Inotyisa Epidermal Necrolysis: chii icho, zviratidzo uye marapirwo anoitwa

Zvemukati

• NET zviratidzo
• Zvinokonzera
• Kurapwa kunoitwa sei
• Maitiro ekuongororwa kunoitwa

Systemic epidermal necrolysis, kana NET, chirwere cheganda chisingawanzozivikanwa chinoonekwa nekuvapo kwemaronda mumuviri wese izvo zvinogona kutungamira mukusvuurwa kweganda zvachose. Chirwere ichi chinonyanya kukonzerwa nekushandiswa kwemishonga yakadai seAllopurinol neCarbamazepine, asi inogona zvakare kuve mhedzisiro yehutachiona kana hutachiona hutachiona, semuenzaniso.

NET inorwadza uye inogona kuuraya inosvika makumi matatu muzana ezviitiko, saka pachangotanga zviratidzo zvekutanga, zvakakosha kuti ubvunze dermatologist kuitira kuti kuongororwa kusimbiswe uye kurapwa kwatanga.

Kurapa kunoitwa muIntensive Care Unit uye kunoitwa kunyanya nekumiswa kwemushonga uri kukonzera chirwere. Uye zvakare, nekuda kwekuratidzwa kweganda uye mucosa, matanho ekudzivirira anotorwa kudzivirira hutachiona hwechipatara, izvo zvinogona kuwedzera kukanganisa mamiriro emakiriniki emurwere.

NET zviratidzo

Chiratidzo chinonyanya kuzivikanwa chehuturu epidermal necrolysis kukuvara kweganda mune anopfuura makumi matatu muzana emuviri anogona kubuda ropa uye kuburitsa zvinwiwa, achifarira kupera mvura mumuviri uye hutachiona.

Zviratidzo zvikuru zvakafanana nefuruu, semuenzaniso:

• Malaise;
• Kupisa zvakanyanya;
• Kukosora;
• Tsvina uye kurwadza kwemajoini.

Zviratidzo izvi, zvakadaro, zvinonyangarika mushure memazuva 2-3 uye zvinoteverwa ne:

• Mapundu eganda, anogona kubuda ropa uye kurwadza;
• Necrosis nzvimbo dzakakomberedza maronda;
• Ganda kubvarura;
• Blistering;
• Shanduko mugadziriro yekugaya nekuda kwekuvapo kwezvironda mumucosa;
• Kubuda kwemaronda mumuromo, huro uye anus, zvishoma kazhinji;
• Kuzvimba kwemaziso.

Maronda anobva kune chepfu epidermal necrolysis anoitika mune angangoita muviri wese, kusiyana naStevens-Johnson Syndrome, iyo kunyangwe iine kuratidzwa kumwechete kwekiriniki, kuongororwa pamwe nekurapwa, maronda acho akanyanyowanda mutangi, kumeso nepachipfuva. Dzidza zvakawanda nezvaStevens-Johnson Syndrome.

Zvinokonzera

Inotyisa epidermal necrolysis inonyanya kukonzerwa nemishonga, senge Allopurinol, Sulfonamide, anticonvulsants kana antiepileptics, senge Carbamazepine, Phenytoin uye Phenobarbital, semuenzaniso. Pamusoro pezvo, vanhu vane autoimmune zvirwere, senge Systemic Lupus Erythematosus, kana vane immune system yakadzikama, senge AIDS, vanowanzo kuve nemaronda eganda anoratidza necrolysis.

Kunze kwekukonzerwa nemishonga, zvipembenene zveganda zvinogona kuitika nekuda kwehutachiona nemavhairasi, fungi, protozoa kana bhakitiriya uye kuvepo kwemamota. Chirwere ichi chinogona zvakare kukanganiswa nekuchembera uye nemajini zvinhu.

Kurapwa kunoitwa sei

Kurapa kwehuturu epidermal necrolysis kunoitwa muIntensive Care Unit yekutsva uye inosanganisira kubviswa kwemushonga uyo urikushandiswa nemurwere, nekuti kazhinji iyo NET mhedzisiro yekushomeka kwemamwe mishonga.

Uye zvakare, kutsiva zvinwiwa uye maelectrolyte akarasika nekuda kweakakura maronda eganda kunoitwa nekupinza serum mutsinga. Kuchengetwa kwemazuva ese kwekukuvara kunoitwawo nemukoti kudzivirira ganda kana hutachiona hutachiona, izvo zvinogona kuve zvakakomba uye nekuwedzera kukanganisa hutano hwemurwere.

Kana maronda aya asvika pane mucosa, kudyisa kunogona kuomera munhu uye, nekudaro, chikafu chinoiswa mukati mehasha kusvika iyo mucous membranes yapora.

Kuti kuderedze kusagadzikana kunokonzerwa nezvironda, kumanikidza kwemvura inotonhorera kana kushandiswa kwemafuta asina kwazvakarerekera kunogona kushandiswa kusimudzira ganda remvura. Uye zvakare, chiremba anogona zvakare kukurudzira kushandiswa kwemaanti-allergener, corticosteroids kana maantibayoti, semuenzaniso, kana iyo NET ichikonzerwa nehutachiona kana kana murwere awana hutachiona semhedzisiro yechirwere uye izvo zvinogona kukuvadza kiriniki mamiriro .

Maitiro ekuongororwa kunoitwa

Iko kuongororwa kunoitwa kunyanya zvichienderana nehunhu hwezvironda. Iko hakuna bvunzo yerabhoritari iyo inogona kuratidza kuti ndeupi mushonga unokonzeresa chirwere uye bvunzo dzekusimudzira hadziratidzwe mune ino kesi, sezvo inogona kukonzeresa kuti chirwere chiwedzere. Nekudaro, zvakakosha kuti munhu azivise chiremba kana aine chero chirwere kana kana akashandisa chero mushonga, kuitira kuti chiremba agone kusimbisa kuongororwa kwechirwere uye kuziva chinokonzera chinokonzera.

Uye zvakare, kuti asimbise kuongororwa, chiremba anowanzokumbira bhiopsy yeganda, kuwedzera kune yakazara ropa kuverenga, microbiological bvunzo dzeropa, weti uye ronda secretion, kutarisa chero hutachiona, uye kuyerwa kwezvimwe zvinhu zvinokonzeresa immune mhinduro.