Phenylalanine: Bhenefiti, Side Mhedzisiro uye Zvekudya Zvitubu

Zvemukati

• Chii chinonzi Phenylalanine?
• Izvo Zvakakosha kune Zvakajairika Kushanda kweMuviri Wako
• Inogona Kuva Inobatsira kune Mamwe Mamiriro Ekurapa
• Side Migumisiro
• Kudya Kwakakwirira muPhenylalanine
• Icho Chinokosha

Phenylalanine iamino acid inowanikwa mune zvakawanda zvekudya uye inoshandiswa nemuviri wako kugadzira mapuroteni uye mamwe akakosha mamorekuru.

Yakave yakadzidziswa nezve ayo mhedzisiro kuora mwoyo, kurwadziwa uye ganda kusagadzikana.

Ichi chinyorwa chinokuudza zvese zvaunoda kuti uzive nezve phenylalanine, kusanganisira mabhenefiti ayo, mhedzisiro uye zvekudya zvekudya.

Chii chinonzi Phenylalanine?

Phenylalanine amino acid, ayo ari anovaka mapuroteni mumuviri wako.

Morekuru iri riripo nenzira mbiri kana marongero: L-phenylalanine uye D-phenylalanine. Ivo vakada kufanana asi vane imwe yakati siyanei mamorekuru chimiro ().

Iyo L-fomu inowanikwa mune zvekudya uye inoshandiswa kugadzira mapuroteni mumuviri wako, nepo iyo D-fomu inogona kugadzirwa kuti ishandiswe mune mamwe marapirwo ekushandisa (2, 3).

Muviri wako haugone kuburitsa L-phenylalanine yakakwana pachayo, saka inoonekwa seinokosha amino acid inofanirwa kuwanikwa kuburikidza nekudya kwako (4).

Inowanikwa mune dzakasiyana siyana chikafu - zvese zvirimwa zvemhuka nemhuka ().

Kunze kwebasa rayo mukugadzira mapuroteni, phenylalanine inoshandiswa kugadzira mamwe mamorekuru akakosha mumuviri wako, akati wandei ayo anotumira masaini pakati pezvikamu zvakasiyana zvemuviri wako ().

Phenylalanine akafundwa senzira yekurapa kweakawanda marapirwo mamiriro, kusanganisira kusagadzikana kweganda, kushushikana uye kurwadziwa (3).

Zvisinei, zvinogona kuva nengozi kune vanhu vane genetic disorder phenylketonuria (PKU) (7).

Phenylalanine inokosha amino acid iyo inoshandiswa kugadzira mapuroteni uye kuratidza mamorekuru. Yakave ichidzidziswa senzira yekurapa kweakawanda marapirwo asi zvine njodzi kune avo vane yakatarwa geni kusagadzikana.

Izvo Zvakakosha kune Zvakajairika Kushanda kweMuviri Wako

Muviri wako unoda phenylalanine uye mamwe maamino acids kugadzira mapuroteni.

Mapuroteni mazhinji akakosha anowanikwa muuropi, ropa, mhasuru, nhengo dzemukati uye chero kwese kwese mumuviri wako.

Uyezve, phenylalanine yakakosha mukugadzirwa kwemamwe mamorekuru, kusanganisira (3):

• Tyrosine: Iyi amino acid inogadzirwa yakananga kubva phenylalanine. Inogona kushandiswa kugadzira mapuroteni matsva kana kushandurwa kuita mamwe mamorekuru pane ino runyorwa (,).
• Epinephrine uye norepinephrine: Paunosangana nekushushikana, mamorekuru aya akakosha kumhinduro yemuviri wako "yekurwa kana kubhururuka" ().
• Dopamine: Iyi mamorekuru inobatanidzwa mukunzwa kwekunakidzwa muuropi hwako, pamwe nekugadzira ndangariro uye hunyanzvi hwekufunda ().

Matambudziko neakajairika mashandiro emamorekuru aya anogona kukonzeresa hutano hutano (,).

Sezvo phenylalanine ichishandiswa kugadzira aya mamorekuru mumuviri wako, yakadzidzwa senge inogona kurapwa kune mamwe mamiriro, kusanganisira kushushikana ().

Phenylalanine inogona kushandurwa kuita amino acid tyrosine, iyo inozoshandiswa kugadzira akakosha ekuratidzira mamorekuru. Aya mamorekuru akabatanidzwa muzvinhu zvemuviri wako kujairika kushanda, kusanganisira yako manzwiro uye kushushikana mhinduro.

Inogona Kuva Inobatsira kune Mamwe Mamiriro Ekurapa

Ongororo dzinoverengeka dzakaongorora kana phenylalanine inogona kubatsira pakurapa mamwe marapirwo.

Kumwe kutsvagurudza kwakaratidza kuti inogona kushanda pakurapa vitiligo, chirwere cheganda chinokonzera kurasikirwa kweganda reganda uye kudzima ().

Zvimwe zvidzidzo zvakataura kuti kuwedzera phenylalanine zvinowedzera kune ultraviolet (UV) kujekesa mwenje kunogona kuvandudza ganda pigmentation mune vanhu vane mamiriro aya (,).

Phenylalanine inogona kushandiswa kuburitsa mamorekuru dopamine. Dopamine kusashanda muuropi inosanganiswa nedzimwe nzira dzekushungurudzika (,).

Imwe diki gumi nemaviri-munhu kudzidza yakaratidza mukana ungabatsirika wemusanganiswa weD- uye L-mafomu eiyi amino acid yekurapa kushushikana, iine 2/3 yevarwere inoratidza kuvandudza ().

