psoriasis uye chii chakakosha hanya chaunofanira kutora.
3. Gomarara
Iyo yekurapa dhizaini yemethotrexate yezviratidzo zve oncological yakafara kwazvo, zvichienderana nerudzi rwekenza, huremu hwemuviri uye mamiriro emurwere.
Zvinogona kuitika mhedzisiro
Mhedzisiro inowanzoitika panguva yekurapwa nemapiritsi e methotrexate ane musoro wakakomba, kuomesa kwemutsipa, kurutsa, kupisa muviri, kutsvuka kweganda, kuwedzera uric acid uye kudzikisira huwandu hwehurume, kutaridzika kwemaronda emumuromo, kuzvimba kwerurimi uye matadza, manyoka, yakaderedzwa chena masero eropa uye platelet kuverenga, itsvo kutadza uye pharyngitis.
Ndiani asingafanire kushandisa
Methotrexate piritsi inopesana nevarwere vane allergies kune methotrexate kana chero chinhu chekuumbwa, vakadzi vane nhumbu, vakadzi vanoyamwisa, vanhu vane hutachiona hwehutachiona hwakakomba, chiropa chakakomba kana itsvo kusagadzikana uye shanduko mumasero eropa akadai sekudzikiswa kweropa masero machena eropa, tsvuku masero eropa nemaplatelet.