Nekudaro, pane kushoma kumwe kutsigirwa kwemhedzisiro ye phenylalanine pane kushushikana, uye zvidzidzo zvakawanda hazvina kuwana mabhenefiti akajeka (,,).

Kuwedzera kune vitiligo uye kushushikana, phenylalanine akave akafundwa nezve zvinogona kuitika pa:

• Marwadzo: Iyo D-fomu ye phenylalanine inogona kupa kutapudza kwekurwadziwa mune dzimwe nguva, asi mhedzisiro yekudzidza yakasanganiswa (2,,,).
• Kunwa Doro: Chishoma chekutsvagisa chinoratidza kuti iyi amino acid, pamwe nemamwe maamino acids, inogona kubatsira kudzikisira zviratidzo zvekubvisa doro ().
• Chirwere chePasinson: Hushoma kwazvo humbowo hunoratidza kuti phenylalanine inogona kubatsira pakurapa chirwere chaParkinson, asi zvimwe zvidzidzo zvinodiwa ().
• ADHD: Parizvino, kutsvagurudza hakuratidze mabhenefiti eiyi amino acid yekurapa kwekucherechedza kushomeka kwehutano hwehutachiona (ADHD) (,).

Phenylalanine inogona kubatsira pakurapa kusagadzikana kweganda vitiligo. Uchapupu hahupe rutsigiro rwakasimba rwekushanda kweiyi amino acid pakurapa mamwe mamiriro, kunyangwe kushomeka kwemhando yepamusoro kwakaitwa.

Side Migumisiro

Phenylalanine inowanikwa mune akawanda mapuroteni-ane chikafu uye "inowanzozivikanwa seyakachengeteka" neKudya neDrug Administration (FDA) (27).

Huwandu hweiyi amino acid inowanikwa mune zvekudya haifanire kuisa njodzi kune vamwe vanhu vane hutano.

Zvakare, mashoma kana asina mhedzisiro anowanzoonekwa pakuwedzera doses ye23-45 mg paundi (50-100 mg pa kg) yehuremu hwemuviri (,).

Nekudaro, zvinogona kunge zviri nani kune vakadzi vane nhumbu kudzivirira kutora phenylalanine zvinowedzera.

Pamusoro pezvo, pane yakasarudzika yakasarudzika kune chengetedzo yakajairika yeiyi amino acid.

Vanhu vane amino acid metabolism chirwere phenylketonuria (PKU) havakwanise kugadzirisa phenylalanine nemazvo. Vanogona kunge vaine kuwanda kwe phenylalanine muropa ravo zvinokwana mazana mana zvakapetwa kupfuura izvo zvisina PKU (3, 7).

Izvi zvine njodzi zvakanyanya kukonzeresa zvinogona kukonzera kukuvara kwehuropi uye hurema hwekuziva, pamwe nezvinetso nekutakura kwemamwe amino acids kuuropi (7,).

Nekuda kwekukura kwechirwere ichi, vacheche vanowanzoongororwa PKU vachangoberekwa.

Vanhu vane PKU vanoiswa pane yakakosha-mapuroteni chikafu, icho chinowanzo chengeterwa kwehupenyu hwese (7).

Phenylalanine inoonekwa seyakachengeteka muhuwandu hunowanikwa mune zvakajairwa chikafu. Nekudaro, vanhu vane chirwere phenylketonuria (PKU) havagone kuisa metabolism iyi amino acid uye vanofanirwa kudzikisira kushandiswa nekuda kwemhedzisiro yehutano.

Kudya Kwakakwirira muPhenylalanine

Zvikafu zvakawanda zvine phenylalanine, zvinosanganisira zvese zvirimwa nemhuka zvigadzirwa.

Zvigadzirwa zveSoy zvimwe zvezvakanyanya kunaka masisitimu eamino acid, pamwe nedzimwe mbeu nenzungu, kusanganisira soya, mbeu yemanhanga uye mhodzi dze squash ().

Soy protein inowedzera inogona kupa anenge 2.5 magiramu e phenylalanine pa200-koriori inoshumira (, 29).

Zvezvigadzirwa zvemhuka, mazai, hove dzegungwa uye dzimwe nyama zviwanikwa zvakanaka, zvichipa kusvika kumagiramu matatu pamazana maviri-macalorie achishumira (, 29).

Pakazara, pamwe haufanire kusarudza zvakasarudzika zvekudya zvinoenderana nepamusoro phenylalanine zvemukati.

Kudya zvakasiyana-siyana zveprotein-zvakapfuma zvekudya mukati mezuva rese zvinokupa iwe zvese phenylalanine iwe zvaunoda, pamwe nezvimwe zvakakosha amino acids.

Zvikafu zvakawanda, zvinosanganisira zvigadzirwa zesoya, mazai, hove uye nyama, zvine phenylalanine. Kudya zvakasiyana-siyana zveprotein-zvakapfuma zvekudya mukati mezuva rese zvinokupa iwe ese maamino acids anodiwa nemuviri wako, kusanganisira phenylalanine.

Icho Chinokosha

Phenylalanine inokosha amino asidhi inowanikwa mune zvese zvirimwa zvemhuka nemhuka.

Inogona kunge iine mabhenefiti kune iyo ganda kusagadzikana vitiligo, asi kutsvagisa nezve ayo mhedzisiro yekushungurudzika, kurwadziwa kana mamwe mamiriro acho mashoma.

Inowanzoonekwa yakachengeteka, asi vanhu vane phenylketonuria (PKU) vanogona kusangana nenjodzi mhedzisiro.